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Research Article

Bayesian Reconstruction of Disease Outbreaks by Combining Epidemiologic and Genomic Data

  • Thibaut Jombart mail,

    t.jombart@imperial.ac.uk (TJ); c.fraser@imperial.ac.uk (CF)

    Affiliation: MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

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  • Anne Cori,

    Affiliation: MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

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  • Xavier Didelot,

    Affiliation: MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

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  • Simon Cauchemez,

    Affiliation: MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

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  • Christophe Fraser mail,

    t.jombart@imperial.ac.uk (TJ); c.fraser@imperial.ac.uk (CF)

    Affiliation: MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

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  • Neil Ferguson

    Affiliation: MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

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  • Published: January 23, 2014
  • DOI: 10.1371/journal.pcbi.1003457

About the Authors

Thibaut Jombart, Anne Cori, Xavier Didelot, Simon Cauchemez, Christophe Fraser, Neil Ferguson
MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TJ AC XD SC CF NF. Performed the experiments: TJ. Analyzed the data: TJ. Contributed reagents/materials/analysis tools: TJ. Wrote the paper: TJ AC XD SC CF NF. Designed the software ‘outbreaker’: TJ.