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Research Article

Optimal Serotype Compositions for Pneumococcal Conjugate Vaccination under Serotype Replacement

  • Markku Nurhonen mail,

    markku.nurhonen@thl.fi

    Affiliation: Department of Vaccination and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

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  • Kari Auranen

    Affiliation: Department of Vaccination and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

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  • Published: February 13, 2014
  • DOI: 10.1371/journal.pcbi.1003477

About the Authors

Markku Nurhonen, Kari Auranen
Department of Vaccination and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

Corresponding Author

Email: markku.nurhonen@thl.fi

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Analyzed the data: MN KA. Wrote the paper: MN KA. Developed the mathematical model: MN KA. Developed the computational approach: MN KA.