About the Authors

Armin Töpfer

Affiliations Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland, SIB Swiss Institute of Bioinformatics, Basel, Switzerland

Tobias Marschall

Affiliation Centrum Wiskunde & Informatica, Amsterdam, The Netherlands

Rowena A. Bull

Affiliation Inflammation and Infection Research Centre, School of Medical Sciences, UNSW, Sydney, Australia

Fabio Luciani

Affiliation Inflammation and Infection Research Centre, School of Medical Sciences, UNSW, Sydney, Australia

Alexander Schönhuth

Contributed equally to this work with: Alexander Schönhuth, Niko Beerenwinkel

Affiliation Centrum Wiskunde & Informatica, Amsterdam, The Netherlands

Niko Beerenwinkel

Contributed equally to this work with: Alexander Schönhuth, Niko Beerenwinkel

niko.beerenwinkel@bsse.ethz.ch

Affiliations Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland, SIB Swiss Institute of Bioinformatics, Basel, Switzerland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RAB FL AS NB. Performed the experiments: RAB FL. Analyzed the data: AT TM. Contributed reagents/materials/analysis tools: RAB FL. Wrote the paper: AT TM RAB FL AS NB. Developed the model: AT TM AS NB. Implemented the software: AT TM. Performed simulation studies: AT.