The image shows predicted functional linkage gene networks for large and small cytoplasmic ribosomal subunits in eukaryotes, derived from phylogenetic analysis of whole genomes. Each point represents a gene, and each line a functional link. Colors represent protein functional classes. (See Barker and Pagel)
Image Credit: Drawn by Barker and Pagel using BioLayout software.
Editorial
PLoS Computational Biology: A New Community Journal
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010004
Message from ISCB
An Open Forum for Computational Biology
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010005
Perspective
“Antedisciplinary” Science
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010006
Review
The Human Connectome: A Structural Description of the Human Brain
PLOS Computational Biology: published September 30, 2005 | https://doi.org/10.1371/journal.pcbi.0010042
Research Articles
Ab Initio Prediction of Transcription Factor Targets Using Structural Knowledge
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010001
What Makes Ribosome-Mediated Transcriptional Attenuation Sensitive to Amino Acid Limitation?
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010002
Predicting Functional Gene Links from Phylogenetic-Statistical Analyses of Whole Genomes
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010003
Susceptibility to Superhelically Driven DNA Duplex Destabilization: A Highly Conserved Property of Yeast Replication Origins
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010007
Combinatorial Pattern Discovery Approach for the Folding Trajectory Analysis of a β-Hairpin
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010008
Improving the Precision of the Structure–Function Relationship by Considering Phylogenetic Context
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010009
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Extraction of Transcript Diversity from Scientific Literature
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010010
A Phenomenological Theory of Spatially Structured Local Synaptic Connectivity
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010011
The Genomic Pattern of tDNA Operon Expression in E. coli
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010012
microRNA Target Predictions across Seven Drosophila Species and Comparison to Mammalian Targets
PLOS Computational Biology: published June 24, 2005 | https://doi.org/10.1371/journal.pcbi.0010013