Shown here is a symmetric model of tetrameric acetylcholinesterase assembled with collagen Q tail (yellow in the middle). The peripheral anionic site residues are shown as cyan, and the catalytic residue serine 203 is shown as green balls (see Zhang and McCammon).
Image Credit: Image created by David Zhang using VMD v1.8.4.
Message from ISCB
Bioinformatics Education—Perspectives and Challenges
PLOS Computational Biology: published November 25, 2005 | https://doi.org/10.1371/journal.pcbi.0010052
Perspective
NIH Roadmap Interdisciplinary Research Initiatives
PLOS Computational Biology: published November 25, 2005 | https://doi.org/10.1371/journal.pcbi.0010059
Review
Quasispecies Made Simple
PLOS Computational Biology: published November 25, 2005 | https://doi.org/10.1371/journal.pcbi.0010061
Research Articles
Genomic Variability within an Organism Exposes Its Cell Lineage Tree
PLOS Computational Biology: published October 28, 2005 | https://doi.org/10.1371/journal.pcbi.0010050
Use of Artificial Genomes in Assessing Methods for Atypical Gene Detection
PLOS Computational Biology: published November 11, 2005 | https://doi.org/10.1371/journal.pcbi.0010056
A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes
PLOS Computational Biology: published November 11, 2005 | https://doi.org/10.1371/journal.pcbi.0010060
The Association of Tetrameric Acetylcholinesterase with ColQ Tail: A Block Normal Mode Analysis
PLOS Computational Biology: published November 18, 2005 | https://doi.org/10.1371/journal.pcbi.0010062
Stealth Proteins: In Silico Identification of a Novel Protein Family Rendering Bacterial Pathogens Invisible to Host Immune Defense
PLOS Computational Biology: published November 18, 2005 | https://doi.org/10.1371/journal.pcbi.0010063
Quantitative Analysis of Genetic and Neuronal Multi-Perturbation Experiments
PLOS Computational Biology: published November 25, 2005 | https://doi.org/10.1371/journal.pcbi.0010064
Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis
PLOS Computational Biology: published November 25, 2005 | https://doi.org/10.1371/journal.pcbi.0010065
Refining Protein Subcellular Localization
PLOS Computational Biology: published November 25, 2005 | https://doi.org/10.1371/journal.pcbi.0010066