A protein's shape can be described by a series of points on the unit sphere. The blue regions at the poles of this spherical histogram do not occur in proteins (see Hamelryck et al).
Image Credit: Histogram made using R by Wouter Boomsma. Ray-traced version of the histogram mapped to spheres using POVRAY by Thomas Hamelryck.
Editorial
Ten Simple Rules for Reviewers
PLOS Computational Biology: published September 29, 2006 | https://doi.org/10.1371/journal.pcbi.0020110
Perspective
Scientific Software Development Is Not an Oxymoron
PLOS Computational Biology: published September 8, 2006 | https://doi.org/10.1371/journal.pcbi.0020087
Research Articles
Modeling of Oxygen Transport and Cellular Energetics Explains Observations on In Vivo Cardiac Energy Metabolism
PLOS Computational Biology: published September 15, 2006 | https://doi.org/10.1371/journal.pcbi.0020107
Evidence of Influence of Genomic DNA Sequence on Human X Chromosome Inactivation
PLOS Computational Biology: published September 1, 2006 | https://doi.org/10.1371/journal.pcbi.0020113
Model-Based Design of Growth-Attenuated Viruses
PLOS Computational Biology: published September 1, 2006 | https://doi.org/10.1371/journal.pcbi.0020116
Oscillatory Regulation of Hes1: Discrete Stochastic Delay Modelling and Simulation
PLOS Computational Biology: published September 8, 2006 | https://doi.org/10.1371/journal.pcbi.0020117
Imitating Manual Curation of Text-Mined Facts in Biomedicine
PLOS Computational Biology: published September 8, 2006 | https://doi.org/10.1371/journal.pcbi.0020118
Transient Calcium and Dopamine Increase PKA Activity and DARPP-32 Phosphorylation
PLOS Computational Biology: published September 8, 2006 | https://doi.org/10.1371/journal.pcbi.0020119
Mathematical Modeling Identifies Inhibitors of Apoptosis as Mediators of Positive Feedback and Bistability
PLOS Computational Biology: published September 15, 2006 | https://doi.org/10.1371/journal.pcbi.0020120
Intricate Knots in Proteins: Function and Evolution
PLOS Computational Biology: published September 15, 2006 | https://doi.org/10.1371/journal.pcbi.0020122
Transcriptional Dynamics of the Embryonic Stem Cell Switch
PLOS Computational Biology: published September 15, 2006 | https://doi.org/10.1371/journal.pcbi.0020123
The Many Faces of Protein–Protein Interactions: A Compendium of Interface Geometry
PLOS Computational Biology: published September 29, 2006 | https://doi.org/10.1371/journal.pcbi.0020124
Computational Model of Vascular Endothelial Growth Factor Spatial Distribution in Muscle and Pro-Angiogenic Cell Therapy
PLOS Computational Biology: published September 22, 2006 | https://doi.org/10.1371/journal.pcbi.0020127
Can Transgenic Maize Affect Soil Microbial Communities?
PLOS Computational Biology: published September 29, 2006 | https://doi.org/10.1371/journal.pcbi.0020128
Sampling Realistic Protein Conformations Using Local Structural Bias
PLOS Computational Biology: published September 22, 2006 | https://doi.org/10.1371/journal.pcbi.0020131
Phylogenetic Reconstruction of Orthology, Paralogy, and Conserved Synteny for Dog and Human
PLOS Computational Biology: published September 29, 2006 | https://doi.org/10.1371/journal.pcbi.0020133
Targeted Molecular Dynamics Study of C-Loop Closure and Channel Gating in Nicotinic Receptors
PLOS Computational Biology: published September 29, 2006 | https://doi.org/10.1371/journal.pcbi.0020134