Cell fate specification in C. elegans visualized with blue and yellow fluorescent proteins expressed in the primary and secondary vulval precursor cells, respectively. The markers were used to observe the temporal order in the activation of EGFR and LIN-12/Notch signaling pathways as predicted by computational modeling (see Fisher et al, e92).
Image Credit: Alex Hajnal
Editorial
Ten Simple Rules for a Good Poster Presentation
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030102
Message from ISCB
ISMB/ECCB 2007: The Premier Conference on Computational Biology
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030096
Research Articles
Stochastic Simulations on the Reliability of Action Potential Propagation in Thin Axons
PLOS Computational Biology: published May 4, 2007 | https://doi.org/10.1371/journal.pcbi.0030079
Cooperative Gating and Spatial Organization of Membrane Proteins through Elastic Interactions
PLOS Computational Biology: published May 4, 2007 | https://doi.org/10.1371/journal.pcbi.0030081
Integrated Mechanisms of Anticipation and Rate-of-Change Computations in Cortical Circuits
PLOS Computational Biology: published May 11, 2007 | https://doi.org/10.1371/journal.pcbi.0030082
Enhancer Responses to Similarly Distributed Antagonistic Gradients in Development
PLOS Computational Biology: published May 11, 2007 | https://doi.org/10.1371/journal.pcbi.0030084
Can Influenza Epidemics Be Prevented by Voluntary Vaccination?
PLOS Computational Biology: published May 4, 2007 | https://doi.org/10.1371/journal.pcbi.0030085
HIV-1 Subtype B Protease and Reverse Transcriptase Amino Acid Covariation
PLOS Computational Biology: published May 11, 2007 | https://doi.org/10.1371/journal.pcbi.0030087
Binding Site Graphs: A New Graph Theoretical Framework for Prediction of Transcription Factor Binding Sites
PLOS Computational Biology: published May 11, 2007 | https://doi.org/10.1371/journal.pcbi.0030090
A First Look at ARFome: Dual-Coding Genes in Mammalian Genomes
PLOS Computational Biology: published May 18, 2007 | https://doi.org/10.1371/journal.pcbi.0030091
Predictive Modeling of Signaling Crosstalk during C. elegans Vulval Development
PLOS Computational Biology: published May 18, 2007 | https://doi.org/10.1371/journal.pcbi.0030092
The Human Genomic Melting Map
PLOS Computational Biology: published May 18, 2007 | https://doi.org/10.1371/journal.pcbi.0030093
Prediction of Functional Sites Based on the Fuzzy Oil Drop Model
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030094
The Emergence of Alternative 3′ and 5′ Splice Site Exons from Constitutive Exons
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030095
Bang-Bang Control of Feeding: Role of Hypothalamic and Satiety Signals
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030097
Related Articles
Comprehensive DNA Signature Discovery and Validation
PLOS Computational Biology: published May 18, 2007 | https://doi.org/10.1371/journal.pcbi.0030098
Frequent Gain and Loss of Functional Transcription Factor Binding Sites
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030099
Related Articles
Correspondence
“Simple Rules for Editors”? Here is One Rule to Tackle Neglected Problems of Publishing
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030088
Related Articles
“Simple Rules for Editors”? Here Is One Rule to Tackle Neglected Problems of Publishing: Response from PLoS
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030089
Related Articles
Correction
Correction: Persistent Activity in Neural Networks with Dynamic Synapses
PLOS Computational Biology: published May 25, 2007 | https://doi.org/10.1371/journal.pcbi.0030104