Table of Contents: September 2007


Synthetic "dead-leaves" image

Image Credit: Image by David Corney and R. Beau Lotto (
Issue Image

Natural images occupy a small subset of the high-dimensional manifold of possible images, and are therefore characterized by certain statistical properties. The image shown here is a synthetic "dead-leaves" image, which preserves many of the statistical structures common to natural images. Artificial neural networks were trained to recognize surfaces within these images under illumination that vary in space and time, with the result that the trained networks exhibited responses commensurate with human lightness illusions (see Corney and Lotto, e180).


Developing Computational Biology

Philip E Bourne, Steven E Brenner



Research Articles

A Computational Approach to the Functional Screening of Genomes

Davide Chiarugi, Pierpaolo Degano, Roberto Marangoni

Organization and Evolution of Primate Centromeric DNA from Whole-Genome Shotgun Sequence Data

Can Alkan, Mario Ventura, Nicoletta Archidiacono, Mariano Rocchi, S. Cenk Sahinalp, Evan E Eichler

Bistability and Oscillations in the Huang-Ferrell Model of MAPK Signaling

Liang Qiao, Robert B Nachbar, Ioannis G Kevrekidis, Stanislav Y Shvartsman

Structure-Templated Predictions of Novel Protein Interactions from Sequence Information

Doron Betel, Kevin E Breitkreuz, Ruth Isserlin, Danielle Dewar-Darch, Mike Tyers, Christopher W. V Hogue

Structural Reorganisation and Potential Toxicity of Oligomeric Species Formed during the Assembly of Amyloid Fibrils

Mookyung Cheon, Iksoo Chang, Sandipan Mohanty, Leila M Luheshi, Christopher M Dobson, Michele Vendruscolo, Giorgio Favrin

A Macaque's-Eye View of Human Insertions and Deletions: Differences in Mechanisms

Erika M Kvikstad, Svitlana Tyekucheva, Francesca Chiaromonte, Kateryna D Makova

Characterization of Protein Hubs by Inferring Interacting Motifs from Protein Interactions

Ramon Aragues, Andrej Sali, Jaume Bonet, Marc A Marti-Renom, Baldo Oliva

A Balanced Memory Network

Yasser Roudi, Peter E Latham



Correction: Adaptive, Fast Walking in a Biped Robot under Neuronal Control and Learning

Poramate Manoonpong, Tao Geng, Tomas Kulvicius, Bernd Porr, Florentin Wörgötter