Cover
Screen capture of data analysis console displaying predicted haplogroup and supporting evidence
The tabular background is values for human Y chromosome microsatellite repeats with the predicted haplogroup for a sample highlighted with a dashed yellow oval. The evolutionary history of the haplogroup is traced in red on the human Y chromosome gene tree; haplogroups traversed during the prediction process and corresponding confidence values are displayed in grey in the lower section of the montage (see Schlecht et al., doi:10.1371/journal.pcbi.1000093).
Image Credit: Nirav Merchant
Editorials
Ten Simple Rules for Organizing a Scientific Meeting
PLOS Computational Biology: published June 27, 2008 | https://doi.org/10.1371/journal.pcbi.1000080
How To Advance Open International Scientific Exchange
PLOS Computational Biology: published June 27, 2008 | https://doi.org/10.1371/journal.pcbi.1000097
Message from ISCB
ISMB 2008 Toronto
PLOS Computational Biology: published June 27, 2008 | https://doi.org/10.1371/journal.pcbi.1000094
Research Articles
A Comparative Computer Simulation of Dendritic Morphology
PLOS Computational Biology: published June 6, 2008 | https://doi.org/10.1371/journal.pcbi.1000089
CSMET: Comparative Genomic Motif Detection via Multi-Resolution Phylogenetic Shadowing
PLOS Computational Biology: published June 6, 2008 | https://doi.org/10.1371/journal.pcbi.1000090
Integrated Information in Discrete Dynamical Systems: Motivation and Theoretical Framework
PLOS Computational Biology: published June 13, 2008 | https://doi.org/10.1371/journal.pcbi.1000091
Machine-Learning Approaches for Classifying Haplogroup from Y Chromosome STR Data
PLOS Computational Biology: published June 13, 2008 | https://doi.org/10.1371/journal.pcbi.1000093
Dynamics and Potential Impact of the Immune Response to Chronic Myelogenous Leukemia
PLOS Computational Biology: published June 20, 2008 | https://doi.org/10.1371/journal.pcbi.1000095
Model-Based Hypothesis Testing of Key Mechanisms in Initial Phase of Insulin Signaling
PLOS Computational Biology: published June 20, 2008 | https://doi.org/10.1371/journal.pcbi.1000096
How To Record a Million Synaptic Weights in a Hippocampal Slice
PLOS Computational Biology: published June 20, 2008 | https://doi.org/10.1371/journal.pcbi.1000098
Regulation of Signal Duration and the Statistical Dynamics of Kinase Activation by Scaffold Proteins
PLOS Computational Biology: published June 27, 2008 | https://doi.org/10.1371/journal.pcbi.1000099
Network Analysis of Intrinsic Functional Brain Connectivity in Alzheimer's Disease
PLOS Computational Biology: published June 27, 2008 | https://doi.org/10.1371/journal.pcbi.1000100