When displaced from their regular routes, workers of the Australian desert ant Melophorus bagoti rotate on the spot, producing visual scans of the world, before setting off in a seemingly purposeful manner. In this image a worker with her prized cookie crumb is photographed on a goniometer that is used to record her directional choice. (See Baddeley et al., doi:10.1371/journal.pcbi.1002336)
Image Credit: Antoine Wystrach (University of Sussex, Brighton, UK)
Editorial
A Review of 2011 for PLoS Computational Biology
PLOS Computational Biology: published January 26, 2012 | https://doi.org/10.1371/journal.pcbi.1002387
Perspective
Beyond Statistical Significance: Implications of Network Structure on Neuronal Activity
PLOS Computational Biology: published January 26, 2012 | https://doi.org/10.1371/journal.pcbi.1002311
Review
Computational and Statistical Analysis of Protein Mass Spectrometry Data
PLOS Computational Biology: published January 26, 2012 | https://doi.org/10.1371/journal.pcbi.1002296
Research Articles
A Feedback Quenched Oscillator Produces Turing Patterning with One Diffuser
PLOS Computational Biology: published January 26, 2012 | https://doi.org/10.1371/journal.pcbi.1002331
Balancing Feed-Forward Excitation and Inhibition via Hebbian Inhibitory Synaptic Plasticity
PLOS Computational Biology: published January 26, 2012 | https://doi.org/10.1371/journal.pcbi.1002334
Macro-level Modeling of the Response of C. elegans Reproduction to Chronic Heat Stress
PLOS Computational Biology: published January 26, 2012 | https://doi.org/10.1371/journal.pcbi.1002338
Single Sample Expression-Anchored Mechanisms Predict Survival in Head and Neck Cancer
PLOS Computational Biology: published January 26, 2012 | https://doi.org/10.1371/journal.pcbi.1002350
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Senescent Cells in Growing Tumors: Population Dynamics and Cancer Stem Cells
PLOS Computational Biology: published January 19, 2012 | https://doi.org/10.1371/journal.pcbi.1002316
Learning and Generalization under Ambiguity: An fMRI Study
PLOS Computational Biology: published January 19, 2012 | https://doi.org/10.1371/journal.pcbi.1002346
A Theory of Rate Coding Control by Intrinsic Plasticity Effects
PLOS Computational Biology: published January 19, 2012 | https://doi.org/10.1371/journal.pcbi.1002349
Dynamic Modelling under Uncertainty: The Case of Trypanosoma brucei Energy Metabolism
PLOS Computational Biology: published January 19, 2012 | https://doi.org/10.1371/journal.pcbi.1002352
Membrane Properties and the Balance between Excitation and Inhibition Control Gamma-Frequency Oscillations Arising from Feedback Inhibition
PLOS Computational Biology: published January 19, 2012 | https://doi.org/10.1371/journal.pcbi.1002354
HIV-1 Polymerase Inhibition by Nucleoside Analogs: Cellular- and Kinetic Parameters of Efficacy, Susceptibility and Resistance Selection
PLOS Computational Biology: published January 19, 2012 | https://doi.org/10.1371/journal.pcbi.1002359
Prediction by Promoter Logic in Bacterial Quorum Sensing
PLOS Computational Biology: published January 19, 2012 | https://doi.org/10.1371/journal.pcbi.1002361
Parsimonious Higher-Order Hidden Markov Models for Improved Array-CGH Analysis with Applications to Arabidopsis thaliana
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002286
Lipid Exchange Mechanism of the Cholesteryl Ester Transfer Protein Clarified by Atomistic and Coarse-grained Simulations
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002299
Global Analysis of Small Molecule Binding to Related Protein Targets
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002333
Protein Design Using Continuous Rotamers
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002335
A Dynamic View of Domain-Motif Interactions
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002341
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Adjusting Phenotypes by Noise Control
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002344
Network Model of Immune Responses Reveals Key Effectors to Single and Co-infection Dynamics by a Respiratory Bacterium and a Gastrointestinal Helminth
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002345
Maximization of Learning Speed in the Motor Cortex Due to Neuronal Redundancy
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002348
Kinetic Rate Constant Prediction Supports the Conformational Selection Mechanism of Protein Binding
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002351
Residual Structures, Conformational Fluctuations, and Electrostatic Interactions in the Synergistic Folding of Two Intrinsically Disordered Proteins
PLOS Computational Biology: published January 12, 2012 | https://doi.org/10.1371/journal.pcbi.1002353
Short Conduction Delays Cause Inhibition Rather than Excitation to Favor Synchrony in Hybrid Neuronal Networks of the Entorhinal Cortex
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002306
Multi-scale Inference of Interaction Rules in Animal Groups Using Bayesian Model Selection
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002308
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Failure of Adaptive Self-Organized Criticality during Epileptic Seizure Attacks
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002312
Dopamine, Affordance and Active Inference
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002327
Landscape Epidemiology and Control of Pathogens with Cryptic and Long-Distance Dispersal: Sudden Oak Death in Northern Californian Forests
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002328
A Dynamical Model of Oocyte Maturation Unveils Precisely Orchestrated Meiotic Decisions
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002329
Joint Modelling of Confounding Factors and Prominent Genetic Regulators Provides Increased Accuracy in Genetical Genomics Studies
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002330
A Model of Ant Route Navigation Driven by Scene Familiarity
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002336
A Mathematical Methodology for Determining the Temporal Order of Pathway Alterations Arising during Gliomagenesis
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002337
A Viral Dynamic Model for Treatment Regimens with Direct-acting Antivirals for Chronic Hepatitis C Infection
PLOS Computational Biology: published January 5, 2012 | https://doi.org/10.1371/journal.pcbi.1002339