Local regions of natural images contain rich information about form and texture. Psychophysical experiments show that human observers are remarkably sensitive to these natural image regularities. Indeed, the visual system seems to know much more about the regularities in natural images than any current probabilistic model, even at very fine scales. These fail to capture contrast fluctuations and local contour information—features to which human observers are highly sensitive. See Gerhard et al.
Image Credit: Holly E. Gerhard, Werner Reichardt Centre for Integrative Neuroscience
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Don't Wear Your New Shoes (Yet): Taking the Right Steps to Become a Successful Principal Investigator
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002834
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Visual Data Mining of Biological Networks: One Size Does Not Fit All
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002833
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Approximate Bayesian Computation
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002803
Research Articles
Ribosome Traffic on mRNAs Maps to Gene Ontology: Genome-wide Quantification of Translation Initiation Rates and Polysome Size Regulation
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002866
Integrating Phylodynamics and Epidemiology to Estimate Transmission Diversity in Viral Epidemics
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002876
Maximizing the Information Content of Experiments in Systems Biology
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002888
Temporal Adaptation Enhances Efficient Contrast Gain Control on Natural Images
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002889
Membrane Sculpting by F-BAR Domains Studied by Molecular Dynamics Simulations
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002892
Bayesian Inference of Spatial Organizations of Chromosomes
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002893
Starling Flock Networks Manage Uncertainty in Consensus at Low Cost
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002894
Activity in Inferior Parietal and Medial Prefrontal Cortex Signals the Accumulation of Evidence in a Probability Learning Task
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002895
Using Steered Molecular Dynamics to Predict and Assess Hsp70 Substrate-Binding Domain Mutants that Alter Prion Propagation
PLOS Computational Biology: published January 31, 2013 | https://doi.org/10.1371/journal.pcbi.1002896
Divide and Conquer: Functional Segregation of Synaptic Inputs by Astrocytic Microdomains Could Alleviate Paroxysmal Activity Following Brain Trauma
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002856
Dynamic Finite Size Effects in Spiking Neural Networks
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002872
How Sensitive Is the Human Visual System to the Local Statistics of Natural Images?
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002873
Significance Analysis of Prognostic Signatures
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002875
Assembly of the Transmembrane Domain of E. coli PhoQ Histidine Kinase: Implications for Signal Transduction from Molecular Simulations
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002878
Important miRs of Pathways in Different Tumor Types
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002883
Positional Bias of MHC Class I Restricted T-Cell Epitopes in Viral Antigens Is Likely due to a Bias in Conservation
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002884
The Human Functional Brain Network Demonstrates Structural and Dynamical Resilience to Targeted Attack
PLOS Computational Biology: published January 24, 2013 | https://doi.org/10.1371/journal.pcbi.1002885
The Effects of City Streets on an Urban Disease Vector
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002801
How Evolving Heterogeneity Distributions of Resource Allocation Strategies Shape Mortality Patterns
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002825
Identifying Transmission Cycles at the Human-Animal Interface: The Role of Animal Reservoirs in Maintaining Gambiense Human African Trypanosomiasis
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002855
ADEMA: An Algorithm to Determine Expected Metabolite Level Alterations Using Mutual Information
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002859
Evolutionary Optimization of Protein Folding
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002861
Effects of Ligand Binding on the Mechanical Properties of Ankyrin Repeat Protein Gankyrin
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002864
Reward from Punishment Does Not Emerge at All Costs
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002868
Oroxylin A Inhibits Hemolysis via Hindering the Self-Assembly of α-Hemolysin Heptameric Transmembrane Pore
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002869
Durable Resistance to Crop Pathogens: An Epidemiological Framework to Predict Risk under Uncertainty
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002870
Saccadic Momentum and Facilitation of Return Saccades Contribute to an Optimal Foraging Strategy
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002871
An Integrative Model of Ion Regulation in Yeast
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002879
Metallochaperones Regulate Intracellular Copper Levels
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002880
Binding of Nucleoid-Associated Protein Fis to DNA Is Regulated by DNA Breathing Dynamics
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002881
Redirector: Designing Cell Factories by Reconstructing the Metabolic Objective
PLOS Computational Biology: published January 17, 2013 | https://doi.org/10.1371/journal.pcbi.1002882
Integration of the Transcriptome and Glycome for Identification of Glycan Cell Signatures
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002813
Computational Analysis of Rho GTPase Cycling
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002831
Phosphorylation Variation during the Cell Cycle Scales with Structural Propensities of Proteins
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002842
Modelling Growth and Form of the Scleractinian Coral Pocillopora verrucosa and the Influence of Hydrodynamics
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002849
The Effects of Temperature on the Stability of a Neuronal Oscillator
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002857
Asymmetric PTEN Distribution Regulated by Spatial Heterogeneity in Membrane-Binding State Transitions
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002862
A Guide to Enterotypes across the Human Body: Meta-Analysis of Microbial Community Structures in Human Microbiome Datasets
PLOS Computational Biology: published January 10, 2013 | https://doi.org/10.1371/journal.pcbi.1002863
Refractoriness in Sustained Visuo-Manual Control: Is the Refractory Duration Intrinsic or Does It Depend on External System Properties?
PLOS Computational Biology: published January 3, 2013 | https://doi.org/10.1371/journal.pcbi.1002843
Network Self-Organization Explains the Statistics and Dynamics of Synaptic Connection Strengths in Cortex
PLOS Computational Biology: published January 3, 2013 | https://doi.org/10.1371/journal.pcbi.1002848
Phyletic Profiling with Cliques of Orthologs Is Enhanced by Signatures of Paralogy Relationships
PLOS Computational Biology: published January 3, 2013 | https://doi.org/10.1371/journal.pcbi.1002852
Identification of a Functional Connectome for Long-Term Fear Memory in Mice
PLOS Computational Biology: published January 3, 2013 | https://doi.org/10.1371/journal.pcbi.1002853
Adding Protein Context to the Human Protein-Protein Interaction Network to Reveal Meaningful Interactions
PLOS Computational Biology: published January 3, 2013 | https://doi.org/10.1371/journal.pcbi.1002860
The Underlying Molecular and Network Level Mechanisms in the Evolution of Robustness in Gene Regulatory Networks
PLOS Computational Biology: published January 3, 2013 | https://doi.org/10.1371/journal.pcbi.1002865