The electrostatic field forms three distinctive funnels leading to the vicinity of the active sites. These funnels serve as electrostatic guide for the positively charged spermidine substrate. Coloring scale data range: -1; 1 (blue, positive; red, negative). Calculated with DelPhi and visualized with VMD. See Zhang, et al.
Image Credit: Marharyta Petukh, Zhe Zhang, Emil Alexov, Clemson University
Editorial
Let's Make Those Book Chapters Open Too!
PLOS Computational Biology: published February 21, 2013 | https://doi.org/10.1371/journal.pcbi.1002941
Research Articles
Passive Dendrites Enable Single Neurons to Compute Linearly Non-separable Functions
PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002867
Discriminating External and Internal Causes for Heading Changes in Freely Flying Drosophila
PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002891
Virus Neutralisation: New Insights from Kinetic Neutralisation Curves
PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002900
Characterizing the Relationship between Steady State and Response Using Analytical Expressions for the Steady States of Mass Action Models
PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002901
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An Entropic Mechanism of Generating Selective Ion Binding in Macromolecules
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Collective States, Multistability and Transitional Behavior in Schooling Fish
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Spartan: A Comprehensive Tool for Understanding Uncertainty in Simulations of Biological Systems
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Standard Anatomical and Visual Space for the Mouse Retina: Computational Reconstruction and Transformation of Flattened Retinae with the Retistruct Package
PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002921
Functional Connectivity in Islets of Langerhans from Mouse Pancreas Tissue Slices
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Enhancing Human Spermine Synthase Activity by Engineered Mutations
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Dynamic Modeling of Cell Migration and Spreading Behaviors on Fibronectin Coated Planar Substrates and Micropatterned Geometries
PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002926
No Evidence for an Item Limit in Change Detection
PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002927
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PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002931
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PLOS Computational Biology: published February 28, 2013 | https://doi.org/10.1371/journal.pcbi.1002932
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Viral Capsid Proteins Are Segregated in Structural Fold Space
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PLOS Computational Biology: published February 7, 2013 | https://doi.org/10.1371/journal.pcbi.1002912