Journal Archive

Current Issue


COMPASS - A Software for Accurate and Rapid Backbone Resonance Assignments of Proteins.

The image represents a signal in a three-dimensional NMR spectrum being assigned to a specific nucleus of the protein backbone. The multi-platform software COMPASS, as presented by Niklasson et al., was developed for this purpose. COMPASS was designed to be suitable for resonance assignments of small-to-large proteins from complete or limited data sets. User friendliness was also a priority when designing the software. Advantages over competing software include increased user control of the entire backbone assignment process and instant feedback on assignments in the form of a graphical representation of the calculated secondary structure.

Image Credit: Markus Niklasson