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Table of Contents | July 2008

 
 

Message from ISCB

ISCB Honors David Haussler and Aviv Regev

Clare Sansom, B. J. Morrison McKay

 

Perspective

Outlook on Thailand's Genomics and Computational Biology Research and Development

Wannipha Tongsima, Sissades Tongsima, Prasit Palittapongarnpim

Computational Biology Resources Lack Persistence and Usability

Stella Veretnik, J. Lynn Fink, Philip E. Bourne

 

Review

Nonnegative Matrix Factorization: An Analytical and Interpretive Tool in Computational Biology

Karthik Devarajan

 

Research Article

Decoding of Superimposed Traces Produced by Direct Sequencing of Heterozygous Indels

Dmitry A. Dmitriev, Roman A. Rakitov

Author Summary

Predicting and Validating Protein Interactions Using Network Structure

Pao-Yang Chen, Charlotte M. Deane, Gesine Reinert

Author Summary

Isolation-by-Distance and Outbreeding Depression Are Sufficient to Drive Parapatric Speciation in the Absence of Environmental Influences

Guy A. Hoelzer, Rich Drewes, Jeffrey Meier, René Doursat

Author Summary

The Spatiotemporal Pattern of Src Activation at Lipid Rafts Revealed by Diffusion-Corrected FRET Imaging

Shaoying Lu, Mingxing Ouyang, Jihye Seong, Jin Zhang, Shu Chien, Yingxiao Wang

Author Summary

Optimal Compensation for Temporal Uncertainty in Movement Planning

Todd E. Hudson, Laurence T. Maloney, Michael S. Landy

Author Summary

Protein Complex Evolution Does Not Involve Extensive Network Rewiring

Teunis J. P. van Dam, Berend Snel

Author Summary

Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms

Tammy M. K. Cheng, Yu-En Lu, Michele Vendruscolo, Pietro Lio', Tom L. Blundell

Author Summary

Dynamics of Immune Escape during HIV/SIV Infection

Christian L. Althaus, Rob J. De Boer

Author Summary

The Ascent of the Abundant: How Mutational Networks Constrain Evolution

Matthew C. Cowperthwaite, Evan P. Economo, William R. Harcombe, Eric L. Miller, Lauren Ancel Meyers

Author Summary

Similarity Queries for Temporal Toxicogenomic Expression Profiles

Adam A. Smith, Aaron Vollrath, Christopher A. Bradfield, Mark Craven

Author Summary

Intrinsic Gain Modulation and Adaptive Neural Coding

Sungho Hong, Brian Nils Lundstrom, Adrienne L. Fairhall

Author Summary

Memory Switches in Chemical Reaction Space

Naren Ramakrishnan, Upinder S. Bhalla

Author Summary

Emergent Synchronous Bursting of Oxytocin Neuronal Network

Enrico Rossoni, Jianfeng Feng, Brunello Tirozzi, David Brown, Gareth Leng, Françoise Moos

Author Summary

Unraveling Protein Networks with Power Graph Analysis

Loïc Royer, Matthias Reimann, Bill Andreopoulos, Michael Schroeder

Author Summary

The Generation of Promoter-Mediated Transcriptional Noise in Bacteria

Namiko Mitarai, Ian B. Dodd, Michael T. Crooks, Kim Sneppen

Author Summary

Active Nuclear Receptors Exhibit Highly Correlated AF-2 Domain Motions

Denise G. Teotico, Monica L. Frazier, Feng Ding, Nikolay V. Dokholyan, Brenda R. S. Temple, Matthew R. Redinbo

Author Summary

Evolution of Evolvability in Gene Regulatory Networks

Anton Crombach, Paulien Hogeweg

Author Summary

Probing the Extent of Randomness in Protein Interaction Networks

Joseph Ivanic, Anders Wallqvist, Jaques Reifman

Author Summary

Using Expression Profiles of Caenorhabditis elegans Neurons To Identify Genes That Mediate Synaptic Connectivity

Leehod Baruch, Shalev Itzkovitz, Michal Golan-Mashiach, Ehud Shapiro, Eran Segal

Author Summary

Kinetic Modeling of the Assembly, Dynamic Steady State, and Contraction of the FtsZ Ring in Prokaryotic Cytokinesis

Ivan V. Surovtsev, Jeffrey J. Morgan, Paul A. Lindahl

Author Summary

Circadian Phase Resetting via Single and Multiple Control Targets

Neda Bagheri, Jörg Stelling, Francis J. Doyle

Author Summary

Local Function Conservation in Sequence and Structure Space

Nils Weinhold, Oliver Sander, Francisco S. Domingues, Thomas Lengauer, Ingolf Sommer

Author Summary

Increased Brain Signal Variability Accompanies Lower Behavioral Variability in Development

Anthony Randal McIntosh, Natasa Kovacevic, Roxane J. Itier

Author Summary

Quantitative Predictions of Peptide Binding to Any HLA-DR Molecule of Known Sequence: NetMHCIIpan

Morten Nielsen, Claus Lundegaard, Thomas Blicher, Bjoern Peters, Alessandro Sette, Sune Justesen, Søren Buus, Ole Lund

Author Summary

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