Table of Contents: December 2006


Region of the Protein Homology Network

Image Credit: Illustration by Giorgio Corsi
Issue Image

Closeup view of a region of the Protein Homology Network (PHN) that allows displaying either the homology relationships within a family or the genetic distance between the members. Protein families show a high density of connections. Different colors identify VirB1, AvhB1, VirB4, TraH, Slt, and TrbN bacterial families (See Covacci et al).



Research Articles

Prediction of Amyloidogenic and Disordered Regions in Protein Chains

Oxana V Galzitskaya, Sergiy O Garbuzynskiy, Michail Yurievich Lobanov

DARPP-32 Is a Robust Integrator of Dopamine and Glutamate Signals

Éric Fernandez, Renaud Schiappa, Jean-Antoine Girault, Nicolas Le Novère

Computational Reconstruction of Iron- and Manganese-Responsive Transcriptional Networks in α-Proteobacteria

Dmitry A Rodionov, Mikhail S Gelfand, Jonathan D Todd, Andrew R. J Curson, Andrew W. B Johnston

Insight into the Structure of Amyloid Fibrils from the Analysis of Globular Proteins

Antonio Trovato, Fabrizio Chiti, Amos Maritan, Flavio Seno

Detecting Statistically Significant Common Insertion Sites in Retroviral Insertional Mutagenesis Screens

Jeroen de Ridder, Anthony Uren, Jaap Kool, Marcel Reinders, Lodewyk Wessels

Transcriptional Regulation by Competing Transcription Factor Modules

Rutger Hermsen, Sander Tans, Pieter Rein ten Wolde