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Research Article

Sensitivity Analysis of Intracellular Signaling Pathway Kinetics Predicts Targets for Stem Cell Fate Control

  • Alborz Mahdavi,

    Affiliations: Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

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  • Ryan E Davey,

    Affiliation: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

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  • Patrick Bhola,

    Affiliation: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

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  • Ting Yin,

    Affiliation: Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada

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  • Peter W Zandstra mail

    To whom correspondence should be addressed. E-mail: peter.zandstra@utoronto.ca

    Affiliations: Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

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  • Published: July 06, 2007
  • DOI: 10.1371/journal.pcbi.0030130

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