A First-Principles Model of Early Evolution: Emergence of Gene Families, Species, and Preferred Protein Folds

• Konstantin B Zeldovich,

  Affiliation Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

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• Peiqiu Chen,

  Affiliations Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America , Department of Physics, Harvard University, Cambridge, Massachusetts, United States of America

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• Boris E Shakhnovich,

  Affiliation Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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• Eugene I Shakhnovich

  *To whom correspondence should be addressed. E-mail: eugene@belok.harvard.edu

  Affiliation Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

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