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Research Article

On State-Space Reduction in Multi-Strain Pathogen Models, with an Application to Antigenic Drift in Influenza A

  • Sergey Kryazhimskiy mail,

    To whom correspondence should be addressed. E-mail: skryazhi@princeton.edu

    Affiliation: Program in Applied and Computational Mathematics, Princeton University, Princeton, New Jersey, United States of America

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  • Ulf Dieckmann,

    Affiliation: Evolution and Ecology Program, International Institute for Applied Systems Analysis, Laxenburg, Austria

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  • Simon A Levin,

    Affiliation: Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Jonathan Dushoff

    Affiliations: Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America, Fogarty International Center, National Institute of Health, Bethesda, Maryland, United States of America

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  • Published: August 17, 2007
  • DOI: 10.1371/journal.pcbi.0030159

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