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Research Article

Active Nuclear Receptors Exhibit Highly Correlated AF-2 Domain Motions

  • Denise G. Teotico,

    Affiliation: Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Monica L. Frazier,

    Affiliation: Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Feng Ding,

    Affiliation: Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Nikolay V. Dokholyan,

    Affiliations: Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, The Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Brenda R. S. Temple,

    Affiliation: University of North Carolina RL Juliano Structural Bioinformatics Core Facility, Chapel Hill, North Carolina, United States of America

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  • Matthew R. Redinbo mail

    redinbo@unc.edu

    Affiliations: Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, The Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Published: July 11, 2008
  • DOI: 10.1371/journal.pcbi.1000111

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