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Research Article

Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells

  • Murat Cirit,

    Affiliation: Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America

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  • Matej Krajcovic,

    Affiliation: Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America

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  • Colin K. Choi,

    Affiliation: Department of Cell Biology, University of Virginia, Charlottesville, Virginia, United States of America

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  • Erik S. Welf,

    Affiliation: Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America

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  • Alan F. Horwitz,

    Affiliation: Department of Cell Biology, University of Virginia, Charlottesville, Virginia, United States of America

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  • Jason M. Haugh mail

    jason_haugh@ncsu.edu

    Affiliation: Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America

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  • Published: February 26, 2010
  • DOI: 10.1371/journal.pcbi.1000688

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