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Research Article

Rule-Based Cell Systems Model of Aging using Feedback Loop Motifs Mediated by Stress Responses

  • Andres Kriete mail,

    andres.kriete@drexel.edu

    Affiliation: School of Biomedical Engineering, Science and Health Systems, Drexel University, Bossone Research Center, Philadelphia, Pennsylvania, United States of America

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  • William J. Bosl,

    Affiliation: Harvard Medical School, Children's Hospital Informatics Program, Boston, Massachusetts, United States of America

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  • Glenn Booker

    Affiliations: School of Biomedical Engineering, Science and Health Systems, Drexel University, Bossone Research Center, Philadelphia, Pennsylvania, United States of America, College of Information Science and Technology, Drexel University, Philadelphia, Pennsylvania, United States of America

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  • Published: June 17, 2010
  • DOI: 10.1371/journal.pcbi.1000820

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