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Research Article

Evolution of a Signaling Nexus Constrained by Protein Interfaces and Conformational States

  • Brenda R. S. Temple mail,

    btemple@med.unc.edu

    Affiliations: R. L. Juliano Structural Bioinformatics Core Facility, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Corbin D. Jones,

    Affiliations: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Alan M. Jones

    Affiliations: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Published: October 14, 2010
  • DOI: 10.1371/journal.pcbi.1000962

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