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Research Article

Causal Modeling Using Network Ensemble Simulations of Genetic and Gene Expression Data Predicts Genes Involved in Rheumatoid Arthritis

  • Heming Xing,

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • Paul D. McDonagh mail,

    mcdonagh@gnsbiotech.com

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • Jadwiga Bienkowska,

    Affiliation: Biogen Idec, Cambridge, Massachusetts, United States of America

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  • Tanya Cashorali,

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • Karl Runge,

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • Robert E. Miller,

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • Dave DeCaprio,

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • Bruce Church,

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • Ronenn Roubenoff,

    Affiliation: Biogen Idec, Cambridge, Massachusetts, United States of America

    Current address: Novartis Institute of Biomedical Research, Cambridge, Massachusetts, United States of America

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  • Iya G. Khalil,

    Affiliation: Gene Network Sciences, Cambridge, Massachusetts, United States of America

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  • John Carulli

    Affiliation: Biogen Idec, Cambridge, Massachusetts, United States of America

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  • Published: March 10, 2011
  • DOI: 10.1371/journal.pcbi.1001105

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