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Research Article

Switches, Excitable Responses and Oscillations in the Ring1B/Bmi1 Ubiquitination System

  • Lan K. Nguyen equal contributor,

    equal contributor Contributed equally to this work with: Lan K. Nguyen, Javier Muñoz-García

    Affiliation: Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland

    X
  • Javier Muñoz-García equal contributor,

    equal contributor Contributed equally to this work with: Lan K. Nguyen, Javier Muñoz-García

    Affiliation: Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland

    X
  • Helene Maccario,

    Affiliation: Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland

    X
  • Aaron Ciechanover,

    Affiliation: Cancer and Vascular Biology Research Center, The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Bat Galim, Haifa, Israel

    X
  • Walter Kolch,

    Affiliation: Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland

    X
  • Boris N. Kholodenko mail

    boris.kholodenko@ucd.ie

    Affiliations: Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Published: December 15, 2011
  • DOI: 10.1371/journal.pcbi.1002317

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