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Research Article

The Impact of Oxygen on Metabolic Evolution: A Chemoinformatic Investigation

  • Ying-Ying Jiang equal contributor,

    equal contributor Contributed equally to this work with: Ying-Ying Jiang, De-Xin Kong

    Affiliations: National Key Laboratory of Crop Genetic Improvement, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China, Center for Bioinformatics, Huazhong Agricultural University, Wuhan, China

    Current address: Biochemical Engineering Institute, Saarland University, Saarbrücken, Germany

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  • De-Xin Kong equal contributor,

    equal contributor Contributed equally to this work with: Ying-Ying Jiang, De-Xin Kong

    Affiliations: Center for Bioinformatics, Huazhong Agricultural University, Wuhan, China, State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China

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  • Tao Qin,

    Affiliation: School of Life Sciences, Shandong University of Technology, Zibo, China

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  • Xiao Li,

    Affiliation: School of Life Sciences, Shandong University of Technology, Zibo, China

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  • Gustavo Caetano-Anollés,

    Affiliation: Evolutionary Bioinformatics Laboratory, Department of Crop Sciences, University of Illinois, Urbana, Illinois, United States of America

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  • Hong-Yu Zhang mail

    zhy630@mail.hzau.edu.cn

    Affiliations: National Key Laboratory of Crop Genetic Improvement, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China, Center for Bioinformatics, Huazhong Agricultural University, Wuhan, China

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  • Published: March 15, 2012
  • DOI: 10.1371/journal.pcbi.1002426

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