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Research Article

Automatic Filtering and Substantiation of Drug Safety Signals

  • Anna Bauer-Mehren,

    Affiliation: Research Programme on Biomedical Informatics (GRIB), IMIM-Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain

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  • Erik M. van Mullingen,

    Affiliation: Erasmus University Medical Center, Rotterdam, The Netherlands

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  • Paul Avillach,

    Affiliations: LESIM-ISPED, Université de Bordeaux, Bordeaux, France, LERTIM, EA 3283, Faculté de Médecine, Université de Aix-Marseille, Marseille, France

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  • María del Carmen Carrascosa,

    Affiliation: Research Programme on Biomedical Informatics (GRIB), IMIM-Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain

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  • Ricard Garcia-Serna,

    Affiliation: Research Programme on Biomedical Informatics (GRIB), IMIM-Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain

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  • Janet Piñero,

    Affiliation: Research Programme on Biomedical Informatics (GRIB), IMIM-Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain

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  • Bharat Singh,

    Affiliation: Erasmus University Medical Center, Rotterdam, The Netherlands

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  • Pedro Lopes,

    Affiliation: DETI/IEETA, Universidade de Aveiro, Aveiro, Portugal

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  • José L. Oliveira,

    Affiliation: DETI/IEETA, Universidade de Aveiro, Aveiro, Portugal

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  • Gayo Diallo,

    Affiliation: LESIM-ISPED, Université de Bordeaux, Bordeaux, France

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  • Ernst Ahlberg Helgee,

    Affiliation: AstraZeneca, Mölndal, Sweden

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  • Scott Boyer,

    Affiliation: AstraZeneca, Mölndal, Sweden

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  • Jordi Mestres,

    Affiliation: Research Programme on Biomedical Informatics (GRIB), IMIM-Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain

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  • Ferran Sanz,

    Affiliation: Research Programme on Biomedical Informatics (GRIB), IMIM-Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain

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  • Jan A. Kors,

    Affiliation: Erasmus University Medical Center, Rotterdam, The Netherlands

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  • Laura I. Furlong mail

    lfurlong@imim.es

    Affiliation: Research Programme on Biomedical Informatics (GRIB), IMIM-Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.pcbi.1002457

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