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Research Article

Ligand-Dependent Conformations and Dynamics of the Serotonin 5-HT2A Receptor Determine Its Activation and Membrane-Driven Oligomerization Properties

  • Jufang Shan,

    Affiliation: Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York, United States of America

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  • George Khelashvili,

    Affiliation: Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York, United States of America

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  • Sayan Mondal,

    Affiliation: Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York, United States of America

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  • Ernest L. Mehler,

    Affiliation: Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York, United States of America

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  • Harel Weinstein mail

    haw2002@med.cornell.edu

    Affiliations: Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York, United States of America, The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Medical College of Cornell University, New York, New York, United States of America

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  • Published: April 19, 2012
  • DOI: 10.1371/journal.pcbi.1002473

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