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Research Article

Substrate-Specific Reorganization of the Conformational Ensemble of CSK Implicates Novel Modes of Kinase Function

  • Michael A. Jamros,

    Affiliation: Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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  • Leandro C. Oliveira,

    Affiliation: Laboratório Nacional de Ciência e Tecnologia do Bioetanol – CTBE/CNPEM, Campinas, São Paulo, Brazil

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  • Paul C. Whitford,

    Affiliation: Center for Theoretical Biological Physics, Rice University, Houston, Texas, United States of America

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  • José N. Onuchic,

    Affiliation: Center for Theoretical Biological Physics, Rice University, Houston, Texas, United States of America

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  • Joseph A. Adams,

    Affiliation: Department of Pharmacology, University of California San Diego, La Jolla, California, United States of America

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  • Patricia A. Jennings mail

    pajennin@ucsd.edu

    Affiliation: Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

    X
  • Published: September 20, 2012
  • DOI: 10.1371/journal.pcbi.1002695

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