Biological Process Baits with the GO term GO GO Descr. Species P-val P-val (corrected) Count sum(f_hat) sum(n) mean(alpha) GO:0008150 biological process +GO:0065007 biological regulation yeast 0.00001 0.033 294 415.15 3660 0.11 +-GO:0065009 regulation of a molecular function fly 0.000006 0.024 15 61.61 227 0.27 +--GO:0050790 regulation of catalytic activity fly 0.0000002 0.0008 14 61.61 207 0.3 +-GO:0050789 regulation of biological process +--GO:0048519 negative regulation of biological process +---GO:0048523 negative regulation of cellular process +----GO:0031324 negative regulation of cellular metabolic process +-----GO:0045934 "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process " +------GO:0016481 negative regulation of transcription +-------GO:0045892 "negative regulation of transcription, DNA-dependent " +--------GO:0006342 chromatin silencing yeast 0.000002 0.006 21 41.71 212 0.2 +---------GO:0006348 chromatin silencing at telomere yeast 0.000000004 0.00001 10 38.63 153 0.25 +---GO:0045814 "negative regulation of gene expression, epigenetic " yeast 0.000002 0.006 21 41.71 212 0.2 +--GO:0050794 regulation of cellular process +---GO:0051726 regulation of cell cycle +----GO:0000074 regulation of progression through cell cycle +-----GO:0000075 cell cycle checkpoint yeast 2.00E-12 0.000000007 10 38.51 122 0.32 +---GO:0031323 regulation of cellular metabolic process +----GO:0019219 "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process " +-----GO:0045449 regulation of transcription yeast 0.0000001 0.0003 131 215.39 1636 0.13 +------GO:0006355 "regulation of transcription, DNA-dependent " yeast 0.00000004 0.0001 124 210.73 1570 0.13 +--GO:0040029 "regulation of gene expression, epigenetic " yeast 0.000002 0.007 22 41.78 213 0.2 +--GO:0040008 regulation of growth +---GO:0040014 regulation of body size worm 0.00003 0.025 5 37.62 157 0.24 +-GO:0065008 regulation of biological quality +--GO:0042592 homeostatic process yeast 3.00E-18 1.00E-14 30 77.88 289 0.27 +---GO:0019725 cell homeostasis yeast 1.00E-18 4.00E-15 28 77.24 285 0.27 +----GO:0006873 cell ion homeostasis yeast 4.00E-19 1.00E-15 19 72.84 251 0.29 +-----GO:0030003 cation homeostasis yeast 7.00E-20 2.00E-16 16 72.7 244 0.3 +------GO:0030004 monovalent inorganic cation homeostasis yeast 2.00E-21 5.00E-18 8 72.35 230 0.31 +-------GO:0030641 hydrogen ion homeostasis yeast 1.00E-21 4.00E-18 7 72.28 229 0.32 +--------GO:0051453 regulation of cellular pH yeast 1.00E-21 4.00E-18 7 72.28 229 0.32 +---------GO:0051452 cellular pH reduction yeast 1.00E-21 4.00E-18 7 72.28 229 0.32 +----------GO:0007035 vacuolar acidification yeast 1.00E-21 4.00E-18 7 72.28 229 0.32 +---GO:0048878 chemical homeostasis yeast 3.00E-19 9.00E-16 21 73.48 255 0.29 +----GO:0050801 ion homeostasis yeast 3.00E-19 9.00E-16 21 73.48 255 0.29 +-----GO:0006885 regulation of pH yeast 4.00E-21 1.00E-17 9 72.92 233 0.31 +------GO:0045851 pH reduction yeast 1.00E-21 4.00E-18 7 72.28 229 0.32 +GO:0009987 cellular process +-GO:0007154 cell communication worm 0.000003 0.003 19 50.2 715 0.07 +--GO:0007165 signal transduction worm 0.00000002 0.00002 15 36.91 638 0.06 +---GO:0007166 cell surface receptor linked signal transduction worm 0.00001 0.011 7 20.68 365 0.06 +-GO:0007049 cell cycle +--GO:0022402 cell cycle process +---GO:0022403 cell cycle phase +----GO:0000279 M phase +-----GO:0051327 M phase of meiotic cell cycle +------GO:0007126 meiosis +-------GO:0007143 female meiosis +--------GO:0016321 female meiosis chromosome segregation fly 0.000004 0.015 10 44.9 146 0.31 +-GO:0048468 cell development +--GO:0022607 cellular component assembly +---GO:0031497 chromatin assembly yeast 0.000002 0.007 22 41.78 213 0.2 +----GO:0031507 heterochromatin formation yeast 0.000002 0.006 21 41.71 212 0.2 +-----GO:0031509 telomeric heterochromatin formation yeast 0.000000004 0.00001 10 38.63 153 0.25 +---GO:0065003 macromolecular complex assembly fly 0.000009 0.036 60 107.76 984 0.11 +--GO:0000904 cellular morphogenesis during differentiation +---GO:0048667 neuron morphogenesis during differentiation fly 0.0000002 0.0009 27 39.64 491 0.08 +----GO:0048812 neurite morphogenesis fly 0.0000002 0.0009 27 39.64 491 0.08 +-----GO:0007409 axonogenesis fly 0.0000002 0.0009 27 39.64 491 0.08 +------GO:0007411 axon guidance fly 0.00000001 0.00006 17 21.3 354 0.06 +--GO:0022008 neurogenesis +---GO:0048699 generation of neurons fly 0.000002 0.01 47 83.64 820 0.1 +----GO:0030182 neuron differentiation fly 0.0000001 0.0005 37 54.82 626 0.09 +-----GO:0048666 neuron development fly 0.00000003 0.0001 34 46.31 573 0.08 +------GO:0031175 neurite development fly 0.00000003 0.0001 34 46.31 573 0.08 +-GO:0045165 cell fate commitment +--GO:0001708 cell fate specification fly 0.000005 0.02 14 69.85 264 0.26 +-GO:0016043 cellular component organization and biogenesis yeast 0.000005 0.017 568 617.75 5614 0.11 +--GO:0051641 cellular localization yeast 2.00E-10 0.0000007 195 309.74 2346 0.13 +---GO:0051649 establishment of cellular localization yeast 1.00E-10 0.0000004 191 309.6 2336 0.13 +----GO:0046907 intracellular transport yeast 5.00E-11 0.0000001 176 303.6 2259 0.13 +-----GO:0016197 endosome transport +------GO:0045324 late endosome to vacuole transport yeast 0.000001 0.004 6 27.96 114 0.25 +-----GO:0048193 Golgi vesicle transport fly 0.0000004 0.002 6 38.19 111 0.34 +------GO:0006888 ER to Golgi vesicle-mediated transport fly 0.0000001 0.0004 5 35.54 94 0.38 +-----GO:0006886 intracellular protein transport yeast 0.00001 0.032 104 177.28 1396 0.13 +------GO:0006605 protein targeting yeast 0.0000002 0.0005 81 168.05 1226 0.14 +-------GO:0006611 protein export from nucleus yeast 3.00E-15 9.00E-12 20 99.55 469 0.21 +-------GO:0006606 protein import into nucleus yeast 4.00E-10 0.000001 19 148.92 960 0.16 +--------GO:0006609 mRNA-binding (hnRNP) protein import into nucleus yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +--------GO:0006607 NLS-bearing substrate import into nucleus yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +--------GO:0006610 ribosomal protein import into nucleus yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +--------GO:0006608 snRNP protein import into nucleus yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +-----GO:0051169 nuclear transport yeast 0.000000007 0.00002 35 152.44 1033 0.15 +------GO:0051168 nuclear export yeast 2.00E-13 6.00E-10 31 103.86 529 0.2 +-------GO:0006405 RNA export from nucleus yeast 9.00E-15 3.00E-11 27 102.72 498 0.21 +--------GO:0006406 mRNA export from nucleus yeast 2.00E-15 5.00E-12 24 100.37 472 0.21 +--------GO:0006407 rRNA export from nucleus yeast 1.00E-15 3.00E-12 14 79.48 330 0.24 +--------GO:0006408 snRNA export from nucleus yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +--------GO:0006409 tRNA export from nucleus yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +------GO:0051170 nuclear import yeast 4.00E-10 0.000001 19 148.92 960 0.16 +-----GO:0006913 nucleocytoplasmic transport yeast 0.000000007 0.00002 35 152.44 1033 0.15 +-----GO:0007034 vacuolar transport yeast 4.00E-20 1.00E-16 35 106.98 445 0.24 +--GO:0032989 cellular structure morphogenesis +---GO:0000902 cell morphogenesis +----GO:0048858 cell projection morphogenesis fly 0.0000004 0.001 39 58.37 646 0.09 +-----GO:0030030 cell projection organization and biogenesis fly 0.0000004 0.001 39 58.37 646 0.09 +---GO:0032990 cell part morphogenesis fly 0.0000004 0.001 39 58.37 646 0.09 +--GO:0043062 extracellular structure organization and biogenesis +---GO:0050808 synapse organization and biogenesis +----GO:0007416 synaptogenesis fly 0.000003 0.012 11 18.55 276 0.07 +--GO:0006996 organelle organization and biogenesis yeast 4.00E-13 0.000000001 323 431.79 3304 0.13 +---GO:0051276 chromosome organization and biogenesis +----GO:0007001 chromosome organization and biogenesis (sensu Eukaryota) +-----GO:0006325 establishment and/or maintenance of chromatin architecture +------GO:0006333 chromatin assembly or disassembly yeast 0.000002 0.007 26 42.52 220 0.19 +---GO:0006997 nuclear organization and biogenesis yeast 2.00E-14 6.00E-11 20 86.61 393 0.22 +----GO:0006999 nuclear pore organization and biogenesis yeast 1.00E-15 4.00E-12 15 82.31 350 0.24 +---GO:0042254 ribosome biogenesis and assembly +----GO:0006364 rRNA processing +-----GO:0006365 35S primary transcript processing yeast 0.000001 0.004 22 1.3 171 0.01 +---GO:0007033 vacuole organization and biogenesis yeast 6.00E-21 2.00E-17 17 76.41 257 0.3 +-GO:0048869 cellular developmental process +--GO:0030154 cell differentiation +---GO:0042386 hemocyte differentiation fly 0.000002 0.009 6 40.39 126 0.32 +-GO:0044237 cellular metabolic process +--GO:0009308 amine metabolic process +---GO:0009309 amine biosynthetic process +----GO:0008652 amino acid biosynthetic process +-----GO:0009070 serine family amino acid biosynthetic process yeast 2.00E-11 0.00000005 9 46.37 175 0.26 +---GO:0006520 amino acid metabolic process +----GO:0009069 serine family amino acid metabolic process yeast 9.00E-11 0.0000003 12 46.76 183 0.26 +-----GO:0006563 L-serine metabolic process yeast 5.00E-12 0.00000002 5 45.45 164 0.28 +--GO:0044249 cellular biosynthetic process yeast 0.000003 0.009 117 176.35 1357 0.13 +---GO:0051188 cofactor biosynthetic process yeast 0.00000002 0.00006 24 89.16 531 0.17 +----GO:0009108 coenzyme biosynthetic process yeast 0.00000002 0.00005 19 88.88 521 0.17 +-----GO:0006754 ATP biosynthetic process yeast 3.00E-12 0.000000009 5 84.46 414 0.2 +------GO:0015986 ATP synthesis coupled proton transport yeast 3.00E-12 0.000000009 5 84.46 414 0.2 +---GO:0009165 nucleotide biosynthetic process yeast 0.000002 0.006 29 94.03 629 0.15 +----GO:0009142 nucleoside triphosphate biosynthetic process yeast 1.00E-11 0.00000004 9 85.53 433 0.2 +-----GO:0009145 purine nucleoside triphosphate biosynthetic process yeast 4.00E-12 0.00000001 7 84.6 416 0.2 +------GO:0009206 purine ribonucleoside triphosphate biosynthetic process yeast 4.00E-12 0.00000001 7 84.6 416 0.2 +-----GO:0009201 ribonucleoside triphosphate biosynthetic process yeast 1.00E-11 0.00000004 9 85.53 433 0.2 +----GO:0006164 purine nucleotide biosynthetic process yeast 0.000000006 0.00002 16 87.64 503 0.17 +-----GO:0009152 purine ribonucleotide biosynthetic process yeast 0.000000005 0.00002 15 87.57 502 0.17 +----GO:0009260 ribonucleotide biosynthetic process yeast 0.00000001 0.00004 17 88.5 519 0.17 +--GO:0044248 cellular catabolic process +---GO:0044265 cellular macromolecule catabolic process +----GO:0044257 cellular protein catabolic process +-----GO:0051603 proteolysis involved in cellular protein catabolic process +------GO:0019941 modification-dependent protein catabolic process +-------GO:0006511 ubiquitin-dependent protein catabolic process +--------GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body pathway yeast 0.00001 0.039 5 28.81 134 0.22 +--GO:0051186 cofactor metabolic process yeast 0.00000008 0.0003 40 94.42 588 0.16 +---GO:0046034 ATP metabolic process yeast 3.00E-12 0.000000009 5 84.46 414 0.2 +---GO:0006732 coenzyme metabolic process yeast 0.00000006 0.0002 33 91.07 560 0.16 +----GO:0006752 group transfer coenzyme metabolic process yeast 8.00E-12 0.00000002 10 84.67 422 0.2 +-----GO:0006753 nucleoside phosphate metabolic process yeast 3.00E-12 0.000000009 5 84.46 414 0.2 +--GO:0043094 metabolic compound salvage +---GO:0043174 nucleoside salvage yeast 0.00001 0.038 7 1.62 145 0.01 +----GO:0006166 purine ribonucleoside salvage yeast 0.00001 0.038 7 1.62 145 0.01 +---GO:0043101 purine salvage yeast 0.00001 0.038 7 1.62 145 0.01 +--GO:0006139 "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process " yeast 0.0000004 0.001 400 478.68 4142 0.12 +---GO:0006259 DNA metabolic process yeast 0.000002 0.005 141 159.89 1193 0.13 +----GO:0006281 DNA repair yeast 1.00E-12 0.000000004 55 114.51 625 0.18 +-----GO:0006289 nucleotide-excision repair fly 0.00001 0.044 6 43.64 147 0.3 +---GO:0016458 gene silencing yeast 0.000002 0.006 21 41.71 212 0.2 +---GO:0009116 nucleoside metabolic process yeast 0.000003 0.009 11 1.76 161 0.01 +----GO:0042278 purine nucleoside metabolic process yeast 0.00001 0.035 8 1.69 146 0.01 +-----GO:0046128 purine ribonucleoside metabolic process yeast 0.00001 0.035 8 1.69 146 0.01 +----GO:0009119 ribonucleoside metabolic process yeast 0.000005 0.015 9 1.69 155 0.01 +---GO:0009117 nucleotide metabolic process +----GO:0009141 nucleoside triphosphate metabolic process yeast 2.00E-11 0.00000005 11 85.67 435 0.2 +-----GO:0009144 purine nucleoside triphosphate metabolic process yeast 4.00E-12 0.00000001 7 84.6 416 0.2 +------GO:0009205 purine ribonucleoside triphosphate metabolic process yeast 4.00E-12 0.00000001 7 84.6 416 0.2 +-----GO:0009199 ribonucleoside triphosphate metabolic process yeast 1.00E-11 0.00000004 9 85.53 433 0.2 +----GO:0006163 purine nucleotide metabolic process yeast 0.000000006 0.00002 16 87.64 503 0.17 +-----GO:0009150 purine ribonucleotide metabolic process yeast 0.000000005 0.00002 15 87.57 502 0.17 +----GO:0009259 ribonucleotide metabolic process yeast 0.00000001 0.00004 17 88.5 519 0.17 +---GO:0016070 RNA metabolic process yeast 0.0000006 0.002 272 349.06 2924 0.12 +----GO:0032774 RNA biosynthetic process yeast 0.00000005 0.0002 133 212.41 1593 0.13 +-----GO:0006351 "transcription, DNA-dependent " yeast 0.00000005 0.0002 132 212.34 1592 0.13 +------GO:0006366 transcription from RNA polymerase II promoter yeast 0.00000005 0.0002 60 135.71 922 0.15 +----GO:0006396 RNA processing +-----GO:0008380 RNA splicing yeast 2.00E-11 0.00000007 37 77.18 380 0.2 +------GO:0000394 "RNA splicing, via endonucleolytic cleavage and ligation " yeast 6.00E-22 2.00E-18 6 68.27 206 0.33 +-------GO:0006388 tRNA splicing yeast 6.00E-22 2.00E-18 6 68.27 206 0.33 +-----GO:0008033 tRNA processing yeast 2.00E-18 7.00E-15 21 71.95 252 0.29 +----GO:0006399 tRNA metabolic process yeast 2.00E-16 6.00E-13 39 76.5 302 0.25 +---GO:0006350 transcription yeast 0.0000002 0.0006 143 218.33 1676 0.13 +--GO:0006793 phosphorus metabolic process yeast 0.000004 0.011 67 104.15 725 0.14 +---GO:0006796 phosphate metabolic process yeast 0.000004 0.011 67 104.15 725 0.14 +----GO:0016310 phosphorylation yeast 0.000006 0.019 57 100.9 699 0.14 +-----GO:0006119 oxidative phosphorylation yeast 1.00E-11 0.00000004 9 84.6 426 0.2 +GO:0032502 developmental process +-GO:0048856 anatomical structure development +--GO:0048513 organ development fly 0.000001 0.006 185 781.69 4256 0.18 +---GO:0048565 gut development fly 0.0000009 0.004 19 94.05 374 0.25 +----GO:0007494 midgut development fly 0.000000002 0.000008 6 49.66 136 0.37 +---GO:0048534 hemopoietic or lymphoid organ development +----GO:0030097 hemopoiesis fly 0.000002 0.009 11 55.4 193 0.29 +---GO:0007517 muscle development fly 0.000006 0.024 28 132.07 586 0.23 +GO:0051234 establishment of localization yeast 0.0000005 0.002 315 401.7 3414 0.12 +-GO:0045184 establishment of protein localization +--GO:0015031 protein transport +---GO:0017038 protein import yeast 5.00E-10 0.000002 31 150.65 979 0.15 +-GO:0051236 establishment of RNA localization yeast 3.00E-13 9.00E-10 32 106.86 553 0.19 +--GO:0050658 RNA transport yeast 3.00E-13 9.00E-10 32 106.86 553 0.19 +---GO:0051028 mRNA transport yeast 1.00E-13 5.00E-10 30 106.51 548 0.19 +---GO:0051029 rRNA transport yeast 1.00E-15 3.00E-12 14 79.48 330 0.24 +---GO:0051030 snRNA transport yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +---GO:0051031 tRNA transport yeast 4.00E-16 1.00E-12 12 79.13 325 0.24 +-GO:0006810 transport yeast 0.0000002 0.0007 308 398.01 3358 0.12 +--GO:0006818 hydrogen transport yeast 4.00E-12 0.00000001 7 84.85 417 0.2 +---GO:0015992 proton transport yeast 4.00E-12 0.00000001 7 84.85 417 0.2 +----GO:0015985 "energy coupled proton transport, down electrochemical gradient " yeast 3.00E-12 0.000000009 5 84.46 414 0.2 +--GO:0006811 ion transport yeast 3.00E-10 0.0000009 40 90.84 496 0.18 +---GO:0006812 cation transport yeast 3.00E-11 0.0000001 29 87.05 455 0.19 +----GO:0015672 monovalent inorganic cation transport yeast 5.00E-12 0.00000001 8 84.92 418 0.2 +--GO:0015931 "nucleobase, nucleoside, nucleotide and nucleic acid transport " yeast 2.00E-13 5.00E-10 35 107.07 556 0.19 +---GO:0050657 nucleic acid transport yeast 3.00E-13 9.00E-10 32 106.86 553 0.19 +-GO:0035264 multicellular organism growth worm 0.00003 0.025 5 37.62 157 0.24 +GO:0051179 localization worm|yeast 1.E-05|7.E-07 0.014|0.002 23|323 66.23|403.87 326|3444 0.20|0.12 +-GO:0033036 macromolecule localization +--GO:0006403 RNA localization yeast 5.00E-13 0.000000002 36 108.89 573 0.19 +GO:0008152 metabolic process +-GO:0009058 biosynthetic process fly|worm 6.E-07|1.E-06 0.002|0.001 205|8 284.24|9.5 2341|253 0.12|0.04 +--GO:0009059 macromolecule biosynthetic process worm 0.000001 0.001 5 8.46 240 0.04 +-GO:0006091 generation of precursor metabolites and energy yeast 0.000007 0.021 56 106.32 752 0.14 +GO:0050896 response to stimulus yeast 0.00000007 0.0002 187 215.89 1625 0.13 +-GO:0007610 behavior +--GO:0030537 larval behavior fly 0.00000001 0.00006 7 4.9 169 0.03 +---GO:0008345 larval locomotory behavior fly 0.00000001 0.00006 7 4.9 169 0.03 +--GO:0007611 learning and/or memory fly 0.000006 0.023 13 18.01 270 0.07 +---GO:0007613 memory fly 3.00E-10 0.000001 6 2.03 165 0.01 +-GO:0009719 response to endogenous stimulus yeast 2.00E-11 0.00000007 71 128.98 763 0.17 +--GO:0006974 response to DNA damage stimulus yeast 8.00E-12 0.00000002 69 128.98 751 0.17 +-GO:0006950 response to stress worm|yeast 2.E-06|3.E-10 0.002|1.e-06 8|133 32.01|195.87 528|1351 0.06|0.14