Molecular Function Baits with the GO term GO GO Descr. Species P-val P-val (corrected) Count sum(f_hat) sum(n) mean(alpha) GO:0003674 molecular function +GO:0005488 binding +-GO:0048037 cofactor binding yeast 0.000000001 0.000003 26 48.53 211 0.23 +--GO:0050662 coenzyme binding yeast 7.00E-10 0.000001 25 48.53 207 0.23 +---GO:0050660 FAD binding fly 0.000004 0.008 8 39.1 125 0.31 +---GO:0051287 NAD binding fly|yeast 3.E-06|2.E-11 0.006|3.e-08 8|6 11|46.2 207|175 0.05|0.26 +-GO:0043167 ion binding +--GO:0043169 cation binding yeast 0.000003 0.006 144 56.72 1033 0.05 +---GO:0046914 transition metal ion binding yeast 0.000003 0.005 128 53.73 996 0.05 +----GO:0008270 zinc ion binding yeast 0.00001 0.025 95 48.05 890 0.05 +-GO:0008289 lipid binding +--GO:0005543 phospholipid binding fly 0.00002 0.036 14 15.27 230 0.07 +---GO:0035091 phosphoinositide binding fly 0.00001 0.026 9 6.92 143 0.05 +-GO:0003676 nucleic acid binding +--GO:0003723 RNA binding fly 0.000001 0.002 98 203.76 1739 0.12 +-GO:0005515 protein binding fly 0.0000002 0.0004 2973 7090.12 47723 0.15 +--GO:0008092 cytoskeletal protein binding +---GO:0015631 tubulin binding fly 0.000003 0.005 8 3.94 120 0.03 +----GO:0008017 microtubule binding fly 0.000004 0.007 7 3.51 118 0.03 +--GO:0019899 enzyme binding fly 0.000002 0.004 8 39.19 122 0.32 +---GO:0019900 kinase binding fly 0.000009 0.017 6 31.31 94 0.33 +--GO:0042802 identical protein binding fly 9.00E-39 2.00E-35 105 171.89 2441 0.07 +GO:0003824 catalytic activity +-GO:0016787 hydrolase activity +--GO:0016817 "hydrolase activity, acting on acid anhydrides " yeast 0.000000001 0.000003 65 85.26 474 0.18 +---GO:0016820 "hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances " yeast 2.00E-24 4.00E-21 10 74.56 219 0.34 +----GO:0042626 "ATPase activity, coupled to transmembrane movement of substances " yeast 2.00E-24 4.00E-21 10 74.56 219 0.34 +-----GO:0042625 "ATPase activity, coupled to transmembrane movement of ions " yeast 1.00E-24 2.00E-21 8 74.42 217 0.34 +------GO:0019829 cation-transporting ATPase activity yeast 5.00E-25 8.00E-22 6 74.03 214 0.35 +-------GO:0046961 "hydrogen ion transporting ATPase activity, rotational mechanism " yeast 3.00E-27 5.00E-24 5 72.03 190 0.38 +---GO:0016818 "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides " yeast 0.000000001 0.000003 65 85.26 474 0.18 +----GO:0016462 pyrophosphatase activity yeast 0.000000001 0.000003 65 85.26 474 0.18 +-----GO:0017111 nucleoside-triphosphatase activity yeast 5.00E-10 0.000001 57 84.15 457 0.18 +------GO:0016887 ATPase activity yeast 1.00E-12 0.000000003 38 81.61 388 0.21 +-------GO:0042623 "ATPase activity, coupled " yeast 5.00E-16 1.00E-12 32 78.56 320 0.25 +--------GO:0043492 "ATPase activity, coupled to movement of substances " yeast 2.00E-24 4.00E-21 10 74.56 219 0.34 +--GO:0016788 "hydrolase activity, acting on ester bonds " +---GO:0004518 nuclease activity +----GO:0004527 exonuclease activity fly 0.0000006 0.001 9 61.63 213 0.29 +--GO:0008233 peptidase activity +---GO:0004175 endopeptidase activity +----GO:0004222 metalloendopeptidase activity fly 0.000005 0.009 11 37.11 117 0.32 +-GO:0016491 oxidoreductase activity +--GO:0016614 "oxidoreductase activity, acting on CH-OH group of donors " yeast 1.00E-10 0.0000002 11 47.68 191 0.25 +---GO:0016616 "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor " yeast 1.00E-10 0.0000002 11 47.68 191 0.25 +--GO:0016651 "oxidoreductase activity, acting on NADH or NADPH " fly 0.000007 0.014 7 2.28 100 0.02 +-GO:0016740 transferase activity worm 0.00001 0.006 60 149.57 1670 0.09 +--GO:0016741 "transferase activity, transferring one-carbon groups " fly 3.00E-11 0.00000005 29 22.44 419 0.05 +---GO:0008168 methyltransferase activity fly 3.00E-11 0.00000005 29 22.44 419 0.05 +----GO:0008757 S-adenosylmethionine-dependent methyltransferase activity fly 0.000000004 0.000007 24 21.05 366 0.06 +--GO:0016772 "transferase activity, transferring phosphorus-containing groups " worm 0.00000003 0.00002 45 120.53 1522 0.08 +---GO:0016301 kinase activity worm 0.00000003 0.00002 45 120.53 1522 0.08 +----GO:0004672 protein kinase activity worm 0.00000005 0.00003 38 118.75 1490 0.08 +-----GO:0004674 protein serine/threonine kinase activity worm 0.0000001 0.00008 12 56.23 831 0.07 +---GO:0016773 "phosphotransferase activity, alcohol group as acceptor " worm 0.00000002 0.00001 43 119.33 1515 0.08 +GO:0030234 enzyme regulator activity +-GO:0030695 GTPase regulator activity fly 2.00E-10 0.0000005 16 107.14 380 0.28 +--GO:0005085 guanyl-nucleotide exchange factor activity fly 0.000002 0.004 10 66.68 245 0.27 +GO:0060089 molecular transducer activity +-GO:0004871 signal transducer activity +--GO:0004872 receptor activity +---GO:0004888 transmembrane receptor activity +----GO:0004930 G-protein coupled receptor activity fly 0.00001 0.025 27 52.6 190 0.28 +-----GO:0001584 rhodopsin-like receptor activity fly 0.0000007 0.001 20 48.63 156 0.31 +GO:0005198 structural molecule activity yeast 0.000001 0.002 81 129.58 918 0.14 +-GO:0003735 structural constituent of ribosome fly 0.000002 0.004 37 18.07 280 0.06 +GO:0030528 transcription regulator activity yeast 0.000002 0.004 69 154.79 1152 0.13 +-GO:0003702 RNA polymerase II transcription factor activity yeast 2.00E-10 0.0000004 23 128.99 789 0.16 +--GO:0016251 general RNA polymerase II transcription factor activity yeast 3.00E-11 0.00000005 12 120.22 703 0.17 +GO:0005215 transporter activity yeast 0.000002 0.003 108 169.68 1280 0.13 +-GO:0005386 carrier activity yeast 3.00E-12 0.000000005 46 145.24 872 0.17 +--GO:0015399 primary active transporter activity yeast 2.00E-24 3.00E-21 12 75.2 223 0.34 +---GO:0015405 P-P-bond-hydrolysis-driven transporter activity yeast 2.00E-24 3.00E-21 12 75.2 223 0.34 +-GO:0015075 ion transporter activity yeast 7.00E-10 0.000001 36 90.71 505 0.18 +--GO:0008324 cation transporter activity yeast 6.00E-10 0.000001 30 89.73 495 0.18 +---GO:0015077 monovalent inorganic cation transporter activity yeast 3.00E-11 0.00000006 11 85.92 440 0.2 +----GO:0015078 hydrogen ion transporter activity yeast 3.00E-11 0.00000006 11 85.92 440 0.2 +-----GO:0046933 "hydrogen ion transporting ATP synthase activity, rotational mechanism " yeast 3.00E-12 0.000000005 5 84.46 414 0.2