atc	drugName	cui	event	# linkingProteins	uniprotIds_linkingProteins	drug_metabolite	p-val
M01AE03	ketoprofen	C0002871	anemia	3	[P10145, P02768, P07148]	DRUG	0.000832892
M01AB02	sulindac	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.028105805
C01BD01	amiodarone	C0003123	anorexia	1	[P28221]	METABOLITE	0.084655509
N06AX21	duloxetine	C0042024	urinary incontinence	4	[P08172, P28223, P21917, P29475]	DRUG	0.000266324
L01BC06	capecitabine	C0023798	lipoma	6	[P05177, P11509, P19971, P41231, P04818, P32320]	DRUG	0.150706133
N06AA01	desipramine	C0018790	cardiac arrest	3	[Q12809, P18089, P07550]	DRUG	0.003826662
S01ED03	levobunolol	C0015230	rash	2	[P07550, P08908]	DRUG	0.010306771
N06AX21	duloxetine	C0012833	dizziness	1	[P29274]	DRUG	0.04687583
N06AB08	fluvoxamine	C0149931	migraine	4	[P28223, P31645, P08684, P28335]	DRUG_AND_METABOLITE	5.37284E-05
P01AB01	metronidazole	C0018799	heart disease	1	[P11712]	DRUG	0.080618312
L01XE01	imatinib	C0035455	rhinitis	1	[P00533]	DRUG_AND_METABOLITE	0.383706376
G03HA01	cyproterone	C0020565	breast enlargement	1	[P11511]	DRUG	0.026275405
L04AX04	lenalidomide	C0684249	lung cancer	10	[P05181, P35354, P01375, P19838, P23219, P11712, P04798, P33261, P05177, P20815]	DRUG	2.25679E-05
C07AA03	pindolol	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG	0.002920249
N03AF01	carbamazepine	C0024299	lymphoma	2	[P08183, P35354]	METABOLITE	0.148596388
C03DB01	amiloride	C0012833	dizziness	1	[P29274]	DRUG	0.027308789
N06AX21	duloxetine	C0012813	diverticulitis	1	[P31645]	DRUG_AND_METABOLITE	0.135763824
M01AH02	rofecoxib	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.049477114
C10AA04	fluvastatin	C0024141	lupus	1	[P04798]	DRUG_AND_METABOLITE	0.187375311
D10AA02	methylprednisolone	C0011849	diabetes mellitus	2	[P08684, P10632]	DRUG_AND_METABOLITE	0.028343005
A05AA02	ursodeoxycholic acid	C0014868	esophagitis	1	[Q96RI1]	DRUG_AND_METABOLITE	0.026665834
R03DC01	zafirlukast	C0019158	hepatitis	2	[P05181, P23219]	DRUG_AND_METABOLITE	0.055850064
G04BE08	tadalafil	C0149931	migraine	1	[P08684]	DRUG	0.085994838
M01AH02	rofecoxib	C0009319	colitis	4	[P31645, P35354, P46098, P41595]	DRUG_AND_METABOLITE	0.023270062
N03AX11	topiramate	C0220981	metabolic acidosis	1	[Q16790]	DRUG	0.027162705
L04AX01	azathioprine	C0006826	cancer	12	[P17252, P06493, Q16539, P12931, O15440, P16220, P27361, Q13126, P15104, P22309, Q02750, P47989]	DRUG_AND_METABOLITE	0.422107082
N06BA09	atomoxetine	C0018799	heart disease	6	[Q12809, P31645, P08588, P07550, Q13639, P41595]	METABOLITE	0.011866315
J05AF03	zalcitabine	C0043144	wheezing	1	[P33527]	DRUG	0.33860389
R01AD01	beclomethasone	C0151514	skin atrophy	1	[P35354]	DRUG_AND_METABOLITE	0.256252122
N05AB06	trifluoperazine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.107647419
M01AE02	naproxen	C0018799	heart disease	6	[P23219, P31645, P35354, P11712, P33527, P41595]	DRUG	0.01524784
N05AB03	perphenazine	C0018790	cardiac arrest	1	[P18089]	DRUG	0.07705633
N02CC07	frovatriptan	C0027051	myocardial infarction	1	[P05177]	DRUG	0.101781344
C09AA01	captopril	C0027726	nephrotic syndrome	7	[P12821, Q9BYF1, P14780, P08253, P00797, P02768, P09211]	METABOLITE	0.000003054
C10AA02	lovastatin	C0151798	hepatic necrosis	4	[P09601, O95479, P08684, P05091]	METABOLITE	0.180499559
N06AA11	protriptyline	C0004134	ataxia	1	[P35498]	DRUG	0.17352585
N06BA04	methylphenidate	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	9.13424E-05
C10AX09	ezetimibe	C0008350	cholelithiasis	1	[P22309]	DRUG	0.025394378
P02CA01	mebendazole	C0015230	rash	1	[Q04864]	DRUG	0.100741343
C01BA01	quinidine	C0009951	convulsions	5	[P35498, P08183, Q99250, Q9NY46, P42262]	DRUG	0.004013885
J01AA02	doxycycline	C0085580	essential hypertension	2	[P08254, P08253]	DRUG	0.096811916
N01BB09	ropivacaine	C0003811	arrhythmia	2	[P22460, Q14524]	METABOLITE	0.003786357
A03FA02	cisapride	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.471662227
A02BC01	omeprazole	C0231528	myalgia	1	[Q8NER1]	DRUG	0.12340561
N02CC01	sumatriptan	C0014175	endometriosis	5	[P03372, Q92731, P14061, P56937, P04798]	METABOLITE	0.012309865
L01XE01	imatinib	C0027947	neutropenia	1	[P08183]	DRUG	0.322110519
C10AX09	ezetimibe	C0008325	cholecystitis	1	[P22309]	DRUG	0.023338897
N04BC04	ropinirole	C0004093	asthenia	1	[P28223]	DRUG	0.042475697
N04BC04	ropinirole	C0004096	asthma	1	[P07550]	DRUG	0.326920196
N06AA01	desipramine	C0018681	headache	1	[P05362]	DRUG	0.093555819
N01AH01	fentanyl	C0015672	fatigue	1	[P28223]	DRUG	0.030655726
G04BE03	sildenafil	C0242184	hypoxia	2	[Q14432, Q12809]	DRUG	0.198870554
G04BE07	apomorphine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.005170758
N05AB06	trifluoperazine	C0013595	eczema	6	[P07550, P28223, P08908, P31645, P17405, P04629]	DRUG	0.042612664
N05AE04	ziprasidone	C0020473	hyperlipidemia	1	[P07550]	DRUG	0.226030864
N05AG02	pimozide	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.00054791
N06AB05	paroxetine	C1510472	drug dependence	1	[P41595]	DRUG	0.028123725
C07AA06	timolol	C0015672	fatigue	1	[P28223]	DRUG	0.024401265
N02CC01	sumatriptan	C0231528	myalgia	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.169250637
N06AX21	duloxetine	C0042109	urticaria	2	[P07550, P09917]	METABOLITE	0.036308188
M01AE02	naproxen	C0037763	spasm	2	[P14867, P21918]	DRUG	0.010207101
N06AB04	citalopram	C0442874	neuropathy	1	[P08183]	DRUG	0.114516617
C08DA01	verapamil	C0021311	infection	1	[Q13936]	DRUG_AND_METABOLITE	0.497837942
N06BA01	amphetamine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.016169699
N06AB08	fluvoxamine	C0011849	diabetes mellitus	2	[P11712, P08684]	DRUG_AND_METABOLITE	0.120202358
N05BE01	buspirone	C0242422	Parkinson	11	[P21917, Q01959, P32238, P08183, P21554, P50406, P08908, P31645, Q9UQD0, P14416, P35462]	DRUG_AND_METABOLITE	4.51738E-06
N02CC01	sumatriptan	C0018524	hallucinations	1	[P08183]	DRUG_AND_METABOLITE	0.169250637
L01XE02	gefitinib	C0032285	pneumonia	2	[P43405, P20783]	DRUG_AND_METABOLITE	0.333990256
N06BA09	atomoxetine	C0018681	headache	1	[P29475]	DRUG	0.080576655
L01XE01	imatinib	C0206061	interstitial pneumonitis	2	[P43405, P20783]	DRUG	0.28280781
N04BC04	ropinirole	C0027651	tumor	5	[P08684, P05177, Q13639, P35348, P07550]	DRUG	0.499995859
R03DC01	zafirlukast	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.128824251
N06AB05	paroxetine	C0027051	myocardial infarction	4	[P11712, P31645, P08588, P18089]	DRUG	0.050945221
N06AA04	clomipramine	C0085584	encephalopathy	4	[P14867, P35372, P04156, P08183]	DRUG_AND_METABOLITE	0.012792437
N06AA04	clomipramine	C0085583	choreoathetosis	1	[Q12791]	METABOLITE	0.086098006
A16AA04	cysteamine	C0020538	hypertension	13	[P35348, P07550, P21728, P37288, P48506, P31645, Q9Y2I1, P28223, P23975, P32929, P08913, P18089, P08588]	METABOLITE	6.31065E-05
L02BA01	tamoxifen	C0019080	hemorrhage	1	[P11712]	DRUG	0.103034195
L04AX04	lenalidomide	C0015672	fatigue	1	[P35354]	DRUG	0.034147949
N03AX16	pregabalin	C0497327	dementia	2	[P80404, O00555]	DRUG	0.021357772
N06BA04	methylphenidate	C0009951	convulsions	2	[P08908, P31645]	DRUG_AND_METABOLITE	0.094719012
A02BC03	lansoprazole	C0002874	aplastic anemia	1	[P04798]	DRUG	0.128073342
N06AA02	imipramine	C0015230	rash	6	[P07550, P28223, P08908, P31645, P17405, P09211]	DRUG	0.035812138
A02BC03	lansoprazole	C0699893	skin carcinoma	2	[Q9UNQ0, P04798]	DRUG	0.31283312
L01XE02	gefitinib	C0032273	pneumoconiosis	3	[P04626, P20783, Q05655]	DRUG_AND_METABOLITE	0.193404979
N06AA04	clomipramine	C0006266	bronchospasm	8	[P07550, P09211, P43115, P29475, P11229, P29274, P20309, Q14643]	METABOLITE	0.051748375
N04BD01	selegiline	C0006325	bruxism	1	[P31645]	METABOLITE	0.020240076
A02BC04	rabeprazole	C0009324	ulcerative colitis	2	[P08183, P35354]	DRUG	0.129936284
A02BC04	rabeprazole	C0009319	colitis	2	[P08183, P35354]	DRUG	0.140962442
C01BC03	propafenone	C0085615	bundle branch block right	1	[Q14524]	DRUG	0.005809415
C01BC03	propafenone	C0085610	sinus bradycardia	1	[Q14524]	DRUG	0.012792437
N06AB03	fluoxetine	C0030305	pancreatitis	1	[P05181]	DRUG	0.243722775
A07EA06	budesonide	C0699744	ear infection	5	[P35228, P05113, P35354, P23219, P09917]	METABOLITE	0.07862137
R06AX27	desloratadine	C0020517	hypersensitivity	2	[P35367, Q9H3N8]	DRUG	0.005067088
N05AE04	ziprasidone	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.001081481
A04AA01	ondansetron	C0027051	myocardial infarction	4	[P07550, P11712, P05177, P08588]	DRUG	0.190102925
A11CC04	calcitriol	C0027709	nephrocalcinosis	1	[P11473]	DRUG_AND_METABOLITE	0.008782102
G03DA04	progesterone	C0027651	tumor	41	[Q9UNQ0, P04798, Q16678, P11511, P08684, P03372, Q15788, P08183, P06401, P19793, Q92731, P04278, O75469, P15531, P33527, Q99720, P52895, Q04828, P08235, O00591, P14061, Q96RI1, P05093, P46721, P05108, P05181, P05177, P10275, P20813, P04150, P20815, P10632, P18405, P35610, P11509, P31213, Q9HB55, P37058, O75751, P33261, P35348]	METABOLITE	0.139972834
J02AC01	fluconazole	C0019080	hemorrhage	1	[P11712]	DRUG	0.045012311
J01MA07	lomefloxacin	C0151798	hepatic necrosis	1	[Q92887]	DRUG	0.089912296
G03AC06	medroxyprogesterone	C0041912	upper respiratory tract infection	1	[P03372]	DRUG_AND_METABOLITE	0.265710033
N05AE04	ziprasidone	C0020550	hyperthyroidism	1	[P07550]	DRUG	0.171851017
N06AB04	citalopram	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.165492261
N05AE04	ziprasidone	C0020538	hypertension	11	[P20815, P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG	0.000139685
C07AA12	nadolol	C0006266	bronchospasm	1	[P07550]	DRUG	0.105539171
L02AB01	megestrol	C0020538	hypertension	3	[P03372, P11712, P04150]	DRUG	0.0055472
N03AX11	topiramate	C0014549	grand mal	2	[Q99250, P35498]	DRUG	0.004954116
N06AA01	desipramine	C0018524	hallucinations	5	[P08183, P35498, Q99250, P04156, Q9NY46]	DRUG	0.00081817
C07AA12	nadolol	C0018801	heart failure	1	[P07550]	DRUG	0.040601904
L04AX04	lenalidomide	C0027051	myocardial infarction	9	[P35354, P01375, Q08499, P04798, O14788, P11712, P33261, P23219, P05177]	DRUG	8.11219E-07
C09AA07	benazepril	C0002962	angina pectoris	1	[P42898]	DRUG	0.022436068
C09AA07	benazepril	C0015672	fatigue	1	[P12821]	DRUG_AND_METABOLITE	0.012425662
P01AX06	atovaquone	C0012833	dizziness	1	[P29274]	METABOLITE	0.054359067
G03HA01	cyproterone	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.03976834
C09CA01	losartan	C0022346	jaundice	1	[P22309]	DRUG	0.025953097
L01XE01	imatinib	C0023530	leukopenia	1	[P08183]	DRUG	0.372290424
N06AB04	citalopram	C0020517	hypersensitivity	2	[Q01959, P35367]	DRUG	0.018703451
N05BA01	diazepam	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.001450138
N05CA06	secobarbital	C0004134	ataxia	1	[P35498]	DRUG	0.069093062
N06AB04	citalopram	C0020538	hypertension	7	[P35348, P21728, P31645, P28223, P23975, P08913, P08588]	DRUG	0.000227335
L02BA02	toremifene	C0086543	cataract	2	[P09488, P30711]	METABOLITE	0.039536739
C07AA05	propranolol	C0001824	agranulocytosis	1	[P08183]	DRUG	0.083416405
L01XE01	imatinib	C0027720	nephrosis	2	[P02768, P15056]	DRUG	0.324188139
N04BC05	pramipexole	C0009324	ulcerative colitis	1	[P31645]	DRUG	0.283690142
A07EC01	sulfasalazine	C0042109	urticaria	1	[P09917]	DRUG_AND_METABOLITE	0.063596471
N04BC05	pramipexole	C0009319	colitis	3	[P31645, P46098, P41595]	DRUG	0.0464334
J05AF04	stavudine	C0011849	diabetes mellitus	3	[P11712, P02768, P10632]	METABOLITE	0.060597648
M01AE02	naproxen	C0008031	chest pain	1	[P02768]	DRUG	0.034021738
L02BA01	tamoxifen	C0231528	myalgia	1	[P17252]	METABOLITE	0.145989685
N04BC04	ropinirole	C0497327	dementia	1	[P08908]	DRUG	0.244209776
N05AC02	thioridazine	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.058255985
M03BX08	cyclobenzaprine	C1527304	allergic reaction	6	[P41595, Q8NER1, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	4.1541E-05
G04BD04	oxybutynin	C0149931	migraine	1	[P08684]	DRUG	0.043989678
D07AC04	fluocinolone acetonide	C0011849	diabetes mellitus	1	[P47712]	DRUG	0.077274451
C09CA04	irbesartan	C0027121	myositis	1	[P23219]	DRUG_AND_METABOLITE	0.057987175
N06AB08	fluvoxamine	C0009319	colitis	2	[P08183, P31645]	DRUG_AND_METABOLITE	0.061427537
C07AB03	atenolol	C0011570	mental depression	4	[P28223, P28335, P28222, P08908]	DRUG	6.31966E-06
M01AC06	meloxicam	C0017152	gastritis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.002812013
C09CA07	telmisartan	C0007820	cerebrovascular disorder	2	[P30556, P37231]	DRUG	0.032735559
N02AA03	hydromorphone	C0007097	carcinoma	8	[P08183, P23219, P21964, P20815, P10632, P08684, Q12809, P23975]	METABOLITE	0.378588181
H02AA02	fludrocortisone	C0020538	hypertension	4	[P05026, P05023, P08235, P04150]	DRUG_AND_METABOLITE	0.002069577
L04AA13	leflunomide	C0024115	lung disorder	3	[P35869, P03956, P05177]	DRUG	0.010335988
G03CA03	estradiol	C0014544	epilepsy	5	[P08183, P35498, Q99250, P33527, Q9NY46]	DRUG	0.002922873
A10BG03	pioglitazone	C0038454	cerebrovascular accident	1	[P37231]	DRUG_AND_METABOLITE	0.172037281
N05AE04	ziprasidone	C0020615	hypoglycemia	1	[P07550]	DRUG	0.13838486
C07AB02	metoprolol	C0007820	cerebrovascular disorder	1	[P07550]	DRUG_AND_METABOLITE	0.153954947
N06BA09	atomoxetine	C0699744	ear infection	2	[P07550, P17252]	DRUG	0.466568367
S01ED04	metipranolol	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.008782102
N05BC01	meprobamate	C0006266	bronchospasm	11	[P07550, P50135, P09211, P48506, P29508, P01024, P42898, P11229, P29274, P20309, P12931]	METABOLITE	0.019059388
N04BC02	pergolide	C0009806	constipation	1	[P41595]	DRUG_AND_METABOLITE	0.037128649
N06AB04	citalopram	C0042024	urinary incontinence	1	[P28223]	DRUG	0.048951084
A04AA02	granisetron	C0149931	migraine	3	[P28223, P08684, P28335]	DRUG_AND_METABOLITE	0.000821544
L04AX02	thalidomide	C0014175	endometriosis	4	[P01375, P21802, P35354, P04798]	DRUG	0.167589687
L04AX02	thalidomide	C0014130	Endocrine Disorders	3	[P35354, P23219, P04798]	DRUG	0.292773007
G04BE09	vardenafil	C0030193	pain	1	[Q08499]	DRUG	0.03201379
G03DA04	progesterone	C0015230	rash	2	[P28223, P08908]	METABOLITE	0.27973647
N04BC04	ropinirole	C0027430	nasal polyps	1	[P05177]	DRUG	0.499995859
H02AB02	dexamethasone	C0017601	glaucoma	2	[Q16678, P04150]	DRUG_AND_METABOLITE	0.018943768
N06AX21	duloxetine	C0231218	malaise	1	[Q8NER1]	DRUG	0.04687583
M01AE02	naproxen	C0018834	heartburn	1	[P23219]	DRUG	0.056713506
N06AA06	trimipramine	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.187583024
N01AH01	fentanyl	C0011570	mental depression	4	[P08684, P28223, P28335, P21397]	DRUG	2.08794E-05
G03BA03	testosterone	C0018799	heart disease	8	[Q99527, P04278, P03372, P12104, Q92731, P11712, P19793, P20813]	DRUG_AND_METABOLITE	0.008514022
J02AC02	itraconazole	C0024117	COPD	2	[P05181, P04798]	DRUG_AND_METABOLITE	0.02641158
L02BG06	exemestane	C0020538	hypertension	1	[P11511]	DRUG	0.119954952
M01AE02	naproxen	C0018802	congestive heart failure	1	[Q9Y2I1]	DRUG	0.214459208
M01AE02	naproxen	C0018801	heart failure	1	[Q9Y2I1]	DRUG	0.214459208
A02BC03	lansoprazole	C1527304	allergic reaction	1	[P25021]	DRUG_AND_METABOLITE	0.079709923
C09AA06	quinapril	C0015672	fatigue	1	[P12821]	DRUG_AND_METABOLITE	0.010207101
C09CA04	irbesartan	C0027051	myocardial infarction	4	[P30556, P11712, P23219, P05177]	DRUG_AND_METABOLITE	0.003094049
A02BC01	omeprazole	C0231218	malaise	1	[Q8NER1]	DRUG	0.021299045
N06BC01	caffeine	C0019080	hemorrhage	2	[P00813, P11712]	DRUG_AND_METABOLITE	0.026888854
L01XX11	estramustine	C0023530	leukopenia	2	[P22309, P08183]	DRUG_AND_METABOLITE	0.020093213
A10BB09	gliclazide	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.019239124
J01MA01	ofloxacin	C0035078	renal failure	1	[P08183]	DRUG	0.086440059
L01XE03	erlotinib	C0206061	interstitial pneumonitis	2	[P43405, P20783]	DRUG_AND_METABOLITE	0.258243924
L01XE03	erlotinib	C0206062	interstitial lung disease	1	[P20783]	DRUG_AND_METABOLITE	0.135133707
C09CA01	losartan	C0002878	hemolytic anemia	1	[P22309]	DRUG	0.070518569
M01AE03	ketoprofen	C0011849	diabetes mellitus	6	[P15121, P11712, P10145, P35354, P02768, P10632]	DRUG	0.000153802
G03CA03	estradiol	C0019158	hepatitis	2	[P05181, P02768]	DRUG_AND_METABOLITE	0.090072836
C03BA11	indapamide	C0007097	carcinoma	3	[Q16790, P51452, O43570]	DRUG_AND_METABOLITE	0.4619044
C09AA02	enalapril	C0013404	dyspnea	1	[P12821]	DRUG_AND_METABOLITE	0.032699237
N04BX01	tolcapone	C0011849	diabetes mellitus	1	[P11712]	DRUG	0.20086833
N06AB04	citalopram	C1456784	paranoia	1	[P05177]	DRUG	0.023338897
N03AX16	pregabalin	C0004134	ataxia	3	[P80404, O00555, Q9NY47]	DRUG	9.13424E-05
N04BC05	pramipexole	C0039239	sinus tachycardia	2	[P07550, P08588]	DRUG	0.002795416
N04BC05	pramipexole	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.002795416
N06AX06	nefazodone	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.048595777
N03AA03	primidone	C0003123	anorexia	1	[P14416]	METABOLITE	0.122499116
C01BB02	mexiletine	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG_AND_METABOLITE	9.70269E-05
C01BA01	quinidine	C0024141	lupus	2	[P04798, Q92887]	DRUG	0.212234884
N06AB03	fluoxetine	C0037763	spasm	1	[P21918]	DRUG	0.065962289
N06AX16	venlafaxine	C0149931	migraine	6	[P29475, P28223, P31645, P35498, P08684, P28335]	DRUG_AND_METABOLITE	3.52831E-05
L01DB06	idarubicin	C0018799	heart disease	2	[P11712, P33527]	DRUG	0.010207101
N05AH04	quetiapine	C0023530	leukopenia	1	[P08183]	DRUG	0.14059695
N03AX11	topiramate	C0018524	hallucinations	2	[P35498, Q99250]	DRUG	0.015294093
N02CC01	sumatriptan	C0006266	bronchospasm	2	[P07550, O94956]	METABOLITE	0.27121873
L04AX04	lenalidomide	C0027651	tumor	13	[P04798, P21802, P35354, P01375, P19838, P33151, O14788, P05181, P05177, P20815, P23219, Q08499, P33261]	DRUG	0.016368485
L04AX04	lenalidomide	C0006826	cancer	10	[P35354, P19838, P01375, P21802, O14788, P20815, P05181, P04798, P23219, P05177]	DRUG	0.010731647
N01AH01	fentanyl	C0023530	leukopenia	1	[P08183]	DRUG	0.057691049
M01AH01	celecoxib	C0006266	bronchospasm	4	[P09917, P35354, P23219, P33527]	DRUG	0.100645764
M01AE02	naproxen	C0021400	Influenza	1	[P60953]	DRUG	0.134277285
N04BC04	ropinirole	C0027932	neurosis	2	[P28223, P14416]	DRUG_AND_METABOLITE	0.00183769
N01AH01	fentanyl	C0015230	rash	1	[P28223]	DRUG	0.153852185
N03AF01	carbamazepine	C0013395	Dyspepsia	1	[P23219]	METABOLITE	0.035695087
N03AF01	carbamazepine	C0013384	dyskinesia	2	[P35498, P14416]	DRUG	0.019239124
C07AB03	atenolol	C0033975	psychosis	3	[P28223, P28222, P08908]	DRUG	0.000425881
M01AH01	celecoxib	C0027051	myocardial infarction	7	[P35354, P21554, P11712, P31645, P07451, P23219, P18089]	DRUG	0.017306495
G03AC06	medroxyprogesterone	C0178421	fibroadenoma of breast	7	[P08684, P03372, P08183, P06401, P08235, P10275, P04150]	DRUG_AND_METABOLITE	0.001335062
R06AD02	promethazine	C0013604	edema	1	[P08588]	DRUG	0.049976501
C09CA06	candesartan	C0035078	renal failure	2	[P30556, P08183]	DRUG_AND_METABOLITE	0.004513173
N06AB04	citalopram	C0012813	diverticulitis	1	[P31645]	DRUG	0.055548179
N02CC06	eletriptan	C0021311	infection	1	[P23219]	DRUG	0.338647638
C01EB03	indomethacin	C0007097	carcinoma	19	[P35354, P08183, P10828, Q92887, P33527, P10145, P23219, P35408, P34995, O95255, P09917, P37231, P25101, O15438, P42330, P43116, P22309, P41222, P14550]	DRUG	0.059078532
C08DB01	diltiazem	C0041912	upper respiratory tract infection	1	[Q13936]	DRUG	0.443762378
C01BC03	propafenone	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.042804682
N05AH02	clozapine	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG_AND_METABOLITE	0.001965274
A07EA06	budesonide	C0019080	hemorrhage	1	[P11712]	METABOLITE	0.098229155
R06AE07	cetirizine	C0018801	heart failure	1	[Q12809]	DRUG	0.035667691
C03DB01	amiloride	C0020517	hypersensitivity	3	[O75762, P19801, P35367]	DRUG	0.006229806
G04BE08	tadalafil	C0231528	myalgia	1	[Q08499]	DRUG	0.107464244
M01AC06	meloxicam	C0009319	colitis	1	[P35354]	DRUG_AND_METABOLITE	0.10492878
R03DC03	montelukast	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.016701405
M01AH03	valdecoxib	C0041912	upper respiratory tract infection	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.455180546
N06DX01	memantine	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.043796069
G04BE09	vardenafil	C0231528	myalgia	1	[Q08499]	DRUG	0.107464244
C07AA06	timolol	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.003425546
G03DA04	progesterone	C0002871	anemia	3	[P11413, P02768, P07148]	DRUG_AND_METABOLITE	0.029823411
D11AX10	finasteride	C0006826	cancer	5	[P20815, P18405, P08684, P10275, P31213]	DRUG_AND_METABOLITE	0.076302208
L01XE01	imatinib	C0020517	hypersensitivity	2	[P00533, O60674]	DRUG	0.288980973
N03AX11	topiramate	C0027651	tumor	5	[P08684, Q16790, Q99720, O43570, P33261]	DRUG	0.461170573
P01AB01	metronidazole	C0006826	cancer	2	[P10632, P08684]	DRUG	0.129904415
G03CA03	estradiol	C0086692	benign tumors	20	[P05177, P32238, P08183, P03372, Q92887, Q92731, P33527, P08842, Q9UNQ0, P32239, P20815, P05181, Q16678, P50225, P22309, P04798, P10275, P21964, P11474, O15438]	DRUG	0.042794949
A07EC01	sulfasalazine	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.035695087
C09CA06	candesartan	C0011849	diabetes mellitus	4	[P11712, O15245, P30556, P10632]	DRUG_AND_METABOLITE	0.0007492
L01XE01	imatinib	C0020538	hypertension	12	[P20815, P31749, P06213, P08922, P37173, Q13873, O15244, P11712, P36897, Q14289, P37023, P12931]	DRUG_AND_METABOLITE	0.219072317
C09CA01	losartan	C0239377	arm pain	1	[Q08499]	DRUG	0.019028106
J01AA08	minocycline	C0042384	vasculitis	1	[P01584]	DRUG	0.056270313
L01XE01	imatinib	C0020565	breast enlargement	2	[P49841, P31749]	DRUG	0.307145519
N05AE04	ziprasidone	C0042109	urticaria	1	[P07550]	DRUG	0.105679533
D07AC04	fluocinolone acetonide	C0011603	dermatitis	1	[P47712]	DRUG	0.064272968
J05AG03	efavirenz	C0020538	hypertension	1	[P11712]	DRUG	0.169593997
L01DB06	idarubicin	C0023418	leukemia	1	[P11388]	DRUG	0.147022778
A02BC01	omeprazole	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.050501715
C10AA01	simvastatin	C0041912	upper respiratory tract infection	1	[P05107]	DRUG_AND_METABOLITE	0.321652191
L02BB03	bicalutamide	C0027651	tumor	5	[P08684, P03372, P06401, P10275, P04150]	DRUG	0.013699578
N04BX01	tolcapone	C1458155	breast neoplasm	3	[P21964, P06493, P27487]	METABOLITE	0.347570229
N05AX12	aripiprazole	C0497327	dementia	4	[P08908, P31645, P17787, P43681]	METABOLITE	0.043339606
N05AH03	olanzapine	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG	9.71969E-06
C01EB03	indomethacin	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.050504261
M01AE02	naproxen	C0021311	infection	3	[P35354, P23219, P09917]	DRUG	0.439653197
G02CB01	bromocriptine	C0005747	blepharospasm	2	[P21918, P14416]	DRUG_AND_METABOLITE	0.023287347
N03AF01	carbamazepine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.070518569
C03DB01	amiloride	C0020456	hyperglycemia	1	[Q9Y210]	DRUG	0.146540748
C09AA10	trandolapril	C0033860	psoriasis	1	[P12821]	DRUG_AND_METABOLITE	0.055755321
J01MA02	ciprofloxacin	C0001824	agranulocytosis	1	[P08183]	DRUG	0.044574807
N06AB03	fluoxetine	C0030794	pelvic pain	1	[Q08499]	METABOLITE	0.045375219
C09CA06	candesartan	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.039009407
J02AC02	itraconazole	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.026275405
L04AX04	lenalidomide	C0015230	rash	1	[P01375]	DRUG	0.171578823
M01AE01	ibuprofen	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000536558
C10AB04	gemfibrozil	C0026848	myopathy	1	[Q9Y6L6]	DRUG	0.078232634
J01FA09	clarithromycin	C0001175	acquired immunodeficiency syndrome	2	[P20815, P08684]	DRUG_AND_METABOLITE	0.03325801
G03CA03	estradiol	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.171867333
A02BC02	pantoprazole	C1527304	allergic reaction	1	[P25021]	METABOLITE	0.081682023
M01AE02	naproxen	C0021390	inflammatory bowel disease	2	[P09917, P31645]	DRUG	0.145448571
L04AX04	lenalidomide	C0019348	herpes simplex	1	[P19838]	DRUG	0.089658424
N05BE01	buspirone	C0019080	hemorrhage	1	[P21731]	METABOLITE	0.153150776
N03AX11	topiramate	C0011570	mental depression	2	[P33261, P08684]	DRUG	0.010218075
N04BC04	ropinirole	C0004153	atherosclerotic vascular disease	1	[P08684]	DRUG	0.310507336
D06AA01	demeclocycline	C0002792	anaphylaxis	1	[P08253]	DRUG	0.056501401
J05AF03	zalcitabine	C0027121	myositis	1	[P61073]	DRUG	0.105539171
N04BD01	selegiline	C0018524	hallucinations	1	[P08183]	DRUG	0.153492368
N01BB09	ropivacaine	C0021311	infection	2	[P00533, Q13936]	METABOLITE	0.344347567
N06AB08	fluvoxamine	C0009806	constipation	1	[P31645]	DRUG_AND_METABOLITE	0.033221489
N06AB05	paroxetine	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.03201379
C01BB02	mexiletine	C0015230	rash	5	[P00749, P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.016169699
C09AA02	enalapril	C0013604	edema	1	[P00797]	METABOLITE	0.02023865
A04AA01	ondansetron	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.00621496
M01AH01	celecoxib	C1527304	allergic reaction	4	[P41595, Q01959, P35367, P25021]	DRUG	0.000629183
C09AA03	lisinopril	C0020615	hypoglycemia	1	[P12821]	DRUG	0.022963468
R03AC12	salmeterol	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.00015919
A02BC04	rabeprazole	C0027947	neutropenia	1	[P08183]	METABOLITE	0.09523719
G03BA03	testosterone	C0018418	gynecomastia	1	[P11511]	DRUG_AND_METABOLITE	0.032885129
N05AA01	chlorpromazine	C1527304	allergic reaction	7	[P41595, Q8NER1, Q01959, P29475, P35367, P25021, Q9H3N8]	DRUG	3.62975E-05
N05AB02	fluphenazine	C0018790	cardiac arrest	1	[P18089]	DRUG	0.084819498
N04BC04	ropinirole	C1458155	breast neoplasm	2	[P08684, P05177]	DRUG	0.499995859
L02BB03	bicalutamide	C0004093	asthenia	1	[P04150]	DRUG	0.014253709
L02BB03	bicalutamide	C0004096	asthma	1	[P04150]	DRUG	0.105539171
C03DA04	eplerenone	C0033687	proteinuria	1	[P08235]	DRUG	0.032885129
C10AB05	fenofibrate	C0023530	leukopenia	1	[P08246]	DRUG	0.046530938
N05AC02	thioridazine	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG_AND_METABOLITE	0.001081481
C09AA13	moexipril	C0006266	bronchospasm	1	[P12821]	DRUG_AND_METABOLITE	0.105539171
N02AA03	hydromorphone	C0037763	spasm	1	[P21918]	METABOLITE	0.052191974
N05CF02	zolpidem	C0086769	panic attacks	1	[P30536]	DRUG_AND_METABOLITE	0.061166635
J01FF01	clindamycin	C0162323	polyarthritis	1	[Q9UM07]	DRUG_AND_METABOLITE	0.035524195
A03FA02	cisapride	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.006793653
M01AE01	ibuprofen	C0009951	convulsions	5	[P08183, P33527, P08908, P31645, P35354]	DRUG	0.019646445
S01AA14	penicillin G	C0042109	urticaria	1	[P12319]	DRUG	0.092356341
N05AB04	prochlorperazine	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.016701405
M01AE02	naproxen	C0018524	hallucinations	1	[P33527]	DRUG	0.201694851
N02CC01	sumatriptan	C0018944	hematoma	1	[P11712]	METABOLITE	0.110503219
N05CA01	pentobarbital	C0020517	hypersensitivity	1	[P35367]	DRUG	0.137464625
N04BC02	pergolide	C0014130	Endocrine Disorders	1	[Q13639]	DRUG	0.271879838
C01BC03	propafenone	C0018802	congestive heart failure	2	[Q14524, Q12809]	DRUG_AND_METABOLITE	0.010731647
C10AA04	fluvastatin	C0003864	arthritis	1	[P27487]	DRUG_AND_METABOLITE	0.10214274
J05AF05	lamivudine	C0149931	migraine	1	[P08684]	DRUG	0.067555547
N05BE01	buspirone	C0023530	leukopenia	1	[P08183]	DRUG	0.149189442
N06AA10	nortriptyline	C0004134	ataxia	1	[P35498]	DRUG	0.17352585
M01AH02	rofecoxib	C0013295	duodenal ulcer	1	[P35354]	DRUG_AND_METABOLITE	0.093159412
R03DC03	montelukast	C0013595	eczema	1	[Q9Y271]	DRUG_AND_METABOLITE	0.096195732
G03BA03	testosterone	C0010054	coronary artery disease	7	[P08684, P02768, P03372, P04798, P10275, P04278, Q92731]	METABOLITE	0.014494106
M01AE01	ibuprofen	C0017168	gastroesophageal reflux	5	[P25025, P10145, P25024, P33261, O00519]	DRUG	1.54047E-05
N04BC05	pramipexole	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.481136401
N02CC06	eletriptan	C0004096	asthma	1	[P23219]	DRUG	0.210510758
N05CD04	estazolam	C0037763	spasm	3	[P18507, P14867, P28472]	DRUG	2.82724E-05
J05AE03	ritonavir	C0030305	pancreatitis	1	[P05181]	DRUG	0.12507432
N02AA03	hydromorphone	C0162297	respiratory arrest	1	[Q9UQD0]	DRUG_AND_METABOLITE	0.069031215
L01CB01	etoposide	C0015230	rash	1	[P42574]	DRUG_AND_METABOLITE	0.17748583
N05CD02	nitrazepam	C0015672	fatigue	3	[P31645, P28223, P35354]	DRUG	0.000588768
A07AA11	rifaximin	C0149931	migraine	1	[P08684]	DRUG	0.037810863
C01BB01	lidocaine	C0042510	ventricular fibrillation	1	[Q14524]	DRUG	0.017783546
M01AE01	ibuprofen	C0017152	gastritis	3	[P10145, P23219, P35354]	DRUG	0.014259954
C07AG02	carvedilol	C1565489	renal insufficiency	1	[P16860]	DRUG	0.040204533
N02CC01	sumatriptan	C0018799	heart disease	8	[P08588, P03372, Q92731, P11712, P07550, P20813, Q13639, P41595]	DRUG	0.000356248
C07AA05	propranolol	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.075667737
R03DC03	montelukast	C0041912	upper respiratory tract infection	2	[P23219, P09917]	DRUG_AND_METABOLITE	0.085415282
C01BC03	propafenone	C0018790	cardiac arrest	2	[Q14524, Q12809]	DRUG_AND_METABOLITE	0.002505476
N06AB03	fluoxetine	C0030920	peptic ulcer	1	[P33261]	DRUG	0.131507778
C04AD03	pentoxifylline	C0020538	hypertension	3	[Q08499, P01375, P29275]	DRUG	0.016167337
A02BC04	rabeprazole	C0033860	psoriasis	1	[P04798]	DRUG_AND_METABOLITE	0.285107447
M01AE01	ibuprofen	C0002878	hemolytic anemia	1	[P22309]	DRUG	0.153324068
M01AE01	ibuprofen	C0002871	anemia	3	[P10145, P02768, P07148]	DRUG	0.022280235
J01AA08	minocycline	C0042109	urticaria	1	[P09917]	DRUG	0.054232974
N06AB04	citalopram	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.033737522
N05AB06	trifluoperazine	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.206353335
R06AD02	promethazine	C0013384	dyskinesia	4	[P35498, P14416, P21917, P35462]	DRUG	0.000567253
G03BA03	testosterone	C0002871	anemia	2	[P11413, P02768]	DRUG_AND_METABOLITE	0.082415968
N05AA01	chlorpromazine	C0040822	tremor	1	[Q14643]	DRUG	0.080976776
C07AG01	labetalol	C0043144	wheezing	1	[P07550]	DRUG	0.179324562
N05AC02	thioridazine	C0042109	urticaria	1	[P07550]	DRUG	0.105679533
N05AH04	quetiapine	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.097563145
C01BA02	procainamide	C0003123	anorexia	1	[P14416]	DRUG	0.063596471
C09CA06	candesartan	C0039231	tachycardia	1	[P30556]	DRUG_AND_METABOLITE	0.016701405
C09AA10	trandolapril	C0004093	asthenia	1	[P12821]	DRUG_AND_METABOLITE	0.012425662
C04AD03	pentoxifylline	C0020517	hypersensitivity	1	[P01375]	DRUG_AND_METABOLITE	0.06174012
C01EB03	indomethacin	C0021311	infection	6	[P10145, P35354, P23219, P37231, P09917, Q04760]	DRUG	0.123908164
N04BD01	selegiline	C0152032	urinary hesitancy	1	[Q16853]	DRUG_AND_METABOLITE	0.194915631
M01AE02	naproxen	C0008350	cholelithiasis	1	[P22309]	DRUG	0.103034195
C10AB05	fenofibrate	C0149931	migraine	1	[P08684]	DRUG	0.052242123
J01XE01	nitrofurantoin	C0016059	fibrosis	1	[P05181]	DRUG	0.051022002
V03AH01	diazoxide	C0027051	myocardial infarction	5	[P13945, P07550, O60706, P08588, Q12791]	DRUG	0.000536558
G03DA04	progesterone	C0015672	fatigue	3	[P08185, P28223, P04150]	DRUG_AND_METABOLITE	0.001365729
L04AX04	lenalidomide	C0043144	wheezing	4	[P01375, P35354, P23219, Q08499]	DRUG	0.009329478
A03BA01	atropine	C0015672	fatigue	1	[P28223]	DRUG	0.042475697
M01AE02	naproxen	C0008325	cholecystitis	1	[P22309]	DRUG	0.095603741
M01AB08	etodolac	C0009951	convulsions	1	[P35354]	DRUG_AND_METABOLITE	0.121820026
N06AB08	fluvoxamine	C0039231	tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.030408848
A07DA03	loperamide	C0018681	headache	1	[O00555]	DRUG	0.045415082
A02BA01	cimetidine	C0030305	pancreatitis	1	[P05181]	DRUG	0.206679872
L02BA02	toremifene	C0004093	asthenia	1	[P35354]	METABOLITE	0.081756348
C01EB03	indomethacin	C0019080	hemorrhage	2	[P24557, P11712]	DRUG	0.027408834
N06AX11	mirtazapine	C0020538	hypertension	8	[P35348, P21728, P31645, P28223, P11712, P23975, P08913, P18089]	DRUG	0.000195869
N05AH04	quetiapine	C0027947	neutropenia	1	[P08183]	DRUG	0.115784639
N06AA12	doxepin	C0013595	eczema	6	[P07550, P28223, P08908, P31645, P17405, P04629]	DRUG	0.02342572
N06AX11	mirtazapine	C0029456	osteoporosis	1	[P08684]	DRUG	0.178569817
A08AA10	sibutramine	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.023247987
C03DA01	spironolactone	C0035078	renal failure	1	[P08183]	DRUG	0.083870425
L04AX02	thalidomide	C0009812	constitutional symptoms	1	[P01375]	DRUG	0.058400414
A08AA10	sibutramine	C0003123	anorexia	6	[P28223, P21917, P28335, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
N05AH02	clozapine	C0020517	hypersensitivity	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	0.000723628
M01AE01	ibuprofen	C0042109	urticaria	1	[P09917]	DRUG	0.122499116
N03AB02	phenytoin	C0004134	ataxia	1	[P35498]	DRUG_AND_METABOLITE	0.125551671
N06AX16	venlafaxine	C0013384	dyskinesia	5	[Q14643, P35498, Q12791, P14416, P35462]	DRUG_AND_METABOLITE	0.000486368
N05AH02	clozapine	C0020538	hypertension	13	[P35348, P13945, P07550, P21728, P31645, Q9Y2I1, P28223, P11712, P23975, P31513, P08913, P18089, P08588]	DRUG_AND_METABOLITE	8.41518E-05
N02CC04	rizatriptan	C0004093	asthenia	1	[P28223]	DRUG_AND_METABOLITE	0.027162705
M04AA01	allopurinol	C0020517	hypersensitivity	1	[P00533]	METABOLITE	0.222747961
A07EC01	sulfasalazine	C0030305	pancreatitis	5	[Q99895, P05181, P00918, P09211, P35354]	DRUG_AND_METABOLITE	0.000164354
N04BC05	pramipexole	C0034212	pyoderma	1	[P07550]	DRUG	0.48095289
C07AB03	atenolol	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.003425546
D05BB02	acitretin	C0030193	pain	1	[P11511]	METABOLITE	0.03201379
M01AH03	valdecoxib	C0004093	asthenia	3	[P31645, P28223, P35354]	DRUG_AND_METABOLITE	0.000366068
A08AA10	sibutramine	C0027651	tumor	4	[P08684, Q01959, P23975, P35348]	METABOLITE	0.493022258
N02CC01	sumatriptan	C0026650	movement disorders	1	[P14416]	DRUG	0.107484566
C08CA05	nifedipine	C0041912	upper respiratory tract infection	1	[Q13936]	DRUG	0.49135126
L01XE03	erlotinib	C0023895	liver disease	2	[Q13177, P08684]	DRUG_AND_METABOLITE	0.440704116
A02BC01	omeprazole	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.086631975
N06AB08	fluvoxamine	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.072104339
N06AA04	clomipramine	C0018681	headache	1	[P29475]	METABOLITE	0.12745769
M01AG01	mefenamic acid	C0019080	hemorrhage	1	[P11712]	DRUG	0.042475697
N04AC01	benztropine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
J05AE03	ritonavir	C0019158	hepatitis	1	[P05181]	DRUG	0.093864358
N06AA06	trimipramine	C0033975	psychosis	8	[P35462, P28223, P21917, Q13639, P21397, P28222, P31645, P08908]	DRUG_AND_METABOLITE	4.55542E-05
A02BA02	ranitidine	C0011991	diarrhea	1	[P46098]	DRUG	0.039009407
G03CA03	estradiol	C0007820	cerebrovascular disorder	1	[P12104]	DRUG	0.422857188
N04BC04	ropinirole	C0023798	lipoma	1	[P05177]	DRUG	0.4999421
D07AC08	fluocinonide	C0021311	infection	1	[P04150]	DRUG	0.127583335
C09AA06	quinapril	C0004604	back pain	1	[P12821]	DRUG_AND_METABOLITE	0.001849681
C09CA02	eprosartan	C0022116	ischemia	1	[P50052]	DRUG	0.047068793
N05BC01	meprobamate	C0012833	dizziness	1	[P29274]	METABOLITE	0.056501401
N04BC04	ropinirole	C0043144	wheezing	1	[P07550]	DRUG	0.326920196
S01AA14	penicillin G	C0020538	hypertension	1	[P18054]	METABOLITE	0.433894116
J01MA01	ofloxacin	C0006266	bronchospasm	1	[P33527]	DRUG	0.257146572
N07BB04	naltrexone	C0027051	myocardial infarction	1	[P31645]	DRUG	0.222747961
N01AH01	fentanyl	C1527304	allergic reaction	1	[P41595]	DRUG	0.060203322
A02BC03	lansoprazole	C0036572	seizures	1	[P50993]	DRUG_AND_METABOLITE	0.060772541
M01AH03	valdecoxib	C1458155	breast neoplasm	9	[P08684, P35354, P33527, Q16790, P49137, Q99720, P08842, Q01959, O43570]	DRUG_AND_METABOLITE	0.488328094
C09AA03	lisinopril	C0016199	flank pain	1	[P12821]	DRUG	0.002297402
M01AH01	celecoxib	C0020456	hyperglycemia	1	[P35354]	DRUG_AND_METABOLITE	0.177107476
S01AA14	penicillin G	C0020517	hypersensitivity	1	[Q01959]	DRUG	0.158026147
M04AA01	allopurinol	C0011603	dermatitis	2	[P08107, Q07343]	METABOLITE	0.353629051
L04AX02	thalidomide	C0040046	thrombophlebitis	1	[P00488]	METABOLITE	0.277397428
J05AE01	saquinavir	C0008031	chest pain	1	[P02768]	DRUG	0.017292056
G03BA03	testosterone	C0006145	breast disorders	1	[P03372]	METABOLITE	0.089763822
M01AC01	piroxicam	C0021311	infection	3	[P35354, P23219, P09917]	DRUG	0.023624254
J01MA01	ofloxacin	C0018790	cardiac arrest	1	[Q12809]	DRUG_AND_METABOLITE	0.050141944
J01MA01	ofloxacin	C0018799	heart disease	3	[Q12809, Q92887, P33527]	DRUG	0.021169216
N01AH01	fentanyl	C0003123	anorexia	5	[P28223, P28335, P21397, P41143, P14416]	DRUG	4.03358E-07
N05BE01	buspirone	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.010316539
M01AE09	flurbiprofen	C0003864	arthritis	3	[P25025, P25024, P07858]	DRUG	0.008812138
C02AC01	clonidine	C0018524	hallucinations	1	[P08183]	DRUG	0.115394253
C01BC03	propafenone	C0018944	hematoma	1	[P11712]	DRUG	0.048951084
J01AA08	minocycline	C0231528	myalgia	1	[P01584]	DRUG	0.102405075
M01AG01	mefenamic acid	C0019158	hepatitis	2	[P23219, P35354]	DRUG	0.006002348
N02AX02	tramadol	C0022104	irritable bowel syndrome	1	[P31645]	DRUG_AND_METABOLITE	0.042804682
G03CA03	estradiol	C0037763	spasm	3	[P18507, P14867, P28472]	DRUG_AND_METABOLITE	0.001248928
B05BC01	mannitol	C0040046	thrombophlebitis	2	[P01008, P29460]	METABOLITE	0.100174684
N06AA01	desipramine	C0006266	bronchospasm	5	[P07550, P05362, P23219, P11229, P20309]	DRUG	0.08498899
M01AB02	sulindac	C0017152	gastritis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.010207101
N06AB05	paroxetine	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG	1.38448E-06
N06AB08	fluvoxamine	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG_AND_METABOLITE	3.39333E-07
N01BB09	ropivacaine	C0019080	hemorrhage	1	[P11712]	METABOLITE	0.086839232
C08CA04	nicardipine	C0027051	myocardial infarction	3	[P11712, P33261, P18089]	DRUG	0.111998404
J01MA02	ciprofloxacin	C0149931	migraine	1	[P08684]	DRUG	0.060203322
P01BC02	mefloquine	C0086769	panic attacks	1	[P29274]	DRUG	0.037092814
N02AE01	buprenorphine	C0009806	constipation	1	[P31645]	DRUG	0.03222962
C01DA02	nitroglycerin	C0016382	flushing	1	[P05091]	DRUG	0.0074084
V03AH01	diazoxide	C0015230	rash	1	[P07550]	DRUG	0.127783868
N06AA04	clomipramine	C0018524	hallucinations	6	[P08183, P36544, P35498, Q99250, P04156, Q9NY46]	DRUG_AND_METABOLITE	0.00086326
L02BA01	tamoxifen	C0029456	osteoporosis	6	[P03372, P11511, P08684, P04798, P10275, Q92731]	DRUG_AND_METABOLITE	3.77933E-05
N06AA04	clomipramine	C0020453	hyperesthesia	1	[Q8NER1]	METABOLITE	0.086098006
M01AB05	diclofenac	C0023890	cirrhosis	5	[P34972, P08684, P05181, P21554, O15439]	DRUG	0.007405387
J05AE01	saquinavir	C0008350	cholelithiasis	1	[P21439]	DRUG	0.051348531
N01BB01	bupivacaine	C0023895	liver disease	1	[P08684]	DRUG_AND_METABOLITE	0.203140248
G04BE03	sildenafil	C0151744	myocardial ischemia	1	[Q12809]	DRUG	0.112841395
J05AF03	zalcitabine	C0018524	hallucinations	1	[P33527]	DRUG	0.120607843
L04AA13	leflunomide	C0553662	juvenile rheumatoid arthritis	4	[Q9UM07, P03956, P05177, Q02127]	DRUG_AND_METABOLITE	0.00773235
G03DA04	progesterone	C0008925	cleft palate	1	[P28472]	METABOLITE	0.222757824
G03DA04	progesterone	C0008924	cleft lip	1	[P28472]	METABOLITE	0.222757824
L01AA01	cyclophosphamide	C0027947	neutropenia	1	[P08183]	DRUG	0.042804682
C07AB02	metoprolol	C0042514	ventricular tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.022511552
J01DB01	cephalexin	C0022658	nephropathy	1	[P02768]	DRUG	0.073573636
N06AA04	clomipramine	C0151827	eye pain	1	[Q8NER1]	METABOLITE	0.120607843
N05BB01	hydroxyzine	C1527304	allergic reaction	2	[P35367, Q9H3N8]	DRUG	0.005103777
J01MA01	ofloxacin	C0018801	heart failure	1	[Q12809]	DRUG_AND_METABOLITE	0.094186093
N06AX16	venlafaxine	C0013146	abuse	1	[P41595]	DRUG	0.047698503
M01AB05	diclofenac	C0011603	dermatitis	2	[P28223, P08908]	DRUG	0.257836071
L01BA01	methotrexate	C0020517	hypersensitivity	1	[P42898]	DRUG	0.114204701
L04AX04	lenalidomide	C0019080	hemorrhage	1	[P11712]	DRUG	0.06495498
J01MA02	ciprofloxacin	C0009319	colitis	1	[P08183]	DRUG	0.147069696
N02AE01	buprenorphine	C0011991	diarrhea	1	[O60656]	DRUG	0.045203907
J05AE07	fosamprenavir	C0019080	hemorrhage	1	[P11712]	METABOLITE	0.047592614
C09CA07	telmisartan	C0010709	cyst	7	[P08183, Q07869, Q92887, P10826, Q9UNQ0, P37231, Q03181]	DRUG	0.004808724
N06AA21	maprotiline	C0033975	psychosis	3	[P35462, P28223, P31645]	DRUG_AND_METABOLITE	0.001615827
N02AD01	pentazocine	C0009806	constipation	1	[P46098]	DRUG	0.028561234
L01BB02	mercaptopurine	C0021390	inflammatory bowel disease	1	[P51580]	DRUG	0.112841395
A10BB09	gliclazide	C0042029	urinary tract infection	1	[P15692]	DRUG	0.015294093
N06AA09	amitriptyline	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.001215327
N05AB04	prochlorperazine	C0242422	Parkinson	7	[P21917, Q01959, P50406, P08908, P31645, P14416, P35462]	DRUG_AND_METABOLITE	1.40434E-05
C10AA05	atorvastatin	C0020565	breast enlargement	1	[P27487]	DRUG_AND_METABOLITE	0.080482871
G03AC06	medroxyprogesterone	C0006266	bronchospasm	1	[P04150]	DRUG_AND_METABOLITE	0.168492591
C08DB01	diltiazem	C0242184	hypoxia	1	[Q12809]	DRUG	0.339889802
C02AC01	clonidine	C0018802	congestive heart failure	1	[Q9Y2I1]	DRUG	0.123348216
S01AA14	penicillin G	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.017771337
H05BX01	cinacalcet	C0020598	hypocalcemia	1	[P41180]	DRUG	0.009521978
C01BB02	mexiletine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.010316539
N06BA04	methylphenidate	C1527304	allergic reaction	2	[P41595, Q01959]	DRUG_AND_METABOLITE	0.019575297
C02CA04	doxazosin	C0011603	dermatitis	2	[P28223, P08908]	METABOLITE	0.077843187
C07AG02	carvedilol	C0024115	lung disorder	8	[P08183, P07550, P47989, P15692, P05181, P04798, P31645, P05177]	DRUG	3.22952E-06
N06AX21	duloxetine	C0575081	abnormal gait	2	[P35498, Q12791]	DRUG	0.017783546
L04AX01	azathioprine	C0231218	malaise	1	[Q08499]	METABOLITE	0.034569231
N06AF03	phenelzine	C0033975	psychosis	2	[P21397, P31645]	DRUG	0.016701405
N05AX12	aripiprazole	C0004134	ataxia	1	[P05129]	DRUG_AND_METABOLITE	0.159051487
C09CA07	telmisartan	C0041912	upper respiratory tract infection	3	[Q96RI1, P37231, Q07869]	DRUG	0.048334546
N06AB06	sertraline	C0020542	pulmonary hypertension	1	[P31645]	DRUG_AND_METABOLITE	0.112841395
N07XX02	riluzole	C0033860	psoriasis	1	[P04798]	DRUG	0.134972174
N03AB02	phenytoin	C0009806	constipation	1	[Q14524]	DRUG	0.049333365
N06AB06	sertraline	C0020538	hypertension	11	[P19099, P35348, P21728, P31645, P28223, P11511, P11712, P23975, P08913, P18089, P08588]	DRUG	5.50721E-07
N06AB06	sertraline	C0020565	breast enlargement	2	[P11511, P19099]	METABOLITE	0.027175081
N03AX11	topiramate	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.265101728
N04BC05	pramipexole	C0011603	dermatitis	4	[P07550, P28223, P08908, P31645]	DRUG	0.03159839
H05BX01	cinacalcet	C0020538	hypertension	1	[P31645]	DRUG	0.158026147
M01AG01	mefenamic acid	C0027051	myocardial infarction	4	[P35354, P10275, P11712, P23219]	DRUG	0.00171444
N04BC02	pergolide	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.034424934
R06AA04	clemastine	C0009951	convulsions	1	[P31645]	DRUG	0.115394253
C10AB04	gemfibrozil	C0011603	dermatitis	2	[P37231, Q07869]	DRUG	0.032472209
R03AC02	salbutamol	C0043144	wheezing	1	[P07550]	DRUG	0.092356341
L01XX05	hydroxyurea	C0030305	pancreatitis	1	[P00918]	METABOLITE	0.063596471
N06AB06	sertraline	C0020517	hypersensitivity	2	[Q01959, P35367]	DRUG_AND_METABOLITE	0.02486339
A03BA01	atropine	C0015230	rash	3	[P47712, P28223, P08908]	DRUG	0.021040008
N06AA04	clomipramine	C0020550	hyperthyroidism	2	[P07550, P08183]	DRUG_AND_METABOLITE	0.093529817
N05BE01	buspirone	C0085762	alcohol abuse	9	[P28223, P31645, P21728, P08908, P35462, P14416, P08172, P35372, P25103]	METABOLITE	0
N02CC04	rizatriptan	C0038454	cerebrovascular accident	1	[P28223]	DRUG_AND_METABOLITE	0.126632267
G04BD07	tolterodine	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.031415297
J01MA02	ciprofloxacin	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.108434198
N07BC02	methadone	C0039231	tachycardia	2	[P07550, P08588]	METABOLITE	0.005170758
N06AA04	clomipramine	C0020569	salivary gland enlargement	2	[Q14643, P20309]	METABOLITE	0.124490194
N02AA01	morphine	C1510472	drug dependence	1	[P21964]	DRUG_AND_METABOLITE	0.028123725
C08CA05	nifedipine	C0006266	bronchospasm	1	[P29274]	DRUG	0.426935507
L02BB03	bicalutamide	C0027051	myocardial infarction	3	[P03372, P10275, P04150]	DRUG	0.00225078
R06AA04	clemastine	C0009806	constipation	1	[P31645]	DRUG	0.021299045
C01BA03	disopyramide	C0428977	bradycardia	1	[Q14524]	DRUG	0.012309865
G03BA03	testosterone	C0022658	nephropathy	2	[P02768, P00918]	METABOLITE	0.134436346
A08AA10	sibutramine	C1527304	allergic reaction	2	[P41595, Q01959]	DRUG_AND_METABOLITE	0.008554931
N03AB02	phenytoin	C0011991	diarrhea	1	[Q92887]	DRUG	0.070199651
C10AA02	lovastatin	C0030305	pancreatitis	5	[P05362, P05181, P07858, P00325, P05091]	METABOLITE	0.090174716
G04BE03	sildenafil	C0151825	bone pain	1	[Q08499]	DRUG	0.022963468
G04BE03	sildenafil	C0151827	eye pain	1	[Q08499]	DRUG	0.054232974
M01AH01	celecoxib	C0027121	myositis	3	[P23219, P35354, P09917]	DRUG	0.010538298
P02CA01	mebendazole	C0027947	neutropenia	1	[P08183]	DRUG	0.032885129
C09AA04	perindopril	C0023530	leukopenia	1	[P08183]	DRUG	0.023338897
N07BA01	nicotine	C0009806	constipation	2	[A5X5Y0, P46098]	DRUG	0.004003741
A03FA03	domperidone	C0009806	constipation	2	[P46098, P41595]	DRUG	0.001282425
A03FA02	cisapride	C0004096	asthma	1	[P07550]	DRUG	0.378573515
J05AE04	nelfinavir	C0022346	jaundice	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.019839873
N06AA04	clomipramine	C0014175	endometriosis	1	[P09211]	DRUG	0.479371404
C01BB02	mexiletine	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.306764942
N02CC04	rizatriptan	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.001442409
N03AG01	valproic acid	C0019080	hemorrhage	1	[P11712]	DRUG	0.11409462
N05AA01	chlorpromazine	C0020615	hypoglycemia	2	[P07550, P30874]	DRUG	0.085527439
C09AA02	enalapril	C0042109	urticaria	1	[P12821]	DRUG_AND_METABOLITE	0.033976159
N06AA04	clomipramine	C0020517	hypersensitivity	7	[P41595, Q8NER1, Q01959, P29475, P35367, P25021, Q9H3N8]	METABOLITE	6.31065E-05
L01BA01	methotrexate	C0020433	bilirubinemia	3	[Q92887, Q9Y6L6, Q9NPD5]	DRUG	0.000301591
N06AA12	doxepin	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.094288684
G02CB01	bromocriptine	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.000810085
N03AX09	lamotrigine	C0019080	hemorrhage	1	[P11712]	DRUG	0.054359067
G03AC06	medroxyprogesterone	C0006145	breast disorders	1	[P03372]	DRUG_AND_METABOLITE	0.021841092
C01CA24	epinephrine	C0020538	hypertension	12	[P35348, P13945, P07550, P21728, O15244, P28223, P11712, P23975, P08913, P18089, P08588, P18054]	METABOLITE	0
C09AA07	benazepril	C0038454	cerebrovascular accident	2	[P42898, P12821]	DRUG_AND_METABOLITE	0.004655935
A02BC01	omeprazole	C0023222	leg pain	1	[Q8NER1]	DRUG	0.021299045
L01XE01	imatinib	C0008031	chest pain	1	[P02768]	DRUG	0.092781485
N02AA01	morphine	C0033975	psychosis	4	[P21964, P35462, P21917, P31645]	METABOLITE	0.000627876
N06AA04	clomipramine	C0151744	myocardial ischemia	3	[P07550, P08588, Q12809]	METABOLITE	0.033141645
A16AA04	cysteamine	C0152459	striae	1	[P09211]	DRUG	0.238279559
C01CA24	epinephrine	C0020550	hyperthyroidism	1	[P07550]	DRUG_AND_METABOLITE	0.102909805
N05AX12	aripiprazole	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.008738741
N05AX12	aripiprazole	C0004096	asthma	4	[P07550, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.109049755
M01AE03	ketoprofen	C0011991	diarrhea	1	[P10145]	DRUG	0.039009407
M01AB05	diclofenac	C1527304	allergic reaction	3	[P41595, P35367, P25021]	DRUG	0.005953569
M01AH02	rofecoxib	C0042029	urinary tract infection	1	[P03973]	DRUG	0.065209929
N05AX08	risperidone	C0041912	upper respiratory tract infection	1	[P07550]	DRUG_AND_METABOLITE	0.499236835
A02BA02	ranitidine	C0023895	liver disease	2	[P21439, P08684]	DRUG	0.026322863
N02CC03	zolmitriptan	C0015230	rash	1	[P08908]	DRUG	0.121293293
C03DA01	spironolactone	C0001824	agranulocytosis	2	[Q92887, P08183]	DRUG	0.003912895
L02AB01	megestrol	C0040046	thrombophlebitis	1	[P03372]	DRUG	0.047831182
J05AE01	saquinavir	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.040204533
C10AA03	pravastatin	C0024141	lupus	1	[Q92887]	DRUG_AND_METABOLITE	0.233518101
N07BB04	naltrexone	C0009806	constipation	1	[P31645]	DRUG	0.022436068
N02CC03	zolmitriptan	C0009951	convulsions	1	[P08908]	DRUG	0.115394253
M01AB15	ketorolac	C0027051	myocardial infarction	5	[P35354, P10145, P02768, P11712, P23219]	DRUG	0.001986914
M01AE03	ketoprofen	C0036690	Septicemia	1	[P10145]	DRUG	0.106657016
M03BB03	chlorzoxazone	C0002792	anaphylaxis	1	[P35228]	DRUG	0.059919612
C07AB03	atenolol	C0003123	anorexia	2	[P28223, P28335]	DRUG	0.004163713
J01MA02	ciprofloxacin	C0009951	convulsions	1	[P08183]	DRUG	0.133868815
N03AX16	pregabalin	C0004998	skin benign neoplasm	1	[Q01650]	DRUG	0.404857952
M03BX08	cyclobenzaprine	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.105539171
N04BD01	selegiline	C0020538	hypertension	10	[P35348, P21728, P31645, P28223, P11712, P23975, P08913, P18089, P08588, P11086]	METABOLITE	2.24958E-05
M01AX01	nabumetone	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.014088111
J01AA08	minocycline	C0014868	esophagitis	1	[P01584]	DRUG	0.035667691
N01AH01	fentanyl	C0035078	renal failure	1	[P08183]	DRUG	0.080911313
M01AH02	rofecoxib	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.00017745
J05AE01	saquinavir	C0024115	lung disorder	1	[P08183]	DRUG	0.244277487
N05BE01	buspirone	C0033975	psychosis	7	[P35462, P28223, P21917, Q13639, P28222, P31645, P08908]	DRUG_AND_METABOLITE	1.17834E-05
L02BG03	anastrozole	C0476089	endometrial cancer	2	[P11511, P08684]	DRUG_AND_METABOLITE	0.030227902
N05AX12	aripiprazole	C0041912	upper respiratory tract infection	2	[P07550, P17252]	DRUG_AND_METABOLITE	0.472671612
R03BA08	ciclesonide	C0021311	infection	1	[P04150]	DRUG	0.180184941
N06BA09	atomoxetine	C0040822	tremor	1	[Q14643]	DRUG	0.043962389
C07AA03	pindolol	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.002100895
N05AH03	olanzapine	C0036337	schizoaffective disorder	20	[P35462, P28223, P36544, P11229, P08912, P21917, P14416, P28472, P47870, P28335, P21728, P08908, P31645, Q01959, P25103, P50406, P35367, P17787, P08173, O95264]	DRUG	0
A05AA02	ursodeoxycholic acid	C0002871	anemia	1	[P11473]	METABOLITE	0.071241753
C01BA01	quinidine	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.016169699
N04BC05	pramipexole	C0011849	diabetes mellitus	3	[O15245, P18089, P07550]	DRUG	0.114580337
L01XE01	imatinib	C0035078	renal failure	1	[P08183]	DRUG	0.449505259
N04BB01	amantadine	C1527304	allergic reaction	2	[P35367, Q9H3N8]	METABOLITE	0.019059388
L02BA01	tamoxifen	C0149871	deep vein thrombosis	2	[P03372, Q92731]	DRUG_AND_METABOLITE	0.031878908
S01ED02	betaxolol	C0007820	cerebrovascular disorder	1	[P07550]	DRUG_AND_METABOLITE	0.16773657
N07BC02	methadone	C0018524	hallucinations	1	[P08183]	DRUG	0.203641648
M01AG01	mefenamic acid	C0030920	peptic ulcer	2	[P35354, P23219]	DRUG	0.003004332
N05CA01	pentobarbital	C0018524	hallucinations	6	[P08183, P36544, P35498, Q99250, P33527, Q9NY46]	DRUG	9.71969E-06
G03DA04	progesterone	C0022346	jaundice	2	[Q9Y6L6, P11413]	METABOLITE	0.00560082
N05AX08	risperidone	C0012813	diverticulitis	1	[P31645]	DRUG_AND_METABOLITE	0.097563145
N04BC04	ropinirole	C0009319	colitis	2	[P46098, P41595]	DRUG	0.077274451
L02BA01	tamoxifen	C0010709	cyst	15	[P05177, P11509, P08183, P05771, P03372, P35354, Q92731, Q9UNQ0, P11511, P20815, P05181, Q16678, P04798, P10275, P17252]	METABOLITE	0.002791594
N06DA03	rivastigmine	C0003123	anorexia	2	[P21397, P31645]	DRUG	0.001810163
L01XE03	erlotinib	C0006826	cancer	92	[P04626, P42336, P08183, P29317, P00533, Q9UIK4, P31749, Q9UK32, Q15375, Q02763, P37173, P36897, P10721, P53350, P51955, P45983, Q16539, P21802, P22607, P45985, Q9P289, P07333, P09619, P16234, Q08345, P43405, O75582, Q13153, P08581, P15056, Q92918, Q15831, P07949, O14965, P43403, P12931, P53355, Q9UNQ0, P50613, P08069, Q96GD4, Q13873, Q05397, O43293, Q13882, P08684, Q16832, P04629, P35916, P17948, O14757, P45984, P35968, P54762, P54760, P49841, O60674, P07332, P28482, P11362, Q9UM73, P52333, Q02156, Q05655, P27361, P06213, P24941, P00519, P29597, P29323, P19525, P22455, P06239, P68400, P53667, Q13164, P24723, P36894, P07948, Q00526, P06241, O95835, P21709, Q02750, P31751, P36507, Q15303, Q14289, Q9Y243, P49840, Q9NRM7, P23458]	DRUG_AND_METABOLITE	0.000360584
N02CC01	sumatriptan	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.01008194
A05AA02	ursodeoxycholic acid	C0041912	upper respiratory tract infection	2	[P11473, Q96RI1]	DRUG_AND_METABOLITE	0.153324068
N04BC05	pramipexole	C0027651	tumor	7	[Q99720, Q01959, Q9H3N8, Q9Y5N1, P23975, P35348, P07550]	DRUG	0.499995859
G04CA02	tamsulosin	C0024115	lung disorder	1	[P35354]	METABOLITE	0.264874933
N02CC04	rizatriptan	C0015672	fatigue	1	[P28223]	DRUG_AND_METABOLITE	0.027162705
C09CA07	telmisartan	C0027051	myocardial infarction	4	[P37231, P30556, Q07869, P33261]	DRUG	0.003958486
N05AX08	risperidone	C0242422	Parkinson	10	[P21917, Q01959, P32238, P08183, P21554, P50406, P08908, P31645, P14416, P35462]	DRUG_AND_METABOLITE	1.45615E-05
L01XX11	estramustine	C0040046	thrombophlebitis	2	[P03372, Q92731]	DRUG_AND_METABOLITE	0.034678316
C09AA04	perindopril	C0035078	renal failure	2	[P12821, P08183]	DRUG	0.001208821
G03AC06	medroxyprogesterone	C0018799	heart disease	3	[P03372, P11712, P04150]	DRUG_AND_METABOLITE	0.005766453
G03CA03	estradiol	C0021311	infection	1	[P03372]	DRUG_AND_METABOLITE	0.499995859
M03BX08	cyclobenzaprine	C0008031	chest pain	1	[P02768]	DRUG_AND_METABOLITE	0.044322867
C07AG02	carvedilol	C0041912	upper respiratory tract infection	5	[P07550, P15692, P19320, P47989, P23219]	DRUG	0.025073757
N06AX11	mirtazapine	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG	0.003144473
G03BA03	testosterone	C0010709	cyst	17	[P05177, P08183, P06401, P03372, Q92731, P08842, Q9UNQ0, P31213, P11511, P20815, Q16678, P50225, P22309, P18405, P04798, P10275, P11474]	METABOLITE	0.161207473
M01AB08	etodolac	C0009319	colitis	1	[P35354]	DRUG_AND_METABOLITE	0.133313088
C01BC04	flecainide	C0022116	ischemia	1	[Q14524]	DRUG	0.06437545
N07BB04	naltrexone	C0015230	rash	1	[P31645]	DRUG	0.127783868
M01AE12	oxaprozin	C0019158	hepatitis	2	[P23219, P35354]	DRUG	0.00271628
N02CC01	sumatriptan	C0039483	temporal arteritis	1	[Q92731]	METABOLITE	0.088180739
L04AX02	thalidomide	C0009319	colitis	3	[P01375, P19838, P35354]	DRUG_AND_METABOLITE	0.209546795
G03CA03	estradiol	C0007286	carpal tunnel syndrome	1	[P03372]	DRUG_AND_METABOLITE	0.054931462
M01AE01	ibuprofen	C0035078	renal failure	2	[P08183, P41222]	DRUG	0.080458605
N05AD01	haloperidol	C0023530	leukopenia	2	[O60656, P08183]	DRUG	0.044555324
L04AX02	thalidomide	C0040460	Toothache	1	[Q08499]	DRUG	0.04898487
L01XE01	imatinib	C0011603	dermatitis	2	[P04629, Q9UKE5]	DRUG	0.499995859
N06AA02	imipramine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.022328811
H02AB06	prednisolone	C0027813	neuritis	1	[P08183]	DRUG_AND_METABOLITE	0.074342707
N05BE01	buspirone	C0015230	rash	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	METABOLITE	0.004898515
G02CB03	cabergoline	C0004093	asthenia	1	[P28223]	DRUG	0.037086334
C03BA04	chlorthalidone	C0030305	pancreatitis	2	[Q99895, P00918]	DRUG	0.016280057
M01AH02	rofecoxib	C0042109	urticaria	1	[P09917]	DRUG_AND_METABOLITE	0.090245404
N04BC04	ropinirole	C0011991	diarrhea	1	[P46098]	DRUG	0.052118018
N06AB04	citalopram	C0151744	myocardial ischemia	2	[P08588, Q12809]	DRUG	0.017115097
G04CB02	dutasteride	C0027651	tumor	6	[P08684, P14060, P20815, P18405, P31213, P26439]	DRUG_AND_METABOLITE	0.019389846
N05AX12	aripiprazole	C0086769	panic attacks	5	[P08908, P28223, P46098, P31645, P23975]	DRUG_AND_METABOLITE	1.64738E-05
C01BA01	quinidine	C0018790	cardiac arrest	3	[Q14524, Q12809, Q13936]	DRUG	0.001506986
N06AX16	venlafaxine	C0013604	edema	1	[P08588]	DRUG	0.074076931
N02CC06	eletriptan	C0442874	neuropathy	1	[P08183]	DRUG	0.074254786
A07EC01	sulfasalazine	C0023530	leukopenia	1	[Q92887]	DRUG	0.085235597
N03AB02	phenytoin	C0042510	ventricular fibrillation	1	[Q14524]	DRUG	0.020824645
P01AX06	atovaquone	C0006266	bronchospasm	11	[P07550, P50135, P09211, P48506, P29508, P01024, P42898, P11229, P29274, P20309, P12931]	METABOLITE	0.014913288
N05AD01	haloperidol	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.00054791
C09AA04	perindopril	C0018801	heart failure	1	[P12821]	DRUG_AND_METABOLITE	0.035667691
J01AA08	minocycline	C0024141	lupus	5	[P14780, P42574, P01584, P15692, Q9H244]	DRUG	0.001450138
A02BC01	omeprazole	C0023895	liver disease	1	[P08684]	DRUG_AND_METABOLITE	0.180499559
J05AG03	efavirenz	C0006826	cancer	2	[P08684, P05177]	DRUG	0.349805559
N05AH04	quetiapine	C0011206	delirium	2	[P32238, P21554]	DRUG	0.009279632
L04AX01	azathioprine	C0231528	myalgia	2	[P17252, Q08499]	METABOLITE	0.063596471
R06AD02	promethazine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.09230254
C09AA03	lisinopril	C0041948	uremia	1	[P12821]	DRUG	0.050504261
N06DA03	rivastigmine	C0010054	coronary artery disease	2	[P08684, P06276]	DRUG	0.019575297
L02BA01	tamoxifen	C0019158	hepatitis	4	[P05181, P23219, P35354, P11509]	DRUG	0.000895018
N05AC02	thioridazine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	6.78667E-07
C07AA05	propranolol	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	9.13424E-05
C10AA03	pravastatin	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.09523719
C09AA01	captopril	C0019158	hepatitis	1	[P02768]	DRUG	0.096593322
N06AA04	clomipramine	C0006325	bruxism	1	[P31645]	DRUG_AND_METABOLITE	0.039106452
M01AE12	oxaprozin	C0019080	hemorrhage	1	[P11712]	DRUG	0.031230552
C09AA04	perindopril	C0018799	heart disease	1	[P12821]	DRUG_AND_METABOLITE	0.080618312
M01AE01	ibuprofen	C0027051	myocardial infarction	11	[P35354, P10145, P02768, P21554, P11712, P33261, P31645, P07451, P23219, P18089, P27695]	METABOLITE	0.001796868
C07AB02	metoprolol	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.040601904
P01AB01	metronidazole	C0027651	tumor	2	[P08684, P10632]	DRUG	0.252614158
L01XE01	imatinib	C0221247	avascular necrosis	1	[P08183]	DRUG	0.295862803
C09AA03	lisinopril	C0041912	upper respiratory tract infection	1	[Q9BYF1]	DRUG	0.14501301
G03BA03	testosterone	C0022346	jaundice	3	[Q9Y6L6, P22309, P11413]	DRUG_AND_METABOLITE	0.000178986
N03AB02	phenytoin	C0039231	tachycardia	1	[Q14524]	DRUG	0.045203907
C02KX01	bosentan	C0018801	heart failure	2	[P24530, P25101]	DRUG_AND_METABOLITE	0.002194013
M01AE09	flurbiprofen	C0038454	cerebrovascular accident	2	[P05067, P35354]	DRUG_AND_METABOLITE	0.064088815
N06AA04	clomipramine	C0018801	heart failure	4	[Q9Y2I1, Q12809, P07550, O43306]	METABOLITE	0.02099712
N05AH03	olanzapine	C0011849	diabetes mellitus	4	[P02768, P18089, P13945, P07550]	DRUG_AND_METABOLITE	0.112404615
A10BX03	nateglinide	C0041912	upper respiratory tract infection	2	[P23219, P37231]	DRUG_AND_METABOLITE	0.141091994
N02AE01	buprenorphine	C0009951	convulsions	2	[P08183, P31645]	DRUG	0.050351847
M01AH03	valdecoxib	C0010054	coronary artery disease	3	[P08684, P35354, P21554]	DRUG_AND_METABOLITE	0.105649776
J01AA08	minocycline	C0019158	hepatitis	2	[P01584, P02768]	DRUG	0.019854912
N04BC04	ropinirole	C0011849	diabetes mellitus	3	[P08684, P18089, P07550]	DRUG	0.060597648
G02CB01	bromocriptine	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.054018686
R06AX02	cyproheptadine	C0043144	wheezing	5	[P07550, Q9Y271, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.066092419
M04AA01	allopurinol	C0027813	neuritis	1	[P60891]	METABOLITE	0.168748805
L04AX04	lenalidomide	C0023467	AML	4	[P05177, P04798, P19838, P01375]	DRUG	0.00772744
M01AC06	meloxicam	C0009951	convulsions	1	[P35354]	DRUG_AND_METABOLITE	0.096195732
N07BC02	methadone	C0018790	cardiac arrest	3	[Q12809, P18089, P07550]	METABOLITE	0.002795416
L02BA01	tamoxifen	C0021311	infection	4	[P03372, P35354, P23219, P17252]	METABOLITE	0.190378398
J05AG03	efavirenz	C0149931	migraine	1	[P08684]	DRUG	0.046871884
A07EC01	sulfasalazine	C0023890	cirrhosis	5	[P19971, P08684, P05181, P37231, P09211]	DRUG	0.000593081
N06AA12	doxepin	C0013395	Dyspepsia	1	[P23219]	METABOLITE	0.086888609
L01XB01	procarbazine	C0021311	infection	1	[P47989]	DRUG	0.098169818
G04BE03	sildenafil	C0030193	pain	1	[Q08499]	DRUG	0.039009407
G04BE03	sildenafil	C0030196	Pain in limb	1	[Q08499]	DRUG	0.022963468
M04AB01	probenecid	C0151798	hepatic necrosis	2	[Q92887, P08684]	DRUG	0.045785731
C02KX01	bosentan	C0018799	heart disease	1	[P11712]	DRUG_AND_METABOLITE	0.092452629
N06AB03	fluoxetine	C0030193	pain	1	[Q08499]	METABOLITE	0.05003687
C08CA06	nimodipine	C0012833	dizziness	1	[P29274]	DRUG	0.013961737
N05CF03	zaleplon	C0011168	dysphagia	1	[P03956]	METABOLITE	0.024401265
G04BE03	sildenafil	C0699893	skin carcinoma	2	[P05181, P04798]	DRUG	0.395205672
N04BC04	ropinirole	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.001465281
C09AA06	quinapril	C0004096	asthma	1	[P12821]	DRUG_AND_METABOLITE	0.077274451
C09AA06	quinapril	C0004093	asthenia	1	[P12821]	DRUG_AND_METABOLITE	0.010207101
N06AA06	trimipramine	C0004134	ataxia	2	[P35498, Q14643]	METABOLITE	0.096910793
N06AB05	paroxetine	C0027813	neuritis	1	[P08183]	DRUG	0.092781485
J05AF03	zalcitabine	C0022408	arthrosis	1	[P61073]	DRUG	0.168674498
L04AX02	thalidomide	C0314719	dry eyes	1	[P22735]	METABOLITE	0.058400414
N05CD08	midazolam	C0018524	hallucinations	1	[P08183]	DRUG	0.112949868
C02AC01	clonidine	C0085610	sinus bradycardia	1	[Q9Y3Q4]	DRUG	0.020153847
N06AA04	clomipramine	C0010200	cough	1	[Q8NER1]	METABOLITE	0.050141944
C09CA07	telmisartan	C0015230	rash	2	[P37231, Q07869]	DRUG	0.028123725
A02BB01	misoprostol	C0020538	hypertension	1	[Q07869]	METABOLITE	0.191738887
N07BB04	naltrexone	C0009951	convulsions	3	[P08183, P36544, P31645]	DRUG	0.003514802
N04BC02	pergolide	C0009319	colitis	1	[P41595]	DRUG_AND_METABOLITE	0.228549248
L04AA06	mycophenolic acid	C0009319	colitis	1	[P37231]	DRUG_AND_METABOLITE	0.072686205
N02AA01	morphine	C0003123	anorexia	6	[P21964, P21917, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	4.90821E-07
M01AB05	diclofenac	C0011991	diarrhea	4	[P10145, P46098, O60656, P16662]	DRUG	6.22083E-05
N01BA02	procaine	C0039231	tachycardia	1	[Q14524]	DRUG	0.050504261
R03AC02	salbutamol	C0020538	hypertension	3	[P13945, P07550, P08588]	DRUG	0.000812846
N06AX16	venlafaxine	C0013595	eczema	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.048676004
A07EA06	budesonide	C0002792	anaphylaxis	1	[P35228]	METABOLITE	0.085527439
N02AX02	tramadol	C0006266	bronchospasm	1	[P20309]	DRUG	0.210510758
N06AB05	paroxetine	C0027651	tumor	7	[P08183, P20813, Q01959, P10632, Q9UBN4, P23975, P35348]	DRUG	0.499995859
J01DD04	ceftriaxone	C0022658	nephropathy	1	[P02768]	DRUG	0.052883334
N02CC01	sumatriptan	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.003434146
A10BB09	gliclazide	C0009319	colitis	1	[P15692]	DRUG	0.072686205
C01BD01	amiodarone	C0039231	tachycardia	2	[Q14524, P08588]	DRUG	0.001248928
L02BA01	tamoxifen	C0029927	ovarian cyst	1	[P35354]	DRUG	0.089763822
N07BC02	methadone	C0018801	heart failure	3	[Q9Y2I1, Q12809, P07550]	METABOLITE	0.020619485
C09AA09	fosinopril	C0038454	cerebrovascular accident	1	[P12821]	DRUG	0.047753035
N06AX06	nefazodone	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.226285484
C02CA04	doxazosin	C0020517	hypersensitivity	1	[Q9H3N8]	METABOLITE	0.084863615
C02AC01	clonidine	C0011570	mental depression	5	[P28223, P21397, P28222, P23975, P18825]	DRUG	6.16908E-06
M01AB05	diclofenac	C0023530	leukopenia	4	[P16662, O60656, P22309, P08183]	DRUG	0.000540063
N06AA01	desipramine	C0018802	congestive heart failure	2	[Q12809, P07550]	DRUG	0.084103037
N05AH03	olanzapine	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.014022221
G04CA03	terazosin	C0003123	anorexia	5	[P28223, P21917, P28335, P28221, P14416]	DRUG_AND_METABOLITE	2.63993E-05
M01AB15	ketorolac	C0032285	pneumonia	2	[P10145, P35354]	DRUG	0.015087595
B01AC07	dipyridamole	C0020538	hypertension	1	[Q08499]	DRUG	0.266990805
M01AB05	diclofenac	C0035078	renal failure	1	[P08183]	DRUG	0.190068597
P02CA03	albendazole	C0001824	agranulocytosis	1	[P08183]	DRUG	0.037092814
G03AC06	medroxyprogesterone	C0013080	Trisomy 21	2	[P08183, P03372]	DRUG_AND_METABOLITE	0.032920219
N03AF02	oxcarbazepine	C0030319	panic disorder	2	[P33261, P08684]	DRUG	0.001767684
N06AX06	nefazodone	C0021311	infection	1	[P07550]	METABOLITE	0.488170395
M01AX01	nabumetone	C0013295	duodenal ulcer	1	[P35354]	DRUG_AND_METABOLITE	0.026393713
N06AA04	clomipramine	C0018790	cardiac arrest	4	[Q12809, Q13936, P18089, P07550]	DRUG_AND_METABOLITE	0.00145582
J05AE03	ritonavir	C0019080	hemorrhage	1	[P11712]	DRUG	0.06495498
N04BC05	pramipexole	C0011991	diarrhea	1	[P46098]	DRUG	0.067909151
L02BA02	toremifene	C0011603	dermatitis	3	[P09488, P09211, P30711]	METABOLITE	0.190378398
N04BC02	pergolide	C0149931	migraine	4	[P28223, P21917, P08684, P28335]	DRUG_AND_METABOLITE	9.13424E-05
R01AC03	azelastine	C1527304	allergic reaction	1	[P35367]	DRUG	0.050945221
C01BB02	mexiletine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.094719012
A07EA06	budesonide	C0002871	anemia	2	[P07148, P35228]	METABOLITE	0.028957228
N05AB06	trifluoperazine	C0013384	dyskinesia	6	[Q14643, P35498, Q12791, P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.000772249
J01AA02	doxycycline	C0002871	anemia	2	[P02768, O14746]	DRUG	0.01337726
C01BC03	propafenone	C0006384	bundle branch block	1	[Q14524]	DRUG	0.005809415
N02CC03	zolmitriptan	C0027651	tumor	1	[P05177]	DRUG	0.499995859
C10AX09	ezetimibe	C0041912	upper respiratory tract infection	1	[P15144]	DRUG	0.210928081
N05CF01	zopiclone	C0038358	gastric ulcer	1	[P23219]	DRUG	0.053108318
N02AA03	hydromorphone	C0019080	hemorrhage	1	[P11712]	DRUG	0.096593322
C08CA02	felodipine	C0021311	infection	4	[P03372, Q13936, Q16548, P04150]	DRUG	0.152175558
N02AX02	tramadol	C0005586	bipolar disorder	2	[P31645, P23975]	DRUG_AND_METABOLITE	0.017738848
G03BA03	testosterone	C0030193	pain	1	[P11511]	DRUG_AND_METABOLITE	0.071241753
C09CA04	irbesartan	C0035078	renal failure	1	[P30556]	DRUG_AND_METABOLITE	0.063874646
A07EA06	budesonide	C0149931	migraine	2	[P35228, P08684]	DRUG_AND_METABOLITE	0.021223297
N04BC02	pergolide	C0018802	congestive heart failure	1	[P07550]	DRUG	0.123348216
M01AE01	ibuprofen	C0027947	neutropenia	4	[P16662, O60656, P22309, P08183]	DRUG	0.000555149
C10AB05	fenofibrate	C0008325	cholecystitis	1	[P37231]	DRUG_AND_METABOLITE	0.033221489
N06AX06	nefazodone	C0013595	eczema	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.012309865
D05BB02	acitretin	C0015230	rash	2	[P21731, Q13258]	METABOLITE	0.062782178
C09AA09	fosinopril	C0021311	infection	1	[P12821]	DRUG	0.127583335
N04BC04	ropinirole	C0023055	laryngeal neoplasia	1	[P05177]	DRUG	0.4999421
N05AA01	chlorpromazine	C0021311	infection	11	[P05107, P07550, P04156, Q13936, P05362, P47989, P35354, P23219, P04629, P17252, P09917]	DRUG	0.306667139
R03BA08	ciclesonide	C0020538	hypertension	1	[P04150]	DRUG	0.106277208
A10BB09	gliclazide	C0041912	upper respiratory tract infection	1	[P15692]	DRUG	0.168674498
R06AX02	cyproheptadine	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG	1.17834E-05
M01AB02	sulindac	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.100095257
C08CA01	amlodipine	C0149931	migraine	1	[P08684]	DRUG	0.082078386
C10AA07	rosuvastatin	C0003864	arthritis	1	[P27487]	DRUG	0.074423797
N06AB06	sertraline	C0009806	constipation	1	[P31645]	DRUG_AND_METABOLITE	0.042436544
M01AE09	flurbiprofen	C0020456	hyperglycemia	3	[P35354, P10145, P07148]	DRUG	0.002413065
C02AC01	clonidine	C0015672	fatigue	1	[P28223]	DRUG	0.042475697
C07AG02	carvedilol	C0042029	urinary tract infection	1	[P15692]	DRUG	0.040204533
J01MA06	norfloxacin	C0013390	dysmenorrhea	1	[P04798]	DRUG	0.013399503
A07EA06	budesonide	C0011991	diarrhea	1	[Q92887]	METABOLITE	0.061653521
J05AB04	ribavirin	C0011849	diabetes mellitus	2	[P22413, Q99808]	DRUG	0.038869302
J01AA08	minocycline	C0014518	toxic epidermal necrolysis	2	[P14780, P08253]	DRUG_AND_METABOLITE	0.000256201
N05CD02	nitrazepam	C0011991	diarrhea	1	[P46098]	DRUG	0.091830722
N06AA11	protriptyline	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000374019
A10BX02	repaglinide	C0018802	congestive heart failure	1	[P37231]	DRUG	0.05003687
J01MA07	lomefloxacin	C0023530	leukopenia	1	[Q92887]	DRUG	0.044087091
C01BD01	amiodarone	C0006826	cancer	8	[P08183, P20815, P10632, P04798, P08684, P05177, P10828, Q12809]	DRUG	0.116501515
A02BC04	rabeprazole	C0034065	pulmonary embolism	1	[P02768]	DRUG_AND_METABOLITE	0.059505271
A02BC01	omeprazole	C0149931	migraine	2	[P50993, P08684]	DRUG_AND_METABOLITE	0.017596968
A02BC03	lansoprazole	C0232726	tenesmus	1	[Q9Y6L6]	METABOLITE	0.105895855
N06AX11	mirtazapine	C0497327	dementia	2	[P08908, P31645]	DRUG	0.112133252
L01XE01	imatinib	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.230774572
M01AC01	piroxicam	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.015405718
N04BC02	pergolide	C0678222	breast cancer	2	[P08684, Q99720]	DRUG	0.499995859
C10AB05	fenofibrate	C0004096	asthma	4	[Q13258, P08246, Q9Y5Y4, P37231]	DRUG_AND_METABOLITE	0.001986914
S01JA01	fluorescein	C0006266	bronchospasm	1	[P33527]	DRUG	0.179324562
C09AA01	captopril	C0032285	pneumonia	1	[P14780]	DRUG	0.100095257
S01ED02	betaxolol	C0020615	hypoglycemia	1	[P07550]	DRUG_AND_METABOLITE	0.056501401
C09CA04	irbesartan	C0039231	tachycardia	1	[P30556]	DRUG_AND_METABOLITE	0.019687894
N06AB08	fluvoxamine	C0027051	myocardial infarction	6	[P04798, P11712, P33261, P31645, P05177, P08588]	DRUG_AND_METABOLITE	0.00116466
M01AB05	diclofenac	C0027651	tumor	21	[P04798, P08684, P10145, P35354, P08183, P42330, P33527, Q16790, P22309, Q99720, P05181, P05177, P20813, P10632, Q9Y5N1, P23219, O15439, P33261, P34972, P21554, P35348]	DRUG	0.376904013
S01ED02	betaxolol	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.026766868
M01AB05	diclofenac	C0001824	agranulocytosis	4	[P16662, O60656, P22309, P08183]	DRUG	0.000220233
C07AA05	propranolol	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.000751627
N06DA02	donepezil	C0011603	dermatitis	1	[P28223]	DRUG	0.158889462
C09AA05	ramipril	C0020615	hypoglycemia	1	[P12821]	DRUG	0.019381901
J01FA01	erythromycin	C0009951	convulsions	2	[P08183, P33527]	DRUG	0.035667691
N06DA02	donepezil	C0004093	asthenia	1	[P28223]	DRUG	0.024401265
N06DA02	donepezil	C0004096	asthma	2	[P49682, P23219]	DRUG	0.054232974
N05CF01	zopiclone	C0021311	infection	1	[P23219]	DRUG	0.414892114
C08CA01	amlodipine	C0019158	hepatitis	1	[P11509]	DRUG	0.105026994
N07BB04	naltrexone	C0015672	fatigue	1	[P31645]	DRUG	0.025953097
H02AB02	dexamethasone	C0030920	peptic ulcer	4	[P35228, P35354, P33261, P23219]	DRUG_AND_METABOLITE	0.000205438
A02BA02	ranitidine	C0023530	leukopenia	1	[P08183]	DRUG	0.059748572
L01AA01	cyclophosphamide	C0035078	renal failure	1	[P08183]	DRUG	0.07118586
B01AC05	ticlopidine	C0035078	renal failure	1	[P05164]	DRUG_AND_METABOLITE	0.107239949
N01BB01	bupivacaine	C0039231	tachycardia	1	[Q14524]	METABOLITE	0.040283843
N05AB04	prochlorperazine	C0021311	infection	1	[Q07820]	DRUG	0.443039998
N01BB09	ropivacaine	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	METABOLITE	0.000343989
N03AB02	phenytoin	C0428977	bradycardia	1	[Q14524]	DRUG	0.027044096
C08DA01	verapamil	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.184639656
N05AX08	risperidone	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.040753047
N03AB02	phenytoin	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.021138685
N06AB03	fluoxetine	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG	0.007247507
N05BA02	chlordiazepoxide	C0004134	ataxia	1	[P35498]	DRUG	0.194973853
C07AG02	carvedilol	C0206061	interstitial pneumonitis	1	[P15692]	DRUG	0.090670352
R06AX02	cyproheptadine	C0009951	convulsions	7	[P35498, Q9UBS5, P36544, Q99250, Q9NY46, P08908, P31645]	DRUG	0.000651955
L01BA01	methotrexate	C0085584	encephalopathy	1	[P08183]	DRUG	0.117450419
C10AB05	fenofibrate	C0042373	Vascular Disorders	1	[P37231]	DRUG_AND_METABOLITE	0.07797371
A10BX03	nateglinide	C0019158	hepatitis	1	[P23219]	DRUG_AND_METABOLITE	0.075243023
N04BB01	amantadine	C0020538	hypertension	6	[P35348, O15244, Q9Y2I1, P11712, P08913, P18089]	DRUG	0.00510073
G03XC01	raloxifene	C0006826	cancer	6	[P03372, Q92731, Q13393, P10632, P08684, P11511]	DRUG	0.098169818
S01ED02	betaxolol	C0020473	hyperlipidemia	1	[P07550]	DRUG_AND_METABOLITE	0.090174716
N05AX08	risperidone	C0023530	leukopenia	1	[P08183]	DRUG	0.14059695
M01AB05	diclofenac	C0027726	nephrotic syndrome	4	[P07148, P35354, P02768, P10145]	DRUG_AND_METABOLITE	0.039806384
M01AE09	flurbiprofen	C0020538	hypertension	1	[P11712]	DRUG	0.32893333
C07AG02	carvedilol	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.054232974
S01ED02	betaxolol	C0013595	eczema	2	[P07550, P08908]	METABOLITE	0.035667691
J01AA08	minocycline	C0036974	shock	2	[P01584, P08253]	DRUG_AND_METABOLITE	0.005625009
N02CC03	zolmitriptan	C0023903	Hepatic neoplasms	1	[P05177]	DRUG	0.314346526
C09AA09	fosinopril	C0006266	bronchospasm	1	[P12821]	DRUG	0.077274451
C09AA08	cilazapril	C0149931	migraine	1	[P12821]	DRUG	0.026766868
A02BA02	ranitidine	C0027947	neutropenia	1	[P08183]	DRUG	0.05003687
N05BA01	diazepam	C0002871	anemia	2	[P02768, P07148]	DRUG	0.039903358
N02AA01	morphine	C0015230	rash	1	[P31645]	METABOLITE	0.25753957
N06AB05	paroxetine	C0010709	cyst	2	[P08183, P23975]	DRUG_AND_METABOLITE	0.497068996
N04BB01	amantadine	C0003123	anorexia	1	[P14416]	DRUG	0.108059528
N05AX08	risperidone	C0149931	migraine	5	[P28223, P21917, P31645, P08684, P28335]	DRUG_AND_METABOLITE	0.000125975
N04BC04	ropinirole	C0011615	atopic dermatitis	3	[P07550, P28223, P08908]	DRUG	0.021040008
N06AB06	sertraline	C0009951	convulsions	3	[P08183, P08908, P31645]	DRUG_AND_METABOLITE	0.027144316
N05AX08	risperidone	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.090174716
N06AX06	nefazodone	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.048595777
C09AA08	cilazapril	C0042373	Vascular Disorders	1	[P12821]	DRUG	0.039025321
M01AE01	ibuprofen	C0023530	leukopenia	4	[P16662, O60656, P22309, P08183]	DRUG	0.001338912
N04BC04	ropinirole	C0011603	dermatitis	3	[P07550, P28223, P08908]	DRUG	0.040204533
G03XA01	danazol	C0001430	adenomas	3	[P03372, P06401, P05093]	METABOLITE	0.028123725
C10AA02	lovastatin	C0023890	cirrhosis	5	[P08684, P05181, P20701, P05362, P10515]	METABOLITE	0.183906186
N05AB06	trifluoperazine	C0020615	hypoglycemia	2	[P07550, P30874]	DRUG	0.085527439
A02BC03	lansoprazole	C0023055	laryngeal neoplasia	5	[P05177, P08183, Q9UNQ0, Q16678, P04798]	DRUG	0.207603065
N02CC06	eletriptan	C0013595	eczema	1	[P08908]	DRUG	0.127783868
C07AA06	timolol	C0085649	peripheral edema	1	[P08588]	DRUG	0.021299045
N04BX01	tolcapone	C0600139	prostate cancer	3	[P21964, P06493, P27487]	METABOLITE	0.284881531
N05AG02	pimozide	C0001824	agranulocytosis	2	[O60656, P08183]	DRUG	0.032040111
N03AG06	tiagabine	C0004096	asthma	2	[P11229, P20309]	DRUG	0.16144089
N06DA02	donepezil	C0020538	hypertension	2	[P28223, P11712]	DRUG	0.054970991
B01AC05	ticlopidine	C0023418	leukemia	3	[P05164, P04798, P35354]	DRUG_AND_METABOLITE	0.157350877
R01AC03	azelastine	C0002103	allergic rhinitis	1	[P11712]	DRUG	0.082956716
C09AA10	trandolapril	C0149931	migraine	1	[P12821]	DRUG_AND_METABOLITE	0.026766868
L04AX04	lenalidomide	C0002962	angina pectoris	1	[P01375]	DRUG	0.060772541
L01AA01	cyclophosphamide	C0027051	myocardial infarction	3	[P11712, P33261, P23219]	DRUG	0.023218364
N03AG01	valproic acid	C0021311	infection	4	[Q9UBN7, P13726, P23219, O15379]	DRUG	0.245556276
A02BC02	pantoprazole	C0020538	hypertension	4	[P05026, P05023, Q02928, P11712]	DRUG_AND_METABOLITE	0.019687894
N01BA02	procaine	C0162297	respiratory arrest	1	[Q9UQD0]	DRUG	0.089405514
C02CA01	prazosin	C0015672	fatigue	1	[P28223]	DRUG_AND_METABOLITE	0.056501401
C09AA04	perindopril	C0003811	arrhythmia	1	[P12821]	DRUG_AND_METABOLITE	0.013961737
N06BA07	modafinil	C0003123	anorexia	2	[P21964, P23975]	DRUG	0.004163713
A07EA06	budesonide	C0149725	lower respiratory infection	1	[P05113]	DRUG	0.061653521
L04AX04	lenalidomide	C0002940	aneurysm	1	[P01375]	DRUG	0.060772541
C03CA01	furosemide	C0012833	dizziness	1	[P29274]	DRUG	0.019687894
J05AE03	ritonavir	C0022346	jaundice	1	[Q9Y6L6]	DRUG	0.021841092
G04BE09	vardenafil	C0010054	coronary artery disease	2	[P08684, Q08499]	DRUG	0.093159412
L04AX04	lenalidomide	C0442874	neuropathy	1	[P19838]	DRUG	0.092835044
N05CF03	zaleplon	C0039070	syncope	1	[P29274]	DRUG	0.019239124
L02BB03	bicalutamide	C0015672	fatigue	1	[P04150]	DRUG	0.014253709
A02BC02	pantoprazole	C0020517	hypersensitivity	1	[P25021]	METABOLITE	0.098579167
N06AB03	fluoxetine	C0013604	edema	1	[P08588]	DRUG	0.054232974
A02BB01	misoprostol	C0021311	infection	1	[Q07869]	METABOLITE	0.311927901
N06AB04	citalopram	C0013295	duodenal ulcer	1	[P33261]	DRUG	0.061653521
C01BC03	propafenone	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.030408848
A10BX02	repaglinide	C0020538	hypertension	2	[P37231, P21728]	METABOLITE	0.028748417
C07AA06	timolol	C0010054	coronary artery disease	1	[P13945]	DRUG	0.153656891
N03AG06	tiagabine	C0004134	ataxia	2	[P80404, Q99259]	DRUG	0.017560596
N06AA11	protriptyline	C0033975	psychosis	6	[P35462, P28223, Q13639, P28222, P31645, P08908]	DRUG	9.70269E-05
A10BB02	chlorpropamide	C0001824	agranulocytosis	1	[P08183]	DRUG	0.076642524
B01AC05	ticlopidine	C0027726	nephrotic syndrome	2	[P05164, P35354]	DRUG_AND_METABOLITE	0.07824382
N04BC02	pergolide	C0004096	asthma	1	[P07550]	DRUG	0.326920196
N04BC02	pergolide	C0004093	asthenia	1	[P28223]	DRUG_AND_METABOLITE	0.042475697
N06AX16	venlafaxine	C0024115	lung disorder	6	[P08183, P07550, P29274, P21452, P31645, P29475]	DRUG	0.033221489
L04AX04	lenalidomide	C0024299	lymphoma	2	[P19838, P35354]	DRUG	0.091184812
N01BB01	bupivacaine	C0042514	ventricular tachycardia	1	[Q14524]	METABOLITE	0.040283843
L01XE03	erlotinib	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.444496803
N01BB01	bupivacaine	C0042510	ventricular fibrillation	1	[Q14524]	METABOLITE	0.01884128
N02AA05	oxycodone	C0149931	migraine	2	[P31645, P08684]	DRUG_AND_METABOLITE	0.003300583
L01XX35	anagrelide	C0149931	migraine	2	[P28223, P28335]	METABOLITE	0.004954116
C07AA07	sotalol	C0018801	heart failure	2	[Q12809, P07550]	DRUG	0.007694241
C07AA05	propranolol	C0009319	colitis	4	[P08183, P31645, P46098, P41595]	DRUG	0.012664293
N05AA01	chlorpromazine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.107647419
D08AC02	chlorhexidine	C0019080	hemorrhage	2	[P14780, P08253]	DRUG	0.001465281
A10BA02	metformin	C0020538	hypertension	2	[P27487, O15244]	DRUG	0.018841569
C09AA10	trandolapril	C0021311	infection	2	[Q9BYF1, P12821]	DRUG_AND_METABOLITE	0.034852775
J01EC02	sulfadiazine	C0019158	hepatitis	2	[P05181, P02768]	METABOLITE	0.007046132
N04BD01	selegiline	C0033975	psychosis	6	[P35462, P28223, P21397, P28222, P31645, P08908]	DRUG_AND_METABOLITE	9.71969E-06
N06AA04	clomipramine	C0033860	psoriasis	1	[Q05586]	DRUG_AND_METABOLITE	0.437918936
D05BB02	acitretin	C0027813	neuritis	3	[P10276, P10826, P19793]	DRUG_AND_METABOLITE	0.000648878
N06AA12	doxepin	C0018681	headache	1	[P05362]	METABOLITE	0.128383818
C10AB02	bezafibrate	C0015230	rash	2	[P37231, Q07869]	DRUG	0.036120827
M03BX08	cyclobenzaprine	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.036939077
N02AA01	morphine	C0021311	infection	2	[P23219, P01189]	METABOLITE	0.388888656
N04BC05	pramipexole	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.000384154
N06DA02	donepezil	C0011849	diabetes mellitus	3	[P06276, P11712, P08684]	DRUG	0.013399503
C10AA02	lovastatin	C0023530	leukopenia	1	[P08183]	DRUG	0.321772517
C09AA01	captopril	C0015230	rash	3	[P14780, P08253, P09211]	METABOLITE	0.011918531
N06BA01	amphetamine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.117381457
N06AA12	doxepin	C0004134	ataxia	2	[Q09470, P35498]	DRUG_AND_METABOLITE	0.089912296
A10BX02	repaglinide	C0020615	hypoglycemia	1	[Q09428]	DRUG	0.032885129
N05AX08	risperidone	C0009319	colitis	4	[P08183, P31645, P46098, P41595]	DRUG_AND_METABOLITE	0.039053536
N06AB03	fluoxetine	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.051696381
C01BC04	flecainide	C0178428	sinus arrest	1	[Q14524]	DRUG	0.017783546
A07EA06	budesonide	C0011603	dermatitis	1	[P05113]	DRUG	0.327236684
N05CD02	nitrazepam	C0023530	leukopenia	1	[P08183]	DRUG	0.143731103
N05AD01	haloperidol	C0686347	tardive dyskinesia	1	[P35498]	DRUG	0.085428589
G03DA04	progesterone	C0008031	chest pain	1	[P02768]	METABOLITE	0.044087091
N05AX12	aripiprazole	C0149931	migraine	5	[P28223, P21917, P31645, P08684, P28335]	DRUG_AND_METABOLITE	0.000107249
N06AA17	amoxapine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.00637323
C09AA07	benazepril	C0027051	myocardial infarction	2	[P12821, P42898]	DRUG	0.016596235
C09AA07	benazepril	C0033687	proteinuria	1	[P12821]	DRUG_AND_METABOLITE	0.019687894
J01FA10	azithromycin	C0020538	hypertension	1	[P20815]	DRUG_AND_METABOLITE	0.258878236
A01AC01	triamcinolone	C0017601	glaucoma	1	[P04150]	DRUG	0.020153847
G03XA01	danazol	C0009951	convulsions	2	[P13500, P08908]	METABOLITE	0.050351847
C09AA02	enalapril	C0031117	peripheral neuropathy	2	[P12821, P08183]	DRUG	0.000774385
D10AX03	azelaic acid	C0042900	vitiligo	1	[P14679]	DRUG	0.021299045
L01XE01	imatinib	C0031256	petechiae	1	[P08581]	DRUG	0.276586801
A07EA06	budesonide	C0043144	wheezing	6	[P09917, P05113, P04150, P35354, P23219, P35228]	METABOLITE	0.004358747
C09AA08	cilazapril	C0042109	urticaria	1	[P12821]	DRUG	0.018096702
N03AG01	valproic acid	C0085584	encephalopathy	3	[P14867, P18505, P18507]	DRUG	0.007353659
M01AC06	meloxicam	C0020538	hypertension	1	[P11712]	DRUG	0.158026147
C02CA04	doxazosin	C0085584	encephalopathy	1	[P08183]	DRUG	0.087048961
L01DB06	idarubicin	C0019080	hemorrhage	1	[P11712]	DRUG	0.02394431
N02CC06	eletriptan	C0013395	Dyspepsia	1	[P23219]	DRUG	0.021600815
N03AX11	topiramate	C0030305	pancreatitis	1	[P00918]	DRUG	0.12507432
M01AB08	etodolac	C0030305	pancreatitis	2	[Q99895, P35354]	DRUG_AND_METABOLITE	0.016280057
C01EB03	indomethacin	C0018802	congestive heart failure	2	[P25101, P37231]	DRUG	0.056140305
S01ED02	betaxolol	C0004134	ataxia	1	[P35498]	METABOLITE	0.065976505
N06BA04	methylphenidate	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG_AND_METABOLITE	1.77828E-06
N06AA12	doxepin	C0018524	hallucinations	7	[P08183, P36544, O43526, P35498, Q99250, P04156, Q9NY46]	DRUG_AND_METABOLITE	0.000164814
C02CA04	doxazosin	C0007097	carcinoma	4	[P08183, P04818, Q9H3N8, Q12809]	DRUG	0.41387924
L01XE03	erlotinib	C0040034	thrombocytopenia	1	[O60674]	DRUG_AND_METABOLITE	0.327279171
N04BC05	pramipexole	C0042109	urticaria	1	[P07550]	DRUG	0.080482871
C01EB03	indomethacin	C0018834	heartburn	1	[P23219]	DRUG_AND_METABOLITE	0.050504261
M01AE01	ibuprofen	C0243026	sepsis	1	[P10145]	DRUG	0.328440501
R06AX17	ketotifen	C0020538	hypertension	5	[Q08499, P35348, P21728, P28223, P08913]	METABOLITE	0.008645525
N06BA04	methylphenidate	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.063596471
J02AC03	voriconazole	C0030305	pancreatitis	1	[P00918]	METABOLITE	0.085892844
N06AA06	trimipramine	C0040822	tremor	1	[Q14643]	METABOLITE	0.073814713
M03CA01	dantrolene	C0011570	mental depression	1	[P08684]	DRUG	0.031878908
N02AA03	hydromorphone	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.010538298
N03AG06	tiagabine	C0027651	tumor	3	[P08684, O00591, P35348]	DRUG	0.499995859
N06AX16	venlafaxine	C0009806	constipation	4	[Q14524, P46098, P41595, P31645]	DRUG_AND_METABOLITE	2.24499E-05
N07XX02	riluzole	C0040136	thyroid neoplasia	4	[P05177, O15554, Q9UNQ0, P04798]	DRUG	0.149189442
C02CA04	doxazosin	C0003864	arthritis	1	[Q9H3N8]	METABOLITE	0.127182501
N07AX01	pilocarpine	C0042024	urinary incontinence	1	[P08172]	DRUG	0.022436068
M01AB08	etodolac	C0021311	infection	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.14501301
L04AA06	mycophenolic acid	C0014130	Endocrine Disorders	1	[P37231]	DRUG_AND_METABOLITE	0.086440059
C07AG02	carvedilol	C0039231	tachycardia	3	[Q14524, P07550, P08588]	DRUG_AND_METABOLITE	2.08794E-05
J05AE07	fosamprenavir	C0019693	HIV infection	3	[P20815, P20813, P08684]	DRUG_AND_METABOLITE	0.002581488
N02AA03	hydromorphone	C0018802	congestive heart failure	1	[Q12809]	DRUG_AND_METABOLITE	0.145448571
N01AH01	fentanyl	C0027651	tumor	6	[P08684, P08183, Q99720, P20815, Q9UBN4, Q12809]	DRUG	0.327509865
J01DC04	cefaclor	C0024115	lung disorder	1	[Q16348]	DRUG	0.144529733
H02AA02	fludrocortisone	C0029456	osteoporosis	2	[P08684, P10275]	DRUG_AND_METABOLITE	0.013067174
N06BA04	methylphenidate	C0011849	diabetes mellitus	1	[P18089]	DRUG_AND_METABOLITE	0.382742428
N05BE01	buspirone	C0022104	irritable bowel syndrome	3	[P46098, P41595, P31645]	METABOLITE	0.003814028
M01AH03	valdecoxib	C0010709	cyst	5	[O43570, P35354, P33527, Q16790, P08842]	DRUG_AND_METABOLITE	0.482721351
N07BC02	methadone	C0013604	edema	1	[P08588]	METABOLITE	0.062137552
N06AB03	fluoxetine	C0085649	peripheral edema	1	[P08588]	DRUG	0.054232974
J01AA08	minocycline	C0020538	hypertension	5	[P01584, P14780, P08254, P08253, P15692]	DRUG	0.003480725
M01AE03	ketoprofen	C0027726	nephrotic syndrome	5	[P15121, P07148, P35354, P02768, P10145]	DRUG	0.000178986
C07AB04	acebutolol	C0043144	wheezing	1	[P07550]	DRUG	0.144785429
L04AX02	thalidomide	C0023222	leg pain	1	[Q08499]	DRUG	0.04898487
B01AC05	ticlopidine	C0027121	myositis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.017418215
N06BA09	atomoxetine	C0021311	infection	2	[P07550, P17252]	DRUG	0.476685306
N05AE04	ziprasidone	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG	8.41518E-05
G04BE03	sildenafil	C0019080	hemorrhage	1	[P11712]	DRUG	0.09498999
A02BC01	omeprazole	C0016059	fibrosis	1	[P04798]	DRUG_AND_METABOLITE	0.23796335
C09AA09	fosinopril	C0015672	fatigue	1	[P12821]	DRUG	0.010207101
N05AG02	pimozide	C0018799	heart disease	8	[Q12809, P31645, P08588, P51681, P11712, P07550, O95259, P41595]	DRUG	0.005814835
J05AF06	abacavir	C0027947	neutropenia	1	[P22309]	DRUG	0.022511552
M01AH01	celecoxib	C0011849	diabetes mellitus	6	[P11712, O15245, P08684, P35354, P18089, P10632]	DRUG	0.02336218
N06AA09	amitriptyline	C0024141	lupus	1	[P05362]	METABOLITE	0.486867751
N06AA17	amoxapine	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.020490582
A08AB01	orlistat	C0004096	asthma	1	[Q13093]	DRUG	0.190102925
N04BC04	ropinirole	C0015672	fatigue	1	[P28223]	DRUG	0.042475697
L01CB01	etoposide	C0027051	myocardial infarction	2	[O95255, P05177]	DRUG_AND_METABOLITE	0.123597305
C08CA01	amlodipine	C0027051	myocardial infarction	3	[P04798, P11712, P05177]	DRUG	0.057568219
N05CF01	zopiclone	C0037763	spasm	3	[P18507, P14867, P28472]	DRUG	5.45046E-05
L02BG06	exemestane	C0032584	polyps	4	[Q12809, P11511, P18405, P10275]	METABOLITE	0.013789483
A08AA10	sibutramine	C0011991	diarrhea	1	[P46098]	DRUG	0.042804682
M01AH01	celecoxib	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.206183114
A02BC03	lansoprazole	C0018524	hallucinations	2	[P08183, P50993]	DRUG_AND_METABOLITE	0.020819013
N01AH01	fentanyl	C0004093	asthenia	1	[P28223]	DRUG	0.030655726
N06DX01	memantine	C0020538	hypertension	1	[O15244]	DRUG	0.258878236
C02AC01	clonidine	C0015230	rash	1	[P28223]	DRUG	0.219564294
N05BE01	buspirone	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.005979133
A03FA01	metoclopramide	C0020538	hypertension	7	[P19099, P35348, P21728, P28223, P08913, P18089, P08588]	DRUG	0.000323796
M01AE01	ibuprofen	C0027651	tumor	26	[P10145, P35354, P08183, P27695, P42330, P33527, Q16790, P22309, Q99720, P18031, P46721, P09917, Q01959, P10632, Q9Y5N1, P23219, P25025, O43570, P05187, P23975, P41222, O15439, P33261, P34972, P21554, P35348]	DRUG	0.459073606
C01DA08	isosorbide dinitrate	C0020538	hypertension	1	[P16066]	DRUG	0.092998912
M01AE09	flurbiprofen	C0018834	heartburn	1	[P23219]	DRUG_AND_METABOLITE	0.034424934
C09AA05	ramipril	C0013404	dyspnea	1	[P12821]	DRUG	0.014460868
A02BC03	lansoprazole	C0011849	diabetes mellitus	3	[P11712, P08684, P10632]	DRUG	0.051010353
A04AA02	granisetron	C0009806	constipation	3	[A5X5Y0, P46098, P41595]	DRUG	2.61117E-05
G04BE09	vardenafil	C0151827	eye pain	1	[Q08499]	DRUG	0.044396476
C03DB01	amiloride	C0037763	spasm	2	[P23415, P14867]	DRUG	0.006179944
C10AA01	simvastatin	C0231528	myalgia	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.073232497
L04AX04	lenalidomide	C0024117	COPD	7	[P01375, P35354, Q08499, P27815, P05181, P04798, P05177]	DRUG	1.8324E-06
M01AH03	valdecoxib	C0003123	anorexia	5	[P28223, P28335, P28221, P31645, P14416]	DRUG_AND_METABOLITE	6.22083E-05
C07AB03	atenolol	C0015672	fatigue	1	[P28223]	DRUG	0.024401265
H02AB07	prednisone	C0085660	Aseptic necrosis	1	[P08183]	DRUG_AND_METABOLITE	0.057088716
J01MA07	lomefloxacin	C0878544	cardiomyopathy	1	[O76082]	DRUG	0.078146652
J01MA02	ciprofloxacin	C0023530	leukopenia	1	[P08183]	DRUG	0.053194386
C08DA01	verapamil	C0009806	constipation	2	[Q14524, P31645]	DRUG	0.00515856
A10BG03	pioglitazone	C0022116	ischemia	1	[P37231]	DRUG_AND_METABOLITE	0.106277208
P01BC02	mefloquine	C0018524	hallucinations	1	[P08183]	DRUG	0.062319473
L01XX35	anagrelide	C0038454	cerebrovascular accident	1	[P28223]	METABOLITE	0.120356457
C07AA06	timolol	C0004093	asthenia	1	[P28223]	DRUG	0.024401265
N06AA21	maprotiline	C0038454	cerebrovascular accident	1	[P28223]	DRUG	0.166969633
N06AA01	desipramine	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.026665834
N01BA02	procaine	C0003811	arrhythmia	1	[Q14524]	DRUG	0.071241753
N04BC04	ropinirole	C0005747	blepharospasm	2	[P21918, P14416]	DRUG_AND_METABOLITE	0.009279632
D06BB10	imiquimod	C0024299	lymphoma	1	[Q9NYK1]	DRUG	0.088403141
N03AX14	levetiracetam	C0018524	hallucinations	1	[P08183]	DRUG	0.047149096
N06AX16	venlafaxine	C0009951	convulsions	7	[P35498, P08183, Q99250, Q9NY46, P08908, P31645, P29475]	DRUG	0.001847306
M01AH02	rofecoxib	C0006266	bronchospasm	6	[P09917, P35354, P23219, Q15722, P16050, P33527]	DRUG_AND_METABOLITE	0.014940513
L01XX05	hydroxyurea	C0011633	dermatomyositis	1	[P14780]	METABOLITE	0.033737522
N06BA01	amphetamine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.016169699
N06DA02	donepezil	C0015672	fatigue	1	[P28223]	DRUG	0.024401265
C09AA06	quinapril	C0003811	arrhythmia	1	[P12821]	DRUG_AND_METABOLITE	0.011557989
N03AG01	valproic acid	C0019158	hepatitis	2	[P23219, P11509]	DRUG	0.044972823
C10AA02	lovastatin	C0015230	rash	2	[P00352, P09601]	METABOLITE	0.470911096
C07AA06	timolol	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.295414647
L01XX05	hydroxyurea	C0011603	dermatitis	1	[P14780]	METABOLITE	0.110503219
M03BX08	cyclobenzaprine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	6.82659E-06
L01CB01	etoposide	C0085669	acute leukemia	8	[P11388, P08183, P42574, P20815, Q9UNQ0, O15438, P33527, P05177]	DRUG_AND_METABOLITE	0.000217973
N05AB02	fluphenazine	C0023530	leukopenia	1	[P08183]	DRUG	0.103918638
M01AH01	celecoxib	C0011991	diarrhea	1	[P46098]	DRUG	0.085261294
D10AA02	methylprednisolone	C0009951	convulsions	1	[P08183]	DRUG_AND_METABOLITE	0.082841128
C04AD03	pentoxifylline	C0002962	angina pectoris	1	[P01375]	DRUG_AND_METABOLITE	0.046668295
C01BD01	amiodarone	C0178428	sinus arrest	1	[Q14524]	DRUG	0.03201379
A02BC04	rabeprazole	C0004093	asthenia	1	[P35354]	DRUG	0.059505271
C07AG02	carvedilol	C0042514	ventricular tachycardia	2	[Q14524, P08588]	DRUG_AND_METABOLITE	0.001103492
M01AC01	piroxicam	C0020456	hyperglycemia	1	[P35354]	DRUG_AND_METABOLITE	0.047235322
A02BC04	rabeprazole	C0004096	asthma	2	[P35354, P23219]	DRUG	0.266295527
L02BB03	bicalutamide	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.105539171
C07AB03	atenolol	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.019687894
L02BA01	tamoxifen	C0014175	endometriosis	6	[P03372, Q92731, P56937, P11511, P35354, P04798]	DRUG_AND_METABOLITE	0.001308799
N06AB03	fluoxetine	C0018802	congestive heart failure	1	[Q12809]	DRUG	0.187936228
N06BA01	amphetamine	C0011206	delirium	1	[P21554]	METABOLITE	0.09498999
N02AA03	hydromorphone	C0018790	cardiac arrest	1	[Q12809]	DRUG_AND_METABOLITE	0.07705633
M01AC01	piroxicam	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.054232974
D11AX10	finasteride	C0027651	tumor	8	[P08684, P14060, P10275, P20815, P18405, P31213, P26439, P33261]	DRUG	0.037664292
N06AB03	fluoxetine	C0018790	cardiac arrest	2	[Q12809, P18089]	DRUG	0.017363576
N04BC04	ropinirole	C0009806	constipation	2	[P46098, P41595]	DRUG	0.00183769
C09AA08	cilazapril	C0013404	dyspnea	1	[P12821]	DRUG	0.017596968
N02AA01	morphine	C0015672	fatigue	1	[P31645]	METABOLITE	0.049355201
D05BB02	acitretin	C0039503	tendinitis	1	[P35408]	METABOLITE	0.009287022
A05AA02	ursodeoxycholic acid	C0018799	heart disease	3	[P11473, Q13133, Q92887]	DRUG_AND_METABOLITE	0.013961737
M01AE03	ketoprofen	C0020538	hypertension	1	[P11712]	DRUG	0.250256312
H02AA02	fludrocortisone	C0009951	convulsions	2	[P08183, P50993]	METABOLITE	0.023202726
N06AA01	desipramine	C0020565	breast enlargement	1	[P05362]	DRUG	0.209388562
N06BA04	methylphenidate	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.066476119
N06AA01	desipramine	C0020538	hypertension	13	[P20815, P35348, P13945, P07550, P21728, O15244, P31645, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG	0.000024432
G03CA03	estradiol	C0042133	uterine fibroids	6	[P03372, P21964, P04798, Q16678, P10275, Q92731]	DRUG_AND_METABOLITE	0.001906972
N06AX16	venlafaxine	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.114224804
M01AH02	rofecoxib	C0037763	spasm	2	[P14867, P21918]	DRUG_AND_METABOLITE	0.007486393
M01AC06	meloxicam	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.016701405
C02CA01	prazosin	C0015230	rash	2	[P28223, P08908]	DRUG_AND_METABOLITE	0.119473327
N05AH04	quetiapine	C0011991	diarrhea	1	[P46098]	DRUG	0.090174716
G03BA03	testosterone	C0015672	fatigue	1	[P08185]	METABOLITE	0.089763822
A07EC01	sulfasalazine	C0024141	lupus	1	[Q92887]	DRUG	0.296354734
M01AH03	valdecoxib	C0038358	gastric ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.017396684
J01MA01	ofloxacin	C0018524	hallucinations	2	[P08183, P33527]	DRUG	0.014253709
J05AE03	ritonavir	C0018524	hallucinations	2	[P08183, P33527]	DRUG	0.015294093
M01AH01	celecoxib	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG	0.128584946
J05AF03	zalcitabine	C0014549	grand mal	1	[P54098]	METABOLITE	0.072918638
L01XE02	gefitinib	C0151908	dry skin	1	[Q9UKE5]	DRUG_AND_METABOLITE	0.479535142
C09AA01	captopril	C0015672	fatigue	1	[P12821]	DRUG	0.035047926
N06DA02	donepezil	C0020473	hyperlipidemia	1	[P23219]	DRUG	0.072104339
M01AB08	etodolac	C0018834	heartburn	1	[P23219]	DRUG_AND_METABOLITE	0.020619485
N02CC01	sumatriptan	C0030319	panic disorder	6	[P08684, P05177, P08908, P28223, P21397, P46098]	DRUG	5.50721E-07
N06AB03	fluoxetine	C0013295	duodenal ulcer	1	[P33261]	DRUG	0.094186093
N06AA04	clomipramine	C0002736	als	3	[P09211, O60391, P29475]	METABOLITE	0.123945437
N02CC01	sumatriptan	C0030305	pancreatitis	2	[P05181, P04798]	METABOLITE	0.081233454
N05AB03	perphenazine	C0042024	urinary incontinence	2	[P28223, P21917]	DRUG	0.00560082
M01AB05	diclofenac	C0027051	myocardial infarction	10	[P35354, P10145, P02768, P21554, P04798, P11712, P33261, P23219, P05177, P18089]	DRUG	0.000723628
C10AA05	atorvastatin	C0004096	asthma	1	[P33527]	DRUG_AND_METABOLITE	0.24849921
N05BB01	hydroxyzine	C0015230	rash	1	[P28223]	DRUG	0.140985578
C09AA10	trandolapril	C0013404	dyspnea	1	[P12821]	DRUG_AND_METABOLITE	0.017596968
C07AB02	metoprolol	C0015230	rash	2	[P07550, P08908]	DRUG_AND_METABOLITE	0.033663054
L01XE02	gefitinib	C0151950	deep thrombophlebitis	2	[O60674, O14757]	DRUG_AND_METABOLITE	0.276348193
J01MA06	norfloxacin	C0019158	hepatitis	1	[P11509]	DRUG	0.078558694
R06AE07	cetirizine	C0022408	arthrosis	1	[Q9H3N8]	DRUG	0.045119841
M01AC01	piroxicam	C0020538	hypertension	1	[P11712]	DRUG	0.145881184
D06AA01	demeclocycline	C0014356	enterocolitis	1	[P08254]	DRUG	0.057987175
J01AA08	minocycline	C0014356	enterocolitis	2	[P15692, P08254]	DRUG_AND_METABOLITE	0.007501017
R01AA08	naphazoline	C0020538	hypertension	5	[P35348, P31645, Q9Y2I1, P08913, P18089]	DRUG	3.34351E-05
C04AD03	pentoxifylline	C0002874	aplastic anemia	1	[P01375]	DRUG_AND_METABOLITE	0.082956716
J01MA01	ofloxacin	C0027051	myocardial infarction	2	[P02768, P05177]	DRUG_AND_METABOLITE	0.11032208
C04AD03	pentoxifylline	C0002871	anemia	1	[P01375]	DRUG_AND_METABOLITE	0.064439777
G03AC06	medroxyprogesterone	C0029925	ovarian cancer	6	[P08183, P06401, P10275, P08684, P03372, P10632]	DRUG_AND_METABOLITE	7.26523E-05
L01XE03	erlotinib	C0006271	bronchiolitis	2	[P43405, P20783]	DRUG_AND_METABOLITE	0.308816105
C07AB03	atenolol	C0026266	mitral insufficiency	2	[P08588, P07550]	DRUG	0.029347211
N06AA10	nortriptyline	C0033975	psychosis	6	[P35462, P28223, Q13639, P28222, P31645, P08908]	DRUG	9.70269E-05
C08DB01	diltiazem	C0151744	myocardial ischemia	1	[Q12809]	DRUG	0.100424708
N02CC01	sumatriptan	C0026848	myopathy	2	[P10275, Q9Y6L6]	DRUG_AND_METABOLITE	0.07663301
N02CC01	sumatriptan	C0026846	muscle atrophy	2	[P10275, Q9Y6L6]	DRUG_AND_METABOLITE	0.048334546
N04BC04	ropinirole	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.021040008
G03HA01	cyproterone	C0029456	osteoporosis	3	[P11511, P08684, P10275]	DRUG	1.90271E-05
N06AB08	fluvoxamine	C0027651	tumor	11	[P04798, P08684, P08183, P05181, P05177, P20813, Q01959, P20815, P23975, P33261, P35348]	DRUG_AND_METABOLITE	0.136460144
L01XE03	erlotinib	C0024115	lung disorder	11	[P54646, Q02156, P08183, P41240, Q08345, P06239, Q05655, P35968, Q16539, P20783, P08631]	DRUG_AND_METABOLITE	0.103255892
N04BC04	ropinirole	C0009951	convulsions	1	[P08908]	DRUG	0.209262313
C08CA04	nicardipine	C0004153	atherosclerotic vascular disease	5	[P08684, Q13936, P54750, P11712, P33261]	DRUG	0.010731647
N01AH01	fentanyl	C0027947	neutropenia	1	[P08183]	DRUG	0.048334546
N06AB04	citalopram	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.055548179
A07EC04	balsalazide	C0023890	cirrhosis	1	[P37231]	DRUG_AND_METABOLITE	0.118928189
N06DA03	rivastigmine	C0007097	carcinoma	3	[P06276, P22303, P08684]	DRUG	0.146563091
N05CD01	flurazepam	C0001824	agranulocytosis	1	[P08183]	DRUG	0.056653613
N06AB03	fluoxetine	C0013146	abuse	1	[P41595]	DRUG_AND_METABOLITE	0.035667691
G03XC01	raloxifene	C0018799	heart disease	3	[P03372, Q92731, P20813]	DRUG	0.017749421
N05BC01	meprobamate	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.200446099
C07AG01	labetalol	C0013604	edema	1	[P08588]	DRUG	0.02023865
A02BC02	pantoprazole	C0016204	flatulence	1	[P08575]	METABOLITE	0.038275109
N06AB06	sertraline	C0009319	colitis	2	[P08183, P31645]	DRUG_AND_METABOLITE	0.097626877
N04BC04	ropinirole	C0151744	myocardial ischemia	2	[P07550, P08588]	DRUG	0.017783546
L04AX04	lenalidomide	C0600139	prostate cancer	12	[P35354, P19838, P01375, P21802, O14788, P20815, P05181, P04798, P23219, P05177, Q08499, P33261]	DRUG	0.000853923
N06AA04	clomipramine	C0002871	anemia	1	[P02768]	METABOLITE	0.283690142
G03BA03	testosterone	C0231528	myalgia	1	[Q9Y6L6]	METABOLITE	0.253963077
N04BC02	pergolide	C0018790	cardiac arrest	2	[P18089, P07550]	DRUG	0.007572786
G04CA03	terazosin	C0003864	arthritis	1	[Q9H3N8]	METABOLITE	0.215430517
N06AB05	paroxetine	C1527304	allergic reaction	3	[P41595, Q01959, P35367]	DRUG	0.001859038
N05AH04	quetiapine	C0011849	diabetes mellitus	3	[P08684, P18089, P07550]	DRUG	0.215112556
B05BC01	mannitol	C1527304	allergic reaction	3	[P29475, P10144, P35247]	METABOLITE	0.018613941
N02AA03	hydromorphone	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG_AND_METABOLITE	0.000590875
J05AE01	saquinavir	C0023895	liver disease	3	[P21439, Q92887, P08684]	DRUG	0.005849775
C07AG02	carvedilol	C0035078	renal failure	2	[P08183, P16860]	DRUG	0.018220595
N06AB08	fluvoxamine	C0004096	asthma	1	[P11229]	DRUG_AND_METABOLITE	0.294971197
M01AE12	oxaprozin	C0027051	myocardial infarction	3	[P35354, P11712, P23219]	DRUG	0.003646728
C02KX01	bosentan	C0006266	bronchospasm	1	[P24530]	DRUG_AND_METABOLITE	0.105539171
N06AB08	fluvoxamine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.001965274
N06AB04	citalopram	C0029456	osteoporosis	1	[P08684]	DRUG	0.147696203
M03BX01	baclofen	C0004134	ataxia	1	[P35498]	DRUG	0.083416405
S01EE03	bimatoprost	C0015230	rash	2	[P21731, Q13258]	DRUG_AND_METABOLITE	0.020237105
A10BB09	gliclazide	C0011603	dermatitis	1	[P15692]	DRUG	0.089912296
M01AE09	flurbiprofen	C0032285	pneumonia	2	[P10145, P35354]	DRUG_AND_METABOLITE	0.026888854
N04BD01	selegiline	C0025202	melanoma	2	[Q16853, P08183]	DRUG	0.426566789
L04AX04	lenalidomide	C0002390	allergic alveolitis	1	[P01375]	DRUG	0.098169818
C02CA04	doxazosin	C1527304	allergic reaction	1	[Q9H3N8]	METABOLITE	0.069093062
N01AH01	fentanyl	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.03451781
N02CC01	sumatriptan	C0042109	urticaria	1	[P07550]	DRUG	0.088180739
H02AB06	prednisolone	C0009951	convulsions	1	[P08183]	DRUG_AND_METABOLITE	0.19472871
J01FA09	clarithromycin	C0032584	polyps	5	[P05177, P08183, Q12809, P33527, P20815]	DRUG_AND_METABOLITE	0.082415968
J02AC02	itraconazole	C0020433	bilirubinemia	1	[P21439]	DRUG_AND_METABOLITE	0.030183251
C01BD01	amiodarone	C0002874	aplastic anemia	1	[P04798]	DRUG	0.128073342
M01AE02	naproxen	C0020456	hyperglycemia	1	[P35354]	DRUG	0.18451693
P02CA01	mebendazole	C0009951	convulsions	1	[P08183]	DRUG	0.096195732
C08CA05	nifedipine	C0018790	cardiac arrest	5	[Q12809, Q08289, P54289, Q13936, P18089]	DRUG	6.16908E-06
J05AE03	ritonavir	C0035078	renal failure	1	[P08183]	DRUG	0.089658424
C07AB04	acebutolol	C0001824	agranulocytosis	1	[P08183]	DRUG	0.030408848
C10AB05	fenofibrate	C0023890	cirrhosis	2	[P08684, P37231]	DRUG_AND_METABOLITE	0.02229004
N02CC01	sumatriptan	C0019080	hemorrhage	1	[P11712]	METABOLITE	0.118450023
N07CA01	betahistine	C0020517	hypersensitivity	2	[P35367, Q9H3N8]	METABOLITE	0.001434055
N05AA01	chlorpromazine	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.206353335
N06AB06	sertraline	C0001824	agranulocytosis	1	[P08183]	DRUG	0.07797371
A07EA06	budesonide	C0031350	Pharyngitis	1	[P05113]	DRUG	0.058976887
G03DA04	progesterone	C0037763	spasm	3	[P18507, P14867, P28472]	METABOLITE	0.001734938
L01BC06	capecitabine	C0024236	lymphedema	1	[P11509]	METABOLITE	0.033737522
N06AX16	venlafaxine	C0575081	abnormal gait	2	[P35498, Q12791]	DRUG	0.012792437
N06AA21	maprotiline	C0009806	constipation	1	[P31645]	DRUG_AND_METABOLITE	0.030408848
M01AE12	oxaprozin	C0027726	nephrotic syndrome	1	[P35354]	DRUG	0.086185333
J01MA01	ofloxacin	C0034065	pulmonary embolism	1	[P02768]	METABOLITE	0.033003054
C03CA01	furosemide	C0740394	hyperuricemia	1	[Q9NSA0]	DRUG	0.039009407
L02BG04	letrozole	C0030193	pain	1	[P11511]	DRUG	0.00976001
B01AC04	clopidogrel	C0013295	duodenal ulcer	1	[P33261]	DRUG	0.028561234
N02AA03	hydromorphone	C0006826	cancer	8	[P08183, P21964, P20815, P10632, P08684, P23219, Q12809, P23975]	METABOLITE	0.296659308
M01AE02	naproxen	C0019080	hemorrhage	1	[P11712]	DRUG	0.141091994
N05AB06	trifluoperazine	C0242422	Parkinson	14	[P21917, P05181, Q01959, P32238, P08183, P21554, P27338, P35354, P50406, P08908, P31645, Q9UQD0, P14416, P35462]	DRUG_AND_METABOLITE	3.52831E-05
N06AA02	imipramine	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.169036837
M01AC06	meloxicam	C0004096	asthma	3	[P09917, P35354, P23219]	DRUG_AND_METABOLITE	0.007256171
N04BC05	pramipexole	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.00011366
N06AB04	citalopram	C0038363	ulcerative stomatitis	1	[P31645]	DRUG	0.023338897
G03AC06	medroxyprogesterone	C0025202	melanoma	2	[P08183, P06401]	DRUG_AND_METABOLITE	0.105828833
N03AB02	phenytoin	C0035078	renal failure	1	[P08183]	DRUG	0.153656891
J05AE04	nelfinavir	C0026848	myopathy	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.10851061
P01BA01	chloroquine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.05490586
N06AX06	nefazodone	C0018524	hallucinations	1	[P08183]	DRUG	0.155750442
J01AA08	minocycline	C0030305	pancreatitis	2	[P01584, P15692]	DRUG	0.03423754
N02AD01	pentazocine	C0020538	hypertension	2	[P21728, Q9Y2I1]	DRUG	0.09415255
N06AB03	fluoxetine	C0018524	hallucinations	1	[P08183]	DRUG	0.176082284
C09CA01	losartan	C0039231	tachycardia	2	[P30556, P12821]	DRUG	0.001248928
N03AF02	oxcarbazepine	C0039231	tachycardia	1	[Q14524]	DRUG	0.016701405
N05AX08	risperidone	C0011206	delirium	2	[P32238, P21554]	DRUG_AND_METABOLITE	0.009279632
J01MA07	lomefloxacin	C0011991	diarrhea	1	[Q92887]	DRUG	0.028748417
G03AC06	medroxyprogesterone	C0025286	meningiomas	1	[P06401]	DRUG_AND_METABOLITE	0.080482871
R03AC13	formoterol	C0042109	urticaria	1	[P07550]	DRUG	0.025394378
A02BC01	omeprazole	C0151798	hepatic necrosis	1	[P08684]	DRUG_AND_METABOLITE	0.180499559
G03XC01	raloxifene	C0038454	cerebrovascular accident	1	[P03372]	DRUG	0.144630924
N03AB02	phenytoin	C0242184	hypoxia	3	[Q14432, Q14524, Q12809]	DRUG	0.129723858
C08CA05	nifedipine	C0018802	congestive heart failure	1	[Q12809]	DRUG	0.185493577
L01BA01	methotrexate	C0002871	anemia	1	[P02768]	DRUG	0.119381023
H05BX01	cinacalcet	C0009951	convulsions	1	[P31645]	DRUG	0.096195732
R03AC02	salbutamol	C0011849	diabetes mellitus	3	[P08684, P13945, P07550]	DRUG	0.000794668
N06AA17	amoxapine	C0038454	cerebrovascular accident	2	[P28223, P07550]	METABOLITE	0.126867639
G04BE09	vardenafil	C0007859	neck pain	1	[Q08499]	DRUG	0.022436068
G04BE03	sildenafil	C0007820	cerebrovascular disorder	1	[Q08499]	DRUG	0.273270497
C07AA03	pindolol	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.001179858
M01AB02	sulindac	C0009951	convulsions	2	[P35354, P49768]	METABOLITE	0.045203907
J01AA07	tetracycline	C0015230	rash	2	[P08254, P08253]	DRUG_AND_METABOLITE	0.046586487
A04AA01	ondansetron	C0023895	liver disease	1	[P08684]	DRUG	0.31133239
A04AA01	ondansetron	C0009806	constipation	3	[A5X5Y0, P46098, P41595]	DRUG	0.000398777
C10AA02	lovastatin	C0042029	urinary tract infection	1	[P30838]	METABOLITE	0.179767999
M01AE02	naproxen	C0020538	hypertension	10	[P35348, P21728, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089, P03952]	DRUG	0.000384154
M01AE02	naproxen	C0020542	pulmonary hypertension	2	[P35354, P31645]	DRUG	0.046224334
M01AH03	valdecoxib	C0026266	mitral insufficiency	4	[P23219, P31645, P35354, P11712]	DRUG_AND_METABOLITE	0.030786213
A02BC04	rabeprazole	C0027651	tumor	10	[Q9UNQ0, P04798, Q16678, P08684, P35354, P08183, P05177, P10632, P23219, P33261]	DRUG_AND_METABOLITE	0.499995859
M01AH01	celecoxib	C0015672	fatigue	3	[P31645, P28223, P35354]	DRUG_AND_METABOLITE	0.000443312
D07AC13	mometasone	C0021311	infection	1	[P04150]	METABOLITE	0.127583335
N04BC05	pramipexole	C0038363	ulcerative stomatitis	1	[P31645]	DRUG	0.031415297
L01BA01	methotrexate	C0037928	spinal cord disease	1	[P42898]	DRUG	0.06259756
J05AF04	stavudine	C0024115	lung disorder	1	[P05177]	METABOLITE	0.288374738
N05BC01	meprobamate	C0020517	hypersensitivity	6	[P42898, Q01959, P50135, P35367, P25021, Q9H3N8]	METABOLITE	0.000875659
M01AE02	naproxen	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.018603713
J02AC03	voriconazole	C0038358	gastric ulcer	1	[P23219]	DRUG	0.035028221
C02CA01	prazosin	C0042024	urinary incontinence	2	[P28223, P21917]	DRUG	0.007806911
C03CA01	furosemide	C0271650	latent diabetes	1	[P28845]	DRUG	0.093159412
C10AX09	ezetimibe	C0021311	infection	1	[P15144]	DRUG	0.225075103
A04AD12	aprepitant	C0020538	hypertension	2	[P20815, P11712]	DRUG_AND_METABOLITE	0.028748417
J05AE03	ritonavir	C0008311	cholangitis	1	[P21439]	DRUG	0.037934867
A02BC03	lansoprazole	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.108816906
L01XX35	anagrelide	C0009806	constipation	1	[P46098]	METABOLITE	0.022436068
M01AB08	etodolac	C0030920	peptic ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.004490873
C10AB05	fenofibrate	C0015695	liver fatty	2	[P37231, Q07869]	DRUG_AND_METABOLITE	0.004960489
L01AA01	cyclophosphamide	C0023530	leukopenia	1	[P08183]	DRUG	0.051010927
N04BD01	selegiline	C0018790	cardiac arrest	1	[P18089]	METABOLITE	0.085892844
C02CA01	prazosin	C1527304	allergic reaction	3	[P41595, P35367, Q9H3N8]	METABOLITE	0.003004332
N06DX01	memantine	C0085584	encephalopathy	1	[P22303]	DRUG	0.082129915
N05AX12	aripiprazole	C0020473	hyperlipidemia	1	[P07550]	DRUG_AND_METABOLITE	0.217660581
N06AA02	imipramine	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.128073342
A03FA02	cisapride	C0009806	constipation	3	[A5X5Y0, P46098, P41595]	DRUG	8.83767E-05
N06DA03	rivastigmine	C0015230	rash	1	[P31645]	DRUG	0.086440059
N05AX08	risperidone	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG_AND_METABOLITE	0.001041147
L04AX02	thalidomide	C0023418	leukemia	10	[P19838, P20815, P42263, P04798, P01375, P35354, Q08499, Q07343, P27815, P21980]	METABOLITE	0.161729114
N04BC02	pergolide	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.064088815
M01AB05	diclofenac	C0699893	skin carcinoma	9	[P10145, P35354, P42330, Q16790, P05181, P23219, P04798, P21554, P34972]	DRUG	0.045409295
N04BC05	pramipexole	C0149931	migraine	4	[P28223, P21917, P31645, P28335]	DRUG	0.000327066
C01BC04	flecainide	C0009806	constipation	1	[Q14524]	DRUG	0.019239124
L04AX02	thalidomide	C0023473	chronic myeloid leukemia	6	[P19838, P20815, P42263, P04798, P01375, P21980]	METABOLITE	0.335629767
G04CA02	tamsulosin	C0004093	asthenia	1	[P35354]	METABOLITE	0.039002635
H02AB02	dexamethasone	C0151514	skin atrophy	2	[P35354, P03956]	METABOLITE	0.101626316
C01BD01	amiodarone	C0019080	hemorrhage	1	[P11712]	DRUG	0.077866045
N05CF02	zolpidem	C0013395	Dyspepsia	1	[P23219]	DRUG	0.031289625
N03AF02	oxcarbazepine	C0009806	constipation	1	[Q14524]	DRUG	0.018096702
N04BC05	pramipexole	C0005747	blepharospasm	2	[P21918, P14416]	DRUG	0.016043482
A02BC03	lansoprazole	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.076200799
C09AA09	fosinopril	C0085096	peripheral vascular disorder	1	[P12821]	DRUG	0.03127
A03FA02	cisapride	C0242422	Parkinson	3	[P50406, P08908, P14416]	DRUG	0.043339606
N03AG01	valproic acid	C0013395	Dyspepsia	1	[P23219]	DRUG	0.046560113
D01AC02	miconazole	C0041912	upper respiratory tract infection	3	[P35228, P35354, P09601]	DRUG	0.345517289
C09AA08	cilazapril	C0035078	renal failure	2	[P12821, P08183]	DRUG	0.001208821
G02CB01	bromocriptine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000245734
L01CB01	etoposide	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.09523719
C09AA05	ramipril	C0006266	bronchospasm	1	[P12821]	DRUG	0.077274451
C04AD03	pentoxifylline	C0021400	Influenza	1	[P01375]	DRUG_AND_METABOLITE	0.047808761
M01AE01	ibuprofen	C0030305	pancreatitis	2	[P00918, P35354]	DRUG	0.144458057
M01AH02	rofecoxib	C0041912	upper respiratory tract infection	4	[P03973, P35354, P23219, P09917]	DRUG_AND_METABOLITE	0.246370433
L04AX04	lenalidomide	C0002103	allergic rhinitis	2	[P11712, P01375]	DRUG	0.020862332
C07AA03	pindolol	C0011991	diarrhea	1	[P46098]	DRUG	0.047754707
G03BA03	testosterone	C0030794	pelvic pain	1	[P11511]	DRUG_AND_METABOLITE	0.063987683
D05BB02	acitretin	C0011603	dermatitis	2	[P21731, Q13258]	METABOLITE	0.098137931
N05BA01	diazepam	C0023530	leukopenia	1	[P08183]	DRUG	0.114516617
N05AB06	trifluoperazine	C0018681	headache	2	[P05362, P29475]	DRUG	0.036670064
N02CC07	frovatriptan	C0015230	rash	1	[P08908]	DRUG	0.060210992
J02AC03	voriconazole	C0027051	myocardial infarction	3	[P11712, P33261, P23219]	DRUG	0.015087595
M01AE03	ketoprofen	C0027051	myocardial infarction	5	[P35354, P10145, P02768, P11712, P23219]	DRUG	0.001986914
C01BC03	propafenone	C0428977	bradycardia	1	[Q14524]	DRUG	0.012792437
N05AX12	aripiprazole	C0151744	myocardial ischemia	3	[P07550, P08588, Q12809]	DRUG_AND_METABOLITE	0.010478454
N01AX03	ketamine	C0014544	epilepsy	1	[P08183]	DRUG	0.10558648
N05AC02	thioridazine	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG_AND_METABOLITE	7.29447E-05
N04BD01	selegiline	C0018944	hematoma	1	[P11712]	DRUG_AND_METABOLITE	0.100645764
N04BC05	pramipexole	C0005697	neurogenic bladder	2	[P08172, P28223]	DRUG	0.00486818
C02CA04	doxazosin	C0042769	viral infection	1	[P04818]	METABOLITE	0.06555312
C07AB04	acebutolol	C0013604	edema	1	[P08588]	DRUG	0.01690995
C09CA07	telmisartan	C0021311	infection	3	[Q96RI1, P37231, Q07869]	DRUG	0.056270313
N02CC01	sumatriptan	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.171666695
L04AA06	mycophenolic acid	C0021311	infection	1	[P37231]	DRUG_AND_METABOLITE	0.180184941
G03BA03	testosterone	C0600139	prostate cancer	31	[P08183, P06401, P03372, Q92731, P11474, P42330, Q9UNQ0, P05093, P20815, P10632, P04798, P18405, P08684, P10275, P11511, P05177, Q16678, Q9HB55, P37058, P14061, P14060, P04278, O75751, P31213, P50225, P08842, P05108, P33261, P20813, P19793, Q12791]	METABOLITE	0.009768648
G03AC06	medroxyprogesterone	C0042487	venous thrombosis	1	[P03372]	DRUG_AND_METABOLITE	0.056501401
C10AB05	fenofibrate	C0011603	dermatitis	4	[P37231, Q9Y5Y4, Q13258, Q07869]	DRUG_AND_METABOLITE	0.000903387
P01AX06	atovaquone	C0013395	Dyspepsia	1	[P21964]	METABOLITE	0.093502489
A01AC01	triamcinolone	C0021311	infection	1	[P04150]	DRUG	0.127583335
N06AA17	amoxapine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.48976E-07
N04BD01	selegiline	C0029456	osteoporosis	1	[P08684]	DRUG_AND_METABOLITE	0.200806713
M01AE09	flurbiprofen	C0243026	sepsis	1	[P10145]	DRUG	0.166846606
M01AH02	rofecoxib	C0018524	hallucinations	1	[P33527]	DRUG_AND_METABOLITE	0.173681145
M01AB05	diclofenac	C0030920	peptic ulcer	4	[P35354, P10145, P33261, P23219]	DRUG_AND_METABOLITE	0.000797623
C08CA05	nifedipine	C0018681	headache	1	[O00555]	DRUG	0.07347151
M01AE02	naproxen	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG	5.17627E-07
J02AC02	itraconazole	C0020538	hypertension	1	[P20815]	DRUG_AND_METABOLITE	0.18054561
N05BA01	diazepam	C0035078	renal failure	1	[P08183]	DRUG	0.162841302
R03AC03	terbutaline	C0039231	tachycardia	2	[P07550, P08588]	DRUG	9.09152E-05
N05BA01	diazepam	C0027947	neutropenia	1	[P08183]	DRUG	0.09523719
G03CA03	estradiol	C0042487	venous thrombosis	3	[P03372, P21964, Q92731]	DRUG_AND_METABOLITE	0.024923189
A10BB09	gliclazide	C0027051	myocardial infarction	4	[P02768, P15692, P11712, P33261]	DRUG	0.000112498
N05AG02	pimozide	C0014130	Endocrine Disorders	3	[O95259, Q12809, P04798]	DRUG	0.193456647
J02AC02	itraconazole	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.063064427
N06AX16	venlafaxine	C0036572	seizures	2	[Q99250, P35498]	METABOLITE	0.030267383
C09AA04	perindopril	C0027947	neutropenia	1	[P08183]	DRUG	0.019687894
N06AB04	citalopram	C0038454	cerebrovascular accident	1	[P28223]	DRUG	0.202669364
M01AH02	rofecoxib	C0021311	infection	4	[P03973, P35354, P23219, P09917]	DRUG_AND_METABOLITE	0.281991681
N05AH04	quetiapine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000305005
N06AB06	sertraline	C0232726	tenesmus	1	[P11511]	METABOLITE	0.131507778
M01AH03	valdecoxib	C0042024	urinary incontinence	2	[P08172, P28223]	DRUG_AND_METABOLITE	0.010478454
A07EC04	balsalazide	C0030305	pancreatitis	2	[Q99895, P35354]	DRUG_AND_METABOLITE	0.016280057
N02AB02	meperidine	C0009951	convulsions	2	[P36544, P31645]	DRUG_AND_METABOLITE	0.055330287
D06BB10	imiquimod	C0042769	viral infection	1	[Q9NR97]	DRUG	0.023338897
N05AX08	risperidone	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.105027437
N05BA06	lorazepam	C0009951	convulsions	3	[P18507, P28472, P47870]	DRUG_AND_METABOLITE	0.012425662
G03CA03	estradiol	C0019360	herpes zoster	1	[P03372]	DRUG_AND_METABOLITE	0.061499211
N06AB08	fluvoxamine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.001965274
A07EA06	budesonide	C0015672	fatigue	4	[P08185, P35354, P04150, P35228]	METABOLITE	3.83447E-06
L01AX03	temozolomide	C0006826	cancer	5	[P05181, P04798, P08684, P05177, P00519]	DRUG	0.033976159
N01AX03	ketamine	C0018524	hallucinations	1	[P08183]	DRUG	0.091808164
C09AA01	captopril	C0038454	cerebrovascular accident	3	[P12821, P00734, P08253]	DRUG	0.010041031
M01AC06	meloxicam	C0740401	perforated duodenal ulcer	1	[P35354]	DRUG_AND_METABOLITE	0.029823411
M01AC01	piroxicam	C0018834	heartburn	1	[P23219]	DRUG_AND_METABOLITE	0.015405718
R03AC12	salmeterol	C0015230	rash	1	[P07550]	DRUG	0.086440059
B01AC05	ticlopidine	C0019158	hepatitis	3	[P05181, P23219, P35354]	DRUG_AND_METABOLITE	0.002988738
A04AD12	aprepitant	C0032584	polyps	2	[P05177, P20815]	DRUG_AND_METABOLITE	0.172473809
C02CA04	doxazosin	C0042024	urinary incontinence	1	[P28223]	METABOLITE	0.040753047
N02CC01	sumatriptan	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.0483478
N03AF01	carbamazepine	C0023530	leukopenia	1	[P08183]	DRUG	0.085235597
N06AA06	trimipramine	C0038454	cerebrovascular accident	3	[P05362, P28223, P07550]	DRUG_AND_METABOLITE	0.204160347
L02BB03	bicalutamide	C0243026	sepsis	1	[P04150]	DRUG	0.053332694
C09AA04	perindopril	C0042373	Vascular Disorders	1	[P12821]	DRUG_AND_METABOLITE	0.039025321
L02BG01	aminoglutethimide	C0006826	cancer	4	[P05093, P08684, P11511, P05177]	DRUG	0.103194236
J02AC01	fluconazole	C0006826	cancer	4	[P08183, P20815, P08684, P09601]	DRUG	0.125729421
N05AX08	risperidone	C0011603	dermatitis	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG_AND_METABOLITE	0.01440294
M01AE09	flurbiprofen	C0162316	iron deficiency anemia	3	[P10145, P02768, P07148]	DRUG	0.002413065
N06AB05	paroxetine	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.003713939
N06AB05	paroxetine	C0004096	asthma	2	[P11229, P20309]	DRUG	0.195796817
V03AH01	diazoxide	C0151744	myocardial ischemia	2	[P07550, P08588]	DRUG	0.005809415
L02BG04	letrozole	C0024236	lymphedema	2	[P11509, P08684]	DRUG	6.31065E-05
R03DC01	zafirlukast	C0015230	rash	6	[P47712, P07550, P37231, P28223, P08908, Q9Y271]	DRUG_AND_METABOLITE	0.001849681
C07AA07	sotalol	C0020473	hyperlipidemia	1	[P07550]	DRUG	0.067929039
G03DA04	progesterone	C0026848	myopathy	2	[P10275, Q9Y6L6]	METABOLITE	0.16513393
L04AX02	thalidomide	C0013595	eczema	1	[P01375]	DRUG	0.439336515
D05BB02	acitretin	C0015672	fatigue	1	[P35354]	METABOLITE	0.039806384
G03CA03	estradiol	C0015672	fatigue	1	[P08185]	DRUG_AND_METABOLITE	0.085892844
C07AB04	acebutolol	C0006266	bronchospasm	1	[P07550]	DRUG	0.144785429
L02BA02	toremifene	C0017601	glaucoma	1	[Q16678]	METABOLITE	0.1628433
N05AX08	risperidone	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000305005
J05AE03	ritonavir	C0022116	ischemia	1	[P05181]	DRUG	0.100457094
N02AB02	meperidine	C0009806	constipation	1	[P31645]	DRUG_AND_METABOLITE	0.034147949
N01BB09	ropivacaine	C0020538	hypertension	3	[P20815, P22460, P11712]	METABOLITE	0.069023604
N05AB02	fluphenazine	C0035078	renal failure	1	[P08183]	DRUG	0.146540748
N06AA02	imipramine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.142528506
J01MA01	ofloxacin	C0027651	tumor	7	[P08684, P11388, P08183, Q92887, P33527, P05177, Q12809]	DRUG_AND_METABOLITE	0.300526911
C09AA10	trandolapril	C0003811	arrhythmia	1	[P12821]	DRUG_AND_METABOLITE	0.013961737
B01AC07	dipyridamole	C0024902	breast pain	1	[Q08499]	DRUG	0.016169699
C07AA12	nadolol	C0018524	hallucinations	1	[P08183]	DRUG	0.038508848
M01AB15	ketorolac	C0008031	chest pain	1	[P02768]	DRUG	0.015087595
N06AA02	imipramine	C0003123	anorexia	9	[P28223, P21917, P28335, P21397, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	3.39333E-07
C02CA01	prazosin	C0027404	Narcolepsy	2	[Q99250, P35498]	DRUG	0.019460121
N05AE04	ziprasidone	C0024236	lymphedema	1	[P08684]	DRUG	0.058255985
N05AH02	clozapine	C0497327	dementia	3	[P08908, P31645, P17787]	DRUG	0.159178855
N04BC05	pramipexole	C0030354	papilloma	1	[P23975]	DRUG	0.499995859
J01XE01	nitrofurantoin	C0019158	hepatitis	1	[P05181]	DRUG	0.028717627
L04AX02	thalidomide	C0031099	periodontitis	2	[P04798, P01375]	DRUG	0.059602896
B01AC05	ticlopidine	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.07985866
L04AX02	thalidomide	C0231528	myalgia	1	[Q08499]	DRUG	0.295225154
C09AA01	captopril	C0038325	Stevens - Johnson syndrome	2	[P08253, P14780]	DRUG	0.000516726
M01AB08	etodolac	C0001824	agranulocytosis	2	[P16662, O60656]	DRUG	0.002408295
C03DB02	triamterene	C0020517	hypersensitivity	1	[O60674]	DRUG	0.055850064
N03AB02	phenytoin	C0149931	migraine	2	[P35498, P08684]	DRUG	0.026888854
C02CA04	doxazosin	C0015230	rash	2	[P28223, P08908]	METABOLITE	0.049355201
N05CF02	zolpidem	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.051680751
R03DA04	theophylline	C0021311	infection	3	[P01375, P21817, P47989]	METABOLITE	0.47325408
H02AB06	prednisolone	C0011849	diabetes mellitus	3	[P08684, P10632, P04278]	DRUG_AND_METABOLITE	0.051010353
N05AA01	chlorpromazine	C0037763	spasm	2	[P14867, P21918]	DRUG_AND_METABOLITE	0.029913007
C09AA03	lisinopril	C0021311	infection	2	[Q9BYF1, P12821]	DRUG	0.034852775
N05CF02	zolpidem	C0017152	gastritis	1	[P23219]	DRUG	0.084103037
D05BB02	acitretin	C0027051	myocardial infarction	4	[P35354, P02768, P43116, P23219]	METABOLITE	0.024401265
C01BC03	propafenone	C0019080	hemorrhage	1	[P11712]	DRUG	0.052118018
N03AX09	lamotrigine	C1458155	breast neoplasm	4	[P08183, Q99720, Q14524, Q12809]	DRUG	0.286739714
M01AB15	ketorolac	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.001184871
G04CA02	tamsulosin	C0009443	common cold	3	[Q9BPW9, P35354, P23219]	METABOLITE	0.139141851
J05AE03	ritonavir	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.037934867
N02CC01	sumatriptan	C0042487	venous thrombosis	2	[P03372, Q92731]	METABOLITE	0.042804682
A02BC02	pantoprazole	C0013390	dysmenorrhea	1	[P04798]	METABOLITE	0.019381901
N06AA04	clomipramine	C0033975	psychosis	8	[P35462, P28223, P21917, Q13639, P21397, P28222, P31645, P08908]	DRUG_AND_METABOLITE	2.66666E-05
L02BA02	toremifene	C0023530	leukopenia	2	[Q92887, P08183]	DRUG_AND_METABOLITE	0.041004597
L04AX02	thalidomide	C0013384	dyskinesia	2	[Q99259, P14416]	METABOLITE	0.092356341
L04AX02	thalidomide	C0013390	dysmenorrhea	2	[P35354, P04798]	DRUG	0.002988738
N07BA01	nicotine	C0149931	migraine	1	[P08684]	DRUG	0.128103215
L04AX02	thalidomide	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.084103037
N05AX08	risperidone	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.009279632
A03FA03	domperidone	C0011991	diarrhea	1	[P46098]	DRUG	0.045203907
N05AX08	risperidone	C0004096	asthma	5	[P07550, Q9Y271, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.062228737
N02CC04	rizatriptan	C0009806	constipation	3	[A5X5Y0, P46098, P41595]	METABOLITE	8.20217E-06
N01BB09	ropivacaine	C0018944	hematoma	1	[P11712]	METABOLITE	0.081354349
M01AB05	diclofenac	C0017152	gastritis	3	[P10145, P23219, P35354]	DRUG_AND_METABOLITE	0.007907224
D07AC04	fluocinolone acetonide	C0015230	rash	1	[P47712]	DRUG	0.050449029
N03AG01	valproic acid	C0013404	dyspnea	1	[P13726]	DRUG	0.082093178
H02AB02	dexamethasone	C0030305	pancreatitis	3	[P05181, P04798, P35354]	DRUG_AND_METABOLITE	0.017037273
N06BA04	methylphenidate	C0027651	tumor	5	[Q99720, Q01959, Q13639, P23975, P35348]	DRUG_AND_METABOLITE	0.499995859
N03AX09	lamotrigine	C0004134	ataxia	1	[P35498]	DRUG	0.061166635
N05AB06	trifluoperazine	C0018790	cardiac arrest	4	[Q12809, Q13936, P18089, P07550]	DRUG_AND_METABOLITE	0.002840837
C03DB01	amiloride	C0011991	diarrhea	2	[P46098, P37088]	DRUG	0.009015685
C10AB05	fenofibrate	C0015230	rash	4	[P37231, Q9Y5Y4, Q13258, Q07869]	DRUG_AND_METABOLITE	0.000286831
M01AB15	ketorolac	C0009324	ulcerative colitis	2	[P10145, P35354]	DRUG	0.040753047
N05AX08	risperidone	C0009951	convulsions	5	[Q9UBS5, P08183, P36544, P08908, P31645]	DRUG_AND_METABOLITE	0.010348691
N06AX16	venlafaxine	C0151827	eye pain	1	[O60840]	METABOLITE	0.09505443
C07AG02	carvedilol	C0009951	convulsions	3	[P08183, P08908, P31645]	DRUG_AND_METABOLITE	0.013399503
N05CF01	zopiclone	C0001969	drunk	2	[P47869, P05181]	DRUG	0.006482837
L01XE03	erlotinib	C0149871	deep vein thrombosis	2	[O60674, O14757]	DRUG_AND_METABOLITE	0.281527267
M01AH01	celecoxib	C0015230	rash	3	[P28223, P08908, P31645]	DRUG	0.072470568
A02BC02	pantoprazole	C0020443	hypercholesterolemia	1	[Q9Y6L6]	DRUG	0.08498899
A02BC04	rabeprazole	C0004998	skin benign neoplasm	6	[P05177, P08183, P35354, Q9UNQ0, Q16678, P04798]	DRUG_AND_METABOLITE	0.41810029
C10AA01	simvastatin	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.051010927
N05AB02	fluphenazine	C0031511	pheochromocytoma	4	[P05177, P08183, P05181, P10275]	DRUG	0.466515826
A02BC02	pantoprazole	C0020433	bilirubinemia	1	[Q9Y6L6]	DRUG	0.052057421
N03AF02	oxcarbazepine	C0009951	convulsions	3	[P35498, Q99250, Q9NY46]	DRUG	0.00145582
C04AD03	pentoxifylline	C0021311	infection	1	[P01375]	DRUG_AND_METABOLITE	0.325990764
N05AD01	haloperidol	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.007694259
N05AX12	aripiprazole	C0028754	obesity	1	[P07550]	DRUG_AND_METABOLITE	0.204720971
G04BE03	sildenafil	C0007784	cerebral hemorrhage	1	[Q08499]	DRUG	0.237019021
N01BB09	ropivacaine	C0018790	cardiac arrest	3	[Q14524, Q12809, Q13936]	METABOLITE	0.000490405
A05AA02	ursodeoxycholic acid	C0030305	pancreatitis	1	[P05181]	DRUG_AND_METABOLITE	0.103777387
N06AA04	clomipramine	C0037763	spasm	2	[P14867, P21918]	DRUG_AND_METABOLITE	0.022498355
N06AX16	venlafaxine	C0001969	drunk	12	[P28223, P31645, P21728, P08908, P35462, P14416, P21397, P08172, Q05586, Q13224, P35372, P25103]	DRUG	0
C07AA05	propranolol	C0018790	cardiac arrest	2	[Q13936, P07550]	DRUG_AND_METABOLITE	0.011832432
C07AA05	propranolol	C0018799	heart disease	4	[P31645, P08588, P07550, P41595]	DRUG	0.028343005
N06AX05	trazodone	C0018802	congestive heart failure	2	[Q9Y2I1, P07550]	DRUG_AND_METABOLITE	0.071757865
N05AH03	olanzapine	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG_AND_METABOLITE	9.71969E-06
J01MA01	ofloxacin	C0027947	neutropenia	2	[Q92887, P08183]	DRUG	0.004222847
A02BA04	nizatidine	C0020517	hypersensitivity	3	[P35367, P25021, Q9H3N8]	DRUG	0.000723628
A10BB09	gliclazide	C0027651	tumor	2	[P15692, P33261]	DRUG	0.31590567
L04AA13	leflunomide	C0151798	hepatic necrosis	1	[P03956]	DRUG	0.099257725
N04BC04	ropinirole	C0003873	rheumatoid arthritis	2	[P05177, P07550]	DRUG	0.238732572
N06AA06	trimipramine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.001536633
N06AB03	fluoxetine	C0006266	bronchospasm	3	[P11229, P20309, Q08499]	METABOLITE	0.15591646
N05AH03	olanzapine	C1510472	drug dependence	1	[P41595]	DRUG_AND_METABOLITE	0.040204533
N05AX08	risperidone	C0011849	diabetes mellitus	3	[P08684, P18089, P07550]	DRUG_AND_METABOLITE	0.215112556
M01AB15	ketorolac	C0019080	hemorrhage	1	[P11712]	DRUG	0.0608928
N02AA03	hydromorphone	C0006266	bronchospasm	1	[P23219]	DRUG	0.369658864
N02CC01	sumatriptan	C0035078	renal failure	1	[P08183]	DRUG_AND_METABOLITE	0.164896017
N06AX06	nefazodone	C0018802	congestive heart failure	2	[Q9Y2I1, P07550]	METABOLITE	0.044555324
C07AA15	carteolol	C0015230	rash	1	[P07550]	DRUG	0.100741343
B05BC01	mannitol	C0021311	infection	21	[P29460, P17931, P49789, P10144, P11226, P06729, P11717, P01574, P27487, P13688, Q9NNX6, P15529, Q9BZZ2, P02788, P52799, P23219, P02749, P16410, Q9Y286, P35247, P01130]	METABOLITE	0.000286831
N06AX16	venlafaxine	C0029456	osteoporosis	2	[P08684, P34972]	METABOLITE	0.131427357
M01AH03	valdecoxib	C0030305	pancreatitis	2	[P00918, P35354]	DRUG_AND_METABOLITE	0.091730301
N05BE01	buspirone	C0027051	myocardial infarction	6	[P21554, P13945, P07550, P31645, P08588, P18089]	DRUG_AND_METABOLITE	0.057844321
N07XX02	riluzole	C0003873	rheumatoid arthritis	2	[P05177, P04798]	DRUG	0.123521484
N03AX09	lamotrigine	C0004238	atrial fibrillation	1	[Q14524]	DRUG	0.07026785
M01AB05	diclofenac	C0027813	neuritis	1	[P08183]	DRUG	0.129936284
C01BB01	lidocaine	C0006266	bronchospasm	2	[P00533, P16050]	METABOLITE	0.184397912
J01AA08	minocycline	C0002792	anaphylaxis	2	[P01584, P08253]	DRUG_AND_METABOLITE	0.007010373
M01AE03	ketoprofen	C0085096	peripheral vascular disorder	1	[P10145]	DRUG	0.095009391
H02AB06	prednisolone	C0030920	peptic ulcer	1	[P33261]	METABOLITE	0.082956716
C09AA01	captopril	C0022658	nephropathy	4	[Q9BYF1, P02768, P08253, P14780]	DRUG	0.000286831
L04AX01	azathioprine	C0024299	lymphoma	1	[P27361]	METABOLITE	0.449802927
N05BA01	diazepam	C0014549	grand mal	2	[Q99250, P35498]	DRUG	0.017780322
N05AD01	haloperidol	C0011991	diarrhea	2	[P46098, O60656]	DRUG	0.019656405
N06AB04	citalopram	C0033975	psychosis	5	[P35462, P28223, P28222, P31645, P08908]	DRUG	1.98074E-05
C10AA01	simvastatin	C0151798	hepatic necrosis	1	[P08684]	DRUG_AND_METABOLITE	0.104056627
J02AC03	voriconazole	C0038454	cerebrovascular accident	1	[P24557]	METABOLITE	0.107647419
G04BD04	oxybutynin	C0018799	heart disease	1	[Q12809]	DRUG	0.134412234
N06AX16	venlafaxine	C0040822	tremor	1	[Q14643]	DRUG	0.05451108
J05AE01	saquinavir	C0004096	asthma	1	[P33527]	DRUG	0.280349021
L02AB01	megestrol	C0021311	infection	2	[P03372, P04150]	DRUG	0.082956716
C07AA05	propranolol	C0018802	congestive heart failure	1	[P07550]	DRUG_AND_METABOLITE	0.153623294
C07AA05	propranolol	C0018801	heart failure	1	[P07550]	DRUG_AND_METABOLITE	0.153623294
N06AB04	citalopram	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.046530938
C07AG01	labetalol	C0006266	bronchospasm	1	[P07550]	DRUG	0.179324562
C10AA01	simvastatin	C0023890	cirrhosis	1	[P08684]	DRUG_AND_METABOLITE	0.12507432
G03DA04	progesterone	C0003123	anorexia	4	[P28223, P21397, P14416, P04278]	METABOLITE	0.003514924
P01AX06	atovaquone	C0021311	infection	7	[P09211, P07550, P42898, P49327, Q9UBC3, Q13363, P01024]	METABOLITE	0.456260126
C02CA04	doxazosin	C0015672	fatigue	1	[P28223]	METABOLITE	0.035047926
A10BX02	repaglinide	C0041912	upper respiratory tract infection	1	[P37231]	DRUG	0.210928081
N04BC05	pramipexole	C1458155	breast neoplasm	3	[Q99720, Q01959, P23975]	DRUG	0.499995859
N06AX16	venlafaxine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.136626787
N05AE04	ziprasidone	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.499499939
D01AE15	terbinafine	C0017152	gastritis	1	[P23219]	DRUG	0.06259756
M01AH03	valdecoxib	C0684249	lung cancer	7	[P35354, P33527, Q16790, P23219, P11712, P33261, P08684]	DRUG_AND_METABOLITE	0.121673094
A03FA01	metoclopramide	C0042024	urinary incontinence	1	[P28223]	DRUG	0.050945221
G03DA04	progesterone	C0010709	cyst	18	[P05177, P11509, P08183, P06401, P03372, P15531, Q92731, P33527, Q9UNQ0, P31213, P11511, P20815, P05181, Q16678, P08235, P18405, P04798, P10275]	DRUG_AND_METABOLITE	0.174370945
C01BC03	propafenone	C0024115	lung disorder	2	[P08183, P05177]	DRUG	0.050501715
C01BC03	propafenone	C0024117	COPD	1	[P05177]	DRUG	0.146088071
A02BC04	rabeprazole	C0027051	myocardial infarction	7	[P35354, P02768, P04798, P11712, P33261, P23219, P05177]	DRUG_AND_METABOLITE	0.007622355
A10BB07	glipizide	C0149931	migraine	1	[P08684]	DRUG	0.040753047
S01ED02	betaxolol	C0442874	neuropathy	2	[Q9UQD0, P08183]	METABOLITE	0.012780272
N07BC02	methadone	C0013146	abuse	1	[P41595]	METABOLITE	0.040557986
G04BE03	sildenafil	C0007642	cellulitis	1	[Q07343]	DRUG	0.173560749
N05AB06	trifluoperazine	C0020456	hyperglycemia	2	[P35354, Q9Y210]	METABOLITE	0.143199044
C04AD03	pentoxifylline	C0003123	anorexia	1	[P01375]	DRUG_AND_METABOLITE	0.054135291
C07AA03	pindolol	C0011570	mental depression	8	[P28223, P28335, P28222, P50406, P47898, P08908, P18825, P31645]	DRUG	0
C09CA02	eprosartan	C0035078	renal failure	1	[P30556]	DRUG	0.041794575
L04AX04	lenalidomide	C0006277	bronchitis	1	[P01375]	DRUG	0.027162705
N06DA03	rivastigmine	C0015672	fatigue	1	[P31645]	DRUG	0.017783546
S01ED03	levobunolol	C0042109	urticaria	1	[P07550]	DRUG	0.022963468
A07EA06	budesonide	C0015230	rash	1	[P05113]	DRUG	0.261800081
C09AA07	benazepril	C0003811	arrhythmia	1	[P12821]	DRUG_AND_METABOLITE	0.013961737
N06AX21	duloxetine	C0231528	myalgia	3	[P17252, P29475, Q8NER1]	DRUG	0.041540814
N05AB04	prochlorperazine	C1527304	allergic reaction	2	[Q01959, P35367]	DRUG	0.012112884
L01XE02	gefitinib	C0040034	thrombocytopenia	1	[O60674]	DRUG_AND_METABOLITE	0.327279171
C09CA01	losartan	C0023222	leg pain	1	[Q08499]	DRUG	0.019028106
N06BA04	methylphenidate	C0027430	nasal polyps	1	[P23975]	DRUG_AND_METABOLITE	0.499995859
J01MA01	ofloxacin	C0027720	nephrosis	1	[P02768]	METABOLITE	0.086440059
N06AB04	citalopram	C0031212	personality disorder	1	[P31645]	DRUG	0.023338897
N01BB09	ropivacaine	C0442874	neuropathy	2	[Q9UQD0, P08183]	METABOLITE	0.026625335
N02CC03	zolmitriptan	C1458155	breast neoplasm	1	[P05177]	DRUG	0.489795092
C02CA04	doxazosin	C0003123	anorexia	2	[P28223, P14416]	METABOLITE	0.00976001
N02AX02	tramadol	C0010709	cyst	1	[P23975]	DRUG_AND_METABOLITE	0.461784936
J01MA02	ciprofloxacin	C0035078	renal failure	1	[P08183]	DRUG	0.074465973
N02AC04	propoxyphene	C0009951	convulsions	1	[P31645]	METABOLITE	0.108919575
N06AX16	venlafaxine	C0011206	delirium	2	[P32238, P21554]	METABOLITE	0.012792437
N06DA02	donepezil	C0017152	gastritis	1	[P23219]	DRUG	0.052242123
A02BC03	lansoprazole	C0030305	pancreatitis	2	[Q99895, P04798]	DRUG	0.037352227
L02BA01	tamoxifen	C0020473	hyperlipidemia	1	[P23219]	DRUG	0.160121456
L04AX02	thalidomide	C0034067	emphysema	1	[P21802]	DRUG	0.117247144
C01DA02	nitroglycerin	C0013595	eczema	1	[P09211]	METABOLITE	0.157752421
N06AA17	amoxapine	C0018524	hallucinations	1	[P36544]	METABOLITE	0.173681145
A10BG02	rosiglitazone	C0027051	myocardial infarction	6	[P37231, Q07869, P11712, P33261, P23219, P05177]	DRUG	0.000299598
L02BG03	anastrozole	C0006826	cancer	3	[P08684, P11511, P05177]	DRUG_AND_METABOLITE	0.208059347
C07AA05	propranolol	C0006266	bronchospasm	1	[P07550]	DRUG_AND_METABOLITE	0.382742428
C08DB01	diltiazem	C0009806	constipation	1	[P46098]	DRUG	0.037934867
N04BC04	ropinirole	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.034424934
N06BA04	methylphenidate	C0004096	asthma	2	[P11229, P20309]	DRUG_AND_METABOLITE	0.212536646
N06BA04	methylphenidate	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.004167423
N02CC03	zolmitriptan	C0678222	breast cancer	1	[P05177]	DRUG	0.485850957
A10BX03	nateglinide	C0011991	diarrhea	1	[O60656]	DRUG_AND_METABOLITE	0.033737522
N05AX12	aripiprazole	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.102103327
N06AA11	protriptyline	C0038454	cerebrovascular accident	3	[P05362, P28223, P07550]	DRUG	0.082956716
N06AX05	trazodone	C0018524	hallucinations	1	[P08183]	DRUG	0.205488636
C09AA13	moexipril	C0042109	urticaria	1	[P12821]	DRUG_AND_METABOLITE	0.020490582
N05BA02	chlordiazepoxide	C0022346	jaundice	3	[Q9Y6L6, P22309, Q9NPD5]	DRUG	0.000156554
N03AF02	oxcarbazepine	C0015230	rash	1	[Q16548]	DRUG	0.100741343
R03AC02	salbutamol	C0015230	rash	1	[P07550]	DRUG	0.060210992
G02CB03	cabergoline	C0020517	hypersensitivity	2	[P41595, P35367]	DRUG	0.014503926
N01BB09	ropivacaine	C0027051	myocardial infarction	3	[P11712, P33261, P05177]	DRUG_AND_METABOLITE	0.086440059
N02AB02	meperidine	C0018524	hallucinations	1	[P36544]	DRUG_AND_METABOLITE	0.105027437
P02CA03	albendazole	C0002874	aplastic anemia	1	[P04798]	DRUG	0.074465973
C01EB03	indomethacin	C0020538	hypertension	3	[P37231, P25101, P11712]	DRUG	0.163180596
L02BA01	tamoxifen	C0020538	hypertension	6	[P20815, P03372, P11511, P11712, P31513, Q92731]	DRUG_AND_METABOLITE	0.006194122
L02AB01	megestrol	C0007286	carpal tunnel syndrome	2	[P06401, P03372]	DRUG	0.000112117
C01EB03	indomethacin	C0020542	pulmonary hypertension	2	[P37231, P35354]	DRUG_AND_METABOLITE	0.037703475
M03BX02	tizanidine	C0007097	carcinoma	1	[P05177]	DRUG	0.422369873
M05BA04	alendronate	C0021311	infection	2	[P42336, P48736]	DRUG	0.14501301
N06AA06	trimipramine	C0015230	rash	6	[P07550, P28223, P08908, P31645, P17405, P09211]	DRUG	0.035812138
L01CB01	etoposide	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.039009407
N01AH01	fentanyl	C0024236	lymphedema	1	[P08684]	DRUG	0.024401265
N05AH04	quetiapine	C0018802	congestive heart failure	3	[Q9Y2I1, Q12809, P07550]	DRUG	0.021209641
R06AX02	cyproheptadine	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
G04BE03	sildenafil	C0011603	dermatitis	1	[Q07343]	DRUG	0.318014397
L01BA01	methotrexate	C0027947	neutropenia	3	[Q92887, Q9NPD5, P08183]	DRUG	0.000673189
N06AF03	phenelzine	C0015230	rash	2	[P31645, P23946]	METABOLITE	0.049355201
L01XE02	gefitinib	C0027651	tumor	124	[P31749, P42336, Q9UNQ0, P07333, P08684, P00533, P04626, P21802, P11309, P08183, P46734, Q9UK32, P35968, Q14289, P37173, P36897, P10721, Q14164, Q15746, Q9Y243, O60674, Q15303, P22455, P68400, P28482, P22607, P27361, P45985, P41240, Q16539, P29317, Q08345, P43405, P08069, P49137, Q13153, P08581, P51813, P07949, O14965, P12931, P42685, P50750, P24941, P16234, Q13177, Q96GD4, Q13873, P07948, Q05397, Q15831, P07947, Q07912, Q13882, P17948, P60953, P31751, P00519, P68366, P45984, Q15418, Q15349, Q9UKI8, P17612, P06239, Q02156, Q05655, P53667, P11362, P45983, Q13164, Q04759, P48730, P49674, P49841, P51812, Q9UIK4, Q15375, Q02763, P53350, P51955, Q9P289, P09619, O75582, P15056, Q92918, P43403, P53355, P50613, O43293, Q16832, P04629, P35916, O14757, P54762, P54760, P07332, Q9UM73, P52333, P24723, P06213, P29597, P29323, P19525, P36894, Q00526, P06241, O95835, P21709, Q02750, P36507, P49840, Q9NRM7, P23458, Q16620, P22694, Q9NQU5, P16591, Q15139, P27037, P04049, Q00535, Q9P1W9, Q13546]	DRUG_AND_METABOLITE	0.029637746
M01AE01	ibuprofen	C0001122	acidosis	1	[Q16790]	METABOLITE	0.113271913
N06DA03	rivastigmine	C0011603	dermatitis	1	[P31645]	DRUG	0.110503219
L04AX04	lenalidomide	C0028259	nodule	1	[P01375]	DRUG	0.019239124
N06AA10	nortriptyline	C0001824	agranulocytosis	1	[P08183]	DRUG	0.122744
M01AB05	diclofenac	C0007097	carcinoma	14	[P05181, P35354, P08183, P33527, Q16790, P10145, P23219, P42330, P10632, P04798, Q9Y5N1, P08684, P05177, P22309]	DRUG	0.375658624
C09CA01	losartan	C0023530	leukopenia	3	[P16662, P22309, P08183]	DRUG	0.000714178
M04AA01	allopurinol	C0035078	renal failure	1	[P29274]	METABOLITE	0.243905676
M01AH03	valdecoxib	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.056501401
L02BA01	tamoxifen	C0162566	porphyria cutanea tarda	1	[P05177]	DRUG_AND_METABOLITE	0.038585711
N05AH02	clozapine	C0019158	hepatitis	2	[P05181, P11509]	DRUG	0.092356341
N05AA01	chlorpromazine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.002124178
R03BA08	ciclesonide	C0029456	osteoporosis	1	[P08684]	DRUG	0.049083824
N06AX21	duloxetine	C0021311	infection	7	[P07550, P04156, Q13936, P35354, P23219, P17252, P09917]	METABOLITE	0.36445538
N05CD02	nitrazepam	C0004134	ataxia	1	[P35498]	DRUG	0.167395635
D08AC02	chlorhexidine	C0013604	edema	1	[P14780]	DRUG	0.015405718
N01AH01	fentanyl	C0442874	neuropathy	1	[P08183]	DRUG	0.084103037
N06AF03	phenelzine	C0004134	ataxia	1	[P80404]	DRUG	0.076642524
C01BD01	amiodarone	C0018524	hallucinations	1	[P08183]	DRUG	0.107464244
C08DB01	diltiazem	C0009951	convulsions	5	[P35498, P08183, Q99250, Q9NY46, P08908]	DRUG	0.000593081
L04AX02	thalidomide	C0027051	myocardial infarction	12	[P35354, P48507, P21554, P00488, P01375, Q08499, P04798, P48506, P11712, P33261, P23219, P05177]	DRUG	0.006342878
N02AA05	oxycodone	C0018799	heart disease	1	[P31645]	DRUG	0.145004542
N03AE01	clonazepam	C0149931	migraine	1	[P08684]	DRUG	0.088180739
J05AE01	saquinavir	C0032584	polyps	5	[P08183, Q92887, P33527, Q9UNQ0, P20815]	DRUG	0.146298288
N06AA11	protriptyline	C0003123	anorexia	6	[P28223, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.54047E-05
M03BX08	cyclobenzaprine	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.186837916
N06AB08	fluvoxamine	C0024115	lung disorder	5	[P08183, P05181, P04798, P31645, P05177]	DRUG_AND_METABOLITE	0.001555998
L04AX02	thalidomide	C0231218	malaise	1	[Q08499]	DRUG	0.04898487
C01EB03	indomethacin	C0020456	hyperglycemia	3	[P37231, P35354, P10145]	DRUG	0.009737741
N06DA03	rivastigmine	C0027932	neurosis	1	[P31645]	DRUG	0.015405718
N04BD01	selegiline	C0030920	peptic ulcer	1	[P33261]	DRUG_AND_METABOLITE	0.114661067
N03AX16	pregabalin	C0005967	bone neoplasm	1	[Q01650]	DRUG	0.401674859
C09AA04	perindopril	C0042109	urticaria	1	[P12821]	DRUG_AND_METABOLITE	0.018096702
N02AX02	tramadol	C0009806	constipation	1	[P31645]	DRUG_AND_METABOLITE	0.023338897
C01BC03	propafenone	C0010054	coronary artery disease	1	[P08684]	DRUG	0.170421814
N06AB06	sertraline	C0018418	gynecomastia	1	[P11511]	METABOLITE	0.018096702
N01AH01	fentanyl	C0024115	lung disorder	1	[P08183]	DRUG	0.206353335
C07AA06	timolol	C0021311	infection	1	[P07550]	DRUG	0.311927901
N05AH03	olanzapine	C0008031	chest pain	1	[P02768]	DRUG	0.034021738
C08DB01	diltiazem	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.000305005
N03AX09	lamotrigine	C0020538	hypertension	1	[P11712]	DRUG	0.222055843
N06DA03	rivastigmine	C0004093	asthenia	1	[P31645]	DRUG	0.017783546
N06AA01	desipramine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.127182501
N06AB08	fluvoxamine	C0003873	rheumatoid arthritis	2	[P05177, P04798]	DRUG_AND_METABOLITE	0.195681252
C09CA07	telmisartan	C0006266	bronchospasm	1	[P37231]	DRUG	0.20086833
M01AE02	naproxen	C0002874	aplastic anemia	1	[P60953]	DRUG	0.239951985
M01AE02	naproxen	C0002871	anemia	1	[P02768]	DRUG	0.187538464
M01AE02	naproxen	C0002878	hemolytic anemia	1	[P22309]	DRUG	0.127602067
G03CA03	estradiol	C0013390	dysmenorrhea	1	[P04798]	DRUG_AND_METABOLITE	0.040229277
N05AA01	chlorpromazine	C0004096	asthma	12	[P07550, P09917, P05362, P47989, P35354, P23219, P43115, P29475, P11229, P29274, P20309, Q14643]	DRUG	0.01266617
G03CA03	estradiol	C0013395	Dyspepsia	1	[P21964]	DRUG	0.06803181
N04BC05	pramipexole	C0024117	COPD	2	[P07550, P31645]	DRUG	0.129792881
J05AG03	efavirenz	C0023798	lipoma	1	[P05177]	DRUG	0.418105216
N05AE04	ziprasidone	C0013604	edema	1	[P08588]	DRUG	0.063186267
C07AB02	metoprolol	C0006266	bronchospasm	1	[P07550]	DRUG_AND_METABOLITE	0.220108265
C09AA06	quinapril	C0027051	myocardial infarction	1	[P12821]	DRUG_AND_METABOLITE	0.085527439
L04AA06	mycophenolic acid	C0038358	gastric ulcer	1	[P37231]	DRUG_AND_METABOLITE	0.021227014
C07AG01	labetalol	C0042109	urticaria	1	[P07550]	DRUG	0.033976159
N07BC02	methadone	C0878544	cardiomyopathy	2	[Q12809, P08588]	METABOLITE	0.092935475
G04BE09	vardenafil	C0456909	blindness	1	[P35913]	DRUG	0.058976887
G04CA03	terazosin	C0015672	fatigue	1	[P28223]	DRUG_AND_METABOLITE	0.056501401
C10AB05	fenofibrate	C0085096	peripheral vascular disorder	1	[P37231]	DRUG_AND_METABOLITE	0.074019775
N06BA01	amphetamine	C0042769	viral infection	1	[P14174]	METABOLITE	0.187936819
N02CC01	sumatriptan	C0027051	myocardial infarction	11	[P02768, P03372, P13945, P04798, P10275, Q92731, P07550, P11712, P05177, P08588, P18089]	DRUG	3.98671E-05
N06AA04	clomipramine	C0019080	hemorrhage	1	[P11712]	DRUG	0.218495181
B01AC04	clopidogrel	C1458140	bleeding diathesis	1	[P11712]	DRUG	0.038827414
C09CA03	valsartan	C0035078	renal failure	1	[P30556]	DRUG	0.037532924
M04AB01	probenecid	C0027726	nephrotic syndrome	1	[P02768]	DRUG	0.242020171
M01AH03	valdecoxib	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.051665686
J01FA09	clarithromycin	C0009951	convulsions	2	[P08183, P33527]	DRUG	0.035667691
N04BD01	selegiline	C0019158	hepatitis	2	[P05181, P11509]	DRUG_AND_METABOLITE	0.04063245
M01AE12	oxaprozin	C0041912	upper respiratory tract infection	2	[P35354, P23219]	DRUG	0.051685285
N06AB05	paroxetine	C0009319	colitis	4	[P08183, P31645, P46098, P41595]	DRUG	0.01037023
C02KX01	bosentan	C0023890	cirrhosis	1	[P08684]	DRUG_AND_METABOLITE	0.064448325
N04BD01	selegiline	C0023530	leukopenia	1	[P08183]	DRUG	0.105422145
N06AX16	venlafaxine	C0039070	syncope	1	[P29274]	DRUG_AND_METABOLITE	0.074076931
N06AA11	protriptyline	C0015230	rash	5	[P07550, P28223, P08908, P31645, P17405]	DRUG	0.016169699
N06AX05	trazodone	C0018790	cardiac arrest	2	[P18089, P07550]	DRUG_AND_METABOLITE	0.022436068
N06AA04	clomipramine	C0003123	anorexia	9	[P28223, P21917, P28335, P21397, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.48976E-07
N06DA03	rivastigmine	C0027651	tumor	1	[P08684]	DRUG	0.485641202
R03DC01	zafirlukast	C0020517	hypersensitivity	2	[P41595, P35367]	DRUG_AND_METABOLITE	0.043503908
L04AX01	azathioprine	C0027651	tumor	20	[P11309, P06730, P17252, P27361, Q16539, P22309, P12931, P47989, P16220, Q13126, P06493, P60891, O15440, P51580, P15104, Q02750, P24666, P08238, Q08499, O15439]	METABOLITE	0.461446018
N05AX08	risperidone	C0006266	bronchospasm	5	[P07550, Q9Y271, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.062228737
L01XE03	erlotinib	C0032285	pneumonia	2	[P43405, P20783]	DRUG_AND_METABOLITE	0.333990256
C03CA01	furosemide	C0001339	acute pancreatitis	2	[Q99895, P00918]	DRUG_AND_METABOLITE	0.040568762
D07AC04	fluocinolone acetonide	C0020615	hypoglycemia	1	[P04150]	DRUG	0.019381901
N06AA06	trimipramine	C0231218	malaise	1	[Q8NER1]	METABOLITE	0.053008495
A02BC01	omeprazole	C0030193	pain	1	[Q8NER1]	DRUG	0.036486436
N02AB02	meperidine	C0018790	cardiac arrest	1	[Q12809]	DRUG_AND_METABOLITE	0.059501915
M04AA01	allopurinol	C0043144	wheezing	7	[P00533, P16220, P00813, P47989, P29274, Q08499, P12931]	METABOLITE	0.036564399
C07AA06	timolol	C0009443	common cold	1	[P07550]	DRUG	0.298579399
A02BC04	rabeprazole	C0017601	glaucoma	1	[Q16678]	METABOLITE	0.116972229
N02AX02	tramadol	C0009951	convulsions	1	[P31645]	DRUG_AND_METABOLITE	0.127783868
C02CA01	prazosin	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.001136894
N02AX02	tramadol	C0149931	migraine	3	[P31645, P08684, P28335]	DRUG	0.000258147
N05AE04	ziprasidone	C0013595	eczema	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG	0.002805827
C07AB07	bisoprolol	C0020615	hypoglycemia	1	[P07550]	DRUG_AND_METABOLITE	0.026665834
N06AX05	trazodone	C0152029	sinus congestion	3	[P25021, P35367, P08588]	DRUG_AND_METABOLITE	0.026969664
C09AA04	perindopril	C0038454	cerebrovascular accident	1	[P12821]	DRUG_AND_METABOLITE	0.05696568
N06DA03	rivastigmine	C0011849	diabetes mellitus	2	[P06276, P08684]	DRUG	0.028343005
A02BC02	pantoprazole	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.07797371
G03AC06	medroxyprogesterone	C0009951	convulsions	1	[P08183]	DRUG_AND_METABOLITE	0.102909805
C09CA06	candesartan	C0018802	congestive heart failure	2	[P30556, P50052]	DRUG_AND_METABOLITE	0.005587699
N05AD01	haloperidol	C0006266	bronchospasm	5	[P07550, P51681, P43115, P11229, P20309]	DRUG	0.105539171
C09AA03	lisinopril	C0015672	fatigue	1	[P12821]	DRUG	0.012425662
J01XD02	tinidazole	C0009806	constipation	1	[P41595]	DRUG	0.006405429
N02AC04	propoxyphene	C0009806	constipation	1	[P31645]	METABOLITE	0.02023865
M01AE02	naproxen	C0015672	fatigue	3	[P31645, P28223, P35354]	DRUG	0.000516726
C01BD01	amiodarone	C0018790	cardiac arrest	2	[Q14524, Q12809]	DRUG	0.006342878
N05AH03	olanzapine	C0031212	personality disorder	1	[P31645]	DRUG	0.040204533
N06AA02	imipramine	C0231218	malaise	1	[Q8NER1]	METABOLITE	0.053008495
G04BE03	sildenafil	C0011849	diabetes mellitus	2	[P11712, P08684]	DRUG	0.190102925
N04BC04	ropinirole	C0026266	mitral insufficiency	2	[P08588, P07550]	DRUG	0.082492612
N04BX01	tolcapone	C0442874	neuropathy	1	[P21964]	DRUG	0.070518569
N02AA05	oxycodone	C0006826	cancer	3	[P20815, P08684, P23975]	DRUG	0.208059347
N05AX12	aripiprazole	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG_AND_METABOLITE	0.000930987
N06AA12	doxepin	C0020538	hypertension	14	[P20815, P35348, P13945, P07550, P21728, O15244, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	0.000515691
M01AB05	diclofenac	C0015672	fatigue	2	[P28223, P35354]	DRUG_AND_METABOLITE	0.008292374
N04BC05	pramipexole	C0003850	arteriosclerosis	1	[P31645]	DRUG	0.435182503
N02CC01	sumatriptan	C0015672	fatigue	2	[P08185, P28223]	DRUG	0.006002348
N04BC05	pramipexole	C0003864	arthritis	1	[Q9H3N8]	DRUG	0.209388562
L01BC06	capecitabine	C0034065	pulmonary embolism	1	[P02768]	METABOLITE	0.041509351
N04BC05	pramipexole	C0003873	rheumatoid arthritis	2	[Q9H3N8, P07550]	DRUG	0.344096653
L02AB01	megestrol	C0019080	hemorrhage	1	[P11712]	DRUG	0.037128649
M01AE02	naproxen	C0024115	lung disorder	5	[P22309, P08246, P35354, P31645, P05177]	DRUG	0.035459478
N04BD01	selegiline	C0023470	myelogenous leukemia	1	[P08183]	DRUG	0.252941869
L04AX04	lenalidomide	C0699744	ear infection	4	[P01375, P19838, P35354, P23219]	DRUG	0.041952526
H02AB06	prednisolone	C0017601	glaucoma	1	[P04150]	DRUG_AND_METABOLITE	0.077866045
C01BD01	amiodarone	C0018801	heart failure	2	[Q14524, Q12809]	DRUG	0.023338897
C01BD01	amiodarone	C0018802	congestive heart failure	2	[Q14524, Q12809]	DRUG	0.023338897
J01DB04	cefazolin	C0002871	anemia	2	[P02768, P27169]	DRUG	0.005601404
N02CC06	eletriptan	C1527304	allergic reaction	1	[P41595]	DRUG	0.053194386
N02CC06	eletriptan	C0005967	bone neoplasm	2	[P11509, P08183]	DRUG	0.343067255
M01AE02	naproxen	C0024141	lupus	2	[P08246, P33527]	DRUG	0.27456334
D06BB10	imiquimod	C0041912	upper respiratory tract infection	1	[Q9NYK1]	DRUG	0.14501301
N04BC04	ropinirole	C0236048	Gastric Polyps	1	[Q13639]	DRUG	0.236442909
A07DA03	loperamide	C0015230	rash	1	[P31645]	METABOLITE	0.199588919
A10BG02	rosiglitazone	C0015230	rash	2	[P37231, Q07869]	DRUG	0.041119026
M01AH03	valdecoxib	C0013295	duodenal ulcer	2	[P35354, P33261]	DRUG_AND_METABOLITE	0.017396684
M01AC06	meloxicam	C0030920	peptic ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.002574643
L01XX11	estramustine	C0020538	hypertension	7	[P20815, P03372, O15244, Q02928, P11712, Q12791, Q92731]	DRUG_AND_METABOLITE	0.00225078
N05AH02	clozapine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.07578866
N05AH03	olanzapine	C0015695	liver fatty	1	[P02768]	DRUG	0.166969633
H02AB02	dexamethasone	C0011603	dermatitis	1	[P47712]	METABOLITE	0.336273178
N05AB04	prochlorperazine	C0009951	convulsions	2	[P08908, P31645]	DRUG_AND_METABOLITE	0.060419655
N05AH03	olanzapine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.008887027
C07AA06	timolol	C0009319	colitis	1	[P08183]	DRUG	0.126563037
N06AX16	venlafaxine	C0011603	dermatitis	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.114661067
D05BB02	acitretin	C0001418	adenocarcinoma	10	[P35354, P10826, P23219, P43088, P35408, P34995, P29762, P43116, P11511, P29373]	METABOLITE	0.010468668
N04BC04	ropinirole	C0030354	papilloma	1	[P05177]	DRUG	0.4999421
N03AF01	carbamazepine	C0009951	convulsions	7	[P35498, P08183, Q99250, P04156, Q9NY46, P08908, P35354]	METABOLITE	9.71969E-06
C10AB04	gemfibrozil	C0015230	rash	2	[P37231, Q07869]	DRUG	0.020237105
M01AE01	ibuprofen	C0018524	hallucinations	2	[P08183, P33527]	DRUG	0.084103037
A02BC02	pantoprazole	C0011849	diabetes mellitus	3	[P11712, P08684, P10632]	METABOLITE	0.054232974
N05AX08	risperidone	C0042514	ventricular tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.057756081
N02AE01	buprenorphine	C0033975	psychosis	1	[P31645]	DRUG	0.100870409
H02AB02	dexamethasone	C0085660	Aseptic necrosis	1	[P08183]	DRUG_AND_METABOLITE	0.075667737
R03DA04	theophylline	C0018681	headache	1	[P01375]	METABOLITE	0.094952502
C10AB04	gemfibrozil	C0022346	jaundice	1	[Q9Y6L6]	DRUG	0.014253709
N05AD01	haloperidol	C0014130	Endocrine Disorders	3	[O95259, Q12809, P04798]	DRUG	0.193456647
N04BC04	ropinirole	C0042109	urticaria	1	[P07550]	DRUG	0.0608928
L02BG04	letrozole	C0020538	hypertension	1	[P11511]	DRUG	0.092998912
G02CB03	cabergoline	C0085649	peripheral edema	1	[P08588]	DRUG	0.03222962
N07BB01	disulfiram	C0019158	hepatitis	1	[P05181]	DRUG	0.093864358
N04BC02	pergolide	C0027051	myocardial infarction	3	[P07550, P08588, P18089]	DRUG	0.078146652
B05BC01	mannitol	C0018681	headache	1	[P29475]	METABOLITE	0.118181872
N05AB04	prochlorperazine	C0009806	constipation	2	[P46098, P31645]	DRUG_AND_METABOLITE	0.001643274
J01DB01	cephalexin	C0019158	hepatitis	1	[P02768]	DRUG	0.060203322
S01EA05	brimonidine	C0011849	diabetes mellitus	1	[P18089]	DRUG_AND_METABOLITE	0.144785429
N03AF02	oxcarbazepine	C0009319	colitis	1	[Q14524]	DRUG	0.10492878
N07XX02	riluzole	C0684249	lung cancer	3	[Q9UNQ0, P04798, P05177]	DRUG	0.099646383
J01EC02	sulfadiazine	C0027720	nephrosis	1	[P02768]	METABOLITE	0.060643265
N05AX12	aripiprazole	C0042514	ventricular tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.056270313
J01AA08	minocycline	C0006266	bronchospasm	5	[P09917, P14780, P15692, P08253, P01584]	DRUG	0.003335247
J01BA01	chloramphenicol	C0023418	leukemia	1	[P20815]	DRUG_AND_METABOLITE	0.284120681
N05AH04	quetiapine	C0018524	hallucinations	2	[P08183, P36544]	DRUG	0.063596471
C09CA01	losartan	C0231218	malaise	1	[Q08499]	DRUG	0.019028106
N05AH02	clozapine	C0043144	wheezing	4	[P07550, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.193579561
M01AB15	ketorolac	C0009951	convulsions	1	[P35354]	DRUG	0.152175558
N05AE04	ziprasidone	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG	0.011833296
L01XE02	gefitinib	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.304694387
R03AC12	salmeterol	C0013595	eczema	1	[P07550]	DRUG	0.082841128
L04AX02	thalidomide	C0042487	venous thrombosis	1	[P00488]	METABOLITE	0.284207873
N04BD01	selegiline	C0015230	rash	3	[P28223, P08908, P31645]	METABOLITE	0.042305552
N02AX02	tramadol	C0015672	fatigue	1	[P31645]	DRUG_AND_METABOLITE	0.027162705
C07AB04	acebutolol	C0018524	hallucinations	1	[P08183]	DRUG	0.051022002
N05AG02	pimozide	C0014549	grand mal	2	[Q99250, P35498]	DRUG	0.034115357
N06AB03	fluoxetine	C0442874	neuropathy	1	[P08183]	DRUG	0.178569817
N05AH02	clozapine	C0878544	cardiomyopathy	2	[Q12809, P08588]	DRUG_AND_METABOLITE	0.128052648
C09CA01	losartan	C0013404	dyspnea	1	[P12821]	DRUG	0.054940301
J01MA01	ofloxacin	C0009951	convulsions	2	[P08183, P33527]	DRUG	0.040353299
N01BA02	procaine	C0042109	urticaria	1	[P12319]	DRUG	0.092356341
M01AB02	sulindac	C0009319	colitis	2	[P35354, P37231]	DRUG_AND_METABOLITE	0.05272585
H02AB02	dexamethasone	C0027813	neuritis	1	[P08183]	DRUG_AND_METABOLITE	0.096973815
R03AC02	salbutamol	C0042109	urticaria	1	[P07550]	DRUG	0.018096702
N06AA10	nortriptyline	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000374019
N06AX16	venlafaxine	C0039231	tachycardia	3	[Q14524, P07550, P08588]	DRUG	0.000381574
H02AB07	prednisone	C0029456	osteoporosis	6	[P03372, P11511, P08684, P10275, P04278, Q92731]	DRUG_AND_METABOLITE	4.25611E-06
N03AF02	oxcarbazepine	C0575081	abnormal gait	1	[P35498]	DRUG	0.020490582
N06AB06	sertraline	C0006325	bruxism	1	[P31645]	DRUG_AND_METABOLITE	0.018096702
L02BA02	toremifene	C0040046	thrombophlebitis	3	[P22352, P03372, Q92731]	DRUG_AND_METABOLITE	0.020153847
A03FA03	domperidone	C0013604	edema	1	[P08588]	DRUG	0.03222962
M01AB08	etodolac	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.020619485
D01AC01	clotrimazole	C0015230	rash	1	[P09601]	DRUG	0.252941869
N02AA01	morphine	C0037763	spasm	1	[P21918]	METABOLITE	0.052191974
N06AF03	phenelzine	C0015672	fatigue	1	[P31645]	DRUG	0.035047926
C10AB02	bezafibrate	C0002871	anemia	1	[P07148]	DRUG	0.07443691
N06AA06	trimipramine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.022328811
L02BA02	toremifene	C0015672	fatigue	1	[P35354]	METABOLITE	0.081756348
N05AC02	thioridazine	C0011991	diarrhea	2	[P46098, A5X5Y0]	METABOLITE	0.014891624
N05AD01	haloperidol	C0152128	drug withdrawal	1	[P14416]	DRUG_AND_METABOLITE	0.031285789
R03AC12	salmeterol	C0013604	edema	1	[P08588]	DRUG	0.015405718
N04BC04	ropinirole	C0042024	urinary incontinence	2	[P28223, P21917]	DRUG_AND_METABOLITE	0.003874925
M04AA01	allopurinol	C0035455	rhinitis	1	[P00533]	METABOLITE	0.180834633
N06AX11	mirtazapine	C0023890	cirrhosis	1	[P08684]	DRUG	0.239951985
N06AX16	venlafaxine	C0011849	diabetes mellitus	5	[P11712, O15245, P08684, P18089, P07550]	DRUG	0.105539171
C09AA06	quinapril	C0039231	tachycardia	1	[P12821]	DRUG_AND_METABOLITE	0.007907224
C09CA06	candesartan	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.032885129
C03DB01	amiloride	C0003123	anorexia	6	[P28223, P28335, P28221, P41143, P31645, P14416]	DRUG	1.62616E-06
H02AB02	dexamethasone	C0011849	diabetes mellitus	6	[P11712, P47712, P08684, P05093, P35354, P10632]	DRUG_AND_METABOLITE	0.005393105
N05AB06	trifluoperazine	C0012833	dizziness	1	[P29274]	DRUG	0.057987175
M01AC01	piroxicam	C0019080	hemorrhage	1	[P11712]	DRUG	0.037128649
C09CA01	losartan	C0001824	agranulocytosis	3	[P16662, P22309, P08183]	DRUG	0.000362009
C07AG01	labetalol	C0574002	Pedal Edema	1	[P08588]	DRUG	0.02023865
G03BA03	testosterone	C0001430	adenomas	9	[Q16678, P50225, P04798, P03372, P06401, Q92731, Q06520, P05093, P05108]	METABOLITE	0.002473457
N06DX01	memantine	C0009806	constipation	1	[P46098]	DRUG	0.028561234
M01AE02	naproxen	C0007097	carcinoma	15	[P35354, P33527, P23219, P49810, P09917, P63000, Q9H3N8, P42330, P10632, Q9Y5N1, P05177, P07858, P22309, P23975, P41222]	DRUG	0.360908965
R03DC01	zafirlukast	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.056872592
L04AX02	thalidomide	C0042345	varicose vein	2	[P01375, P00488]	METABOLITE	0.034299094
N06DA03	rivastigmine	C0020538	hypertension	1	[P31645]	DRUG	0.132975242
N06AA04	clomipramine	C0019158	hepatitis	2	[P05181, P02768]	METABOLITE	0.133185629
N05AG02	pimozide	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.067456992
N06AX11	mirtazapine	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.000261134
C01BA01	quinidine	C0019080	hemorrhage	1	[P11712]	DRUG	0.118450023
A10BB07	glipizide	C0013595	eczema	1	[P37231]	DRUG	0.089912296
A10BB09	gliclazide	C1458155	breast neoplasm	1	[P15692]	DRUG	0.394838288
N06AX21	duloxetine	C0037763	spasm	2	[P14867, P21918]	DRUG	0.019826646
R01AD01	beclomethasone	C0043144	wheezing	5	[P09917, P04150, P35354, P23219, P35228]	DRUG_AND_METABOLITE	0.014025764
N03AB02	phenytoin	C0085610	sinus bradycardia	1	[Q14524]	DRUG	0.027044096
N04BX02	entacapone	C0013395	Dyspepsia	1	[P21964]	DRUG_AND_METABOLITE	0.007907224
N06AX21	duloxetine	C0004093	asthenia	3	[P31645, P28223, P35354]	METABOLITE	0.001729681
N04BX02	entacapone	C0013384	dyskinesia	1	[P21964]	DRUG_AND_METABOLITE	0.023644115
C07AB04	acebutolol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.054232974
C07AB04	acebutolol	C0018801	heart failure	1	[P07550]	DRUG	0.054232974
J02AC03	voriconazole	C0740401	perforated duodenal ulcer	1	[P33261]	DRUG	0.033976159
N02AX02	tramadol	C0040136	thyroid neoplasia	1	[P23975]	DRUG_AND_METABOLITE	0.46578458
B05BC01	mannitol	C0009951	convulsions	3	[P08183, P07339, P29475]	METABOLITE	0.157888943
N05BA01	diazepam	C0009806	constipation	1	[P46098]	DRUG	0.051686979
N02CA01	dihydroergotamine	C0042109	urticaria	1	[P07550]	DRUG	0.099139302
J01AA07	tetracycline	C0020538	hypertension	2	[P08254, P08253]	DRUG_AND_METABOLITE	0.099373048
N06AB06	sertraline	C0006266	bronchospasm	2	[P11229, P20309]	DRUG_AND_METABOLITE	0.190102925
N06AA10	nortriptyline	C0013604	edema	1	[P08588]	DRUG	0.06589552
N02CC06	eletriptan	C0009806	constipation	1	[P41595]	DRUG	0.023338897
A02BC04	rabeprazole	C0017152	gastritis	3	[P20648, P23219, P35354]	DRUG	0.004776493
R03DC01	zafirlukast	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.052175416
N05AX12	aripiprazole	C0020517	hypersensitivity	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	0.000221093
L04AX02	thalidomide	C0027651	tumor	24	[P04798, P21802, P35354, P01375, P19838, P33765, P21980, Q08188, P05181, P05177, P06239, O15399, P20815, P23219, Q04609, P54687, P15104, P24298, P53985, Q08499, P47897, P33261, P21554, P35348]	METABOLITE	0.499995859
M01AC01	piroxicam	C0019158	hepatitis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.004222847
N05AX12	aripiprazole	C0020538	hypertension	11	[P20815, P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	8.9672E-05
N05AB03	perphenazine	C0009806	constipation	2	[P41595, P31645]	METABOLITE	0.002659644
C10AA03	pravastatin	C0231528	myalgia	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.094288684
N05AX12	aripiprazole	C0020550	hyperthyroidism	1	[P07550]	DRUG_AND_METABOLITE	0.165237296
A07EA06	budesonide	C0318712	gastroenteritis viral	2	[P23219, P35354]	METABOLITE	0.020490582
N06AB06	sertraline	C0018524	hallucinations	1	[P08183]	DRUG	0.133343956
N05CF02	zolpidem	C1458155	breast neoplasm	5	[P08684, P30536, O00591, P05177, P20815]	DRUG	0.4044417
L01AA01	cyclophosphamide	C0021311	infection	1	[P23219]	DRUG	0.338647638
M01AB02	sulindac	C0024141	lupus	1	[P04798]	DRUG	0.233518101
N05AH04	quetiapine	C0018799	heart disease	5	[Q12809, P31645, P08588, P07550, P41595]	DRUG_AND_METABOLITE	0.038338192
G04BE08	tadalafil	C0020538	hypertension	1	[Q08499]	DRUG	0.310280794
N05AH04	quetiapine	C0006325	bruxism	1	[P31645]	DRUG_AND_METABOLITE	0.026810317
N06AA11	protriptyline	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.010316539
A04AA02	granisetron	C0042024	urinary incontinence	1	[P28223]	DRUG	0.043328481
N02CC07	frovatriptan	C0003123	anorexia	1	[P28221]	DRUG	0.026275405
N03AF02	oxcarbazepine	C0038220	status epilepticus	1	[P35498]	DRUG	0.027706733
N06AX21	duloxetine	C0152032	urinary hesitancy	2	[P02768, P23219]	METABOLITE	0.168674498
C01BA01	quinidine	C0019158	hepatitis	1	[P05181]	DRUG	0.173871165
N04BC04	ropinirole	C0003123	anorexia	5	[P28223, P21917, P28335, P28221, P14416]	DRUG_AND_METABOLITE	4.24904E-06
N03AB02	phenytoin	C0085584	encephalopathy	4	[P14867, P18505, P18507, P08183]	DRUG	0.000772249
N04BC02	pergolide	C0001430	adenomas	1	[Q13639]	DRUG	0.284114407
A03FA02	cisapride	C1527304	allergic reaction	1	[P41595]	DRUG	0.102062496
R01AD01	beclomethasone	C0152459	striae	1	[P35354]	DRUG_AND_METABOLITE	0.133868815
G03BA03	testosterone	C0149931	migraine	2	[P03372, P08684]	METABOLITE	0.060656663
M01AE09	flurbiprofen	C0002871	anemia	3	[P10145, P02768, P07148]	DRUG	0.002547431
M01AE09	flurbiprofen	C0002878	hemolytic anemia	1	[P22309]	DRUG	0.076004516
A02BC02	pantoprazole	C0011570	mental depression	2	[P33261, P08684]	DRUG_AND_METABOLITE	0.015183287
C01BB02	mexiletine	C0428977	bradycardia	1	[Q14524]	DRUG	0.036361911
A02BC01	omeprazole	C0039591	testicle pain	1	[Q8NER1]	DRUG	0.025719012
J01EA01	trimethoprim	C0027947	neutropenia	1	[P08183]	DRUG	0.051619168
M01AE02	naproxen	C0015230	rash	3	[P28223, P08908, P31645]	DRUG	0.080087538
A03FA03	domperidone	C0004093	asthenia	1	[P28223]	DRUG	0.037086334
N06AA04	clomipramine	C0349231	phobia	1	[P31645]	DRUG_AND_METABOLITE	0.025524636
N05AX08	risperidone	C0001824	agranulocytosis	1	[P08183]	DRUG	0.115784639
N06AB03	fluoxetine	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG_AND_METABOLITE	2.45495E-05
N01BB01	bupivacaine	C0242184	hypoxia	5	[P22460, P16050, P10275, Q14524, Q12809]	METABOLITE	0.017010076
N06AX06	nefazodone	C0020615	hypoglycemia	1	[P07550]	METABOLITE	0.104607438
J02AC03	voriconazole	C0013395	Dyspepsia	1	[P23219]	DRUG	0.018943768
G04BE03	sildenafil	C0027051	myocardial infarction	4	[Q08499, P04798, P11712, P33261]	DRUG	0.0483478
N05AX12	aripiprazole	C0020615	hypoglycemia	1	[P07550]	DRUG_AND_METABOLITE	0.132975242
N05BA01	diazepam	C0015230	rash	1	[P08908]	DRUG	0.306667139
M01AB05	diclofenac	C0015230	rash	2	[P28223, P08908]	DRUG	0.17080113
R03AC02	salbutamol	C0021311	infection	1	[P07550]	DRUG	0.155436654
C08CA01	amlodipine	C0011849	diabetes mellitus	3	[P11712, P08684, P10632]	DRUG	0.04489205
M01AH02	rofecoxib	C0024299	lymphoma	1	[P35354]	DRUG_AND_METABOLITE	0.416586515
J05AF02	didanosine	C0231528	myalgia	1	[Q08499]	METABOLITE	0.107464244
N06AX16	venlafaxine	C0011991	diarrhea	1	[P46098]	DRUG	0.10492878
C07AG02	carvedilol	C0003864	arthritis	2	[P15692, P19320]	DRUG	0.033221489
J05AE03	ritonavir	C0027022	myeloproliferative disorders	1	[P08183]	DRUG	0.163392504
N02CC03	zolmitriptan	C0010709	cyst	1	[P05177]	DRUG	0.44396649
C09CA06	candesartan	C0022116	ischemia	1	[P50052]	DRUG_AND_METABOLITE	0.060419655
N05CF02	zolpidem	C0149931	migraine	1	[P08684]	DRUG	0.084103037
M01AB15	ketorolac	C0006266	bronchospasm	3	[P10145, P35354, P23219]	DRUG	0.027964493
N05AH03	olanzapine	C0015230	rash	5	[P07550, P21731, P28223, P08908, P31645]	DRUG	0.011832432
N06BA01	amphetamine	C0003123	anorexia	9	[P28223, P21917, P28335, P21397, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
N05AH03	olanzapine	C0004096	asthma	4	[P07550, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.112404615
N05AH03	olanzapine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.008887027
L01XE02	gefitinib	C0018799	heart disease	6	[Q13557, Q15831, Q9Y243, P28482, Q9NRM7, P27361]	DRUG_AND_METABOLITE	0.410087928
C09CA04	irbesartan	C0043144	wheezing	1	[P23219]	DRUG_AND_METABOLITE	0.190102925
J02AC01	fluconazole	C0001824	agranulocytosis	1	[P08183]	DRUG	0.037092814
C10AA05	atorvastatin	C0002994	angioedema	1	[P27487]	DRUG_AND_METABOLITE	0.007093731
G03XA01	danazol	C0013604	edema	1	[P08588]	METABOLITE	0.03222962
B01AC07	dipyridamole	C0027051	myocardial infarction	2	[Q08499, P00813]	DRUG	0.116737948
N02AA03	hydromorphone	C0042024	urinary incontinence	1	[P21917]	METABOLITE	0.05799926
M03BX08	cyclobenzaprine	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.138056035
G03BA03	testosterone	C0149871	deep vein thrombosis	2	[P03372, Q92731]	METABOLITE	0.082415968
C08CA02	felodipine	C0015230	rash	1	[Q16548]	METABOLITE	0.252941869
C02CA04	doxazosin	C0027051	myocardial infarction	2	[P33261, P18089]	DRUG_AND_METABOLITE	0.123597305
N05AB02	fluphenazine	C0003123	anorexia	4	[P28223, P21917, P28335, P14416]	DRUG_AND_METABOLITE	0.000282782
J05AE03	ritonavir	C0027051	myocardial infarction	3	[P11712, P33261, P05177]	DRUG	0.04284012
N02CA01	dihydroergotamine	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.15191224
C10AA02	lovastatin	C0003864	arthritis	1	[P07858]	METABOLITE	0.471837917
N07XX02	riluzole	C0029456	osteoporosis	1	[P04798]	DRUG	0.102050764
M01AE03	ketoprofen	C0017152	gastritis	3	[P10145, P23219, P35354]	DRUG	0.00047115
G04CA03	terazosin	C0018801	heart failure	1	[Q12809]	DRUG	0.168674498
A07DA03	loperamide	C0015672	fatigue	1	[P31645]	METABOLITE	0.039002635
L01BC06	capecitabine	C0010054	coronary artery disease	1	[P02768]	METABOLITE	0.268026518
N05AA01	chlorpromazine	C0031511	pheochromocytoma	24	[P05177, P11509, P32238, P08183, P04156, P05771, Q12809, Q09470, P35354, P30874, P32239, P20815, P05181, P04629, P23975, P10275, P17252, P29475, P09917, P36544, P26447, Q9Y5S8, P17405, P47989]	DRUG	0.303471269
M01AH01	celecoxib	C0149931	migraine	5	[P28223, P21917, P31645, P08684, P28335]	DRUG	9.09152E-05
N03AB02	phenytoin	C0085662	macrocytosis	1	[P02768]	DRUG	0.144630924
G03BA03	testosterone	C0007784	cerebral hemorrhage	1	[P03372]	METABOLITE	0.397977699
J05AF03	zalcitabine	C0149931	migraine	1	[P08684]	DRUG	0.095416353
N06AB04	citalopram	C0009951	convulsions	3	[P08183, P08908, P31645]	DRUG	0.017783546
G03AC06	medroxyprogesterone	C0000786	spontaneous abortion	2	[P06401, P10275]	METABOLITE	0.002473457
G03AC06	medroxyprogesterone	C0029456	osteoporosis	3	[P03372, P08684, P10275]	METABOLITE	0.000643413
M01AH03	valdecoxib	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000208809
N02AX02	tramadol	C0015230	rash	1	[P31645]	DRUG_AND_METABOLITE	0.134281172
C01BC03	propafenone	C0039231	tachycardia	1	[Q14524]	DRUG	0.021600815
C09AA04	perindopril	C0015927	fetal death	1	[P12821]	DRUG_AND_METABOLITE	0.068621885
C09CA02	eprosartan	C0023530	leukopenia	1	[Q92887]	DRUG	0.030408848
L01XE01	imatinib	C0009319	colitis	5	[Q04912, P08183, Q9Y616, P00918, P20783]	DRUG	0.368018486
A04AA01	ondansetron	C0026650	movement disorders	2	[P14416, P35462]	DRUG	0.03389451
N05AC02	thioridazine	C0085649	peripheral edema	1	[P08588]	DRUG	0.063186267
M04AA01	allopurinol	C0012833	dizziness	1	[P29274]	METABOLITE	0.041156839
N07BB04	naltrexone	C0024117	COPD	1	[P31645]	DRUG	0.138585458
G03AC06	medroxyprogesterone	C0000768	malformations	3	[P03372, P26439, P10275]	METABOLITE	0.000104917
M04AA01	allopurinol	C0004096	asthma	7	[P00533, P16220, P00813, P47989, P29274, Q08499, P12931]	METABOLITE	0.036564399
A02BC01	omeprazole	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.072104339
N06AX16	venlafaxine	C0442874	neuropathy	2	[Q9UQD0, P08183]	DRUG	0.086884165
N04BC05	pramipexole	C0020615	hypoglycemia	1	[P07550]	DRUG	0.103034195
A02BC04	rabeprazole	C0030305	pancreatitis	3	[Q99895, P04798, P35354]	DRUG	0.024401265
C01BB01	lidocaine	C0162297	respiratory arrest	1	[Q9UQD0]	DRUG	0.065976505
N06BA09	atomoxetine	C0041912	upper respiratory tract infection	2	[P07550, P17252]	DRUG	0.465090213
A16AA04	cysteamine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.10492878
N05AC02	thioridazine	C0011603	dermatitis	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.07632744
N05AB06	trifluoperazine	C0009951	convulsions	13	[O43526, P35498, Q9UBS5, P08183, P36544, Q99250, P04156, Q9NY46, P30874, P08908, P31645, P35354, P29475]	DRUG	2.08794E-05
G03DA04	progesterone	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.190093588
N05AD01	haloperidol	C0014549	grand mal	2	[Q99250, P35498]	DRUG	0.034115357
N06DX01	memantine	C0009319	colitis	1	[P46098]	DRUG	0.172860645
N07BB04	naltrexone	C0028768	obsessive compulsive disorder	1	[P31645]	DRUG	0.020619485
A10BB09	gliclazide	C0004096	asthma	1	[P15692]	DRUG	0.105539171
N05AC02	thioridazine	C0004096	asthma	4	[P07550, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.121673094
G03AC06	medroxyprogesterone	C0149741	nipple discharge	1	[P03372]	DRUG_AND_METABOLITE	0.021841092
C10AA02	lovastatin	C0024141	lupus	1	[P05362]	DRUG	0.499995859
G03AC06	medroxyprogesterone	C0520474	osteonecrosis	1	[P08183]	DRUG_AND_METABOLITE	0.031878908
C10AB02	bezafibrate	C0021311	infection	2	[P37231, Q07869]	DRUG	0.183580272
C09CA01	losartan	C0037011	shoulder pain	1	[Q08499]	DRUG	0.019028106
N06AX05	trazodone	C0020538	hypertension	11	[P20815, P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	0.00012305
N06AX06	nefazodone	C0020538	hypertension	12	[P20815, P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588, Q14289]	METABOLITE	6.40355E-07
L01AX03	temozolomide	C0021311	infection	1	[P00519]	DRUG	0.264908626
L01BA01	methotrexate	C0023530	leukopenia	3	[Q92887, Q9NPD5, P08183]	DRUG	0.001308799
N06AA09	amitriptyline	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.012488203
N02CC01	sumatriptan	C0038525	subarachnoid hemorrhage	2	[P07550, P08588]	DRUG	0.018096702
N06BA01	amphetamine	C0042109	urticaria	1	[P07550]	METABOLITE	0.139072108
C03DA04	eplerenone	C0015672	fatigue	1	[P04150]	DRUG	0.020490582
N03AX11	topiramate	C0085584	encephalopathy	1	[P14867]	DRUG	0.084819498
N02AA01	morphine	C0242184	hypoxia	1	[Q12809]	DRUG_AND_METABOLITE	0.376648154
N05BA01	diazepam	C0003123	anorexia	1	[P14416]	DRUG	0.127583335
C09AA09	fosinopril	C0003811	arrhythmia	1	[P12821]	DRUG	0.011557989
C09AA03	lisinopril	C0033860	psoriasis	1	[P12821]	DRUG	0.055755321
M01AC06	meloxicam	C0030305	pancreatitis	1	[P35354]	DRUG_AND_METABOLITE	0.0757759
L04AX02	thalidomide	C0041582	ulcer	1	[P01375]	DRUG	0.117247144
D05BB02	acitretin	C0017152	gastritis	2	[P23219, P35354]	METABOLITE	0.013399503
M01AE01	ibuprofen	C0018834	heartburn	1	[P23219]	DRUG	0.066764793
C08CA05	nifedipine	C0149931	migraine	4	[O00555, P28223, P35498, P08684]	DRUG	0.0005807
M01AE01	ibuprofen	C0018802	congestive heart failure	1	[Q9Y2I1]	DRUG	0.255299528
M01AE01	ibuprofen	C0018801	heart failure	1	[Q9Y2I1]	DRUG	0.255299528
C09CA03	valsartan	C0027947	neutropenia	1	[Q9NPD5]	DRUG	0.022511552
N04BD01	selegiline	C0699893	skin carcinoma	2	[P11509, P05181]	DRUG_AND_METABOLITE	0.43775151
M05BA06	ibandronate	C0020443	hypercholesterolemia	1	[P37268]	DRUG	0.021299045
N06AX21	duloxetine	C0041912	upper respiratory tract infection	7	[P07550, P04156, Q13936, P35354, P23219, P17252, P09917]	METABOLITE	0.31590567
L01AB01	busulfan	C0020538	hypertension	2	[P11086, P08263]	DRUG	0.044396476
C09CA01	losartan	C0149931	migraine	2	[P12821, P08684]	DRUG	0.013399503
M03BX08	cyclobenzaprine	C0011991	diarrhea	1	[P46098]	DRUG	0.116737948
L04AX02	thalidomide	C0042769	viral infection	1	[P21980]	METABOLITE	0.207982133
B05BC01	mannitol	C0024115	lung disorder	6	[P08183, P35247, P29460, P11226, P36222, P29475]	METABOLITE	0.064439777
N05AH03	olanzapine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.005067209
N06AX16	venlafaxine	C0006384	bundle branch block	1	[Q14524]	METABOLITE	0.020217132
G02CB03	cabergoline	C0013604	edema	1	[P08588]	DRUG	0.03222962
N04BC04	ropinirole	C0038525	subarachnoid hemorrhage	2	[P07550, P08588]	DRUG	0.008738741
N05AG02	pimozide	C0042109	urticaria	1	[P07550]	DRUG	0.12340561
M01AE12	oxaprozin	C0004096	asthma	2	[P35354, P23219]	DRUG	0.023202726
M01AE12	oxaprozin	C0004093	asthenia	1	[P35354]	DRUG	0.016169699
G03CA03	estradiol	C0030305	pancreatitis	2	[P05181, P04798]	DRUG_AND_METABOLITE	0.147941146
M01AH03	valdecoxib	C0009951	convulsions	4	[P33527, P08908, P31645, P35354]	DRUG_AND_METABOLITE	0.020490582
G03DA04	progesterone	C0019158	hepatitis	3	[P05181, P11509, P02768]	METABOLITE	0.037915264
G03BA03	testosterone	C0021311	infection	2	[P03372, P11413]	DRUG_AND_METABOLITE	0.4999421
N05AA01	chlorpromazine	C0242422	Parkinson	14	[P21917, P05181, Q01959, P32238, P08183, P21554, P27338, P35354, P50406, P08908, P31645, Q9UQD0, P14416, P35462]	DRUG_AND_METABOLITE	3.52831E-05
N03AX16	pregabalin	C0013384	dyskinesia	2	[O00555, Q9NY47]	DRUG	0.003300583
N06AX16	venlafaxine	C0006325	bruxism	1	[P31645]	DRUG_AND_METABOLITE	0.031285789
D01AC02	miconazole	C0030794	pelvic pain	1	[P11511]	DRUG	0.044396476
N05AH02	clozapine	C0037763	spasm	4	[P18507, P14867, P21918, P28472]	DRUG_AND_METABOLITE	7.81851E-05
N04BC05	pramipexole	C0012813	diverticulitis	1	[P31645]	DRUG	0.07443691
N02AA03	hydromorphone	C0152032	urinary hesitancy	1	[P23219]	DRUG	0.17352585
C09CA01	losartan	C0231528	myalgia	1	[Q08499]	DRUG	0.107464244
D07AC13	mometasone	C0017601	glaucoma	1	[P04150]	METABOLITE	0.020153847
D10AA02	methylprednisolone	C0029456	osteoporosis	2	[P08684, P10275]	DRUG_AND_METABOLITE	0.005849775
N05AB06	trifluoperazine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.002124178
N06AX05	trazodone	C0042514	ventricular tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.057756081
N06AX21	duloxetine	C0004134	ataxia	2	[P35498, Q14643]	DRUG	0.078146652
C09AA09	fosinopril	C0039231	tachycardia	1	[P12821]	DRUG	0.007907224
N03AF02	oxcarbazepine	C0041912	upper respiratory tract infection	1	[Q16548]	DRUG	0.248968302
N01BB09	ropivacaine	C0006145	breast disorders	1	[P00533]	METABOLITE	0.044306701
N06DA03	rivastigmine	C0027051	myocardial infarction	2	[P06276, P31645]	DRUG	0.034440795
N02CC01	sumatriptan	C0038454	cerebrovascular accident	3	[P03372, P28223, P07550]	DRUG	0.046170817
L01BA01	methotrexate	C0740394	hyperuricemia	2	[Q9NSA0, P42898]	DRUG	0.002812013
N06AA12	doxepin	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.178449857
J05AG03	efavirenz	C1456784	paranoia	1	[P05177]	DRUG	0.012425662
C08CA05	nifedipine	C0009421	coma	1	[O00555]	DRUG	0.014940513
C09CA02	eprosartan	C0027947	neutropenia	1	[Q92887]	DRUG	0.025394378
C01DA02	nitroglycerin	C0015230	rash	1	[P09211]	METABOLITE	0.165987561
N04BD01	selegiline	C0600139	prostate cancer	11	[P08183, P05181, P10632, P08684, P05177, O75751, P33261, P20813, P07477, P35348, O60341]	METABOLITE	0.175999026
D01AC08	ketoconazole	C0018418	gynecomastia	1	[P11511]	DRUG	0.019693364
N06AA02	imipramine	C0018802	congestive heart failure	4	[Q9Y2I1, Q12809, P07550, O43306]	METABOLITE	0.025512592
C09AA13	moexipril	C0022658	nephropathy	1	[Q9BYF1]	DRUG	0.047374915
N06DA02	donepezil	C0029456	osteoporosis	1	[P08684]	DRUG	0.085700004
N04BC04	ropinirole	C0149931	migraine	4	[P28223, P21917, P08684, P28335]	DRUG	9.13424E-05
S01AA14	penicillin G	C0035078	renal failure	1	[P08183]	METABOLITE	0.173402837
N06AX05	trazodone	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.062610213
S01AA14	penicillin G	C0023530	leukopenia	1	[P08183]	METABOLITE	0.121869368
R03AC13	formoterol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.05003687
N06AA11	protriptyline	C0011991	diarrhea	1	[P46098]	DRUG	0.094719012
N04BC02	pergolide	C0015230	rash	3	[P07550, P28223, P08908]	DRUG_AND_METABOLITE	0.021040008
C08DB01	diltiazem	C0021311	infection	1	[Q13936]	DRUG	0.455476467
S01ED02	betaxolol	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	METABOLITE	5.45046E-05
N01BB01	bupivacaine	C0428977	bradycardia	1	[Q14524]	METABOLITE	0.023644115
J01AA08	minocycline	C0549473	thyroid cancer	4	[O14746, P14780, P08253, P15692]	DRUG	0.007649001
N06AX21	duloxetine	C0013384	dyskinesia	6	[Q14643, P35498, Q12791, P14416, P21917, P35462]	DRUG	0.000178986
N06BA01	amphetamine	C0015230	rash	5	[P14780, P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.037292444
R03DC03	montelukast	C1458140	bleeding diathesis	1	[P11712]	DRUG_AND_METABOLITE	0.041415522
N02CC01	sumatriptan	C0878544	cardiomyopathy	1	[P08588]	DRUG	0.212730719
L02BB03	bicalutamide	C0024115	lung disorder	1	[P04150]	DRUG	0.092356341
N06AA09	amitriptyline	C0004134	ataxia	2	[Q09470, P35498]	DRUG_AND_METABOLITE	0.086536365
A10BX02	repaglinide	C0022116	ischemia	1	[P37231]	DRUG	0.051665686
N06AX21	duloxetine	C0013395	Dyspepsia	1	[P23219]	METABOLITE	0.080593613
M03BX08	cyclobenzaprine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000794668
S01EE04	travoprost	C0019080	hemorrhage	1	[P21731]	METABOLITE	0.039903358
N06AA02	imipramine	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.187583024
N04BC02	pergolide	C0027651	tumor	5	[P08684, Q99720, Q13639, P35348, P07550]	DRUG	0.499995859
M01AB02	sulindac	C0020538	hypertension	2	[P37231, Q07869]	METABOLITE	0.105016252
G03HA01	cyproterone	C0018418	gynecomastia	1	[P11511]	DRUG	0.003094049
N02BA11	diflunisal	C0004093	asthenia	1	[P35354]	DRUG	0.028343005
H02AA02	fludrocortisone	C0021311	infection	1	[P04150]	DRUG_AND_METABOLITE	0.311927901
A02BC01	omeprazole	C0027651	tumor	13	[Q9UNQ0, P04798, Q16678, P08684, P08183, O15438, P18031, P05108, P05177, Q07820, P10632, P32247, P33261]	DRUG_AND_METABOLITE	0.205458767
P01AX06	atovaquone	C0009806	constipation	2	[P46098, P31645]	METABOLITE	0.018005107
R06AX02	cyproheptadine	C0015230	rash	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG	0.00390144
A07EC04	balsalazide	C0085605	hepatic failure	1	[O15111]	METABOLITE	0.027578662
R03BA08	ciclesonide	C0043144	wheezing	1	[P04150]	DRUG	0.105539171
N02CC01	sumatriptan	C0027932	neurosis	2	[P28223, P14416]	DRUG	0.004222847
J05AE01	saquinavir	C0011849	diabetes mellitus	5	[P11712, O15245, P08684, P02768, P10632]	DRUG	0.002455123
J01MA01	ofloxacin	C0009319	colitis	2	[P08183, Q9H015]	DRUG	0.047071362
C07AG02	carvedilol	C0011603	dermatitis	4	[P07550, P08908, P15692, P31645]	DRUG_AND_METABOLITE	0.00772744
C09CA02	eprosartan	C0039231	tachycardia	1	[P30556]	DRUG	0.012792437
M01AH02	rofecoxib	C0004096	asthma	6	[P09917, P35354, P23219, Q15722, P16050, P33527]	DRUG_AND_METABOLITE	0.014940513
N05BA01	diazepam	C0011991	diarrhea	1	[P46098]	DRUG	0.074254786
M01AH02	rofecoxib	C0004093	asthenia	3	[P31645, P28223, P35354]	DRUG_AND_METABOLITE	0.000305005
J05AE01	saquinavir	C0151826	chest pain substernal	1	[P02768]	DRUG	0.017292056
C08DB01	diltiazem	C0575081	abnormal gait	1	[P35498]	DRUG	0.043339606
N05BA12	alprazolam	C0020517	hypersensitivity	1	[P35367]	DRUG	0.103034195
G03CA03	estradiol	C0022346	jaundice	3	[Q9Y6L6, P22309, Q9NPD5]	DRUG	0.000156554
M01AE09	flurbiprofen	C0027051	myocardial infarction	6	[P35354, P10145, P02768, P08246, P11712, P23219]	DRUG_AND_METABOLITE	0.002681168
N05AE04	ziprasidone	C0018799	heart disease	5	[Q12809, P31645, P08588, P07550, P41595]	DRUG	0.039584291
L04AX04	lenalidomide	C0030794	pelvic pain	1	[Q08499]	DRUG	0.024401265
N06AA04	clomipramine	C0015230	rash	5	[P07550, P28223, P08908, P31645, P09211]	DRUG	0.057511501
M01AE01	ibuprofen	C0001824	agranulocytosis	4	[P16662, O60656, P22309, P08183]	DRUG	0.000555149
N06AB03	fluoxetine	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.058041029
N05AB02	fluphenazine	C0007787	transient ischemic attack	1	[P62158]	DRUG	0.110876596
N06AB04	citalopram	C0009806	constipation	2	[P46098, P31645]	DRUG	0.001735786
C03DB01	amiloride	C0019151	hepatic encephalopathy	2	[P14867, P35372]	DRUG	0.002400178
M01AB02	sulindac	C0020456	hyperglycemia	2	[P37231, P35354]	DRUG_AND_METABOLITE	0.013789483
N06AA10	nortriptyline	C0042109	urticaria	1	[P07550]	DRUG	0.110876596
G03AC06	medroxyprogesterone	C0149931	migraine	2	[P03372, P08684]	DRUG_AND_METABOLITE	0.003300583
C10AA04	fluvastatin	C0151798	hepatic necrosis	2	[P37231, P08684]	DRUG_AND_METABOLITE	0.020932885
L04AA13	leflunomide	C0018944	hematoma	1	[P11712]	DRUG	0.046668295
M01AX01	nabumetone	C0020456	hyperglycemia	1	[P35354]	DRUG_AND_METABOLITE	0.043470156
N06AB04	citalopram	C0006266	bronchospasm	1	[P11229]	DRUG	0.321076283
N04BC05	pramipexole	C0678222	breast cancer	4	[Q99720, Q01959, Q9H3N8, Q9Y5N1]	DRUG	0.499995859
L01XE01	imatinib	C0149931	migraine	2	[P08684, P06213]	DRUG	0.242837331
M01AB15	ketorolac	C0021311	infection	3	[P10145, P35354, P23219]	DRUG	0.09498999
G03AC06	medroxyprogesterone	C0149871	deep vein thrombosis	1	[P03372]	DRUG_AND_METABOLITE	0.054879508
J02AC02	itraconazole	C0018799	heart disease	1	[P20813]	DRUG_AND_METABOLITE	0.154732917
N06AA06	trimipramine	C0027051	myocardial infarction	14	[P02768, P21554, P13945, P05362, P06276, P07550, P11712, P33261, P31645, P23219, P05177, P08588, P18089, Q12791]	METABOLITE	0.002889839
M01AE01	ibuprofen	C0006266	bronchospasm	6	[P09917, P10145, P35354, P23219, O94956, P33527]	DRUG	0.05696568
C07AB03	atenolol	C0004096	asthma	1	[P07550]	DRUG	0.190102925
D05BB02	acitretin	C0684249	lung cancer	10	[P02768, P35354, P10826, P11511, P23219, P35408, P43116, P34995, P19793, P28702]	DRUG_AND_METABOLITE	0.000197937
N05AH04	quetiapine	C0878544	cardiomyopathy	2	[Q12809, P08588]	DRUG	0.094244523
N03AF01	carbamazepine	C0009806	constipation	2	[Q14524, P46098]	DRUG	0.002043067
M01AE03	ketoprofen	C0006266	bronchospasm	3	[P10145, P35354, P23219]	DRUG	0.027964493
N02CA01	dihydroergotamine	C0151744	myocardial ischemia	2	[P07550, P08588]	DRUG	0.042994642
A03FA01	metoclopramide	C0011570	mental depression	6	[P28223, P28335, P28222, P50406, P08908, P18825]	DRUG	2.90857E-07
M01AE01	ibuprofen	C0013395	Dyspepsia	1	[P23219]	DRUG	0.066764793
J01AA02	doxycycline	C0015230	rash	2	[P08254, P08253]	DRUG	0.046586487
N06AB04	citalopram	C0006325	bruxism	1	[P31645]	DRUG	0.015407438
A02BA01	cimetidine	C0033975	psychosis	1	[P28223]	DRUG	0.150666153
G02CB01	bromocriptine	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.007907224
C01EB03	indomethacin	C0008031	chest pain	1	[P02768]	DRUG	0.030205472
C01BC03	propafenone	C0042510	ventricular fibrillation	1	[Q14524]	DRUG	0.00976001
L04AA13	leflunomide	C0020538	hypertension	2	[P11712, Q14289]	DRUG	0.060428908
L02BA01	tamoxifen	C0032584	polyps	15	[P05177, P11509, P08183, P05771, P03372, P35354, Q92731, Q9UNQ0, P11511, P20815, P05181, Q16678, P04798, P10275, P17252]	METABOLITE	0.002642872
M01AC06	meloxicam	C0038013	ankylosing spondylitis	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.060597648
S01EC01	acetazolamide	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.131204502
N02CA01	dihydroergotamine	C0013604	edema	1	[P08588]	DRUG	0.059154548
N06AX16	venlafaxine	C0014549	grand mal	2	[Q99250, P35498]	METABOLITE	0.034115357
L01BA01	methotrexate	C0023890	cirrhosis	2	[P42898, O15439]	DRUG	0.07647345
N05CF01	zopiclone	C0013395	Dyspepsia	1	[P23219]	DRUG	0.028748417
J05AE01	saquinavir	C0011991	diarrhea	1	[Q92887]	DRUG	0.044087091
L04AX04	lenalidomide	C0022660	acute renal failure	1	[P01375]	DRUG	0.043339606
A16AA04	cysteamine	C0009806	constipation	2	[P46098, P31645]	DRUG_AND_METABOLITE	0.009421805
N07XX02	riluzole	C0242184	hypoxia	2	[Q9H2S1, Q14524]	DRUG	0.080482871
C01BA01	quinidine	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.023732516
D08AC02	chlorhexidine	C0037023	sialadenitis	2	[P14780, P08253]	DRUG	6.31065E-05
N05BC01	meprobamate	C0011603	dermatitis	8	[P07550, P01024, P26358, P28223, P08908, P31645, P50135, P09211]	METABOLITE	0.040813777
N05AX08	risperidone	C0028754	obesity	1	[P07550]	DRUG_AND_METABOLITE	0.210728759
A03FA01	metoclopramide	C0011991	diarrhea	1	[P46098]	DRUG	0.053194386
N04BC04	ropinirole	C0600139	prostate cancer	4	[P08684, P05177, P35348, P07550]	DRUG	0.451554712
M01AE01	ibuprofen	C0013295	duodenal ulcer	3	[P35354, P10145, P33261]	DRUG	0.004206122
N06AX21	duloxetine	C0013595	eczema	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.080593613
L01BA01	methotrexate	C0015927	fetal death	2	[P42898, P04818]	DRUG_AND_METABOLITE	0.106277208
N07XX02	riluzole	C0000768	malformations	1	[P04798]	DRUG	0.061427537
D06AA01	demeclocycline	C0019158	hepatitis	1	[P02768]	DRUG	0.093864358
M01AB05	diclofenac	C0032285	pneumonia	2	[P10145, P35354]	DRUG_AND_METABOLITE	0.065051826
A04AD12	aprepitant	C0013295	duodenal ulcer	1	[P33261]	DRUG_AND_METABOLITE	0.026393713
N04BC04	ropinirole	C0678222	breast cancer	2	[P08684, P05177]	DRUG	0.499995859
C08CA05	nifedipine	C0009806	constipation	1	[P46098]	DRUG	0.053677028
M01AB05	diclofenac	C0149931	migraine	4	[P28223, P21917, P08684, P28335]	DRUG	0.000955687
R03BA08	ciclesonide	C0017601	glaucoma	1	[P04150]	DRUG	0.027818585
A02BC03	lansoprazole	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.062641595
N06AB03	fluoxetine	C0038454	cerebrovascular accident	2	[Q08499, P28223]	DRUG_AND_METABOLITE	0.129024592
C10AA07	rosuvastatin	C0004096	asthma	1	[P33527]	DRUG	0.156888602
G03CA03	estradiol	C0006266	bronchospasm	2	[O94956, P33527]	DRUG	0.407134574
L02BA01	tamoxifen	C0004093	asthenia	1	[P35354]	DRUG	0.052406311
A02BC01	omeprazole	C0010054	coronary artery disease	2	[P08684, P04798]	DRUG_AND_METABOLITE	0.116737948
C09AA04	perindopril	C0007859	neck pain	1	[P12821]	DRUG_AND_METABOLITE	0.006405429
M03CA01	dantrolene	C0231528	myalgia	1	[P21817]	DRUG	0.038508848
G02CB03	cabergoline	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG	0.001077984
N06AB04	citalopram	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG	0.017783546
M01AE03	ketoprofen	C0035078	renal failure	1	[P41222]	DRUG	0.083870425
L04AX04	lenalidomide	C0022104	irritable bowel syndrome	1	[P01375]	DRUG	0.053194386
C10AA04	fluvastatin	C0023890	cirrhosis	2	[P08684, P37231]	METABOLITE	0.029491269
A08AA10	sibutramine	C0020517	hypersensitivity	2	[P41595, Q01959]	DRUG_AND_METABOLITE	0.012957975
L04AX04	lenalidomide	C0022116	ischemia	2	[P35354, P05181]	DRUG	0.018483876
L04AX02	thalidomide	C0041912	upper respiratory tract infection	4	[P01375, P19838, P35354, P23219]	DRUG_AND_METABOLITE	0.485588031
N06AA01	desipramine	C0013604	edema	1	[P08588]	DRUG	0.06870342
A10BB07	glipizide	C0020538	hypertension	2	[P37231, P11712]	DRUG	0.034299094
L02BA01	tamoxifen	C0024236	lymphedema	2	[P11509, P08684]	DRUG_AND_METABOLITE	0.002503382
J01MA01	ofloxacin	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.006545503
C08DB01	diltiazem	C0018790	cardiac arrest	2	[Q12809, Q13936]	DRUG	0.007907224
N05AB06	trifluoperazine	C0037763	spasm	2	[P14867, P21918]	DRUG_AND_METABOLITE	0.029913007
C08DB01	diltiazem	C0018799	heart disease	2	[Q12809, P11712]	DRUG	0.120976482
C01BC03	propafenone	C0035078	renal failure	1	[P08183]	DRUG_AND_METABOLITE	0.07118586
J04AC01	isoniazid	C0009951	convulsions	1	[P14780]	METABOLITE	0.163392504
C01BB02	mexiletine	C0004134	ataxia	1	[P35498]	DRUG	0.17352585
C01BA01	quinidine	C0035078	renal failure	1	[P08183]	DRUG	0.164896017
N06AB06	sertraline	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.027144316
N06BA01	amphetamine	C0038454	cerebrovascular accident	2	[P28223, P07550]	METABOLITE	0.262283953
A10BB07	glipizide	C0020615	hypoglycemia	1	[Q09428]	DRUG	0.035667691
N05AB02	fluphenazine	C0019158	hepatitis	1	[P05181]	DRUG	0.155269528
N05AH02	clozapine	C0021311	infection	1	[P07550]	DRUG_AND_METABOLITE	0.499995859
G03XA01	danazol	C0149741	nipple discharge	1	[P03372]	DRUG_AND_METABOLITE	0.037086334
C08DB01	diltiazem	C0018801	heart failure	1	[Q12809]	DRUG	0.126165567
C08DB01	diltiazem	C0018802	congestive heart failure	1	[Q12809]	DRUG	0.126165567
C09AA04	perindopril	C0015672	fatigue	1	[P12821]	DRUG_AND_METABOLITE	0.012425662
S01ED02	betaxolol	C0003123	anorexia	1	[P28335]	DRUG	0.063596471
J01FA01	erythromycin	C0018524	hallucinations	2	[P08183, P33527]	DRUG	0.012425662
C02CA04	doxazosin	C0023530	leukopenia	1	[P08183]	DRUG	0.06555312
N06AB04	citalopram	C0013604	edema	1	[P08588]	DRUG	0.036486436
H02AB07	prednisone	C0020538	hypertension	7	[P19099, P20815, P03372, P08235, P11511, Q92731, P04150]	DRUG_AND_METABOLITE	0.000153416
N02CC01	sumatriptan	C0022116	ischemia	1	[P05181]	METABOLITE	0.187583024
L04AA06	mycophenolic acid	C0018799	heart disease	1	[P37231]	DRUG_AND_METABOLITE	0.092452629
A10BB09	gliclazide	C0008031	chest pain	1	[P02768]	DRUG	0.006114053
N02CC04	rizatriptan	C0020517	hypersensitivity	1	[P41595]	METABOLITE	0.06457386
N06AB03	fluoxetine	C0026848	myopathy	1	[P10275]	METABOLITE	0.235566991
L04AX04	lenalidomide	C0242184	hypoxia	3	[P19838, P35354, P01375]	DRUG	0.035695087
N02CC04	rizatriptan	C0020538	hypertension	1	[P28223]	DRUG_AND_METABOLITE	0.212234884
N04BD01	selegiline	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.107484566
G03CA03	estradiol	C0006145	breast disorders	1	[P03372]	DRUG_AND_METABOLITE	0.085892844
J05AF01	zidovudine	C0231528	myalgia	1	[O00142]	METABOLITE	0.096910793
C10AA01	simvastatin	C0026848	myopathy	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.096195732
L01XE01	imatinib	C0040034	thrombocytopenia	1	[O60674]	DRUG	0.344712038
C09AA07	benazepril	C0021311	infection	2	[P42898, P12821]	DRUG_AND_METABOLITE	0.034852775
A10BG03	pioglitazone	C0018802	congestive heart failure	1	[P37231]	DRUG_AND_METABOLITE	0.103034195
A10BG03	pioglitazone	C0018801	heart failure	1	[P37231]	DRUG_AND_METABOLITE	0.103034195
A10BG03	pioglitazone	C0041912	upper respiratory tract infection	3	[P23219, P37231, Q07869]	DRUG	0.111539926
N06AA04	clomipramine	C0007784	cerebral hemorrhage	2	[P28223, P07550]	DRUG_AND_METABOLITE	0.30792048
L04AX04	lenalidomide	C0035078	renal failure	1	[P01375]	DRUG	0.089658424
N06AA04	clomipramine	C0011603	dermatitis	5	[P07550, P28223, P08908, P31645, P09211]	DRUG	0.131195597
L01XE01	imatinib	C0024299	lymphoma	20	[P06748, P31749, P10721, P53350, P22607, Q9UM73, P08183, P16234, P43403, P43405, O14965, P07948, P08581, Q13882, P04629, P60953, P35968, P33981, P28482, P27361]	DRUG	0.006192754
M01AH01	celecoxib	C0030305	pancreatitis	2	[P00918, P35354]	DRUG_AND_METABOLITE	0.100012956
N06AX21	duloxetine	C0013604	edema	1	[P08588]	DRUG	0.087386772
A10BG03	pioglitazone	C0018799	heart disease	5	[P37231, Q07869, P23219, P11712, P19793]	DRUG	0.001143468
D11AX10	finasteride	C0678222	breast cancer	5	[P08684, P14060, P10275, P20815, P18405]	DRUG_AND_METABOLITE	0.091398955
J01MA02	ciprofloxacin	C0025637	methemoglobinemia	1	[P05177]	DRUG	0.016169699
A02BC03	lansoprazole	C0013390	dysmenorrhea	1	[P04798]	DRUG	0.019028106
G02CB01	bromocriptine	C0011991	diarrhea	1	[P46098]	DRUG	0.084411206
C01EB03	indomethacin	C0001824	agranulocytosis	4	[Q92887, O60656, P22309, P08183]	DRUG	0.00014672
L01XE01	imatinib	C0032227	pleural effusion	1	[Q16790]	DRUG	0.255273053
C01BB02	mexiletine	C0030305	pancreatitis	1	[P05181]	DRUG	0.294827017
N06BA04	methylphenidate	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.00371205
N06AB06	sertraline	C0013604	edema	1	[P08588]	DRUG	0.042436544
N05AX12	aripiprazole	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.060823811
C01BD01	amiodarone	C0033860	psoriasis	1	[P04798]	DRUG	0.187962918
C08CA02	felodipine	C0039070	syncope	1	[P29274]	DRUG_AND_METABOLITE	0.042436544
A02BC01	omeprazole	C0010200	cough	1	[Q8NER1]	DRUG	0.021299045
L02BA01	tamoxifen	C0024141	lupus	2	[P04798, P03372]	DRUG_AND_METABOLITE	0.168049128
N06AB05	paroxetine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	7.87958E-05
N05BE01	buspirone	C0020538	hypertension	12	[P20815, P35348, P13945, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	6.31065E-05
A07EC01	sulfasalazine	C0001824	agranulocytosis	1	[Q92887]	DRUG	0.070518569
A02BC04	rabeprazole	C0442874	neuropathy	1	[P08183]	METABOLITE	0.169250637
C07AB02	metoprolol	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.000537217
A02BC02	pantoprazole	C0009319	colitis	1	[P08183]	DRUG_AND_METABOLITE	0.218238202
C10AA06	cerivastatin	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.030408848
N06BA04	methylphenidate	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.032253647
H02AB02	dexamethasone	C0018801	heart failure	1	[P08235]	DRUG_AND_METABOLITE	0.153623294
H02AB02	dexamethasone	C0018802	congestive heart failure	1	[P08235]	DRUG_AND_METABOLITE	0.153623294
C09AA08	cilazapril	C0007820	cerebrovascular disorder	1	[P12821]	DRUG	0.06495498
A02BC02	pantoprazole	C0009324	ulcerative colitis	1	[P08183]	DRUG_AND_METABOLITE	0.208479674
L04AA06	mycophenolic acid	C0018802	congestive heart failure	1	[P37231]	DRUG_AND_METABOLITE	0.040601904
L04AA06	mycophenolic acid	C0018801	heart failure	1	[P37231]	DRUG_AND_METABOLITE	0.040601904
N06AB05	paroxetine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.079473486
N06AA04	clomipramine	C0030920	peptic ulcer	1	[P33261]	DRUG_AND_METABOLITE	0.233163081
G04CA03	terazosin	C1527304	allergic reaction	3	[P41595, P35367, Q9H3N8]	METABOLITE	0.003004332
C07AG02	carvedilol	C0023530	leukopenia	1	[P08183]	DRUG	0.072104339
A07EC04	balsalazide	C0015672	fatigue	1	[P35354]	DRUG_AND_METABOLITE	0.025953097
C10AB05	fenofibrate	C0009319	colitis	2	[P12104, P37231]	DRUG_AND_METABOLITE	0.027382239
N06BA01	amphetamine	C0038325	Stevens - Johnson syndrome	1	[P14780]	METABOLITE	0.0608928
N03AB04	mephenytoin	C0019158	hepatitis	2	[P05181, P02768]	DRUG	0.042804682
N06AA02	imipramine	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.051022002
C09AA09	fosinopril	C0027051	myocardial infarction	1	[P12821]	DRUG	0.085527439
N04BC04	ropinirole	C0010709	cyst	1	[P05177]	DRUG	0.4999421
N06AA02	imipramine	C0018681	headache	2	[P05362, P29475]	METABOLITE	0.031044109
N06AA04	clomipramine	C0011206	delirium	2	[P32238, P21554]	METABOLITE	0.020093213
N06AX16	venlafaxine	C0428977	bradycardia	1	[Q14524]	METABOLITE	0.040021541
J01XE01	nitrofurantoin	C0030305	pancreatitis	1	[P05181]	DRUG	0.038001816
A07EA06	budesonide	C0027424	nasal congestion	1	[P35228]	METABOLITE	0.098229155
M01AH01	celecoxib	C0042109	urticaria	1	[P09917]	DRUG	0.099139302
L02BA01	tamoxifen	C0032285	pneumonia	1	[P35354]	DRUG	0.156118331
N06AA02	imipramine	C0020565	breast enlargement	1	[P05362]	METABOLITE	0.29910529
A10BG03	pioglitazone	C0027051	myocardial infarction	6	[P37231, Q07869, P11712, P33261, P23219, P05177]	DRUG	0.000777939
H02AB06	prednisolone	C0020538	hypertension	7	[P19099, P20815, P03372, P08235, P11511, Q92731, P04150]	DRUG_AND_METABOLITE	0.000153416
M01AH01	celecoxib	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.000832892
N01BA02	procaine	C0009951	convulsions	4	[P35498, P08183, Q99250, Q9NY46]	DRUG	0.019239124
N06AX11	mirtazapine	C0038363	ulcerative stomatitis	1	[P31645]	DRUG	0.028123725
L04AX01	azathioprine	C1261473	sarcoma	1	[Q16539]	METABOLITE	0.33319218
N02AA03	hydromorphone	C1510472	drug dependence	1	[P21964]	DRUG_AND_METABOLITE	0.028123725
N01BB09	ropivacaine	C0006266	bronchospasm	1	[P00533]	METABOLITE	0.33860389
N06AA09	amitriptyline	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.132264609
N04BC05	pramipexole	C0020473	hyperlipidemia	1	[P07550]	DRUG	0.168046548
J05AE01	saquinavir	C0009951	convulsions	2	[P08183, P33527]	DRUG	0.047831182
G04CA02	tamsulosin	C1527304	allergic reaction	2	[P19801, P35367]	DRUG	0.010731647
N05AH02	clozapine	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG_AND_METABOLITE	0.000229377
N06AB04	citalopram	C0013384	dyskinesia	2	[P14416, P35462]	DRUG	0.017115097
N07XX02	riluzole	C0242379	lung neoplasm malignant	3	[Q9UNQ0, P04798, P05177]	DRUG	0.092356341
N04BC05	pramipexole	C0040136	thyroid neoplasia	1	[P23975]	DRUG	0.499995859
M01AC06	meloxicam	C0038358	gastric ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.001156573
N06AA02	imipramine	C0020538	hypertension	16	[P20815, P35348, P13945, P07550, P21728, O15244, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089, P08588, Q12791, P29475]	METABOLITE	0.000116341
N05AH04	quetiapine	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG	6.90845E-05
S01AA14	penicillin G	C1527304	allergic reaction	1	[Q01959]	DRUG	0.127583335
H02AB02	dexamethasone	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.145537474
N06AB03	fluoxetine	C0026650	movement disorders	3	[P14416, P21917, P35462]	DRUG	0.002864229
N06AX16	venlafaxine	C0231528	myalgia	2	[P17252, P29475]	DRUG	0.085261294
J05AG03	efavirenz	C0019693	HIV infection	2	[P20813, P08684]	DRUG	0.017560596
N05BC01	meprobamate	C0011991	diarrhea	1	[P46098]	METABOLITE	0.152628093
N06AB06	sertraline	C0085649	peripheral edema	1	[P08588]	DRUG	0.042436544
A02BA04	nizatidine	C0009806	constipation	1	[P46098]	DRUG	0.027706733
N06AX16	venlafaxine	C0019080	hemorrhage	1	[P11712]	DRUG	0.170581113
J05AE03	ritonavir	C0027947	neutropenia	2	[Q92887, P08183]	DRUG	0.004601015
N06AB06	sertraline	C0013384	dyskinesia	1	[P14416]	DRUG_AND_METABOLITE	0.112841395
M03BX08	cyclobenzaprine	C0231528	myalgia	2	[Q8NER1, P05362]	METABOLITE	0.101814922
L01BC06	capecitabine	C0041912	upper respiratory tract infection	1	[P11387]	METABOLITE	0.434949141
L01CB01	etoposide	C0027947	neutropenia	2	[Q92887, P08183]	DRUG_AND_METABOLITE	0.004962197
N02CA01	dihydroergotamine	C0020538	hypertension	10	[P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG	0.000256201
N06AA02	imipramine	C0018524	hallucinations	6	[P08183, P36544, P35498, Q99250, P04156, Q9NY46]	DRUG_AND_METABOLITE	0.001281171
J05AF02	didanosine	C0030193	pain	1	[Q08499]	METABOLITE	0.03201379
D04AA32	diphenhydramine	C0043144	wheezing	4	[P50135, P23219, P11229, P20309]	DRUG	0.019239124
N04BC02	pergolide	C0027932	neurosis	2	[P28223, P14416]	DRUG_AND_METABOLITE	0.00183769
G04BD04	oxybutynin	C0020538	hypertension	1	[P20815]	DRUG	0.158026147
C10AA05	atorvastatin	C0021311	infection	1	[P27487]	DRUG_AND_METABOLITE	0.382492229
N01BB09	ropivacaine	C0036572	seizures	2	[Q99250, P35498]	METABOLITE	0.008304098
N02CA01	dihydroergotamine	C0013146	abuse	1	[P41595]	DRUG	0.038869302
N06AB03	fluoxetine	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.035667691
N06AA04	clomipramine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.020093213
N05AE04	ziprasidone	C0021311	infection	1	[P07550]	DRUG	0.499995859
L04AA13	leflunomide	C0006826	cancer	7	[P03956, P10632, P10275, P05177, Q14289, P35869, P09917]	DRUG	0.019028106
G02CB03	cabergoline	C0006826	cancer	1	[P08684]	DRUG	0.499995859
C10AA01	simvastatin	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.030408848
N02CC01	sumatriptan	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.053091591
N06AB04	citalopram	C0009319	colitis	3	[P08183, P31645, P46098]	DRUG	0.021871238
N06BA09	atomoxetine	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.027818585
A03BA01	atropine	C0027051	myocardial infarction	2	[P06276, P05177]	DRUG	0.178569817
N02CA01	dihydroergotamine	C0020517	hypersensitivity	4	[P41595, Q01959, P35367, P25021]	DRUG	0.001609914
L01DB06	idarubicin	C0085669	acute leukemia	2	[P11388, P33527]	DRUG	0.030408848
L02BB01	flutamide	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.223025539
N02CC01	sumatriptan	C0027651	tumor	18	[Q9UNQ0, P04798, Q16678, P08684, P03372, P08183, Q92731, P14061, P46721, P05181, P05177, P10275, P20813, P20815, Q13639, P35348, P07550, P13945]	DRUG	0.319930306
N03AE01	clonazepam	C0001969	drunk	2	[P47869, P21397]	DRUG_AND_METABOLITE	0.008887027
G04BE08	tadalafil	C0456909	blindness	1	[P35913]	DRUG	0.058976887
A03BA01	atropine	C1456784	paranoia	1	[P05177]	DRUG	0.02394431
H02AB02	dexamethasone	C0018681	headache	1	[P35228]	DRUG_AND_METABOLITE	0.060781766
N05BA01	diazepam	C0033975	psychosis	1	[P08908]	DRUG	0.169250637
N02CC01	sumatriptan	C0010709	cyst	10	[P05177, P08183, P03372, Q92731, Q9UNQ0, P20815, P05181, Q16678, P04798, P10275]	METABOLITE	0.152183766
C08DA01	verapamil	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.018867664
M01AH03	valdecoxib	C0009319	colitis	5	[P00918, P31645, P35354, P46098, P41595]	DRUG_AND_METABOLITE	0.009190408
C09AA06	quinapril	C0035078	renal failure	1	[P12821]	DRUG_AND_METABOLITE	0.027308789
N03AF01	carbamazepine	C0035078	renal failure	1	[P08183]	DRUG	0.117247144
G03DA04	progesterone	C0151798	hepatic necrosis	2	[Q96RI1, P08684]	DRUG_AND_METABOLITE	0.188845309
N06AB03	fluoxetine	C0010709	cyst	7	[P05177, P08183, Q12809, P20815, P05181, P23975, P10275]	METABOLITE	0.386449546
J05AF03	zalcitabine	C0231528	myalgia	1	[O00142]	METABOLITE	0.120607843
H02AB06	prednisolone	C0020456	hyperglycemia	1	[P07148]	DRUG_AND_METABOLITE	0.099143217
A10BX03	nateglinide	C0023895	liver disease	2	[P37231, P08684]	DRUG_AND_METABOLITE	0.019381901
N04BC05	pramipexole	C0020538	hypertension	11	[P35348, P07550, P21728, O15244, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG	3.83447E-06
C09CA01	losartan	C0231749	knee pain	1	[Q08499]	DRUG	0.019028106
N04BC05	pramipexole	C0020550	hyperthyroidism	1	[P07550]	DRUG	0.126592962
C01BB01	lidocaine	C0025637	methemoglobinemia	1	[P05177]	DRUG	0.027162705
N06AA06	trimipramine	C0018681	headache	2	[P05362, P29475]	METABOLITE	0.031044109
N04BX02	entacapone	C0020538	hypertension	1	[P21964]	DRUG_AND_METABOLITE	0.077866045
M01AB15	ketorolac	C0018944	hematoma	1	[P11712]	DRUG	0.057088716
M01AB08	etodolac	C0017152	gastritis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.004954116
N04BC04	ropinirole	C1456784	paranoia	1	[P05177]	DRUG	0.02394431
P01AX06	atovaquone	C0020456	hyperglycemia	1	[P42898]	METABOLITE	0.302543222
N06AA04	clomipramine	C0010709	cyst	13	[P05177, P32238, P08183, P04156, P09211, Q12809, P30874, P32239, P05181, P23975, P17252, P29475, P36544]	METABOLITE	0.487166166
C10AA06	cerivastatin	C0026848	myopathy	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.096195732
C09CA07	telmisartan	C0018802	congestive heart failure	2	[P30556, P37231]	DRUG	0.009779478
A05AA02	ursodeoxycholic acid	C0010709	cyst	2	[Q92887, P05181]	DRUG_AND_METABOLITE	0.364303399
J01AA08	minocycline	C0013404	dyspnea	1	[P01584]	DRUG	0.052242123
G02CB01	bromocriptine	C0020538	hypertension	10	[P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG	0.000228904
J01MA01	ofloxacin	C0024312	lymphopenia	1	[Q92887]	DRUG_AND_METABOLITE	0.036928011
S01AA14	penicillin G	C0024198	Lyme Disease	1	[Q16539]	METABOLITE	0.101130087
N05AH04	quetiapine	C0027059	myocarditis	2	[Q12809, P08588]	DRUG	0.094244523
N04BC04	ropinirole	C0010054	coronary artery disease	1	[P08684]	DRUG	0.273737901
N07AX01	pilocarpine	C0020569	salivary gland enlargement	1	[P20309]	DRUG	0.050504261
M04AB01	probenecid	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.012163276
N03AG01	valproic acid	C0022658	nephropathy	1	[P23219]	DRUG	0.204622921
L02BG06	exemestane	C0151744	myocardial ischemia	1	[Q12809]	METABOLITE	0.036939077
A05AA02	ursodeoxycholic acid	C0021311	infection	2	[P11473, Q96RI1]	DRUG_AND_METABOLITE	0.170818616
C09AA08	cilazapril	C0018801	heart failure	1	[P12821]	DRUG	0.035667691
C10AA02	lovastatin	C0020517	hypersensitivity	2	[P05362, P29475]	METABOLITE	0.219047785
J01EA01	trimethoprim	C0002888	megaloblastic anemia	1	[P00374]	DRUG_AND_METABOLITE	0.023643559
N06AB04	citalopram	C0018790	cardiac arrest	1	[Q12809]	DRUG	0.063596471
N07XX02	riluzole	C0009806	constipation	1	[Q14524]	DRUG	0.025719012
N06AB04	citalopram	C0018799	heart disease	4	[Q12809, P31645, P08588, P20813]	DRUG	0.012929544
N05AD01	haloperidol	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.218869626
M03BX08	cyclobenzaprine	C0231218	malaise	1	[Q8NER1]	DRUG	0.044322867
R03DC03	montelukast	C0023895	liver disease	1	[P08684]	DRUG_AND_METABOLITE	0.0793927
C07AB07	bisoprolol	C0004096	asthma	1	[P07550]	DRUG_AND_METABOLITE	0.105539171
L01XE01	imatinib	C0243026	sepsis	3	[P28482, P27361, Q15746]	DRUG	0.372433478
N02CC01	sumatriptan	C0242422	Parkinson	6	[P05181, P08183, P50406, P08908, Q92731, P14416]	DRUG	0.001906972
N06AA17	amoxapine	C0027051	myocardial infarction	5	[P21554, P07550, P31645, P08588, P18089]	METABOLITE	0.050504261
N02CA01	dihydroergotamine	C0006266	bronchospasm	5	[P07550, P43115, P11229, P20309, O94956]	DRUG	0.050531857
C08CA01	amlodipine	C0023530	leukopenia	1	[P08183]	DRUG	0.072104339
N02AX02	tramadol	C0004096	asthma	1	[P20309]	DRUG	0.210510758
N02AX02	tramadol	C0004093	asthenia	1	[P31645]	DRUG_AND_METABOLITE	0.027162705
N05AH03	olanzapine	C0003873	rheumatoid arthritis	3	[P13945, P25103, P07550]	DRUG_AND_METABOLITE	0.34144738
M01AH03	valdecoxib	C0021311	infection	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.468959957
A04AD12	aprepitant	C0017168	gastroesophageal reflux	1	[P33261]	DRUG_AND_METABOLITE	0.023338897
N06AB04	citalopram	C0018801	heart failure	1	[Q12809]	DRUG	0.120354288
C01EB03	indomethacin	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.017771337
N05AB06	trifluoperazine	C0024141	lupus	1	[P05362]	METABOLITE	0.497068996
J01BA01	chloramphenicol	C0014356	enterocolitis	1	[P08174]	DRUG_AND_METABOLITE	0.040204533
A02BC01	omeprazole	C0003873	rheumatoid arthritis	4	[Q8NER1, P05177, P05023, P04798]	DRUG_AND_METABOLITE	0.064383243
C09AA08	cilazapril	C0018799	heart disease	1	[P12821]	DRUG	0.080618312
A02BA01	cimetidine	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.000853923
N07XX02	riluzole	C0428977	bradycardia	1	[Q14524]	DRUG	0.013961737
N05AX12	aripiprazole	C0037763	spasm	2	[P14867, P21918]	DRUG_AND_METABOLITE	0.009993013
M01AB15	ketorolac	C0018834	heartburn	1	[P23219]	DRUG	0.025394378
R06AX02	cyproheptadine	C0011991	diarrhea	2	[P46098, A5X5Y0]	METABOLITE	0.015143969
N05BE01	buspirone	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	METABOLITE	0.000107249
C03CA01	furosemide	C0002871	anemia	1	[P02768]	DRUG	0.105422145
N05AX08	risperidone	C0022408	arthrosis	1	[Q9H3N8]	DRUG_AND_METABOLITE	0.280440649
N02AA01	morphine	C0004096	asthma	1	[P23219]	DRUG	0.369658864
N02AA01	morphine	C0004093	asthenia	1	[P31645]	METABOLITE	0.049355201
N05AH03	olanzapine	C0242422	Parkinson	7	[P21917, Q01959, P50406, P08908, P31645, P14416, P35462]	DRUG	0.001345197
C09AA04	perindopril	C0085096	peripheral vascular disorder	1	[P12821]	DRUG_AND_METABOLITE	0.037159733
D08AC02	chlorhexidine	C0041582	ulcer	1	[P14780]	DRUG	0.019687894
L01BA01	methotrexate	C0040046	thrombophlebitis	1	[P42898]	DRUG	0.119381023
A05AA02	ursodeoxycholic acid	C0010692	cystitis	1	[P11473]	METABOLITE	0.044574807
N06AB03	fluoxetine	C0027051	myocardial infarction	8	[Q08499, P10275, P11712, P33261, P31645, P05177, P08588, P18089]	DRUG	0.003365937
N05AA01	chlorpromazine	C0024141	lupus	1	[P05362]	METABOLITE	0.497068996
A05AA02	ursodeoxycholic acid	C0033860	psoriasis	1	[P11473]	METABOLITE	0.128968454
C09CA01	losartan	C0151908	dry skin	1	[Q07343]	DRUG	0.137534347
N04BC05	pramipexole	C0033578	prostate neoplasia	3	[P23975, P35348, P07550]	DRUG	0.499995859
C10AA05	atorvastatin	C0026848	myopathy	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.112841395
M01AB08	etodolac	C0020538	hypertension	2	[P11712, P19793]	DRUG	0.060428908
A02BC04	rabeprazole	C0149931	migraine	2	[P50993, P08684]	DRUG_AND_METABOLITE	0.029660789
P01BC02	mefloquine	C0039070	syncope	1	[P29274]	DRUG	0.02023865
G02CB01	bromocriptine	C0032914	toxemia of pregnancy	2	[P07550, P36544]	DRUG	0.160679998
N05AH04	quetiapine	C0013146	abuse	1	[P41595]	DRUG_AND_METABOLITE	0.040753047
B05BC01	mannitol	C0020517	hypersensitivity	3	[P29475, P10144, P35247]	METABOLITE	0.031369584
B05BC01	mannitol	C0020538	hypertension	6	[P29460, P27487, P11226, P61626, P29475, P01008]	METABOLITE	0.112949868
N05AX08	risperidone	C0039503	tendinitis	1	[P35408]	DRUG_AND_METABOLITE	0.017636497
N05AH03	olanzapine	C1527304	allergic reaction	3	[P41595, Q01959, P35367]	DRUG_AND_METABOLITE	0.006558306
N02AX02	tramadol	C0011603	dermatitis	1	[P31645]	DRUG_AND_METABOLITE	0.176247974
C03DB01	amiloride	C0042024	urinary incontinence	2	[P08172, P28223]	DRUG	0.008039887
C09AA01	captopril	C0004093	asthenia	1	[P12821]	DRUG	0.035047926
N02AX02	tramadol	C0011615	atopic dermatitis	1	[P31645]	DRUG_AND_METABOLITE	0.134281172
H02AB02	dexamethasone	C0029456	osteoporosis	5	[P11511, P05093, P08684, P04798, P10275]	DRUG_AND_METABOLITE	0.000304016
G03DA04	progesterone	C0004096	asthma	3	[P04150, O94956, P33527]	DRUG_AND_METABOLITE	0.341937988
G03DA04	progesterone	C0004093	asthenia	3	[P08185, P28223, P04150]	DRUG_AND_METABOLITE	0.001365729
A02BC04	rabeprazole	C0023530	leukopenia	1	[P08183]	METABOLITE	0.114516617
G03CA03	estradiol	C0018944	hematoma	1	[P11712]	DRUG_AND_METABOLITE	0.159861583
N06BA09	atomoxetine	C0231528	myalgia	2	[P17252, P29475]	DRUG	0.056501401
C07AB02	metoprolol	C0018802	congestive heart failure	1	[P07550]	DRUG_AND_METABOLITE	0.081691579
N04BX01	tolcapone	C0013395	Dyspepsia	1	[P21964]	DRUG	0.020619485
A02BC02	pantoprazole	C0017152	gastritis	1	[P20648]	DRUG_AND_METABOLITE	0.088180739
A04AA01	ondansetron	C0013384	dyskinesia	2	[P14416, P35462]	DRUG	0.054232974
N04BX01	tolcapone	C0013384	dyskinesia	1	[P21964]	DRUG	0.058976887
N06BA04	methylphenidate	C0149931	migraine	4	[P28223, P21917, P31645, P28335]	DRUG_AND_METABOLITE	0.000250554
L04AA13	leflunomide	C0021311	infection	1	[P09917]	DRUG	0.325990764
N03AG06	tiagabine	C0042024	urinary incontinence	1	[P08172]	DRUG	0.051898369
A07EA06	budesonide	C0152459	striae	1	[P35354]	METABOLITE	0.136392432
N06DA02	donepezil	C0242184	hypoxia	1	[P05067]	DRUG	0.195446067
L04AX04	lenalidomide	C0162297	respiratory arrest	1	[P19838]	DRUG	0.046871884
N05AB06	trifluoperazine	C0042109	urticaria	2	[P07550, P09917]	DRUG	0.053146369
A03FA02	cisapride	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.035022163
M01AC01	piroxicam	C0027726	nephrotic syndrome	1	[P35354]	DRUG_AND_METABOLITE	0.102854888
N04BD01	selegiline	C0442874	neuropathy	1	[P08183]	DRUG	0.155477655
A01AC01	triamcinolone	C0020538	hypertension	1	[P04150]	DRUG	0.077866045
J05AF06	abacavir	C0023530	leukopenia	1	[P22309]	DRUG	0.027162705
M01AE03	ketoprofen	C0030920	peptic ulcer	3	[P35354, P10145, P23219]	DRUG	0.000405161
J01AA08	minocycline	C0017574	gingivitis	1	[P01584]	DRUG	0.035667691
A04AA01	ondansetron	C0013604	edema	1	[P08588]	DRUG	0.067326521
A02BC02	pantoprazole	C0036572	seizures	1	[P50993]	DRUG_AND_METABOLITE	0.062319473
C07AB02	metoprolol	C0018790	cardiac arrest	2	[Q13936, P07550]	DRUG_AND_METABOLITE	0.002797595
N06AA21	maprotiline	C0027051	myocardial infarction	2	[P31645, P05177]	DRUG	0.123597305
M01AB08	etodolac	C0020456	hyperglycemia	1	[P35354]	DRUG_AND_METABOLITE	0.063596471
N02AX02	tramadol	C0027051	myocardial infarction	1	[P31645]	DRUG_AND_METABOLITE	0.233918541
N06BA09	atomoxetine	C0014394	enuresis	2	[P28223, P29475]	DRUG	0.010306771
N06AA02	imipramine	C0012833	dizziness	1	[P29274]	METABOLITE	0.053008495
N02AA03	hydromorphone	C0001824	agranulocytosis	2	[O60656, P08183]	DRUG_AND_METABOLITE	0.011339904
C10AA05	atorvastatin	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.0608928
N06AA04	clomipramine	C1456784	paranoia	1	[P05177]	DRUG_AND_METABOLITE	0.059946991
J01MA01	ofloxacin	C1456784	paranoia	1	[P05177]	DRUG_AND_METABOLITE	0.01884128
G03CA03	estradiol	C0010709	cyst	20	[P05177, P32238, P08183, P03372, Q92887, Q92731, P33527, P08842, Q9UNQ0, P32239, P20815, P05181, Q16678, P50225, P22309, P04798, P10275, P21964, P11474, O15438]	DRUG	0.045033357
M01AE02	naproxen	C0032285	pneumonia	1	[P35354]	DRUG	0.214459208
N06AA09	amitriptyline	C0003864	arthritis	1	[Q9H3N8]	DRUG	0.379665802
N02AA01	morphine	C0004134	ataxia	1	[P35498]	DRUG_AND_METABOLITE	0.10852861
D07AB10	alclometasone	C0021311	infection	1	[P04150]	DRUG_AND_METABOLITE	0.203948616
N04BC02	pergolide	C0042024	urinary incontinence	2	[P28223, P21917]	DRUG_AND_METABOLITE	0.003874925
M03BX01	baclofen	C0009951	convulsions	8	[P35498, P18507, Q9UBS5, Q99250, Q9NY46, P28472, O75899, P47870]	DRUG	1.48976E-07
J01AA07	tetracycline	C0002871	anemia	2	[P02768, O14746]	DRUG_AND_METABOLITE	0.01337726
M01AH03	valdecoxib	C0033975	psychosis	5	[P35462, P28223, P28222, P31645, P08908]	DRUG_AND_METABOLITE	0.0002856
A05AA02	ursodeoxycholic acid	C0027651	tumor	10	[O75469, Q92887, P52895, P11473, Q96RI1, P46721, P05181, P06746, O15439, Q13133]	METABOLITE	0.024401265
L04AA06	mycophenolic acid	C0006826	cancer	2	[P37231, P22309]	DRUG_AND_METABOLITE	0.173402837
L04AA06	mycophenolic acid	C0699893	skin carcinoma	1	[P37231]	DRUG_AND_METABOLITE	0.187384674
A02BC04	rabeprazole	C0023890	cirrhosis	1	[P08684]	DRUG_AND_METABOLITE	0.288172984
G03XC01	raloxifene	C0021311	infection	1	[P03372]	DRUG	0.372691909
A02BC02	pantoprazole	C0031099	periodontitis	1	[P04798]	METABOLITE	0.074342707
L02BG06	exemestane	C0029456	osteoporosis	3	[P11511, P08684, P10275]	METABOLITE	0.000171611
N06AB03	fluoxetine	C0039231	tachycardia	1	[P08588]	DRUG	0.05003687
N06AB04	citalopram	C0018621	seasonal allergic rhinitis	2	[Q01959, P35367]	DRUG	0.019646445
L01XE03	erlotinib	C0007784	cerebral hemorrhage	2	[P24723, O60674]	DRUG_AND_METABOLITE	0.480226741
N06DA03	rivastigmine	C1458155	breast neoplasm	1	[P08684]	DRUG	0.443800819
N06DA02	donepezil	C0030305	pancreatitis	1	[P49682]	DRUG	0.090729349
N02AA03	hydromorphone	C0017152	gastritis	1	[P23219]	DRUG	0.106462706
L02BG06	exemestane	C0029408	osteoarthritis	1	[P11511]	DRUG	0.076302208
C09CA06	candesartan	C0013274	patent ductus arteriosus	1	[P30556]	DRUG_AND_METABOLITE	0.009521978
C07AB02	metoprolol	C0010054	coronary artery disease	1	[P13945]	DRUG_AND_METABOLITE	0.178569817
C01DA02	nitroglycerin	C0021311	infection	2	[P09211, P37173]	METABOLITE	0.22092564
M01AE09	flurbiprofen	C0027947	neutropenia	4	[P16662, O60656, P22309, P08246]	DRUG	2.08794E-05
N07XX02	riluzole	C0004134	ataxia	1	[O00555]	DRUG	0.063596471
A10BB09	gliclazide	C0040584	tracheitis	1	[P15692]	DRUG	0.004506529
N06AA04	clomipramine	C0024299	lymphoma	1	[P08183]	DRUG_AND_METABOLITE	0.49550634
L04AA06	mycophenolic acid	C0020538	hypertension	1	[P37231]	DRUG_AND_METABOLITE	0.106277208
L04AA06	mycophenolic acid	C0020542	pulmonary hypertension	1	[P37231]	DRUG_AND_METABOLITE	0.033019051
N06AX21	duloxetine	C0009319	colitis	5	[P08183, P31645, P35354, P46098, P41595]	DRUG_AND_METABOLITE	0.051513979
A02BA02	ranitidine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.05003687
C09AA10	trandolapril	C0085096	peripheral vascular disorder	1	[P12821]	DRUG_AND_METABOLITE	0.037159733
N05AH04	quetiapine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.115784639
C08DA01	verapamil	C0006266	bronchospasm	1	[P33527]	DRUG	0.439336515
C03BA11	indapamide	C0004238	atrial fibrillation	2	[P51787, P15382]	DRUG_AND_METABOLITE	0.012933575
C03DB01	amiloride	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.005356651
C09AA03	lisinopril	C0006266	bronchospasm	1	[P12821]	DRUG	0.092356341
J01AA08	minocycline	C0017675	glossitis	1	[P01584]	DRUG	0.008782102
P01AX06	atovaquone	C0020517	hypersensitivity	6	[P42898, Q01959, P50135, P35367, P25021, Q9H3N8]	METABOLITE	0.000714178
G04BE03	sildenafil	C0004096	asthma	1	[Q08499]	DRUG	0.36509052
L02BG04	letrozole	C0029456	osteoporosis	2	[P11511, P08684]	DRUG	0.002346816
N04BC02	pergolide	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.001465281
N06AX11	mirtazapine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG	0
R06AX02	cyproheptadine	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.005535519
N02BA11	diflunisal	C0013395	Dyspepsia	1	[P23219]	DRUG	0.022511552
C10AA05	atorvastatin	C0003123	anorexia	1	[P27487]	DRUG_AND_METABOLITE	0.065940698
C09AA02	enalapril	C0016199	flank pain	1	[P12821]	DRUG_AND_METABOLITE	0.004887659
A10BB09	gliclazide	C0020538	hypertension	2	[P15692, P11712]	DRUG	0.018841569
N06AX16	venlafaxine	C0007097	carcinoma	11	[P08183, P61278, P07550, P32239, P17252, Q9Y5N1, P08684, P30532, P32238, P23975, P29475]	DRUG	0.499995859
N02AX02	tramadol	C0011849	diabetes mellitus	2	[O15245, P08684]	DRUG	0.064806189
N03AX16	pregabalin	C1458155	breast neoplasm	1	[Q01650]	DRUG	0.470911096
L01XE01	imatinib	C0009951	convulsions	4	[P78368, P08183, O15146, P53355]	DRUG	0.394555908
L01XX05	hydroxyurea	C0041582	ulcer	1	[P14780]	METABOLITE	0.019687894
N05AH04	quetiapine	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.011475973
R06AX17	ketotifen	C1527304	allergic reaction	2	[P41595, P35367]	DRUG	0.014253709
M03BX08	cyclobenzaprine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.015956935
L01BA01	methotrexate	C0024115	lung disorder	2	[P08183, P47989]	DRUG	0.138656555
N05AH03	olanzapine	C0242184	hypoxia	3	[P08172, P11229, Q12809]	DRUG_AND_METABOLITE	0.218249254
N04BC02	pergolide	C0011603	dermatitis	3	[P07550, P28223, P08908]	DRUG_AND_METABOLITE	0.040204533
N07XX02	riluzole	C0004238	atrial fibrillation	1	[Q14524]	DRUG	0.073397504
C03DB02	triamterene	C0040034	thrombocytopenia	1	[O60674]	DRUG	0.040204533
L01XE01	imatinib	C0032285	pneumonia	2	[P43405, P20783]	DRUG	0.360279874
A08AA10	sibutramine	C0149931	migraine	5	[P28223, P21917, P31645, P08684, P28335]	DRUG_AND_METABOLITE	1.16771E-06
P01AX06	atovaquone	C0020615	hypoglycemia	2	[P48506, P07550]	METABOLITE	0.076638319
J01MA01	ofloxacin	C0024117	COPD	1	[P05177]	DRUG_AND_METABOLITE	0.179551964
G04BE03	sildenafil	C0684249	lung cancer	8	[P05181, O15439, Q5T3U5, P11712, P04798, P33261, P08684, P20815]	DRUG	0.015844591
N04BD01	selegiline	C0878544	cardiomyopathy	2	[O76082, P08588]	METABOLITE	0.057524345
C09XA02	aliskiren	C0015230	rash	1	[P14091]	DRUG_AND_METABOLITE	0.078558694
N06BA01	amphetamine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.009882091
J01FA01	erythromycin	C0151744	myocardial ischemia	1	[Q12809]	DRUG	0.07026785
C09AA01	captopril	C0008031	chest pain	1	[P02768]	DRUG	0.016701405
C09XA02	aliskiren	C0085649	peripheral edema	1	[P00797]	DRUG_AND_METABOLITE	0.013961737
N06AA02	imipramine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.098727853
A02BC02	pantoprazole	C0017601	glaucoma	1	[Q16678]	METABOLITE	0.07985866
N06BA01	amphetamine	C0014518	toxic epidermal necrolysis	1	[P14780]	METABOLITE	0.044491261
A10BB09	gliclazide	C0020615	hypoglycemia	2	[Q09428, P15692]	DRUG	0.000761992
N06AA04	clomipramine	C0024902	breast pain	1	[Q8NER1]	METABOLITE	0.050141944
J02AC03	voriconazole	C0033860	psoriasis	1	[P00918]	METABOLITE	0.105539171
N05AX08	risperidone	C0022104	irritable bowel syndrome	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.003187431
J05AF02	didanosine	C0001122	acidosis	1	[P54098]	METABOLITE	0.052994355
G03DA04	progesterone	C0085649	peripheral edema	1	[P08588]	METABOLITE	0.082202439
C07AB02	metoprolol	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG_AND_METABOLITE	3.52831E-05
B01AC04	clopidogrel	C0020538	hypertension	2	[P20815, P11712]	DRUG	0.034299094
N04BC05	pramipexole	C0004096	asthma	3	[P07550, P11229, P20309]	DRUG	0.114580337
N04BC05	pramipexole	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.00486818
C07AA07	sotalol	C0013604	edema	1	[P08588]	DRUG	0.02023865
N04BD01	selegiline	C0085649	peripheral edema	1	[P08588]	METABOLITE	0.047831182
P02CA03	albendazole	C0015230	rash	1	[P08908]	DRUG	0.114580337
N06AB04	citalopram	C0014130	Endocrine Disorders	1	[Q12809]	DRUG	0.266243108
J01MA01	ofloxacin	C0011991	diarrhea	1	[Q92887]	DRUG_AND_METABOLITE	0.040283843
N04BC05	pramipexole	C0152029	sinus congestion	3	[P25021, P35367, P08588]	DRUG	0.012781928
N03AF01	carbamazepine	C0027051	myocardial infarction	5	[P35354, P11712, P33261, P23219, P05177]	DRUG	0.013159264
D05BB02	acitretin	C0020473	hyperlipidemia	1	[P23219]	METABOLITE	0.117247144
L01XE01	imatinib	C0017601	glaucoma	1	[O43570]	DRUG	0.378216014
N03AA03	primidone	C0001824	agranulocytosis	2	[Q92887, P08183]	METABOLITE	0.015405718
N04BD01	selegiline	C0003123	anorexia	7	[P28223, P28335, P21397, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	9.85161E-08
M01AG01	mefenamic acid	C0004093	asthenia	1	[P35354]	DRUG	0.021841092
M01AG01	mefenamic acid	C0004096	asthma	2	[P35354, P23219]	DRUG	0.04394482
N03AF01	carbamazepine	C0030305	pancreatitis	2	[Q99895, P35354]	METABOLITE	0.045442566
R01AD01	beclomethasone	C0018681	headache	1	[P35228]	DRUG_AND_METABOLITE	0.05799926
M03BX02	tizanidine	C0018790	cardiac arrest	1	[P18089]	DRUG	0.024401265
N04BC04	ropinirole	C0014130	Endocrine Disorders	1	[Q13639]	DRUG	0.271879838
N03AF01	carbamazepine	C0005586	bipolar disorder	2	[P21728, P04156]	DRUG	0.044892405
C09AA10	trandolapril	C0020473	hyperlipidemia	1	[P12821]	DRUG_AND_METABOLITE	0.036521819
C09AA08	cilazapril	C0039231	tachycardia	1	[P12821]	DRUG	0.00976001
L01XE01	imatinib	C0151798	hepatic necrosis	2	[Q13177, P08684]	DRUG	0.457085976
N06BA07	modafinil	C0033975	psychosis	1	[P21964]	DRUG	0.066476119
N05AX08	risperidone	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.062610213
N06AA04	clomipramine	C0030193	pain	1	[Q8NER1]	METABOLITE	0.086098006
N04BC04	ropinirole	C0006826	cancer	2	[P08684, P05177]	DRUG	0.4999421
D06BB10	imiquimod	C0021311	infection	1	[Q9NYK1]	DRUG	0.155436654
N04BD01	selegiline	C0042024	urinary incontinence	1	[P28223]	DRUG_AND_METABOLITE	0.064439777
N06AA01	desipramine	C0428982	nodal tachycardia	4	[O76082, Q12809, P08588, P07550]	DRUG	0.010534938
C07AG02	carvedilol	C0011849	diabetes mellitus	7	[P15692, P11712, P19320, P08684, P13945, P07550, P16860]	DRUG	9.13424E-05
J05AE05	amprenavir	C0011849	diabetes mellitus	3	[P11712, P08684, P10632]	DRUG	0.013399503
M04AA01	allopurinol	C0031117	peripheral neuropathy	1	[P60891]	METABOLITE	0.098574245
N06AX11	mirtazapine	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG	1.38448E-06
N06AX05	trazodone	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG_AND_METABOLITE	0.168431086
C07AA05	propranolol	C0024141	lupus	1	[P04798]	DRUG	0.339889802
D01AC02	miconazole	C0015230	rash	1	[P09601]	DRUG	0.313135213
N01AH01	fentanyl	C0149931	migraine	3	[P28223, P08684, P28335]	DRUG	0.000406384
J01AA07	tetracycline	C0002792	anaphylaxis	1	[P08253]	DRUG_AND_METABOLITE	0.056501401
B01AC05	ticlopidine	C0024141	lupus	2	[P04798, Q9H244]	DRUG_AND_METABOLITE	0.104717888
L04AX04	lenalidomide	C0030196	Pain in limb	1	[Q08499]	DRUG	0.016169699
L04AX04	lenalidomide	C0030193	pain	1	[Q08499]	DRUG	0.027162705
L04AX02	thalidomide	C0149931	migraine	1	[P01375]	DRUG	0.236166005
A02BC03	lansoprazole	C0231528	myalgia	1	[Q9Y6L6]	METABOLITE	0.107464244
N04BC05	pramipexole	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG	9.71969E-06
N04BX01	tolcapone	C0020538	hypertension	3	[P27487, P11712, P21964]	DRUG	0.016167337
M01AG01	mefenamic acid	C0030305	pancreatitis	1	[P35354]	DRUG	0.081034147
A10BG03	pioglitazone	C0019158	hepatitis	2	[P23219, P11509]	DRUG	0.018096702
N01BB01	bupivacaine	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.010911483
A10BX03	nateglinide	C0015230	rash	1	[P37231]	DRUG_AND_METABOLITE	0.134281172
N04BD01	selegiline	C0085584	encephalopathy	1	[P08183]	DRUG	0.139973976
M01AH03	valdecoxib	C0029927	ovarian cyst	1	[P35354]	DRUG_AND_METABOLITE	0.109539086
N05AX08	risperidone	C0013595	eczema	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG_AND_METABOLITE	0.002642872
N05BE01	buspirone	C0009806	constipation	3	[P46098, P41595, P31645]	METABOLITE	0.000374019
C09AA08	cilazapril	C0021311	infection	1	[P12821]	DRUG	0.155436654
L04AA06	mycophenolic acid	C0020433	bilirubinemia	1	[P22309]	DRUG_AND_METABOLITE	0.018638775
N07XX02	riluzole	C0149931	migraine	1	[O00555]	DRUG	0.06259756
N06AA12	doxepin	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG_AND_METABOLITE	7.22458E-05
N01AH01	fentanyl	C0032584	polyps	3	[P08183, Q12809, P20815]	DRUG	0.268626986
J01MA01	ofloxacin	C0011849	diabetes mellitus	2	[P08684, P02768]	METABOLITE	0.092998912
L04AA06	mycophenolic acid	C0020456	hyperglycemia	1	[P37231]	DRUG_AND_METABOLITE	0.035667691
N02AA03	hydromorphone	C0149931	migraine	4	[P21917, P31645, P35498, P08684]	DRUG_AND_METABOLITE	0.000195869
N02CC01	sumatriptan	C0009319	colitis	4	[P08183, A5X5Y0, P46098, P41595]	DRUG	0.021406141
L04AA06	mycophenolic acid	C0020473	hyperlipidemia	1	[P37231]	DRUG_AND_METABOLITE	0.041540814
H02AB02	dexamethasone	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.101467526
D01AC08	ketoconazole	C0023530	leukopenia	1	[P08183]	DRUG	0.102405075
D05BB02	acitretin	C0020538	hypertension	3	[P11511, P19793, P48443]	DRUG_AND_METABOLITE	0.051924825
J05AF03	zalcitabine	C0036572	seizures	1	[P54098]	METABOLITE	0.068205178
M01AE03	ketoprofen	C0030305	pancreatitis	1	[P35354]	DRUG	0.116501515
N05AA01	chlorpromazine	C0012833	dizziness	1	[P29274]	DRUG	0.057987175
N06AB04	citalopram	C0018524	hallucinations	1	[P08183]	DRUG	0.112949868
R03AC12	salmeterol	C0149931	migraine	1	[P08684]	DRUG	0.037810863
C10AA06	cerivastatin	C0022346	jaundice	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.017783546
N04BC05	pramipexole	C0152128	drug withdrawal	1	[P14416]	DRUG	0.020240076
L01XE03	erlotinib	C0085605	hepatic failure	1	[P17948]	DRUG_AND_METABOLITE	0.204160347
A03FA02	cisapride	C0006266	bronchospasm	1	[P07550]	DRUG	0.378573515
C07AA12	nadolol	C0031511	pheochromocytoma	1	[P08183]	DRUG	0.302797933
N06AX21	duloxetine	C0017152	gastritis	2	[P23219, P35354]	METABOLITE	0.075726737
J05AE01	saquinavir	C0442874	neuropathy	1	[P08183]	DRUG	0.098169818
L01AB01	busulfan	C0004096	asthma	1	[P11766]	METABOLITE	0.168492591
N06AB08	fluvoxamine	C0042024	urinary incontinence	1	[P28223]	DRUG_AND_METABOLITE	0.044396476
N06AA09	amitriptyline	C0038454	cerebrovascular accident	3	[P05362, P28223, P07550]	DRUG_AND_METABOLITE	0.175999026
N06AX21	duloxetine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000968869
C01BD01	amiodarone	C0428977	bradycardia	1	[Q14524]	DRUG	0.019028106
C09AA09	fosinopril	C0010054	coronary artery disease	1	[P12821]	DRUG	0.062423964
C09CA07	telmisartan	C0039231	tachycardia	1	[P30556]	DRUG	0.020619485
L04AA06	mycophenolic acid	C0085096	peripheral vascular disorder	1	[P37231]	DRUG_AND_METABOLITE	0.042510997
M03CA01	dantrolene	C0012833	dizziness	1	[Q92736]	DRUG	0.006114053
N06AX16	venlafaxine	C0018681	headache	1	[P29475]	DRUG	0.100095257
L01XE01	imatinib	C0151908	dry skin	1	[Q9UKE5]	DRUG	0.485850957
C10AA02	lovastatin	C0016382	flushing	1	[P05091]	METABOLITE	0.038976603
C01BA01	quinidine	C0004134	ataxia	1	[P35498]	DRUG	0.13428209
N05AA01	chlorpromazine	C0020456	hyperglycemia	2	[P35354, Q9Y210]	METABOLITE	0.143199044
C08CA05	nifedipine	C0020517	hypersensitivity	1	[O75762]	DRUG	0.154141455
R03AC13	formoterol	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.00015919
J01MA02	ciprofloxacin	C0020538	hypertension	1	[P20815]	DRUG	0.222055843
N02AA01	morphine	C0013146	abuse	1	[P21964]	DRUG_AND_METABOLITE	0.028123725
N04BC04	ropinirole	C0022104	irritable bowel syndrome	2	[P46098, P41595]	DRUG	0.008079398
N05AX08	risperidone	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.011475973
G04CA01	alfuzosin	C0010054	coronary artery disease	1	[P08684]	DRUG	0.07578866
A02BC03	lansoprazole	C0017152	gastritis	1	[P20648]	DRUG_AND_METABOLITE	0.085994838
N05AD01	haloperidol	C0003811	arrhythmia	1	[O95259]	DRUG	0.09505443
R01AD01	beclomethasone	C0017601	glaucoma	2	[Q16678, P04150]	DRUG_AND_METABOLITE	0.017299934
J05AE01	saquinavir	C0020541	portal hypertension	2	[P20815, P11712]	DRUG	0.10877922
J05AE01	saquinavir	C0020538	hypertension	2	[P20815, P11712]	DRUG	0.110503219
H02AB02	dexamethasone	C0002792	anaphylaxis	1	[P35228]	DRUG_AND_METABOLITE	0.088258057
G03BA03	testosterone	C0014130	Endocrine Disorders	4	[Q16678, P50225, P04798, P03372]	METABOLITE	0.118299455
N02CC03	zolmitriptan	C0027051	myocardial infarction	2	[P05177, P18089]	DRUG	0.064837266
A04AA01	ondansetron	C0006266	bronchospasm	4	[P07550, Q15722, P11229, P20309]	DRUG	0.14501301
N05AX08	risperidone	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.082129915
N06DA02	donepezil	C0038358	gastric ulcer	1	[P23219]	DRUG	0.036928011
A02BA01	cimetidine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.085892844
N02BA11	diflunisal	C0008031	chest pain	1	[P02768]	DRUG	0.013399503
G03BA03	testosterone	C0007097	carcinoma	24	[P03372, P06401, P08183, P11474, Q92731, Q9UNQ0, Q5T3U5, P52895, Q16696, P10275, Q16678, P50225, P08842, P42330, P05093, P20815, P10632, P04798, P18405, P08684, P11511, P05177, P31213, P22309]	METABOLITE	0.253958811
L04AX02	thalidomide	C0018802	congestive heart failure	1	[P01375]	DRUG	0.31133469
L04AX02	thalidomide	C0018801	heart failure	1	[P01375]	DRUG	0.31133469
M03BX08	cyclobenzaprine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.00976001
L04AX01	azathioprine	C0023530	leukopenia	1	[P22309]	METABOLITE	0.14059695
J01AA08	minocycline	C0009951	convulsions	4	[P01584, P14780, P04156, P42574]	DRUG	0.002121582
N07BA01	nicotine	C0006266	bronchospasm	2	[P11229, P20309]	DRUG	0.26159789
N05AB04	prochlorperazine	C0031511	pheochromocytoma	2	[Q07820, P23975]	DRUG_AND_METABOLITE	0.475937679
S01ED02	betaxolol	C0018801	heart failure	1	[P07550]	DRUG_AND_METABOLITE	0.088180739
G04CA03	terazosin	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.014025764
C09CA07	telmisartan	C0013595	eczema	2	[P37231, Q07869]	DRUG	0.025746748
L04AX04	lenalidomide	C0030305	pancreatitis	5	[P01375, Q99895, P05181, P04798, P35354]	DRUG	2.90582E-05
N06AB04	citalopram	C0001824	agranulocytosis	1	[P08183]	DRUG	0.06555312
C03DB01	amiloride	C0030305	pancreatitis	1	[P07477]	DRUG	0.222270543
N06AB06	sertraline	C0012813	diverticulitis	1	[P31645]	DRUG_AND_METABOLITE	0.064721996
A10BX02	repaglinide	C0010054	coronary artery disease	2	[P37231, P08684]	DRUG	0.019575297
N06AA06	trimipramine	C0018524	hallucinations	6	[P08183, P36544, P35498, Q99250, P04156, Q9NY46]	DRUG_AND_METABOLITE	0.001281171
M01AC01	piroxicam	C0027051	myocardial infarction	3	[P35354, P11712, P23219]	DRUG_AND_METABOLITE	0.007685869
D10AA02	methylprednisolone	C0017601	glaucoma	1	[P04150]	DRUG_AND_METABOLITE	0.034424934
H02AB06	prednisolone	C0029456	osteoporosis	6	[P03372, P11511, P08684, P10275, P04278, Q92731]	DRUG_AND_METABOLITE	4.25611E-06
M01AH02	rofecoxib	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.185493577
N06AB03	fluoxetine	C0149931	migraine	5	[P28223, P21917, P31645, P08684, P28335]	DRUG_AND_METABOLITE	5.69873E-05
N06AF03	phenelzine	C0036341	schizophrenia	5	[P21397, P04179, P20815, P31645, Q01959]	DRUG	0.013294904
N06AX16	venlafaxine	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	METABOLITE	0.006999028
G04BE09	vardenafil	C0020538	hypertension	2	[P20815, Q08499]	DRUG	0.13345508
L04AX02	thalidomide	C0018681	headache	1	[P01375]	DRUG	0.123905642
N06AA09	amitriptyline	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.019687894
S01AA14	penicillin G	C0242184	hypoxia	5	[Q16790, Q16539, P16050, P46059, Q14524]	DRUG	0.042264359
R06AX02	cyproheptadine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.009652814
C01BC03	propafenone	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.051010927
A07EC01	sulfasalazine	C0006826	cancer	18	[P35354, O15111, P09211, P37231, P05230, P19971, O14965, Q9UNQ0, Q07820, P20815, P05181, P10632, P08684, P23219, Q92887, O14920, P09917, P47989]	METABOLITE	0.000107249
N04BC05	pramipexole	C0600139	prostate cancer	4	[Q9H3N8, Q9Y5N1, P35348, P07550]	DRUG	0.499236835
J05AF01	zidovudine	C0152032	urinary hesitancy	2	[P02768, P05771]	DRUG	0.026275405
C09CA04	irbesartan	C0038454	cerebrovascular accident	1	[P30556]	DRUG_AND_METABOLITE	0.114348668
C09CA02	eprosartan	C0018801	heart failure	2	[P30556, P50052]	DRUG	0.00293069
J01EA01	trimethoprim	C0023530	leukopenia	1	[P08183]	DRUG	0.061653521
N05AH04	quetiapine	C0149931	migraine	5	[P28223, P21917, P31645, P08684, P28335]	DRUG_AND_METABOLITE	0.000125975
N06AB06	sertraline	C0149931	migraine	4	[P28223, P31645, P08684, P28335]	DRUG	0.000178986
M01AC06	meloxicam	C0042109	urticaria	1	[P09917]	DRUG	0.029823411
M01AB05	diclofenac	C0002874	aplastic anemia	1	[P04798]	DRUG	0.232839177
M01AB05	diclofenac	C0002871	anemia	3	[P10145, P02768, P07148]	DRUG	0.013107191
C01BB01	lidocaine	C0009951	convulsions	4	[P35498, P08183, Q99250, Q9NY46]	DRUG	0.006229806
R01AC03	azelastine	C0020538	hypertension	2	[P20815, P11712]	DRUG	0.060428908
A07EA06	budesonide	C0035455	rhinitis	1	[P35228]	METABOLITE	0.100424708
N06DA02	donepezil	C0038454	cerebrovascular accident	2	[P05067, P28223]	DRUG	0.02266211
C03DB01	amiloride	C0015230	rash	5	[P00749, P28223, P08908, P31645, Q9Y271]	DRUG	0.003874925
J05AG01	nevirapine	C0023895	liver disease	1	[P08684]	DRUG	0.089912296
N04AC01	benztropine	C0009806	constipation	1	[P31645]	DRUG_AND_METABOLITE	0.03490134
M03BX08	cyclobenzaprine	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.077843187
C09CA01	losartan	C0040460	Toothache	1	[Q08499]	DRUG	0.019028106
J05AF03	zalcitabine	C0001122	acidosis	1	[P54098]	METABOLITE	0.059084847
N06AX16	venlafaxine	C0035078	renal failure	2	[P08183, P29274]	DRUG_AND_METABOLITE	0.08142718
N06AX11	mirtazapine	C0015230	rash	3	[P28223, P08908, P31645]	DRUG	0.03201379
L02BG03	anastrozole	C0020538	hypertension	4	[P35348, P11511, P11712, P08913]	METABOLITE	0.001111541
M01AB05	diclofenac	C0002878	hemolytic anemia	1	[P22309]	DRUG	0.123730513
M03BX02	tizanidine	C0018801	heart failure	1	[Q9Y2I1]	DRUG	0.045375219
L04AX01	azathioprine	C0023467	AML	1	[P17252]	METABOLITE	0.449802927
C02KX01	bosentan	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.027818585
C10AB05	fenofibrate	C0021311	infection	2	[P37231, Q07869]	DRUG_AND_METABOLITE	0.131621165
J01CA01	ampicillin	C0002871	anemia	1	[P02768]	DRUG_AND_METABOLITE	0.044087091
L01BC06	capecitabine	C0027051	myocardial infarction	3	[P02768, P11712, P05177]	METABOLITE	0.074052753
N05AD01	haloperidol	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.48976E-07
N06AB04	citalopram	C0030305	pancreatitis	1	[P05181]	DRUG	0.157494476
A11CC04	calcitriol	C0042029	urinary tract infection	1	[P11473]	DRUG_AND_METABOLITE	0.013240691
G02CB03	cabergoline	C0033975	psychosis	5	[P35462, P28223, P21917, P28222, P08908]	DRUG	9.02061E-06
R03AC13	formoterol	C0027051	myocardial infarction	5	[P13945, P07550, P11712, P33261, P08588]	DRUG	2.77804E-05
N06AX16	venlafaxine	C0018802	congestive heart failure	2	[Q14524, P07550]	DRUG	0.094301637
H02AB06	prednisolone	C0442874	neuropathy	2	[Q09470, P08183]	DRUG_AND_METABOLITE	0.021299045
N05AH02	clozapine	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.126293414
M01AX01	nabumetone	C0017152	gastritis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.001881731
N06AX16	venlafaxine	C0018801	heart failure	2	[Q14524, P07550]	DRUG	0.094301637
M01AE09	flurbiprofen	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.00348143
N03AB02	phenytoin	C0024299	lymphoma	1	[P08183]	DRUG	0.393925702
N03AF01	carbamazepine	C0010054	coronary artery disease	2	[P08684, P35354]	METABOLITE	0.112841395
C02CA04	doxazosin	C0004093	asthenia	1	[P28223]	METABOLITE	0.035047926
G03DA04	progesterone	C0011570	mental depression	6	[P33261, P08684, P28223, P21397, P08908, P03372]	DRUG_AND_METABOLITE	9.09152E-05
C07AA06	timolol	C0042109	urticaria	1	[P07550]	DRUG	0.035667691
L04AX04	lenalidomide	C0011849	diabetes mellitus	4	[P01375, P11712, P19838, P35354]	DRUG	0.009329478
C08DB01	diltiazem	C0442874	neuropathy	3	[Q9UQD0, Q09470, P08183]	DRUG	0.00360029
L02BG04	letrozole	C0476089	endometrial cancer	2	[P11511, P08684]	DRUG	0.008782102
N05AX12	aripiprazole	C0013595	eczema	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.027175081
G02CB03	cabergoline	C0242422	Parkinson	4	[P21917, P08908, P14416, P35462]	DRUG	0.003355984
A10BX03	nateglinide	C0020615	hypoglycemia	2	[Q09428, P53985]	DRUG_AND_METABOLITE	0.003900351
N02AX02	tramadol	C0027651	tumor	4	[P08684, P20813, P23975, P35348]	DRUG	0.416765961
A02BC03	lansoprazole	C0149931	migraine	2	[P50993, P08684]	DRUG_AND_METABOLITE	0.013399503
N02AA01	morphine	C0013395	Dyspepsia	2	[P23219, P21964]	DRUG_AND_METABOLITE	0.00215595
N04BC05	pramipexole	C0037315	sleep apnea	1	[P31645]	DRUG	0.031415297
J01FA10	azithromycin	C0009951	convulsions	2	[P08183, P33527]	DRUG_AND_METABOLITE	0.040353299
C07AB07	bisoprolol	C0011570	mental depression	1	[P08684]	DRUG	0.031878908
N02AE01	buprenorphine	C0020538	hypertension	4	[P20815, P31645, P11712, P23975]	DRUG	0.013707399
N03AF02	oxcarbazepine	C0021311	infection	1	[Q16548]	DRUG	0.264908626
C01BD01	amiodarone	C0013604	edema	1	[P08588]	DRUG	0.03490134
N06AX16	venlafaxine	C0085762	alcohol abuse	12	[P28223, P31645, P21728, P08908, P35462, P14416, P21397, P08172, Q05586, Q13224, P35372, P25103]	DRUG	0
N05BC01	meprobamate	C1527304	allergic reaction	6	[P42898, Q01959, P50135, P35367, P25021, Q9H3N8]	METABOLITE	0.000221093
A08AA10	sibutramine	C0040517	Gilles de la Tourette syndrome	4	[P14416, Q01959, O95264, P46098]	DRUG	3.59294E-07
N05BC01	meprobamate	C0085649	peripheral edema	1	[P08588]	METABOLITE	0.105016252
A03FA01	metoclopramide	C0004096	asthma	1	[P11229]	DRUG	0.33290977
A03FA01	metoclopramide	C0004093	asthenia	1	[P28223]	DRUG	0.043339606
C07AG02	carvedilol	C0004093	asthenia	1	[P31645]	DRUG_AND_METABOLITE	0.037934867
C07AG02	carvedilol	C0004096	asthma	5	[P07550, P15692, P47989, P19320, P23219]	DRUG	0.003335247
L02BG03	anastrozole	C0029456	osteoporosis	2	[P11511, P08684]	DRUG_AND_METABOLITE	0.010207101
R03DC03	montelukast	C0042109	urticaria	1	[P09917]	DRUG_AND_METABOLITE	0.029823411
N04BX01	tolcapone	C0041912	upper respiratory tract infection	1	[P27487]	METABOLITE	0.30867782
J04AC01	isoniazid	C0027813	neuritis	1	[P14780]	METABOLITE	0.062319473
L02BA01	tamoxifen	C0015672	fatigue	1	[P35354]	DRUG	0.052406311
N05AE04	ziprasidone	C0037763	spasm	2	[P14867, P21918]	DRUG	0.010694063
C09AA06	quinapril	C0038454	cerebrovascular accident	1	[P12821]	DRUG_AND_METABOLITE	0.047753035
L02BA01	tamoxifen	C0015695	liver fatty	1	[P05181]	DRUG	0.120580095
N02CC03	zolmitriptan	C0007097	carcinoma	1	[P05177]	DRUG	0.489522162
J05AF03	zalcitabine	C0001339	acute pancreatitis	1	[Q00613]	DRUG	0.168674498
A10BB09	gliclazide	C0015230	rash	1	[P15692]	DRUG	0.069716619
A07EA06	budesonide	C0030193	pain	1	[P11511]	METABOLITE	0.040283843
N05AH02	clozapine	C0018801	heart failure	3	[Q9Y2I1, Q12809, P07550]	DRUG_AND_METABOLITE	0.03417318
N06AA06	trimipramine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.014245386
N01AH01	fentanyl	C0020538	hypertension	2	[P20815, P28223]	DRUG	0.083451338
N03AF02	oxcarbazepine	C0004134	ataxia	1	[P35498]	DRUG	0.044582135
L04AX04	lenalidomide	C0009812	constitutional symptoms	1	[P01375]	DRUG	0.019239124
N02CC01	sumatriptan	C0034065	pulmonary embolism	1	[P02768]	METABOLITE	0.060203322
N06BA04	methylphenidate	C0004998	skin benign neoplasm	1	[P23975]	DRUG_AND_METABOLITE	0.499995859
J01MA01	ofloxacin	C0151826	chest pain substernal	1	[P02768]	METABOLITE	0.01564125
M01AE09	flurbiprofen	C0019080	hemorrhage	1	[P11712]	DRUG	0.083451338
N06BA07	modafinil	C0024115	lung disorder	1	[P05177]	DRUG	0.163544848
C01BC03	propafenone	C0023211	left bundle branch block	1	[Q14524]	DRUG	0.005809415
A07EC01	sulfasalazine	C0027726	nephrotic syndrome	3	[P37231, P35354, P09211]	DRUG	0.030279561
C09AA09	fosinopril	C0042109	urticaria	1	[P12821]	DRUG	0.015087595
A07EC01	sulfasalazine	C0027720	nephrosis	1	[P09211]	DRUG	0.117247144
N05AX12	aripiprazole	C0013384	dyskinesia	4	[P05129, P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.001465281
C10AB04	gemfibrozil	C0009443	common cold	2	[P37231, Q07869]	DRUG	0.097707759
J05AE01	saquinavir	C0020443	hypercholesterolemia	1	[Q9Y6L6]	DRUG	0.07443691
N06BA01	amphetamine	C0878544	cardiomyopathy	3	[O76082, P08588, P14780]	METABOLITE	0.062319473
N04BC05	pramipexole	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG	1.54047E-05
J01FA09	clarithromycin	C0004096	asthma	2	[P00813, P33527]	DRUG	0.082415968
N04BC05	pramipexole	C0699744	ear infection	1	[P07550]	DRUG	0.481982093
N03AF01	carbamazepine	C0018524	hallucinations	5	[P08183, P35498, Q99250, P04156, Q9NY46]	DRUG	2.63993E-05
J05AE01	saquinavir	C0020433	bilirubinemia	3	[Q92887, P21439, Q9Y6L6]	DRUG	0.000109967
N05BC01	meprobamate	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.241817843
N06BA01	amphetamine	C0027051	myocardial infarction	10	[P14780, P21554, P00325, P07550, P11712, P33261, P31645, P05177, P08588, P18089]	METABOLITE	0.013399503
C07AA06	timolol	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.02266211
N04BC05	pramipexole	C0699790	colon cancer	3	[Q9H3N8, P25021, P35367]	DRUG	0.297033064
N06AA01	desipramine	C0033975	psychosis	7	[P35462, P28223, P21917, Q13639, P28222, P31645, P08908]	DRUG	1.54047E-05
L01XE01	imatinib	C0017168	gastroesophageal reflux	3	[P33261, Q02750, P36507]	DRUG	0.036771335
L01XE01	imatinib	C0017152	gastritis	1	[P23219]	DRUG	0.404303778
M01AH03	valdecoxib	C0025202	melanoma	2	[P25021, P35354]	DRUG_AND_METABOLITE	0.468493835
L04AX02	thalidomide	C0030305	pancreatitis	5	[P01375, Q99895, P05181, P04798, P35354]	DRUG_AND_METABOLITE	0.017596968
M01AB02	sulindac	C0008325	cholecystitis	1	[P37231]	DRUG_AND_METABOLITE	0.046530938
M01AH02	rofecoxib	C0017152	gastritis	3	[P03973, P23219, P35354]	DRUG_AND_METABOLITE	0.005396749
P01BA01	chloroquine	C0002874	aplastic anemia	2	[P01375, P04798]	DRUG	0.022150412
N06AX16	venlafaxine	C0018790	cardiac arrest	4	[Q14524, Q13936, P18089, P07550]	DRUG	0.000495529
N06AX16	venlafaxine	C0018799	heart disease	8	[P31645, P08588, Q14524, P11712, P07550, P20813, Q13639, P41595]	DRUG	0.005814835
N05AH02	clozapine	C0013146	abuse	1	[P41595]	DRUG_AND_METABOLITE	0.048676004
M03BX08	cyclobenzaprine	C0027051	myocardial infarction	13	[P02768, P21554, P13945, P05362, P06276, P07550, P11712, P33261, P31645, P23219, P05177, P08588, P18089]	DRUG_AND_METABOLITE	0.000790318
N05BA01	diazepam	C0026650	movement disorders	2	[P35498, P14416]	DRUG	0.020334532
L01BA01	methotrexate	C0019158	hepatitis	1	[P02768]	DRUG	0.131823028
N05AA01	chlorpromazine	C0036572	seizures	3	[O43526, Q99250, P35498]	DRUG_AND_METABOLITE	0.016288574
N03AX12	gabapentin	C0013384	dyskinesia	1	[Q9NY47]	DRUG_AND_METABOLITE	0.050141944
J05AF03	zalcitabine	C0030305	pancreatitis	1	[Q00613]	DRUG	0.168674498
L02BG06	exemestane	C0024236	lymphedema	1	[P08684]	DRUG	0.012792437
M01AE01	ibuprofen	C0024141	lupus	2	[P10145, P33527]	DRUG	0.341499931
N06AA09	amitriptyline	C0878544	cardiomyopathy	3	[O76082, Q12809, P08588]	DRUG_AND_METABOLITE	0.082623154
C01BA03	disopyramide	C0018790	cardiac arrest	2	[Q14524, Q12809]	DRUG	0.002250291
B01AC05	ticlopidine	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.032885129
C08CA02	felodipine	C0027051	myocardial infarction	6	[P03372, P06276, P10275, P03951, P04150, P11712]	DRUG	0.006419523
N03AX16	pregabalin	C0009421	coma	1	[O00555]	DRUG	0.004163713
N05AX08	risperidone	C0001430	adenomas	2	[Q12809, P32239]	DRUG_AND_METABOLITE	0.28039678
N05AH02	clozapine	C0001339	acute pancreatitis	2	[P05181, P04798]	DRUG	0.152131121
C09CA06	candesartan	C0010054	coronary artery disease	1	[P30556]	DRUG_AND_METABOLITE	0.126293414
R01AD01	beclomethasone	C0235761	nasal septum perforation	4	[P35354, P04083, P07148, P35228]	DRUG_AND_METABOLITE	0.005600162
A03BA01	atropine	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG_AND_METABOLITE	0.000282761
C08DB01	diltiazem	C0019080	hemorrhage	1	[P11712]	DRUG	0.085289777
N06AX16	venlafaxine	C0023890	cirrhosis	3	[P34972, P08684, P21554]	METABOLITE	0.101857725
C09AA05	ramipril	C0007820	cerebrovascular disorder	1	[P12821]	DRUG	0.054359067
L01BC06	capecitabine	C0018944	hematoma	1	[P11712]	DRUG_AND_METABOLITE	0.076200799
N03AF01	carbamazepine	C0039231	tachycardia	1	[Q14524]	DRUG	0.035695087
C09CA06	candesartan	C0022658	nephropathy	2	[P30556, P23219]	DRUG_AND_METABOLITE	0.008056217
N06AB06	sertraline	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.027718977
A10BB03	tolbutamide	C0020615	hypoglycemia	2	[P09467, Q09428]	DRUG	0.006209192
C10AA05	atorvastatin	C0003864	arthritis	1	[P27487]	DRUG_AND_METABOLITE	0.114588485
N06AX16	venlafaxine	C1527304	allergic reaction	5	[P41595, Q01959, P29475, P35367, P25021]	DRUG_AND_METABOLITE	0.000196394
N03AB02	phenytoin	C0024141	lupus	1	[Q92887]	DRUG	0.364854773
N06AA06	trimipramine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.142528506
N06AX21	duloxetine	C0020615	hypoglycemia	2	[P07550, P30874]	DRUG	0.0576214
N02CC06	eletriptan	C0027051	myocardial infarction	3	[P11712, P33261, P23219]	DRUG	0.023218364
N02AA01	morphine	C0152128	drug withdrawal	1	[P14416]	DRUG_AND_METABOLITE	0.018505915
C07AA07	sotalol	C0021311	infection	1	[P07550]	DRUG	0.297472422
L04AA06	mycophenolic acid	C0013295	duodenal ulcer	1	[P37231]	DRUG_AND_METABOLITE	0.021227014
M01AC06	meloxicam	C0019158	hepatitis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.005127252
N02AA03	hydromorphone	C0013384	dyskinesia	5	[P35498, P14416, P21917, P35462, P21964]	DRUG_AND_METABOLITE	2.06199E-05
N02AA03	hydromorphone	C0013395	Dyspepsia	2	[P23219, P21964]	DRUG_AND_METABOLITE	0.00215595
N02AE01	buprenorphine	C0004093	asthenia	1	[P31645]	DRUG	0.037086334
J01MA01	ofloxacin	C0149931	migraine	1	[P08684]	DRUG	0.07026785
G03XC01	raloxifene	C0476089	endometrial cancer	4	[P03372, P11511, P08684, Q92731]	DRUG	0.002346816
J01MA01	ofloxacin	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.036928011
M03BX08	cyclobenzaprine	C0004134	ataxia	1	[P35498]	DRUG_AND_METABOLITE	0.216303482
J01FA10	azithromycin	C0006266	bronchospasm	2	[P00813, P33527]	DRUG_AND_METABOLITE	0.092998912
C07AG02	carvedilol	C0015672	fatigue	1	[P31645]	DRUG_AND_METABOLITE	0.037934867
G04CA02	tamsulosin	C0015230	rash	1	[P08908]	DRUG	0.199588919
N05CF01	zopiclone	C0019158	hepatitis	2	[P05181, P23219]	DRUG	0.018096702
N05AH03	olanzapine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	5.17627E-07
N06AA04	clomipramine	C0042024	urinary incontinence	4	[P08172, P28223, P21917, P29475]	METABOLITE	0.000366068
N06AB08	fluvoxamine	C0003123	anorexia	5	[P28223, P28335, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.77828E-06
N03AG06	tiagabine	C0149931	migraine	1	[P08684]	DRUG	0.095416353
L04AX02	thalidomide	C0026821	muscle cramps	1	[Q08499]	DRUG	0.058400414
N05AC02	thioridazine	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG	8.41518E-05
A05AA02	ursodeoxycholic acid	C0042029	urinary tract infection	1	[P11473]	METABOLITE	0.030183251
N02CA01	dihydroergotamine	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.054359067
C01BC04	flecainide	C0042510	ventricular fibrillation	1	[Q14524]	DRUG	0.007694241
G03DA04	progesterone	C0036572	seizures	1	[P50993]	METABOLITE	0.147655305
C07AB07	bisoprolol	C0011603	dermatitis	1	[P07550]	DRUG_AND_METABOLITE	0.089912296
M01AH01	celecoxib	C0012813	diverticulitis	1	[P31645]	DRUG	0.092389278
J01DB04	cefazolin	C0019158	hepatitis	1	[P02768]	DRUG	0.063596471
N06AA04	clomipramine	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.046166301
L01XX35	anagrelide	C0042024	urinary incontinence	1	[P28223]	METABOLITE	0.030530396
J01MA01	ofloxacin	C0442874	neuropathy	1	[P08183]	DRUG	0.090057814
L04AX02	thalidomide	C0030196	Pain in limb	1	[Q08499]	DRUG	0.04898487
C08DA01	verapamil	C0018681	headache	1	[O00555]	DRUG	0.077924197
C03AA04	chlorothiazide	C0030552	weakness	1	[P55017]	DRUG	0.010207101
N02AA01	morphine	C0152032	urinary hesitancy	1	[P23219]	DRUG	0.17352585
B01AC07	dipyridamole	C0011603	dermatitis	1	[Q07343]	DRUG	0.222877858
N01BB09	ropivacaine	C0039231	tachycardia	1	[Q14524]	METABOLITE	0.035695087
N03AF01	carbamazepine	C0018801	heart failure	1	[Q14524]	DRUG	0.128451012
N03AF01	carbamazepine	C0018802	congestive heart failure	1	[Q14524]	DRUG	0.128451012
N06AX16	venlafaxine	C0018944	hematoma	1	[P11712]	DRUG	0.158485579
M01AC06	meloxicam	C0019080	hemorrhage	1	[P11712]	DRUG	0.039903358
G03BA03	testosterone	C0019080	hemorrhage	1	[P11712]	METABOLITE	0.179584572
M03BX08	cyclobenzaprine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.015956935
N05AH02	clozapine	C0018524	hallucinations	2	[P08183, P36544]	DRUG	0.088373721
L04AX02	thalidomide	C0022408	arthrosis	2	[P19838, P01375]	DRUG	0.209546795
M03BX01	baclofen	C0575081	abnormal gait	1	[P35498]	DRUG	0.037934867
N02BA11	diflunisal	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.000772249
N05AX12	aripiprazole	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.060823811
N02CC01	sumatriptan	C0004096	asthma	2	[P07550, O94956]	METABOLITE	0.27121873
C01BA02	procainamide	C0015230	rash	1	[P26358]	DRUG	0.153852185
N03AF01	carbamazepine	C0018790	cardiac arrest	1	[Q14524]	DRUG	0.068205178
N06AA04	clomipramine	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.159051487
A02BC02	pantoprazole	C0024115	lung disorder	3	[P08183, P04798, P05177]	DRUG_AND_METABOLITE	0.038391534
N06DA03	rivastigmine	C0033975	psychosis	2	[P21397, P31645]	DRUG	0.003335247
N05AH04	quetiapine	C0037763	spasm	2	[P14867, P21918]	DRUG	0.010512491
N05AG02	pimozide	C0015230	rash	5	[P07550, P21731, P28223, P08908, P31645]	DRUG	0.023991569
J05AE01	saquinavir	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.096910793
N06BA09	atomoxetine	C0003123	anorexia	7	[P28223, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG	3.59294E-07
M01AH02	rofecoxib	C0030305	pancreatitis	1	[P35354]	DRUG_AND_METABOLITE	0.240619988
N05AX12	aripiprazole	C0021311	infection	2	[P07550, P17252]	DRUG_AND_METABOLITE	0.482581952
N05BB01	hydroxyzine	C0009951	convulsions	3	[P35498, Q99250, Q9NY46]	DRUG	0.004927408
A02BB01	misoprostol	C0041912	upper respiratory tract infection	1	[Q07869]	METABOLITE	0.295414647
N06AB08	fluvoxamine	C0030305	pancreatitis	2	[P05181, P04798]	DRUG_AND_METABOLITE	0.03423754
N05CF02	zolpidem	C0018799	heart disease	2	[P23219, P11712]	DRUG	0.098858767
A10BB09	gliclazide	C0032285	pneumonia	1	[P15692]	DRUG	0.040601904
C09AA03	lisinopril	C0038454	cerebrovascular accident	1	[P12821]	DRUG	0.05696568
C08CA05	nifedipine	C0012833	dizziness	1	[P29274]	DRUG	0.029545951
S01ED02	betaxolol	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.043989678
A02BC04	rabeprazole	C0013395	Dyspepsia	1	[P23219]	DRUG	0.047761265
G04BE07	apomorphine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000125975
A02BC04	rabeprazole	C0013390	dysmenorrhea	2	[P35354, P04798]	DRUG_AND_METABOLITE	0.000782153
C01BB02	mexiletine	C0009806	constipation	4	[Q14524, P46098, P41595, P31645]	DRUG_AND_METABOLITE	1.43265E-05
N06AA06	trimipramine	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.128073342
N02CC03	zolmitriptan	C0003123	anorexia	3	[P21397, P28221, P14416]	DRUG	0.00016516
L01CB01	etoposide	C0035078	renal failure	1	[P08183]	DRUG_AND_METABOLITE	0.09230254
D08AC02	chlorhexidine	C0002792	anaphylaxis	1	[P08253]	DRUG	0.029738649
N05AB02	fluphenazine	C0038454	cerebrovascular accident	1	[P28223]	DRUG_AND_METABOLITE	0.266756319
N06AB06	sertraline	C0033975	psychosis	4	[P28223, P21397, P31645, P08908]	DRUG_AND_METABOLITE	0.0005807
C10AA04	fluvastatin	C0011603	dermatitis	3	[P37231, P21731, Q07869]	METABOLITE	0.012792437
N06AB03	fluoxetine	C0019158	hepatitis	1	[P05181]	DRUG	0.180499559
C07AA03	pindolol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.111855571
C07AA03	pindolol	C0018801	heart failure	1	[P07550]	DRUG	0.111855571
L01CB01	etoposide	C0011603	dermatitis	2	[P42574, O95255]	DRUG_AND_METABOLITE	0.077843187
M01AH02	rofecoxib	C0020517	hypersensitivity	3	[P41595, Q01959, P25021]	DRUG_AND_METABOLITE	0.008125369
N06DA02	donepezil	C0042024	urinary incontinence	2	[P28223, P21917]	DRUG	0.000999872
M01AH02	rofecoxib	C0020538	hypertension	10	[P15502, P35348, P21728, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089]	DRUG_AND_METABOLITE	8.65131E-05
L04AX02	thalidomide	C0038454	cerebrovascular accident	4	[Q08499, P01375, P35354, P00488]	METABOLITE	0.088298651
C09AA08	cilazapril	C0001824	agranulocytosis	1	[P08183]	DRUG	0.019687894
N06AX21	duloxetine	C0020473	hyperlipidemia	2	[P23219, P07550]	DRUG	0.130771077
A07EA06	budesonide	C0042109	urticaria	1	[P09917]	METABOLITE	0.073076437
N06AX21	duloxetine	C0020456	hyperglycemia	1	[P35354]	METABOLITE	0.262768459
G03HA01	cyproterone	C0042133	uterine fibroids	2	[P11511, P10275]	DRUG	0.001734415
N05AH03	olanzapine	C0020538	hypertension	10	[P35348, P13945, P07550, P21728, P31645, P28223, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	0.000384154
N02CC01	sumatriptan	C0004153	atherosclerotic vascular disease	5	[P08684, P03372, Q92731, P11712, P02768]	METABOLITE	0.025573425
A02BC04	rabeprazole	C0151826	chest pain substernal	1	[P02768]	DRUG_AND_METABOLITE	0.028343005
C09AA02	enalapril	C0004238	atrial fibrillation	1	[P12821]	DRUG_AND_METABOLITE	0.05753837
A10BA02	metformin	C0021311	infection	1	[P27487]	DRUG	0.180184941
N04BC05	pramipexole	C0037763	spasm	1	[P21918]	DRUG	0.058261047
L01CB01	etoposide	C0023530	leukopenia	2	[Q92887, P08183]	DRUG_AND_METABOLITE	0.007713391
N07XX02	riluzole	C0009421	coma	1	[O00555]	DRUG	0.006405429
A02BC04	rabeprazole	C0013404	dyspnea	1	[P47712]	METABOLITE	0.084103037
G03CA03	estradiol	C0014130	Endocrine Disorders	5	[Q16678, P32239, P50225, P04798, P03372]	DRUG_AND_METABOLITE	0.053993679
L04AX04	lenalidomide	C0149801	urosepsis	1	[P01375]	DRUG	0.117444075
C09AA03	lisinopril	C0011849	diabetes mellitus	1	[P12821]	DRUG	0.092356341
L01BB02	mercaptopurine	C0010709	cyst	2	[P47989, O15440]	DRUG	0.326035936
C03AA04	chlorothiazide	C0030305	pancreatitis	1	[P00918]	DRUG	0.051696381
N03AG01	valproic acid	C0001824	agranulocytosis	1	[O60656]	DRUG	0.093159412
N04BD01	selegiline	C0024299	lymphoma	1	[P08183]	DRUG	0.386521894
S01AA14	penicillin G	C0004096	asthma	3	[P12319, P16050, O94956]	DRUG	0.160248208
N03AG01	valproic acid	C0018944	hematoma	1	[P11712]	DRUG	0.105895855
C01BA03	disopyramide	C0018802	congestive heart failure	2	[Q14524, Q12809]	DRUG	0.009779478
L04AX02	thalidomide	C0022660	acute renal failure	1	[P01375]	DRUG	0.136228492
N06AA12	doxepin	C0036572	seizures	3	[O43526, Q99250, P35498]	DRUG_AND_METABOLITE	0.010836935
C09CA06	candesartan	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.016701405
N04BC02	pergolide	C0011849	diabetes mellitus	3	[P08684, P18089, P07550]	DRUG	0.060597648
H02AB02	dexamethasone	C0027051	myocardial infarction	8	[P35354, P04798, P10275, P04150, P03956, P11712, P33261, P23219]	DRUG_AND_METABOLITE	0.000673189
M03BX08	cyclobenzaprine	C0041912	upper respiratory tract infection	6	[P05107, P07550, P04156, Q13936, P05362, P23219]	METABOLITE	0.344606355
N06AB03	fluoxetine	C0019080	hemorrhage	1	[P11712]	DRUG	0.123348216
R03AC12	salmeterol	C0021311	infection	1	[P07550]	DRUG	0.225075103
A03FA02	cisapride	C0015672	fatigue	1	[P28223]	DRUG	0.050948197
C07AA06	timolol	C0013604	edema	1	[P08588]	DRUG	0.021299045
D07AC04	fluocinolone acetonide	C0021311	infection	1	[P04150]	DRUG	0.127583335
N04BC04	ropinirole	C0699744	ear infection	1	[P07550]	DRUG	0.441061321
G04CA02	tamsulosin	C0015672	fatigue	1	[P35354]	METABOLITE	0.039002635
N07XX02	riluzole	C0025637	methemoglobinemia	1	[P05177]	DRUG	0.01690995
A07EA06	budesonide	C0152029	sinus congestion	1	[P35228]	METABOLITE	0.163029107
N05AH04	quetiapine	C0013595	eczema	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG	0.002642872
L01BC06	capecitabine	C0002871	anemia	1	[P02768]	METABOLITE	0.105422145
C01BB02	mexiletine	C0009951	convulsions	8	[Q07699, P35498, Q9UBS5, P36544, Q99250, Q13255, P08908, P31645]	DRUG_AND_METABOLITE	0.00017745
C09AA10	trandolapril	C0018799	heart disease	1	[P12821]	DRUG_AND_METABOLITE	0.080618312
N02AA03	hydromorphone	C0151950	deep thrombophlebitis	1	[P21964]	DRUG_AND_METABOLITE	0.124559086
N02AA01	morphine	C0020538	hypertension	7	[P20815, P35348, P21728, P31645, P11712, P23975, P21964]	DRUG_AND_METABOLITE	0.000948536
L01BA01	methotrexate	C0497327	dementia	1	[P42898]	DRUG	0.269544342
A02BC01	omeprazole	C0030305	pancreatitis	2	[Q99895, P04798]	DRUG_AND_METABOLITE	0.047322811
C09AA07	benazepril	C0013404	dyspnea	1	[P12821]	DRUG_AND_METABOLITE	0.017596968
N05AG02	pimozide	C0002874	aplastic anemia	1	[P04798]	DRUG	0.284120681
N03AF01	carbamazepine	C0027813	neuritis	1	[P08183]	DRUG	0.083226631
A02BC04	rabeprazole	C0001824	agranulocytosis	1	[P08183]	METABOLITE	0.09523719
N05AH02	clozapine	C0013595	eczema	5	[P07550, P21731, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.021841092
N05AH04	quetiapine	C0013604	edema	1	[P08588]	DRUG	0.062610213
N03AG01	valproic acid	C0010709	cyst	11	[P05177, P11509, P13726, Q8WUI4, P20815, P53985, Q92769, Q13547, Q9UBN7, P56524, P14550]	DRUG	0.083908823
M01AE02	naproxen	C0013395	Dyspepsia	1	[P23219]	DRUG	0.056713506
N06AB03	fluoxetine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.48976E-07
N06AA12	doxepin	C0686347	tardive dyskinesia	1	[P35498]	DRUG_AND_METABOLITE	0.107981436
D08AC02	chlorhexidine	C0041912	upper respiratory tract infection	2	[P14780, P08253]	DRUG	0.062423964
N05AH03	olanzapine	C0020615	hypoglycemia	1	[P07550]	DRUG_AND_METABOLITE	0.134277285
N06AX21	duloxetine	C0020517	hypersensitivity	7	[P41595, Q8NER1, Q01959, P29475, P35367, P25021, Q9H3N8]	DRUG	3.52831E-05
J01XX08	linezolid	C0003123	anorexia	1	[P21397]	DRUG	0.065940698
G03CA03	estradiol	C0041912	upper respiratory tract infection	1	[P03372]	DRUG_AND_METABOLITE	0.499995859
M01AB15	ketorolac	C0002871	anemia	3	[P10145, P02768, P07148]	DRUG	0.000832892
P01BA01	chloroquine	C0018681	headache	1	[P01375]	DRUG	0.040753047
D01AE15	terbinafine	C0030193	pain	1	[P11511]	DRUG	0.023338897
R06AD02	promethazine	C0018524	hallucinations	5	[P08183, P35498, Q99250, P04156, Q9NY46]	DRUG	0.000126221
N06AA17	amoxapine	C0039231	tachycardia	2	[P07550, P08588]	METABOLITE	0.00363511
N03AX09	lamotrigine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.044574807
L04AX04	lenalidomide	C0011570	mental depression	1	[P33261]	DRUG	0.075667737
A03FA01	metoclopramide	C1527304	allergic reaction	2	[P41595, P35367]	DRUG	0.013782573
R03DC03	montelukast	C0011603	dermatitis	1	[Q9Y271]	DRUG_AND_METABOLITE	0.130090252
B01AC07	dipyridamole	C0006266	bronchospasm	2	[P00813, Q08499]	DRUG	0.098169818
N06AB08	fluvoxamine	C0042514	ventricular tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.030408848
J05AF04	stavudine	C0231528	myalgia	1	[O00142]	DRUG	0.115394253
N05AB03	perphenazine	C0013595	eczema	3	[P28223, P08908, P31645]	METABOLITE	0.028326723
N02CC01	sumatriptan	C0009806	constipation	3	[A5X5Y0, P46098, P41595]	DRUG	0.000162559
C01BB01	lidocaine	C0428977	bradycardia	1	[Q14524]	DRUG	0.022517376
C07AG02	carvedilol	C0004238	atrial fibrillation	2	[P16860, Q14524]	DRUG	0.016368485
N06AX16	venlafaxine	C0041948	uremia	2	[P35348, P35368]	DRUG	0.179056381
N06AA01	desipramine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000424818
M01AH01	celecoxib	C0001339	acute pancreatitis	2	[P00918, P35354]	DRUG_AND_METABOLITE	0.100012956
R03DC03	montelukast	C0011615	atopic dermatitis	1	[Q9Y271]	DRUG_AND_METABOLITE	0.100741343
J01AA08	minocycline	C0027059	myocarditis	2	[P08253, P14780]	DRUG	0.028561234
M01AB05	diclofenac	C0020538	hypertension	7	[P35348, P21728, Q9Y2I1, P28223, P11712, P08913, P18089]	DRUG	0.010781267
C10AB04	gemfibrozil	C0009319	colitis	1	[P37231]	DRUG	0.112133252
N04BC04	ropinirole	C0699885	bladder carcinoma	1	[P05177]	DRUG	0.299331173
J01MA01	ofloxacin	C0151798	hepatic necrosis	2	[Q92887, P08684]	DRUG	0.028105805
N03AX09	lamotrigine	C0013384	dyskinesia	1	[P35498]	DRUG	0.064336245
N07BC02	methadone	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
V03AF03	leucovorin	C0007097	carcinoma	3	[P04818, Q92887, O15438]	DRUG	0.288172984
C10AA01	simvastatin	C0022346	jaundice	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.017783546
L01XE03	erlotinib	C0151908	dry skin	1	[Q9UKE5]	DRUG_AND_METABOLITE	0.479535142
S01ED03	levobunolol	C0038454	cerebrovascular accident	1	[P07550]	DRUG	0.074184599
C09AA13	moexipril	C0027051	myocardial infarction	1	[P12821]	DRUG_AND_METABOLITE	0.117247144
J05AE03	ritonavir	C0011849	diabetes mellitus	3	[P11712, P08684, P10632]	DRUG	0.033688131
N06AX16	venlafaxine	C0041912	upper respiratory tract infection	3	[P07550, Q13936, P17252]	DRUG	0.471392998
C09AA02	enalapril	C0004096	asthma	1	[P12821]	DRUG_AND_METABOLITE	0.179324562
M01AB05	diclofenac	C0020456	hyperglycemia	3	[P35354, P10145, P07148]	DRUG	0.012596519
C09AA02	enalapril	C0004093	asthenia	1	[P12821]	DRUG_AND_METABOLITE	0.023218364
N07BA01	nicotine	C0013390	dysmenorrhea	1	[P04798]	DRUG	0.028111074
N03AG01	valproic acid	C0001430	adenomas	1	[P23219]	DRUG	0.371171569
A02BC01	omeprazole	C1527304	allergic reaction	2	[Q8NER1, P25021]	DRUG_AND_METABOLITE	0.014941206
C09AA02	enalapril	C0041912	upper respiratory tract infection	1	[Q9BYF1]	DRUG_AND_METABOLITE	0.28077306
C07AG02	carvedilol	C0015230	rash	4	[P07550, P08908, P15692, P31645]	DRUG_AND_METABOLITE	0.00260623
J01BA01	chloramphenicol	C0002874	aplastic anemia	1	[P08174]	DRUG_AND_METABOLITE	0.074465973
J05AE03	ritonavir	C0023467	AML	4	[Q9UNQ0, P08183, P33527, P05177]	DRUG	0.00772744
G03BA02	methyltestosterone	C0018418	gynecomastia	1	[P11511]	DRUG_AND_METABOLITE	0.032885129
L04AX04	lenalidomide	C0011615	atopic dermatitis	1	[P01375]	DRUG	0.171578823
N01BB01	bupivacaine	C0018790	cardiac arrest	3	[Q14524, Q12809, Q13936]	METABOLITE	0.000774385
D10AA02	methylprednisolone	C0020538	hypertension	2	[P08235, P04150]	DRUG_AND_METABOLITE	0.028748417
S01ED04	metipranolol	C0020538	hypertension	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.008758372
C09AA03	lisinopril	C0034063	pulmonary edema	1	[P12821]	DRUG	0.007694241
N04BC05	pramipexole	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.00486818
N03AG06	tiagabine	C0085584	encephalopathy	3	[P14867, P18505, P18507]	DRUG	0.002812013
R03AC13	formoterol	C0027651	tumor	4	[P11509, P33261, P07550, P13945]	DRUG	0.13772507
C07AB07	bisoprolol	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.012425662
N05AH02	clozapine	C0017601	glaucoma	1	[Q16678]	DRUG	0.174370945
C08CA04	nicardipine	C0021311	infection	1	[Q13936]	DRUG	0.475758467
C01BD01	amiodarone	C0001824	agranulocytosis	1	[P08183]	DRUG	0.062641595
L04AA06	mycophenolic acid	C0025202	melanoma	1	[P37231]	DRUG_AND_METABOLITE	0.179776721
M01AH01	celecoxib	C0001430	adenomas	3	[P18054, P35354, P23219]	DRUG_AND_METABOLITE	0.131948393
J05AE01	saquinavir	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.047831182
A07EC01	sulfasalazine	C0027947	neutropenia	1	[Q92887]	DRUG	0.070518569
N05AH03	olanzapine	C0020473	hyperlipidemia	1	[P07550]	DRUG_AND_METABOLITE	0.219693462
A10BB09	gliclazide	C0003860	arteritis	1	[P15692]	DRUG	0.021841092
A10BB09	gliclazide	C0003864	arthritis	1	[P15692]	DRUG	0.051010353
G03CA03	estradiol	C0014175	endometriosis	6	[P03372, Q92731, P14061, P08842, P56937, P04798]	DRUG_AND_METABOLITE	0.021747559
C09AA13	moexipril	C0015672	fatigue	1	[P12821]	DRUG_AND_METABOLITE	0.014253709
N02CC01	sumatriptan	C0009951	convulsions	2	[P08183, P08908]	DRUG	0.123730513
N02CC06	eletriptan	C0017152	gastritis	1	[P23219]	DRUG	0.057691049
N06AB03	fluoxetine	C0007859	neck pain	1	[Q08499]	METABOLITE	0.035667691
N04BC04	ropinirole	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.439527473
L01AA01	cyclophosphamide	C0009319	colitis	1	[P08183]	DRUG	0.140240596
J01AA07	tetracycline	C0014356	enterocolitis	1	[P08254]	DRUG_AND_METABOLITE	0.057987175
N06AX16	venlafaxine	C0023530	leukopenia	1	[P08183]	DRUG	0.166846606
N04BC04	ropinirole	C0041948	uremia	3	[P35348, P35368, P25100]	DRUG	0.013081633
N04BC04	ropinirole	C0027051	myocardial infarction	4	[P07550, P05177, P08588, P18089]	DRUG	0.031289625
C03CA01	furosemide	C0001824	agranulocytosis	1	[Q92887]	DRUG	0.06555312
L01CB01	etoposide	C0011991	diarrhea	1	[Q92887]	DRUG_AND_METABOLITE	0.042804682
M01AE02	naproxen	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG	0.071241753
N05AH02	clozapine	C0013390	dysmenorrhea	1	[P04798]	DRUG	0.040636881
N05AX08	risperidone	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.005292839
N07BC02	methadone	C0037763	spasm	2	[P14867, P21918]	METABOLITE	0.010316539
G04CA03	terazosin	C0015230	rash	2	[P28223, P08908]	DRUG_AND_METABOLITE	0.119473327
J05AE03	ritonavir	C0011991	diarrhea	1	[Q92887]	DRUG	0.041509351
N05AB03	perphenazine	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.003144473
C07AA05	propranolol	C0020517	hypersensitivity	2	[P41595, P35367]	DRUG	0.028343005
L04AX02	thalidomide	C0006277	bronchitis	1	[P01375]	DRUG	0.084103037
C07AB02	metoprolol	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.024401265
N06AA04	clomipramine	C0042514	ventricular tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.086098006
J05AE03	ritonavir	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.007178498
N06AA09	amitriptyline	C0023530	leukopenia	2	[Q07817, P08183]	DRUG_AND_METABOLITE	0.066475501
L01XX05	hydroxyurea	C0021311	infection	1	[P14780]	METABOLITE	0.225075103
S01ED02	betaxolol	C0021311	infection	2	[P07550, Q13936]	METABOLITE	0.196351844
N04AC01	benztropine	C0033975	psychosis	5	[P35462, P28223, P21917, P31645, P08908]	DRUG_AND_METABOLITE	1.48822E-05
N03AX11	topiramate	C0575081	abnormal gait	1	[P35498]	DRUG	0.034147949
N03AB04	mephenytoin	C0004134	ataxia	1	[P35498]	DRUG_AND_METABOLITE	0.125551671
C02CA04	doxazosin	C0151744	myocardial ischemia	1	[Q12809]	DRUG	0.080832299
A02BA02	ranitidine	C0009806	constipation	1	[P46098]	DRUG	0.027706733
N04BD01	selegiline	C0010709	cyst	7	[P05177, P11509, P08183, P05181, Q05940, P23975, P07477]	METABOLITE	0.282129303
N04BD01	selegiline	C0151744	myocardial ischemia	1	[P08588]	METABOLITE	0.128451012
L04AX04	lenalidomide	C0149931	migraine	1	[P01375]	DRUG	0.072738991
N06AX16	venlafaxine	C0003123	anorexia	8	[P28223, P28335, P21397, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.48976E-07
N06DA03	rivastigmine	C0038363	ulcerative stomatitis	1	[P31645]	DRUG	0.00976001
N03AB02	phenytoin	C0018790	cardiac arrest	2	[Q14524, Q12809]	DRUG	0.014025764
G03XC01	raloxifene	C0699885	bladder carcinoma	2	[Q92731, P03372]	DRUG	0.068147063
A02BC01	omeprazole	C0267112	gastritis hemorrhagic	1	[P20648]	DRUG_AND_METABOLITE	0.088782147
A10BG02	rosiglitazone	C0018801	heart failure	1	[P37231]	DRUG_AND_METABOLITE	0.091392995
A10BG02	rosiglitazone	C0018802	congestive heart failure	1	[P37231]	DRUG_AND_METABOLITE	0.091392995
C08CA02	felodipine	C0004093	asthenia	1	[P04150]	DRUG	0.048595777
D07AC03	desoximetasone	C0021311	infection	1	[P04150]	DRUG	0.063071299
L04AX02	thalidomide	C0021311	infection	4	[P01375, P19838, P35354, P23219]	DRUG_AND_METABOLITE	0.493688912
L02AB01	megestrol	C0442874	neuropathy	1	[P08183]	DRUG	0.051686979
N05AD01	haloperidol	C0013384	dyskinesia	4	[P35498, P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.003377799
J05AE04	nelfinavir	C0231528	myalgia	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.082956716
N06AB05	paroxetine	C0013384	dyskinesia	1	[P14416]	DRUG	0.114588485
N04BC05	pramipexole	C0013595	eczema	4	[P07550, P28223, P08908, P31645]	DRUG	0.011557989
J05AF03	zalcitabine	C0004134	ataxia	1	[P54098]	METABOLITE	0.097296676
N06AX21	duloxetine	C0022104	irritable bowel syndrome	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.009521978
C07AA05	propranolol	C0011570	mental depression	9	[P33261, P08684, P28223, P28335, P28222, P50406, P47898, P08908, P31645]	DRUG	0
C02AC01	clonidine	C0428977	bradycardia	1	[Q9Y3Q4]	DRUG	0.020153847
R06AA04	clemastine	C0015672	fatigue	1	[P31645]	DRUG	0.024401265
N06AB06	sertraline	C0019080	hemorrhage	1	[P11712]	DRUG	0.09498999
N06AA10	nortriptyline	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.004408314
N03AX16	pregabalin	C0678222	breast cancer	1	[Q01650]	DRUG	0.463452054
L04AX04	lenalidomide	C0231218	malaise	1	[Q08499]	DRUG	0.016169699
N03AX09	lamotrigine	C0027813	neuritis	1	[P08183]	DRUG	0.052057421
N03AB02	phenytoin	C0014544	epilepsy	4	[P08183, P35498, Q99250, Q9NY46]	DRUG_AND_METABOLITE	0.002274069
G03DA04	progesterone	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.105159238
N06AA04	clomipramine	C0231218	malaise	1	[Q8NER1]	METABOLITE	0.050141944
C09CA07	telmisartan	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.03490134
L02BG06	exemestane	C0018801	heart failure	1	[Q12809]	METABOLITE	0.045375219
C01BC04	flecainide	C0020538	hypertension	2	[P22460, P11712]	DRUG	0.044396476
L01BA01	methotrexate	C0520474	osteonecrosis	2	[P42898, P08183]	DRUG	0.008119381
P01BA01	chloroquine	C0003123	anorexia	1	[P01375]	DRUG	0.073741268
L04AA06	mycophenolic acid	C0023530	leukopenia	2	[O60656, P22309]	DRUG_AND_METABOLITE	0.000794668
N03AF01	carbamazepine	C0015230	rash	2	[P28223, P08908]	DRUG	0.077843187
N05BE01	buspirone	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.06589552
C09AA04	perindopril	C0149931	migraine	1	[P12821]	DRUG_AND_METABOLITE	0.026766868
D07AD01	clobetasol	C0021311	infection	1	[P04150]	DRUG	0.127583335
C01EB03	indomethacin	C0042109	urticaria	1	[P09917]	DRUG	0.092356341
C09AA04	perindopril	C0033860	psoriasis	1	[P12821]	DRUG_AND_METABOLITE	0.055755321
L04AA06	mycophenolic acid	C0041296	tuberculosis	1	[P37231]	DRUG_AND_METABOLITE	0.177782595
C01BA03	disopyramide	C0009806	constipation	1	[Q14524]	DRUG	0.022436068
C09AA06	quinapril	C0013404	dyspnea	1	[P12821]	DRUG_AND_METABOLITE	0.014460868
N06AX21	duloxetine	C0038358	gastric ulcer	2	[P35354, P23219]	METABOLITE	0.038585711
M01AX01	nabumetone	C0004096	asthma	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.028343005
C10AA07	rosuvastatin	C0021311	infection	1	[P27487]	DRUG	0.264908626
N06AX21	duloxetine	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.056135953
M01AX01	nabumetone	C0004093	asthenia	1	[P35354]	DRUG_AND_METABOLITE	0.017783546
N03AB02	phenytoin	C0018801	heart failure	2	[Q14524, Q12809]	DRUG	0.045657764
N01AX03	ketamine	C0003123	anorexia	1	[P14416]	DRUG	0.071241753
N06AA04	clomipramine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.020093213
C01BA01	quinidine	C0022346	jaundice	1	[Q9Y6L6]	DRUG	0.039346831
C07AA06	timolol	C0001824	agranulocytosis	1	[P08183]	DRUG	0.039009407
J05AF01	zidovudine	C0008031	chest pain	1	[P02768]	DRUG	0.017292056
M01AB05	diclofenac	C0008031	chest pain	1	[P02768]	DRUG	0.03292574
N06AX16	venlafaxine	C0027947	neutropenia	1	[P08183]	DRUG	0.136626787
C09CA03	valsartan	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.038508848
L01AA01	cyclophosphamide	C0018799	heart disease	3	[P23219, P11712, P20813]	DRUG	0.012309865
G02CB03	cabergoline	C0009806	constipation	1	[P41595]	DRUG	0.03222962
A05AA02	ursodeoxycholic acid	C0004096	asthma	1	[P11473]	METABOLITE	0.220108265
H02AB02	dexamethasone	C0026848	myopathy	2	[P10275, P04083]	DRUG_AND_METABOLITE	0.057568219
N04BC05	pramipexole	C0013604	edema	1	[P08588]	DRUG	0.047831182
G03CA03	estradiol	C0231528	myalgia	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.24346963
J02AC01	fluconazole	C0009951	convulsions	1	[P08183]	DRUG	0.108919575
N06DA03	rivastigmine	C0012813	diverticulitis	1	[P31645]	DRUG	0.023338897
N05AH03	olanzapine	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.000963004
G03DA04	progesterone	C0031212	personality disorder	1	[P21397]	METABOLITE	0.052378179
M01AE02	naproxen	C0030920	peptic ulcer	2	[P35354, P23219]	DRUG	0.038064251
N06AA10	nortriptyline	C0018681	headache	1	[P05362]	DRUG	0.09082074
B05BC01	mannitol	C0035455	rhinitis	1	[P11226]	METABOLITE	0.207982133
L01AX03	temozolomide	C0014130	Endocrine Disorders	1	[P04798]	METABOLITE	0.125204747
N06AX16	venlafaxine	C0010709	cyst	6	[P32238, P08183, P32239, P23975, P17252, P29475]	DRUG	0.499995859
N07XX02	riluzole	C0497327	dementia	1	[O00555]	DRUG	0.164862469
M01AX01	nabumetone	C0027726	nephrotic syndrome	2	[P15121, P35354]	DRUG_AND_METABOLITE	0.015415539
L01BC06	capecitabine	C0019158	hepatitis	2	[P11509, P02768]	METABOLITE	0.023732516
R03AC13	formoterol	C0015230	rash	1	[P07550]	DRUG	0.086440059
G02CB01	bromocriptine	C1456784	paranoia	1	[P05177]	DRUG	0.038457576
P01BA01	chloroquine	C0027947	neutropenia	1	[P08183]	DRUG	0.05490586
C09AA05	ramipril	C0004093	asthenia	1	[P12821]	DRUG	0.010207101
N06AA04	clomipramine	C0575081	abnormal gait	2	[P35498, Q12791]	METABOLITE	0.020093213
N06AB08	fluvoxamine	C0013384	dyskinesia	1	[P14416]	DRUG_AND_METABOLITE	0.087743477
J01AA08	minocycline	C0038362	stomatitis	1	[P01584]	DRUG	0.013961737
N06AB04	citalopram	C0281774	acute psychosis	2	[P35462, P28223]	DRUG	0.00556921
N06AB08	fluvoxamine	C0013390	dysmenorrhea	1	[P04798]	DRUG_AND_METABOLITE	0.018096702
C09AA01	captopril	C0030920	peptic ulcer	2	[P14780, P08473]	DRUG	0.009329478
N02CC04	rizatriptan	C0013146	abuse	1	[P41595]	METABOLITE	0.015405718
C09CA06	candesartan	C0027051	myocardial infarction	3	[P30556, P11712, P23219]	DRUG_AND_METABOLITE	0.010055211
C09CA04	irbesartan	C0021311	infection	2	[P23219, P50052]	DRUG_AND_METABOLITE	0.131621165
G04CA02	tamsulosin	C0018799	heart disease	2	[P23219, P35354]	METABOLITE	0.098858767
S01ED02	betaxolol	C0041912	upper respiratory tract infection	2	[P07550, Q13936]	METABOLITE	0.176516262
C01EB03	indomethacin	C0015230	rash	3	[P37231, Q9Y5Y4, Q13258]	DRUG	0.059765947
S01GX09	olopatadine	C0021311	infection	1	[P04271]	DRUG	0.24606472
L01BC06	capecitabine	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.081756348
N06AX11	mirtazapine	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG	0.059023888
J01MA01	ofloxacin	C0242184	hypoxia	1	[Q12809]	DRUG_AND_METABOLITE	0.263628743
M01AH02	rofecoxib	C0015672	fatigue	3	[P31645, P28223, P35354]	DRUG_AND_METABOLITE	0.000305005
N04BD01	selegiline	C0022661	chronic renal failure	3	[P35348, P35368, Q16853]	DRUG_AND_METABOLITE	0.018800326
M01AB02	sulindac	C0015672	fatigue	1	[P35354]	DRUG_AND_METABOLITE	0.035047926
C10AB02	bezafibrate	C0013595	eczema	2	[P37231, Q07869]	DRUG	0.03322589
N02AA03	hydromorphone	C0497327	dementia	3	[P31645, P17787, P43681]	METABOLITE	0.041004597
L02BG06	exemestane	C0027651	tumor	6	[P11511, P08684, P07437, P10275, P18405, Q12809]	METABOLITE	0.006623557
J01AA08	minocycline	C0038325	Stevens - Johnson syndrome	2	[P08253, P14780]	DRUG	0.000629183
J05AE04	nelfinavir	C0020433	bilirubinemia	2	[P21439, Q9Y6L6]	DRUG_AND_METABOLITE	0.002187811
L04AX04	lenalidomide	C0038363	ulcerative stomatitis	1	[P01375]	DRUG	0.019239124
J01FA09	clarithromycin	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.057691049
A04AA01	ondansetron	C0002792	anaphylaxis	1	[Q15722]	DRUG	0.132653248
N03AB04	mephenytoin	C0027947	neutropenia	2	[Q92887, P08183]	DRUG	0.015024931
C07AA15	carteolol	C0013604	edema	1	[P08588]	DRUG	0.018096702
L04AX04	lenalidomide	C0013395	Dyspepsia	1	[P23219]	DRUG	0.027162705
N06AX16	venlafaxine	C0027813	neuritis	1	[P08183]	DRUG	0.1628433
N04BC04	ropinirole	C0033975	psychosis	6	[P35462, P28223, P21917, Q13639, P28222, P08908]	DRUG	1.16771E-06
L02BB01	flutamide	C0025637	methemoglobinemia	1	[P05177]	DRUG_AND_METABOLITE	0.031415297
C02KX01	bosentan	C0043144	wheezing	1	[P24530]	DRUG_AND_METABOLITE	0.105539171
G02CB01	bromocriptine	C0027051	myocardial infarction	6	[P21554, P07550, P31645, P05177, P08588, P18089]	DRUG	0.035134219
N03AF02	oxcarbazepine	C0020538	hypertension	1	[P20815]	DRUG	0.158026147
C07AB07	bisoprolol	C0021311	infection	1	[P07550]	DRUG_AND_METABOLITE	0.180184941
C08DA01	verapamil	C0018801	heart failure	2	[Q14524, Q12809]	DRUG_AND_METABOLITE	0.059509684
N06AA17	amoxapine	C0013604	edema	1	[P08588]	METABOLITE	0.053677028
N05AX12	aripiprazole	C0026848	myopathy	1	[P17252]	DRUG_AND_METABOLITE	0.265101728
N05AX12	aripiprazole	C0018801	heart failure	3	[Q9Y2I1, Q12809, P07550]	DRUG_AND_METABOLITE	0.019687894
M05BA04	alendronate	C0006826	cancer	2	[P42336, P48736]	DRUG	0.41543493
N05AH03	olanzapine	C0018802	congestive heart failure	2	[Q12809, P07550]	DRUG_AND_METABOLITE	0.069247462
N05AH03	olanzapine	C0018801	heart failure	2	[Q12809, P07550]	DRUG_AND_METABOLITE	0.069247462
C08DA01	verapamil	C0027051	myocardial infarction	4	[P11712, P33261, P31645, P05177]	DRUG	0.117989433
J01MA14	moxifloxacin	C0018790	cardiac arrest	1	[Q12809]	DRUG	0.012425662
M04AA01	allopurinol	C0085096	peripheral vascular disorder	1	[P08107]	METABOLITE	0.277558428
A03FA01	metoclopramide	C0015672	fatigue	1	[P28223]	DRUG	0.043339606
N06AX21	duloxetine	C0007859	neck pain	1	[Q8NER1]	DRUG	0.056135953
N02AA03	hydromorphone	C0023530	leukopenia	2	[O60656, P08183]	DRUG_AND_METABOLITE	0.016499221
N06AX16	venlafaxine	C0033975	psychosis	7	[P35462, P28223, Q13639, P21397, P28222, P31645, P08908]	DRUG	2.63993E-05
N03AX12	gabapentin	C0004134	ataxia	1	[Q9NY47]	DRUG_AND_METABOLITE	0.047756876
A02BA01	cimetidine	C0020517	hypersensitivity	3	[P35367, P25021, Q9H3N8]	DRUG	0.004927408
N05AX12	aripiprazole	C0018799	heart disease	5	[Q12809, P31645, P08588, P07550, P41595]	DRUG_AND_METABOLITE	0.034599004
G04CA03	terazosin	C0149931	migraine	4	[P28223, P21917, P35498, P28335]	DRUG	0.000374019
N05AX12	aripiprazole	C0018790	cardiac arrest	3	[Q12809, P18089, P07550]	DRUG_AND_METABOLITE	0.00260623
C08DA01	verapamil	C0011991	diarrhea	1	[Q92887]	DRUG	0.081790999
N02AA01	morphine	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.010538298
L02BG03	anastrozole	C0024236	lymphedema	1	[P08684]	DRUG_AND_METABOLITE	0.017783546
N06AA04	clomipramine	C0008031	chest pain	1	[P02768]	METABOLITE	0.050141944
N06AB06	sertraline	C0030920	peptic ulcer	1	[P33261]	DRUG	0.100978046
C07AA07	sotalol	C0038454	cerebrovascular accident	1	[P07550]	DRUG	0.107647419
N06AB05	paroxetine	C0013604	edema	1	[P08588]	DRUG	0.042974428
N06AA21	maprotiline	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.001592396
C10AX09	ezetimibe	C0016977	gallbladder disease	1	[P22309]	DRUG	0.027162705
N05AA01	chlorpromazine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.017187412
N03AF01	carbamazepine	C0038220	status epilepticus	1	[P35498]	DRUG	0.059084847
G03AC06	medroxyprogesterone	C0020615	hypoglycemia	2	[P08235, P04150]	DRUG_AND_METABOLITE	0.002343788
N05AH02	clozapine	C0026266	mitral insufficiency	6	[Q12809, P31645, P08588, P11712, P07550, P23975]	DRUG_AND_METABOLITE	0.014940513
C09AA10	trandolapril	C0039231	tachycardia	1	[P12821]	DRUG_AND_METABOLITE	0.00976001
R03AC13	formoterol	C0021311	infection	1	[P07550]	DRUG	0.225075103
C03CA04	torasemide	C0013395	Dyspepsia	1	[P23219]	DRUG	0.012792437
L02BG03	anastrozole	C0030193	pain	1	[P11511]	DRUG	0.017783546
M04AA01	allopurinol	C0022660	acute renal failure	2	[P08107, P00492]	DRUG_AND_METABOLITE	0.022593598
D10AA02	methylprednisolone	C0021311	infection	1	[P04150]	DRUG_AND_METABOLITE	0.225075103
N05CF02	zolpidem	C0019080	hemorrhage	1	[P11712]	DRUG	0.076004516
L01BC06	capecitabine	C0021311	infection	1	[P11387]	METABOLITE	0.447466806
N05AB06	trifluoperazine	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.107647419
R03AC13	formoterol	C0085649	peripheral edema	1	[P08588]	DRUG	0.015405718
N05AH03	olanzapine	C0038363	ulcerative stomatitis	1	[P31645]	DRUG	0.040204533
G03AC06	medroxyprogesterone	C0004096	asthma	1	[P04150]	DRUG_AND_METABOLITE	0.168492591
G03AC06	medroxyprogesterone	C0004093	asthenia	1	[P04150]	DRUG_AND_METABOLITE	0.021841092
C07AA12	nadolol	C0015230	rash	1	[P07550]	DRUG	0.069716619
D05BB02	acitretin	C0151514	skin atrophy	1	[P35354]	METABOLITE	0.203641648
C07AA05	propranolol	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.004167423
M01AB15	ketorolac	C0030305	pancreatitis	1	[P35354]	DRUG	0.116501515
M01AE02	naproxen	C0035078	renal failure	1	[P41222]	DRUG	0.195806584
R01AX03	ipratropium bromide	C0043144	wheezing	2	[P11229, P20309]	DRUG	0.04394482
A10BB09	gliclazide	C0021311	infection	1	[P15692]	DRUG	0.180184941
J01MA14	moxifloxacin	C0018801	heart failure	1	[Q12809]	DRUG	0.022963468
J01MA14	moxifloxacin	C0018802	congestive heart failure	1	[Q12809]	DRUG	0.022963468
M01AH01	celecoxib	C0004623	bacterial infections	1	[P35354]	DRUG_AND_METABOLITE	0.134991257
R03DA04	theophylline	C0036974	shock	1	[P01375]	METABOLITE	0.12507432
N02AA01	morphine	C0011991	diarrhea	1	[O60656]	DRUG	0.060656663
M03BX08	cyclobenzaprine	C0017152	gastritis	1	[P23219]	METABOLITE	0.212234884
L04AX02	thalidomide	C0021400	Influenza	1	[P01375]	DRUG	0.203313836
N05BC01	meprobamate	C0039231	tachycardia	2	[P07550, P08588]	METABOLITE	0.016169699
P02CA03	albendazole	C0023530	leukopenia	1	[P08183]	DRUG	0.044087091
N05AB02	fluphenazine	C0497327	dementia	1	[P08908]	DRUG	0.308225634
N06AA04	clomipramine	C0012833	dizziness	1	[P29274]	METABOLITE	0.050141944
N04BC05	pramipexole	C0007097	carcinoma	4	[P07550, Q9H3N8, Q9Y5N1, P23975]	DRUG	0.499995859
N01BB01	bupivacaine	C0003811	arrhythmia	2	[P22460, Q14524]	METABOLITE	0.00515856
M01AE09	flurbiprofen	C0001824	agranulocytosis	4	[P16662, O60656, P22309, P08246]	DRUG	2.08794E-05
M01AC01	piroxicam	C0030305	pancreatitis	1	[P35354]	DRUG_AND_METABOLITE	0.069985391
N07AX01	pilocarpine	C0010709	cyst	2	[P11509, P05181]	DRUG	0.202920474
L02BG03	anastrozole	C0010709	cyst	2	[P05177, P11511]	DRUG	0.257746653
N06AA04	clomipramine	C0231528	myalgia	3	[P17252, P29475, Q8NER1]	METABOLITE	0.049355201
G04CA03	terazosin	C0042024	urinary incontinence	2	[P28223, P21917]	DRUG	0.007806911
C10AA04	fluvastatin	C0001339	acute pancreatitis	1	[P04798]	DRUG_AND_METABOLITE	0.103777387
N03AG01	valproic acid	C0497327	dementia	1	[P80404]	DRUG	0.327128534
L04AA13	leflunomide	C0009782	connective tissue disorders	1	[P03956]	DRUG	0.022436068
N04BB01	amantadine	C0018524	hallucinations	2	[P08183, P36544]	METABOLITE	0.03417318
A03BA01	atropine	C0011603	dermatitis	3	[P47712, P28223, P08908]	DRUG	0.040204533
N06AB08	fluvoxamine	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.013399503
A10BG03	pioglitazone	C0020456	hyperglycemia	1	[P37231]	DRUG_AND_METABOLITE	0.089912296
C07AG02	carvedilol	C0002792	anaphylaxis	1	[P19320]	DRUG	0.063156875
M03BX08	cyclobenzaprine	C0033975	psychosis	7	[P35462, P28223, P21917, Q13639, P28222, P31645, P08908]	DRUG_AND_METABOLITE	6.31065E-05
M01AB02	sulindac	C0008031	chest pain	1	[P02768]	DRUG	0.016701405
G03CA03	estradiol	C0162566	porphyria cutanea tarda	1	[P05177]	DRUG_AND_METABOLITE	0.061499211
M01AE02	naproxen	C0001824	agranulocytosis	3	[P16662, P22309, P08246]	DRUG	0.002988738
G03CA03	estradiol	C0029408	osteoarthritis	1	[P03372]	DRUG_AND_METABOLITE	0.395435182
N07BC02	methadone	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000299598
C03AA03	hydrochlorothiazide	C0030552	weakness	1	[P55017]	DRUG	0.021299045
C07AB02	metoprolol	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.044574807
S01ED03	levobunolol	C0020615	hypoglycemia	1	[P07550]	DRUG	0.029823411
C09CA04	irbesartan	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.019687894
J05AF05	lamivudine	C0030305	pancreatitis	1	[Q00613]	DRUG	0.116501515
N06AB05	paroxetine	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.028326723
N06AB04	citalopram	C0003873	rheumatoid arthritis	1	[P05177]	DRUG	0.396212585
C09AA04	perindopril	C0016199	flank pain	1	[P12821]	DRUG_AND_METABOLITE	0.002297402
A02BC02	pantoprazole	C0027051	myocardial infarction	5	[P04798, P08575, P11712, P33261, P05177]	DRUG_AND_METABOLITE	0.008661624
L01AA01	cyclophosphamide	C0020517	hypersensitivity	1	[O75762]	METABOLITE	0.06457386
N06AA11	protriptyline	C0020565	breast enlargement	1	[P05362]	DRUG	0.202670332
L01XX11	estramustine	C0008031	chest pain	1	[P02768]	METABOLITE	0.026275405
C09AA03	lisinopril	C0043144	wheezing	1	[P12821]	DRUG	0.092356341
M01AE01	ibuprofen	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.028667207
L01XE03	erlotinib	C0235896	pulmonary infiltration	1	[P20783]	DRUG_AND_METABOLITE	0.135133707
G03DA04	progesterone	C0000786	spontaneous abortion	3	[P06401, P10275, Q16678]	DRUG_AND_METABOLITE	0.013699578
N02AA01	morphine	C0029408	osteoarthritis	1	[P21554]	METABOLITE	0.24963282
J02AC02	itraconazole	C0019158	hepatitis	1	[P05181]	DRUG_AND_METABOLITE	0.063596471
N06AA11	protriptyline	C0020538	hypertension	13	[P20815, P35348, P13945, P07550, P21728, O15244, P31645, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG	1.54047E-05
G03HA01	cyproterone	C0699885	bladder carcinoma	1	[P10275]	DRUG	0.069387739
L04AX04	lenalidomide	C0004096	asthma	4	[P01375, P35354, P23219, Q08499]	DRUG	0.009329478
L04AX04	lenalidomide	C0004093	asthenia	1	[P35354]	DRUG	0.034147949
C01EB03	indomethacin	C0009324	ulcerative colitis	4	[P10145, P08183, P35354, P37231]	DRUG	0.021820668
N06AB08	fluvoxamine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.033221489
N05AX08	risperidone	C0151744	myocardial ischemia	3	[P07550, P08588, Q12809]	DRUG_AND_METABOLITE	0.011475973
H02AB06	prednisolone	C0018802	congestive heart failure	1	[P08235]	DRUG_AND_METABOLITE	0.114588485
C01BD01	amiodarone	C0242184	hypoxia	2	[Q14524, Q12809]	DRUG	0.13769506
N06AX06	nefazodone	C0042109	urticaria	1	[P07550]	METABOLITE	0.081682023
N06AB05	paroxetine	C0042024	urinary incontinence	2	[P08172, P28223]	DRUG	0.00560082
N06BA07	modafinil	C1527304	allergic reaction	1	[Q01959]	DRUG	0.048595777
C07AA05	propranolol	C0011991	diarrhea	1	[P46098]	DRUG	0.063596471
N06BC01	caffeine	C0151908	dry skin	1	[Q07343]	DRUG_AND_METABOLITE	0.225059161
N02CC01	sumatriptan	C0007820	cerebrovascular disorder	2	[P28223, P07550]	DRUG	0.15545058
N05AX12	aripiprazole	C0018524	hallucinations	1	[P36544]	DRUG_AND_METABOLITE	0.199608332
L04AX02	thalidomide	C0038358	gastric ulcer	3	[P01375, P35354, P23219]	DRUG_AND_METABOLITE	0.008887027
D01AC01	clotrimazole	C0019080	hemorrhage	1	[P11712]	DRUG	0.09498999
L04AX02	thalidomide	C0038363	ulcerative stomatitis	1	[P01375]	DRUG	0.058400414
C01BA01	quinidine	C0002874	aplastic anemia	1	[P04798]	DRUG	0.202920474
M01AB02	sulindac	C0011603	dermatitis	4	[P37231, Q9Y5Y4, Q13258, Q07869]	METABOLITE	0.005208238
C08CA06	nimodipine	C0020538	hypertension	2	[P20815, P08235]	DRUG	0.077866045
N06AX21	duloxetine	C0010200	cough	1	[Q8NER1]	DRUG	0.04687583
C09AA02	enalapril	C0015672	fatigue	1	[P12821]	DRUG_AND_METABOLITE	0.023218364
C09AA08	cilazapril	C0038454	cerebrovascular accident	1	[P12821]	DRUG	0.05696568
N01BA02	procaine	C0020517	hypersensitivity	1	[Q01959]	DRUG	0.158026147
L01CB01	etoposide	C0020538	hypertension	1	[P20815]	DRUG_AND_METABOLITE	0.275045545
N03AB02	phenytoin	C0020538	hypertension	2	[P20815, P11712]	DRUG_AND_METABOLITE	0.248968302
A02BC04	rabeprazole	C0019151	hepatic encephalopathy	3	[P14867, P18505, P18507]	DRUG	7.29447E-05
L02BA01	tamoxifen	C0042487	venous thrombosis	2	[P03372, Q92731]	DRUG_AND_METABOLITE	0.033723271
N06AB04	citalopram	C0003123	anorexia	6	[P28223, P28335, P28221, P31645, P23975, P14416]	DRUG	1.48976E-07
N02AA05	oxycodone	C0003123	anorexia	3	[P41143, P31645, P23975]	DRUG	0.000104917
N05AG02	pimozide	C0686347	tardive dyskinesia	1	[P35498]	DRUG	0.085428589
N01BA02	procaine	C0020538	hypertension	1	[P18054]	METABOLITE	0.433894116
N06AA12	doxepin	C0023530	leukopenia	2	[Q07817, P08183]	DRUG_AND_METABOLITE	0.069528009
N05AB06	trifluoperazine	C0015230	rash	6	[P07550, P28223, P08908, P31645, P17405, P04629]	DRUG	0.051340752
A07EA06	budesonide	C0017601	glaucoma	2	[Q16678, P04150]	DRUG_AND_METABOLITE	0.017783546
A02BC02	pantoprazole	C0022346	jaundice	1	[Q9Y6L6]	DRUG	0.026665834
N03AF01	carbamazepine	C0015672	fatigue	2	[P28223, P35354]	METABOLITE	0.002877124
N01BB09	ropivacaine	C0009951	convulsions	4	[P35498, P08183, Q99250, Q9NY46]	METABOLITE	0.004408314
A02BC04	rabeprazole	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG_AND_METABOLITE	0.011163266
N06AB05	paroxetine	C0442874	neuropathy	1	[P08183]	DRUG	0.13763063
H05BX01	cinacalcet	C0015672	fatigue	1	[P31645]	DRUG	0.020490582
M01AE02	naproxen	C0023530	leukopenia	3	[P16662, P22309, P08246]	DRUG	0.005652463
N04BB01	amantadine	C0018790	cardiac arrest	1	[P18089]	DRUG	0.079709923
N06AB05	paroxetine	C0600139	prostate cancer	4	[P08183, P10632, P20813, P35348]	DRUG	0.488670018
C07AG01	labetalol	C0004093	asthenia	1	[P28223]	DRUG	0.023218364
C09AA01	captopril	C0013404	dyspnea	1	[P12821]	DRUG	0.048334546
N06AX16	venlafaxine	C0033860	psoriasis	1	[Q05586]	METABOLITE	0.380934706
N04BC02	pergolide	C0684249	lung cancer	1	[P08684]	DRUG	0.468483724
N05BC01	meprobamate	C0039070	syncope	1	[P29274]	METABOLITE	0.105016252
A03FA02	cisapride	C0025637	methemoglobinemia	1	[P05177]	DRUG	0.029036603
M04AA01	allopurinol	C0030193	pain	1	[Q08499]	METABOLITE	0.07026785
N06AB03	fluoxetine	C0003873	rheumatoid arthritis	1	[P05177]	DRUG	0.477421621
M01AE03	ketoprofen	C0009324	ulcerative colitis	2	[P10145, P35354]	DRUG	0.040753047
L01XE02	gefitinib	C0015230	rash	1	[P04629]	DRUG_AND_METABOLITE	0.499995859
C10AA06	cerivastatin	C0009319	colitis	1	[P08183]	DRUG_AND_METABOLITE	0.140240596
C10AA02	lovastatin	C0018681	headache	2	[P05362, P29475]	METABOLITE	0.059946991
A07EA06	budesonide	C0041912	upper respiratory tract infection	5	[P35228, P05113, P35354, P23219, P09917]	METABOLITE	0.076642524
N06BA09	atomoxetine	C0039070	syncope	1	[P29274]	DRUG	0.05856492
N06AB06	sertraline	C0007820	cerebrovascular disorder	1	[P28223]	DRUG_AND_METABOLITE	0.273270497
N06AX06	nefazodone	C0042024	urinary incontinence	1	[P28223]	DRUG_AND_METABOLITE	0.065368111
L04AA06	mycophenolic acid	C0034069	pulmonary fibrosis	1	[P37231]	DRUG_AND_METABOLITE	0.041008297
C07AB07	bisoprolol	C0015230	rash	1	[P07550]	DRUG_AND_METABOLITE	0.069716619
N02AA03	hydromorphone	C0033975	psychosis	4	[P21964, P35462, P21917, P31645]	METABOLITE	0.000627876
N06AX16	venlafaxine	C0042024	urinary incontinence	3	[P08172, P28223, P29475]	DRUG	0.001830604
H02AB02	dexamethasone	C0015230	rash	1	[P47712]	METABOLITE	0.269787469
N06AX16	venlafaxine	C0042109	urticaria	1	[P07550]	DRUG	0.12340561
A02BC04	rabeprazole	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.116972229
N06AB05	paroxetine	C0149931	migraine	3	[P28223, P31645, P28335]	DRUG	0.002473457
C09AA08	cilazapril	C0003811	arrhythmia	1	[P12821]	DRUG	0.013961737
L01XE02	gefitinib	C0085786	fibrosing alveolitis	3	[P20783, P04626, Q05655]	DRUG_AND_METABOLITE	0.188255942
A02BC04	rabeprazole	C0497327	dementia	1	[P50993]	METABOLITE	0.334303611
L02BA01	tamoxifen	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.084863615
N02AA03	hydromorphone	C0021311	infection	2	[P23219, P01189]	METABOLITE	0.388888656
M01AX01	nabumetone	C0015672	fatigue	1	[P35354]	DRUG_AND_METABOLITE	0.017783546
N06AA12	doxepin	C0015230	rash	6	[P07550, P28223, P08908, P31645, P17405, P04629]	DRUG	0.029147785
L04AA06	mycophenolic acid	C0023895	liver disease	1	[P37231]	DRUG_AND_METABOLITE	0.054232974
S01ED04	metipranolol	C0027051	myocardial infarction	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.010552172
C10AA02	lovastatin	C0002878	hemolytic anemia	2	[O95479, P11413]	METABOLITE	0.12665733
L01XX35	anagrelide	C0006826	cancer	1	[P05177]	DRUG	0.485588031
N05AH02	clozapine	C1456784	paranoia	1	[P05177]	DRUG	0.048676004
N01BB09	ropivacaine	C0009806	constipation	1	[Q14524]	METABOLITE	0.038827414
N01BB01	bupivacaine	C0162297	respiratory arrest	1	[Q9UQD0]	DRUG_AND_METABOLITE	0.07026785
N06AB05	paroxetine	C0006325	bruxism	1	[P31645]	DRUG_AND_METABOLITE	0.018505915
N01BA02	procaine	C0018790	cardiac arrest	1	[Q14524]	DRUG	0.098169818
G03DA04	progesterone	C1527304	allergic reaction	1	[P35367]	METABOLITE	0.194264552
N06AB05	paroxetine	C0006370	bulimia	2	[P31645, P28335]	DRUG	0.003713939
B05BC01	mannitol	C0042487	venous thrombosis	2	[P01008, P29460]	METABOLITE	0.105110535
N06BA01	amphetamine	C0018524	hallucinations	1	[P36544]	METABOLITE	0.270130522
B01AC07	dipyridamole	C0878544	cardiomyopathy	2	[O76074, O15440]	DRUG	0.022806456
N05AH03	olanzapine	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.103034195
N06AB05	paroxetine	C0013146	abuse	1	[P41595]	DRUG	0.028123725
C03DB01	amiloride	C0034063	pulmonary edema	1	[P37088]	DRUG	0.037532924
N01BA02	procaine	C1527304	allergic reaction	1	[Q01959]	DRUG	0.127583335
N06AX21	duloxetine	C0010054	coronary artery disease	5	[P08684, P35354, P02768, P21554, P06276]	DRUG	0.095108888
N05AX08	risperidone	C0027051	myocardial infarction	5	[P21554, P07550, P31645, P08588, P18089]	DRUG_AND_METABOLITE	0.088450647
A07EC01	sulfasalazine	C0019158	hepatitis	3	[P05181, P23219, P35354]	DRUG_AND_METABOLITE	0.00404289
N05AX08	risperidone	C0027059	myocarditis	2	[Q12809, P08588]	DRUG_AND_METABOLITE	0.094244523
N05AH03	olanzapine	C0042133	uterine fibroids	1	[Q12809]	DRUG_AND_METABOLITE	0.2835329
P02CA03	albendazole	C0023895	liver disease	1	[P08684]	DRUG	0.089912296
N04BB01	amantadine	C0018802	congestive heart failure	1	[Q9Y2I1]	DRUG	0.15098677
N04BC05	pramipexole	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG	0.004585386
J01DB04	cefazolin	C0022658	nephropathy	1	[P02768]	DRUG	0.078146652
G03HA01	cyproterone	C0030193	pain	1	[P11511]	DRUG	0.007907224
N06AB05	paroxetine	C0020538	hypertension	9	[P35348, P21728, P31645, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG	3.60068E-05
D06AX07	gentamicin	C1527304	allergic reaction	1	[O75762]	DRUG	0.035047926
N06AB05	paroxetine	C0020569	salivary gland enlargement	1	[P20309]	DRUG	0.133868815
N06AB05	paroxetine	C0020565	breast enlargement	2	[Q9UBN4, Q9Y210]	DRUG	0.028123725
G04CB02	dutasteride	C0006826	cancer	4	[P20815, P18405, P08684, P31213]	DRUG_AND_METABOLITE	0.045211647
R06AX02	cyproheptadine	C0018524	hallucinations	4	[P36544, P35498, Q99250, Q9NY46]	DRUG	0.003783563
N03AX09	lamotrigine	C0023530	leukopenia	1	[P08183]	DRUG	0.053194386
R03DA04	theophylline	C0151636	ventricular extrasystoles	1	[P48029]	DRUG	0.019300365
N06AB05	paroxetine	C0020542	pulmonary hypertension	3	[Q9Y210, P31645, Q9UBN4]	DRUG	0.003144473
N06AB05	paroxetine	C0020550	hyperthyroidism	1	[P08183]	DRUG	0.112841395
G03AC06	medroxyprogesterone	C0040046	thrombophlebitis	1	[P03372]	DRUG_AND_METABOLITE	0.054879508
N06AX06	nefazodone	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG_AND_METABOLITE	2.76314E-06
S01ED03	levobunolol	C0006266	bronchospasm	1	[P07550]	DRUG	0.118929624
R03AC13	formoterol	C1458155	breast neoplasm	1	[P11509]	DRUG	0.443800819
N02AX02	tramadol	C1458155	breast neoplasm	3	[P08684, P20813, P23975]	DRUG_AND_METABOLITE	0.372777191
J05AE03	ritonavir	C0149931	migraine	1	[P08684]	DRUG	0.072738991
L01XE03	erlotinib	C0231528	myalgia	2	[Q09013, P24723]	DRUG_AND_METABOLITE	0.308816105
J05AF01	zidovudine	C0004093	asthenia	1	[P28223]	METABOLITE	0.036033671
M01AB05	diclofenac	C0004096	asthma	4	[P10145, P35354, P23219, P33527]	DRUG	0.103517096
M01AB05	diclofenac	C0004093	asthenia	2	[P28223, P35354]	DRUG_AND_METABOLITE	0.008292374
C08CA06	nimodipine	C0018801	heart failure	1	[P08235]	DRUG	0.08498899
C08CA06	nimodipine	C0018802	congestive heart failure	1	[P08235]	DRUG	0.08498899
L01XX35	anagrelide	C0003123	anorexia	3	[P28223, P28335, P28221]	METABOLITE	0.000200103
M01AE09	flurbiprofen	C0030920	peptic ulcer	3	[P35354, P10145, P23219]	DRUG_AND_METABOLITE	0.00124633
A03FA01	metoclopramide	C0015230	rash	2	[P28223, P08908]	DRUG	0.074805403
D01AC08	ketoconazole	C0011603	dermatitis	1	[P09601]	DRUG	0.344469243
R06AX17	ketotifen	C0042109	urticaria	1	[P09917]	DRUG	0.063596471
G03XC01	raloxifene	C0011849	diabetes mellitus	2	[P08684, P10632]	DRUG	0.082415968
R01AD01	beclomethasone	C0013390	dysmenorrhea	2	[P35354, P04798]	DRUG_AND_METABOLITE	0.000499504
R03DC03	montelukast	C0002792	anaphylaxis	1	[Q9NS75]	DRUG_AND_METABOLITE	0.034852775
N05AB06	trifluoperazine	C0015672	fatigue	3	[P31645, P28223, P35354]	DRUG	0.003621379
C07AG02	carvedilol	C0878544	cardiomyopathy	4	[P16860, P17302, Q12809, P08588]	DRUG_AND_METABOLITE	0.000434556
M01AC06	meloxicam	C0041912	upper respiratory tract infection	3	[P35354, P23219, P09917]	DRUG	0.025266024
R06AD02	promethazine	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.014431164
A04AA02	granisetron	C0020517	hypersensitivity	1	[P41595]	DRUG	0.089763822
C03CA01	furosemide	C0023530	leukopenia	1	[Q92887]	DRUG	0.079913137
N06BA09	atomoxetine	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.004479573
N06BA09	atomoxetine	C0039239	sinus tachycardia	2	[P07550, P08588]	DRUG	0.004479573
N06AX21	duloxetine	C0085649	peripheral edema	1	[P08588]	DRUG	0.087386772
N03AF02	oxcarbazepine	C0018801	heart failure	1	[Q14524]	DRUG	0.058400414
L04AX04	lenalidomide	C0243026	sepsis	1	[P01375]	DRUG	0.128824251
G03CA03	estradiol	C0029925	ovarian cancer	13	[Q9UNQ0, P08183, P04278, P11474, P50225, P22309, Q16678, P10275, P08684, P05177, P03372, Q92731, P10632]	DRUG	0.004163713
L01XE01	imatinib	C0018799	heart disease	8	[P23219, P11712, Q13557, Q15831, Q9Y243, P28482, Q9NRM7, P27361]	DRUG	0.331084559
C07AA15	carteolol	C0038454	cerebrovascular accident	1	[P07550]	DRUG	0.095163322
G02CB01	bromocriptine	C0033375	prolactinoma	1	[P14416]	DRUG_AND_METABOLITE	0.05856492
C07AA07	sotalol	C0008031	chest pain	1	[P02768]	DRUG	0.010781267
C08DB01	diltiazem	C0015230	rash	2	[P28223, P08908]	DRUG	0.074805403
A02BA01	cimetidine	C0027947	neutropenia	1	[P08183]	DRUG	0.085892844
M04AA01	allopurinol	C0030305	pancreatitis	2	[P08107, Q00613]	METABOLITE	0.155820876
N03AX09	lamotrigine	C0027947	neutropenia	1	[P08183]	DRUG	0.044574807
M01AE01	ibuprofen	C0220981	metabolic acidosis	1	[Q16790]	METABOLITE	0.066764793
A04AD12	aprepitant	C0010709	cyst	2	[P05177, P20815]	DRUG_AND_METABOLITE	0.173579836
A04AA02	granisetron	C0020538	hypertension	2	[P20815, P28223]	DRUG	0.115998799
C07AA06	timolol	C0020615	hypoglycemia	1	[P07550]	DRUG	0.045375219
N03AF01	carbamazepine	C0003811	arrhythmia	1	[Q14524]	DRUG	0.049485821
C09AA04	perindopril	C0033687	proteinuria	1	[P12821]	DRUG_AND_METABOLITE	0.019687894
J05AE01	saquinavir	C0002871	anemia	1	[P02768]	DRUG	0.091184812
L01XX35	anagrelide	C0011991	diarrhea	1	[P46098]	METABOLITE	0.03201379
M01AH03	valdecoxib	C0699885	bladder carcinoma	3	[P35354, Q16790, P33261]	DRUG_AND_METABOLITE	0.133141619
N05AB06	trifluoperazine	C1527304	allergic reaction	7	[P41595, Q8NER1, Q01959, P29475, P35367, P25021, Q9H3N8]	DRUG	3.62975E-05
N06AX21	duloxetine	C0022658	nephropathy	2	[P02768, P23219]	METABOLITE	0.16626284
A08AA10	sibutramine	C0013146	abuse	1	[P41595]	DRUG_AND_METABOLITE	0.019687894
J02AC01	fluconazole	C0023530	leukopenia	1	[P08183]	DRUG	0.044087091
M01AH02	rofecoxib	C0011615	atopic dermatitis	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.056501401
N05AA01	chlorpromazine	C0042109	urticaria	2	[P07550, P09917]	DRUG	0.053146369
C07AB04	acebutolol	C0033975	psychosis	2	[P28222, P08908]	DRUG	0.004137789
C02KX01	bosentan	C0004096	asthma	1	[P24530]	DRUG_AND_METABOLITE	0.105539171
N06AB05	paroxetine	C0020456	hyperglycemia	1	[Q9Y210]	DRUG	0.124559086
N06AX16	venlafaxine	C0010054	coronary artery disease	2	[P08684, P21554]	METABOLITE	0.326577116
C08CA01	amlodipine	C0024117	COPD	2	[P04798, P05177]	DRUG	0.065443783
N06AX06	nefazodone	C0009951	convulsions	3	[P08183, P08908, P31645]	DRUG_AND_METABOLITE	0.039009407
C01BD01	amiodarone	C0020550	hyperthyroidism	1	[P08183]	DRUG	0.090729349
L02BG06	exemestane	C0027051	myocardial infarction	1	[P10275]	METABOLITE	0.132493067
N06AA04	clomipramine	C0004134	ataxia	2	[P35498, Q14643]	METABOLITE	0.088258057
M01AB05	diclofenac	C0033975	psychosis	5	[P35462, P28223, P21917, P28222, P08908]	DRUG	0.000407317
M01AH01	celecoxib	C0041912	upper respiratory tract infection	4	[P35354, P23219, Q16539, P09917]	DRUG	0.30462376
L04AA06	mycophenolic acid	C0041582	ulcer	1	[P37231]	DRUG_AND_METABOLITE	0.016169699
N06BA09	atomoxetine	C0011991	diarrhea	1	[P46098]	DRUG	0.084411206
N06AB03	fluoxetine	C0023530	leukopenia	1	[P08183]	DRUG	0.120354288
C04AD03	pentoxifylline	C0018681	headache	1	[P01375]	DRUG_AND_METABOLITE	0.030530396
A10BB09	gliclazide	C0013295	duodenal ulcer	1	[P33261]	DRUG	0.021227014
S01ED03	levobunolol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.045375219
N01AH01	fentanyl	C0009806	constipation	1	[P41595]	DRUG	0.026766868
C09CA01	losartan	C0004604	back pain	1	[P12821]	DRUG	0.009287022
G03AC06	medroxyprogesterone	C0011570	mental depression	2	[P08684, P03372]	DRUG_AND_METABOLITE	0.00358369
N05BA01	diazepam	C0004096	asthma	1	[P23219]	DRUG	0.418635646
N06AA01	desipramine	C0004134	ataxia	1	[P35498]	DRUG	0.179668419
M01AB08	etodolac	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.074349356
L01XE01	imatinib	C0018801	heart failure	3	[Q13557, Q16539, P12931]	DRUG_AND_METABOLITE	0.232839177
L01XE01	imatinib	C0018802	congestive heart failure	3	[Q13557, Q16539, P12931]	DRUG_AND_METABOLITE	0.232839177
N06AX05	trazodone	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.105027437
G04BE07	apomorphine	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.005067209
C02CA04	doxazosin	C0684249	lung cancer	3	[P04818, P08183, P33261]	DRUG	0.151904753
M01AH03	valdecoxib	C0006266	bronchospasm	3	[P35354, P23219, P33527]	DRUG_AND_METABOLITE	0.168674498
C10AA03	pravastatin	C0026848	myopathy	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.124957776
N06AB08	fluvoxamine	C1269683	major depressive disorder	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.000299598
L04AA06	mycophenolic acid	C0011991	diarrhea	1	[O60656]	DRUG_AND_METABOLITE	0.017783546
J05AF02	didanosine	C0341047	parotid gland enlargement	1	[P54098]	METABOLITE	0.097706703
N06AA09	amitriptyline	C0027051	myocardial infarction	13	[P02768, P21554, P13945, P05362, P06276, P07550, P11712, P33261, P31645, P23219, P05177, P08588, P18089]	DRUG_AND_METABOLITE	0.00316216
L01XE02	gefitinib	C0003123	anorexia	1	[Q16620]	DRUG_AND_METABOLITE	0.382742428
A02BC02	pantoprazole	C0149931	migraine	2	[P50993, P08684]	DRUG_AND_METABOLITE	0.014025764
G03DA04	progesterone	C0029925	ovarian cancer	13	[O95342, Q9UNQ0, P08183, P06401, P04278, P11511, Q16678, P10275, P08684, P05177, P03372, Q92731, P10632]	DRUG_AND_METABOLITE	0.011111366
M01AB15	ketorolac	C0034065	pulmonary embolism	1	[P02768]	DRUG	0.031878908
G03BA03	testosterone	C0004093	asthenia	1	[P08185]	METABOLITE	0.089763822
G03BA03	testosterone	C0004096	asthma	1	[O94956]	METABOLITE	0.48545496
N03AX16	pregabalin	C0014544	epilepsy	1	[O00555]	DRUG	0.063596471
C01EB03	indomethacin	C0023418	leukemia	6	[P42330, P08183, P10828, P10145, P37231, P35354]	DRUG_AND_METABOLITE	0.103977659
S01EC01	acetazolamide	C0220981	metabolic acidosis	1	[Q16790]	DRUG	0.027162705
M01AB08	etodolac	C0004096	asthma	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.059662382
M01AB08	etodolac	C0004093	asthenia	1	[P35354]	DRUG_AND_METABOLITE	0.025953097
D05BB02	acitretin	C0008031	chest pain	1	[P02768]	DRUG_AND_METABOLITE	0.019028106
M01AH02	rofecoxib	C0007117	basal cell carcinoma	1	[P35354]	DRUG_AND_METABOLITE	0.183108043
S01AA14	penicillin G	C0022658	nephropathy	2	[P00915, P00918]	METABOLITE	0.074629948
L04AX02	thalidomide	C0019158	hepatitis	5	[P01375, Q8TD30, P05181, P23219, P35354]	DRUG_AND_METABOLITE	0.004360114
N03AB02	phenytoin	C0006384	bundle branch block	1	[Q14524]	DRUG	0.013636188
N06AA11	protriptyline	C0027051	myocardial infarction	11	[P02768, P13945, P05362, P07550, P11712, P33261, P31645, P23219, P05177, P08588, P18089]	DRUG	0.000635128
M01AE09	flurbiprofen	C1458140	bleeding diathesis	1	[P11712]	DRUG	0.086839232
C07AA07	sotalol	C0004096	asthma	1	[P07550]	DRUG	0.179324562
A02BC01	omeprazole	C0026821	muscle cramps	1	[Q8NER1]	DRUG	0.025719012
C10AA04	fluvastatin	C0015230	rash	3	[P37231, P21731, Q07869]	METABOLITE	0.005743402
L01XE01	imatinib	C0013395	Dyspepsia	1	[P23219]	DRUG	0.161491924
S01ED03	levobunolol	C0018790	cardiac arrest	1	[P07550]	DRUG	0.024401265
N06AA09	amitriptyline	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.157350877
N05BA01	diazepam	C0004134	ataxia	1	[P35498]	DRUG	0.132653248
C09AA04	perindopril	C0006266	bronchospasm	1	[P12821]	DRUG_AND_METABOLITE	0.092356341
J05AF03	zalcitabine	C0020538	hypertension	2	[P20815, P11712]	DRUG	0.163589342
C09AA05	ramipril	C0039231	tachycardia	1	[P12821]	DRUG	0.007907224
L04AA06	mycophenolic acid	C0007097	carcinoma	2	[P37231, P22309]	DRUG_AND_METABOLITE	0.205837624
M01AB15	ketorolac	C0020456	hyperglycemia	3	[P35354, P10145, P07148]	DRUG	0.000796088
N05AH04	quetiapine	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
C02CA04	doxazosin	C0026650	movement disorders	1	[P14416]	METABOLITE	0.061166635
N06AB08	fluvoxamine	C0007097	carcinoma	7	[P05181, P08183, P20815, P04798, P08684, P05177, P23975]	DRUG_AND_METABOLITE	0.213559771
L02BA01	tamoxifen	C0003123	anorexia	1	[P14416]	METABOLITE	0.111998404
G03AC06	medroxyprogesterone	C0085669	acute leukemia	3	[P08183, P04150, P03372]	DRUG_AND_METABOLITE	0.03007953
N06AX05	trazodone	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG_AND_METABOLITE	1.0768E-05
A02BC04	rabeprazole	C0007097	carcinoma	10	[P35354, P08183, Q9UNQ0, P23219, Q16678, P47712, P10632, P04798, P08684, P05177]	DRUG_AND_METABOLITE	0.425031225
N05AB03	perphenazine	C0004096	asthma	1	[P20309]	DRUG	0.369658864
C03BA11	indapamide	C0024115	lung disorder	1	[P51787]	DRUG_AND_METABOLITE	0.229299288
L02BG03	anastrozole	C0010054	coronary artery disease	1	[P08684]	DRUG_AND_METABOLITE	0.135133707
R06AA04	clemastine	C0003123	anorexia	4	[P21917, P31645, P23975, P14416]	DRUG	4.59674E-06
N05CF01	zopiclone	C0004096	asthma	1	[P23219]	DRUG	0.280349021
L01XE01	imatinib	C0018939	blood dyscrasia	1	[P43403]	DRUG	0.190849685
C01EB03	indomethacin	C0030920	peptic ulcer	5	[P35354, P10145, P33261, P37231, P23219]	DRUG_AND_METABOLITE	4.69075E-05
N06AX16	venlafaxine	C0042514	ventricular tachycardia	2	[Q14524, P08588]	DRUG	0.007694259
N06AX16	venlafaxine	C0042510	ventricular fibrillation	1	[Q14524]	METABOLITE	0.031285789
C10AA06	cerivastatin	C0231528	myalgia	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.073232497
N06AX05	trazodone	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.001041147
L04AA06	mycophenolic acid	C0011849	diabetes mellitus	2	[P12268, P37231]	DRUG_AND_METABOLITE	0.018573346
D06AA01	demeclocycline	C0024141	lupus	1	[Q9H244]	DRUG	0.226009783
B01AA03	warfarin	C0002871	anemia	1	[P02768]	DRUG	0.061427537
C01EB03	indomethacin	C0035078	renal failure	2	[P08183, P41222]	DRUG_AND_METABOLITE	0.047831182
N01BB01	bupivacaine	C0020517	hypersensitivity	1	[P00533]	METABOLITE	0.122883547
N06AB08	fluvoxamine	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.033221489
C09CA01	losartan	C0020615	hypoglycemia	1	[P12821]	DRUG	0.074342707
H03BA02	propylthiouracil	C0040034	thrombocytopenia	1	[P07202]	DRUG_AND_METABOLITE	0.013961737
N01BB01	bupivacaine	C0020538	hypertension	4	[P20815, P22460, P11712, P18054]	METABOLITE	0.04049837
R03DA04	theophylline	C0024117	COPD	8	[P01375, P29274, Q08499, P47989, P27815, P05181, P04798, P05177]	DRUG_AND_METABOLITE	0.000772249
L04AX02	thalidomide	C0341047	parotid gland enlargement	1	[P01375]	DRUG	0.269787469
N06AB03	fluoxetine	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG_AND_METABOLITE	4.98612E-06
L02BB03	bicalutamide	C0006826	cancer	4	[P06401, P03372, P08684, P10275]	DRUG_AND_METABOLITE	0.017223047
N05AH04	quetiapine	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.005292839
C02CA04	doxazosin	C0013595	eczema	2	[P28223, P08908]	METABOLITE	0.045203907
J05AF05	lamivudine	C0002792	anaphylaxis	1	[Q00613]	DRUG	0.052801061
N03AX11	topiramate	C0009951	convulsions	2	[P35498, Q99250]	DRUG	0.042804682
C02CA01	prazosin	C0009806	constipation	2	[P46098, P41595]	DRUG	0.00363511
C09AA02	enalapril	C0006266	bronchospasm	1	[P12821]	DRUG_AND_METABOLITE	0.179324562
C09CA04	irbesartan	C0019158	hepatitis	2	[P23219, P05412]	DRUG_AND_METABOLITE	0.008034824
J05AE01	saquinavir	C0026848	myopathy	1	[Q9Y6L6]	DRUG	0.128451012
A03FA02	cisapride	C0013604	edema	1	[P08588]	DRUG	0.044396476
L04AX02	thalidomide	C0002871	anemia	1	[P01375]	DRUG	0.277397428
L04AX02	thalidomide	C0002874	aplastic anemia	2	[P01375, P04798]	DRUG	0.164984258
N06BA07	modafinil	C0013395	Dyspepsia	1	[P21964]	DRUG	0.019687894
H05BX01	cinacalcet	C0015230	rash	1	[P31645]	DRUG	0.100741343
M04AA01	allopurinol	C0003123	anorexia	1	[P27487]	METABOLITE	0.193138681
N05AH04	quetiapine	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.499236835
N06AA10	nortriptyline	C0020538	hypertension	13	[P20815, P35348, P13945, P07550, P21728, O15244, P31645, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG	1.54047E-05
A10BB09	gliclazide	C0019158	hepatitis	1	[P02768]	DRUG	0.039346831
M01AB15	ketorolac	C0020538	hypertension	1	[P11712]	DRUG	0.250256312
C09CA02	eprosartan	C0020443	hypercholesterolemia	1	[P30556]	DRUG	0.033221489
A02BC01	omeprazole	C0085584	encephalopathy	1	[P08183]	DRUG_AND_METABOLITE	0.113185993
A04AD12	aprepitant	C0027651	tumor	5	[P08684, P05177, P25103, P20815, P33261]	DRUG_AND_METABOLITE	0.058880498
C07AA06	timolol	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	1.64872E-05
N06AA10	nortriptyline	C0020565	breast enlargement	1	[P05362]	DRUG	0.202670332
N06AA11	protriptyline	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.005979133
C01BC04	flecainide	C0085610	sinus bradycardia	1	[Q14524]	DRUG	0.010207101
D08AC02	chlorhexidine	C0020538	hypertension	2	[P14780, P08253]	DRUG	0.028748417
C07AB07	bisoprolol	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.020490582
L01BA01	methotrexate	C0022658	nephropathy	2	[P02768, P47989]	DRUG	0.042804682
N02AA03	hydromorphone	C0009319	colitis	2	[P08183, P31645]	METABOLITE	0.100645764
N05AB06	trifluoperazine	C0040822	tremor	1	[Q14643]	DRUG	0.080976776
N06AB05	paroxetine	C0025202	melanoma	2	[P08183, P20309]	DRUG	0.38801716
M01AH02	rofecoxib	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.077261871
P01BC02	mefloquine	C0030193	pain	1	[P11511]	DRUG	0.018943768
M03BX08	cyclobenzaprine	C0038454	cerebrovascular accident	3	[P05362, P28223, P07550]	DRUG_AND_METABOLITE	0.133832308
R06AD02	promethazine	C0015230	rash	2	[P28223, P08908]	DRUG	0.122666179
P01BC02	mefloquine	C0023530	leukopenia	1	[P08183]	DRUG	0.044087091
M03CA01	dantrolene	C0024299	lymphoma	1	[P21817]	DRUG	0.100990451
N03AX11	topiramate	C0004134	ataxia	1	[P35498]	DRUG	0.07425294
N07XX02	riluzole	C0005967	bone neoplasm	4	[P05177, O15554, Q9UNQ0, P04798]	DRUG	0.136736071
N06AB06	sertraline	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.039009407
N06AF03	phenelzine	C0024141	lupus	1	[P04179]	METABOLITE	0.233518101
N04BC05	pramipexole	C0085694	cholecystitis chronic	1	[P31645]	DRUG	0.13520144
G03AC06	medroxyprogesterone	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.059505271
N04BC05	pramipexole	C0085649	peripheral edema	1	[P08588]	DRUG	0.047831182
N06DA02	donepezil	C0010709	cyst	2	[P49682, P05067]	DRUG	0.304877745
C01EB03	indomethacin	C0009951	convulsions	6	[P35498, P08183, Q99250, P33527, Q9NY46, P35354]	DRUG_AND_METABOLITE	0.001095504
G04BE08	tadalafil	C0010054	coronary artery disease	2	[P08684, Q08499]	DRUG	0.093159412
N04AC01	benztropine	C0039231	tachycardia	1	[P08588]	DRUG_AND_METABOLITE	0.03201379
N06AX11	mirtazapine	C0027051	myocardial infarction	4	[P11712, P31645, P05177, P18089]	DRUG	0.050945221
S01ED02	betaxolol	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.000645029
A02BB01	misoprostol	C0027051	myocardial infarction	2	[P43116, Q07869]	METABOLITE	0.064837266
N06AB03	fluoxetine	C0015695	liver fatty	1	[P05181]	DRUG	0.145448571
J04BA02	dapsone	C0030305	pancreatitis	3	[Q99895, P05181, P35354]	DRUG	0.003610369
C01DA02	nitroglycerin	C0018799	heart disease	1	[P16066]	DRUG	0.222481775
M01AB02	sulindac	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.001702954
N01AH01	fentanyl	C0009951	convulsions	1	[P08183]	DRUG	0.146124054
N06AA10	nortriptyline	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.005979133
A07EC04	balsalazide	C0013390	dysmenorrhea	1	[P35354]	DRUG_AND_METABOLITE	0.012309865
N05AE04	ziprasidone	C0007785	cerebral infarction	1	[P21731]	DRUG	0.15591646
A07EC04	balsalazide	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.020619485
N05AB02	fluphenazine	C1527304	allergic reaction	2	[P41595, P35367]	DRUG_AND_METABOLITE	0.021169216
N04BC02	pergolide	C0021311	infection	1	[P07550]	DRUG	0.451527115
N04BX01	tolcapone	C0022408	arthrosis	1	[P27487]	METABOLITE	0.094952502
A08AA10	sibutramine	C0013595	eczema	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.010306771
N06AB03	fluoxetine	C0020473	hyperlipidemia	1	[P15121]	METABOLITE	0.192471511
N06AA01	desipramine	C0027051	myocardial infarction	11	[P02768, P13945, P05362, P07550, P11712, P33261, P31645, P23219, P05177, P08588, P18089]	DRUG	0.000905071
A03FA02	cisapride	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.002318647
A03FA02	cisapride	C0039239	sinus tachycardia	2	[P07550, P08588]	DRUG	0.002318647
N05AA01	chlorpromazine	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.107647419
G03AC06	medroxyprogesterone	C0015672	fatigue	1	[P04150]	DRUG_AND_METABOLITE	0.021841092
C01BC03	propafenone	C0011849	diabetes mellitus	4	[P11712, O15245, P08684, P10632]	DRUG	0.003209136
L01AX03	temozolomide	C0022116	ischemia	1	[P05181]	METABOLITE	0.060419655
C07AG02	carvedilol	C0019080	hemorrhage	2	[P15692, P11712]	DRUG	0.009790798
C07AG02	carvedilol	C0022116	ischemia	2	[P05181, Q14524]	DRUG	0.022579198
N04BC05	pramipexole	C0025202	melanoma	2	[P20309, P25021]	DRUG	0.426566789
N02BA11	diflunisal	C0015672	fatigue	1	[P35354]	DRUG	0.028343005
M01AC06	meloxicam	C0002736	als	1	[P35354]	DRUG_AND_METABOLITE	0.081761141
N03AX12	gabapentin	C0678222	breast cancer	2	[Q01650, P54687]	DRUG_AND_METABOLITE	0.372392985
L04AA06	mycophenolic acid	C0041912	upper respiratory tract infection	1	[P37231]	DRUG_AND_METABOLITE	0.168674498
N01BB09	ropivacaine	C0035455	rhinitis	1	[P00533]	METABOLITE	0.088917357
N06AA04	clomipramine	C0027051	myocardial infarction	12	[P02768, P21554, P13945, P06276, P07550, P11712, P33261, P31645, P05177, P08588, P18089, Q12791]	METABOLITE	0.008236987
A07EA06	budesonide	C0029456	osteoporosis	5	[P11511, P05093, P08684, P04798, P10275]	METABOLITE	0.000256201
C10AA02	lovastatin	C0032533	polymyalgia rheumatica	1	[P05362]	DRUG	0.092611701
A04AA02	granisetron	C0004093	asthenia	1	[P28223]	DRUG	0.037086334
C01EB03	indomethacin	C0027726	nephrotic syndrome	5	[P15121, P37231, P35354, P02768, P10145]	DRUG	0.010494151
J01FA10	azithromycin	C0027726	nephrotic syndrome	1	[P00813]	DRUG_AND_METABOLITE	0.182889671
N07AA02	pyridostigmine	C0004096	asthma	2	[P11229, P20309]	DRUG	0.033872366
N05AB02	fluphenazine	C0020538	hypertension	5	[P35348, P21728, P28223, P08913, P18089]	DRUG	0.021406141
N05AX12	aripiprazole	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG_AND_METABOLITE	0.160121456
A10BB09	gliclazide	C0019080	hemorrhage	2	[P15692, P11712]	DRUG	0.000832892
J02AC02	itraconazole	C0001175	acquired immunodeficiency syndrome	3	[P20815, P20813, P08684]	DRUG_AND_METABOLITE	0.002107102
A01AC01	triamcinolone	C0010481	Cushing syndrome	1	[P04150]	DRUG	0.017775363
N06AB03	fluoxetine	C0020550	hyperthyroidism	1	[P08183]	DRUG	0.145448571
N06AB03	fluoxetine	C0020538	hypertension	11	[P20815, Q08499, P35348, P21728, P31645, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG	2.1542E-05
N06AB03	fluoxetine	C0020542	pulmonary hypertension	1	[P31645]	DRUG_AND_METABOLITE	0.148031193
M01AH03	valdecoxib	C0600139	prostate cancer	12	[P35354, P33527, Q16790, Q9Y5N1, P08684, P23219, P08842, P49137, P33261, P34972, P21554, P35348]	DRUG_AND_METABOLITE	0.28738475
L01XX11	estramustine	C0003123	anorexia	1	[P04278]	METABOLITE	0.117078755
C09AA04	perindopril	C0021311	infection	1	[P12821]	DRUG_AND_METABOLITE	0.155436654
J05AE01	saquinavir	C0002103	allergic rhinitis	1	[P11712]	DRUG	0.114691244
N06AA04	clomipramine	C0022408	arthrosis	1	[Q9H3N8]	METABOLITE	0.386521894
C09CA06	candesartan	C0041948	uremia	1	[P30556]	DRUG_AND_METABOLITE	0.085154973
C03CA01	furosemide	C0030305	pancreatitis	2	[Q99895, P00918]	DRUG_AND_METABOLITE	0.040568762
M01AE12	oxaprozin	C0017152	gastritis	2	[P23219, P35354]	DRUG	0.00145582
M01AH03	valdecoxib	C1527304	allergic reaction	4	[P41595, Q01959, P35367, P25021]	DRUG_AND_METABOLITE	0.000495529
N06AB03	fluoxetine	C0020569	salivary gland enlargement	1	[P20309]	DRUG_AND_METABOLITE	0.173536124
M03BX01	baclofen	C0014544	epilepsy	3	[P35498, Q99250, Q9NY46]	DRUG	0.003498752
A08AB01	orlistat	C0021311	infection	1	[P49327]	DRUG	0.311927901
C09CA06	candesartan	C0041912	upper respiratory tract infection	1	[P23219]	DRUG_AND_METABOLITE	0.248968302
C07AA06	timolol	C0018790	cardiac arrest	1	[P07550]	DRUG	0.037934867
N02AA03	hydromorphone	C0009951	convulsions	5	[P35498, P08183, Q99250, Q9NY46, P31645]	METABOLITE	0.001297825
N06AA12	doxepin	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.031085906
N05AH03	olanzapine	C0038525	subarachnoid hemorrhage	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.024248302
N06AA09	amitriptyline	C0015230	rash	6	[P07550, P28223, P08908, P31645, P17405, P04629]	DRUG	0.026766868
N05AH03	olanzapine	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.061456377
C03DB01	amiloride	C0039070	syncope	1	[P29274]	DRUG	0.049976501
C07AG02	carvedilol	C0002874	aplastic anemia	1	[P04798]	DRUG	0.121673094
C07AG02	carvedilol	C0002871	anemia	1	[P15692]	DRUG	0.095543377
J01MA01	ofloxacin	C0008031	chest pain	1	[P02768]	METABOLITE	0.01564125
H02AA02	fludrocortisone	C0085660	Aseptic necrosis	1	[P08183]	DRUG_AND_METABOLITE	0.035667691
N02CA01	dihydroergotamine	C0019348	herpes simplex	1	[P35408]	DRUG	0.187876941
N06AB04	citalopram	C0019158	hepatitis	1	[P05181]	DRUG	0.115784639
C08CA01	amlodipine	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.042436544
L02BB03	bicalutamide	C0020615	hypoglycemia	1	[P04150]	DRUG	0.026665834
N05AA01	chlorpromazine	C0039070	syncope	1	[P29274]	DRUG	0.107647419
N06AA01	desipramine	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.006452293
L02BA01	tamoxifen	C0027051	myocardial infarction	9	[P35354, P03372, P04798, P10275, Q92731, P11712, P33261, P23219, P05177]	DRUG_AND_METABOLITE	0.000176164
C10AA04	fluvastatin	C0030305	pancreatitis	1	[P04798]	DRUG_AND_METABOLITE	0.103777387
L02BG06	exemestane	C0006826	cancer	5	[P18405, P08684, P10275, P11511, Q12809]	METABOLITE	0.006596074
R06AX26	fexofenadine	C0018802	congestive heart failure	1	[Q12809]	DRUG	0.054232974
H05BX01	cinacalcet	C0003123	anorexia	1	[P31645]	DRUG	0.043076879
C10AA04	fluvastatin	C0022408	arthrosis	1	[P27487]	DRUG_AND_METABOLITE	0.103777387
N04BC04	ropinirole	C0085649	peripheral edema	1	[P08588]	DRUG	0.037128649
C09AA02	enalapril	C0034063	pulmonary edema	1	[P12821]	DRUG_AND_METABOLITE	0.015294093
A10BB09	gliclazide	C0013604	edema	1	[P15692]	DRUG	0.012425662
M01AE09	flurbiprofen	C0023530	leukopenia	4	[P16662, O60656, P22309, P08246]	DRUG	5.32947E-05
G04CA03	terazosin	C0009806	constipation	2	[P46098, P41595]	DRUG	0.00363511
N03AE01	clonazepam	C0002871	anemia	2	[P02768, P07148]	METABOLITE	0.019329788
L01XE01	imatinib	C0025323	menorrhagia	1	[P35916]	DRUG	0.046295534
P01AX06	atovaquone	C0004093	asthenia	2	[P31645, P28223]	METABOLITE	0.023338897
N06BA01	amphetamine	C0020517	hypersensitivity	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	METABOLITE	0.001214872
A02BC03	lansoprazole	C0027051	myocardial infarction	4	[P04798, P11712, P33261, P05177]	DRUG_AND_METABOLITE	0.024401265
N05AH04	quetiapine	C0015230	rash	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG	0.00348143
C03BA11	indapamide	C0011849	diabetes mellitus	1	[P51787]	DRUG_AND_METABOLITE	0.265101728
C03AA03	hydrochlorothiazide	C0030305	pancreatitis	1	[P00918]	DRUG	0.107727124
P01AB01	metronidazole	C0020538	hypertension	1	[P11712]	DRUG	0.092998912
L04AX04	lenalidomide	C0021311	infection	4	[P01375, P19838, P35354, P23219]	DRUG	0.049477114
N05AX08	risperidone	C0019080	hemorrhage	1	[P21731]	DRUG_AND_METABOLITE	0.144458057
L01XE01	imatinib	C0041912	upper respiratory tract infection	27	[P42336, P00533, P23458, P00519, Q9UBN7, Q13546, P19525, P08631, Q02156, P43405, P78362, Q96SB4, P04049, P52799, P16234, Q13153, P23219, P04629, P49771, P31749, P17252, Q14164, P28482, O43353, Q16539, P27361, Q04759]	DRUG	0.082202439
N02CC06	eletriptan	C0023530	leukopenia	1	[P08183]	DRUG	0.051010927
A07EA06	budesonide	C0022116	ischemia	2	[P35354, P05181]	METABOLITE	0.039106452
N06AB03	fluoxetine	C1527304	allergic reaction	3	[P41595, Q01959, P35367]	DRUG_AND_METABOLITE	0.004222847
A10BA02	metformin	C0003123	anorexia	1	[P27487]	DRUG	0.030193271
H02AB02	dexamethasone	C0010481	Cushing syndrome	1	[P04150]	DRUG_AND_METABOLITE	0.088258057
M01AH01	celecoxib	C0004093	asthenia	3	[P31645, P28223, P35354]	DRUG_AND_METABOLITE	0.000443312
N05AH03	olanzapine	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG_AND_METABOLITE	0.162947188
N03AF01	carbamazepine	C0003123	anorexia	3	[P28223, P28335, P14416]	DRUG	0.001540647
A10BB09	gliclazide	C0013595	eczema	1	[P15692]	DRUG	0.06589552
L04AX02	thalidomide	C0497327	dementia	6	[Q9UI32, P43003, P01375, P80404, Q13002, Q16478]	METABOLITE	0.038585711
N02AA05	oxycodone	C0024115	lung disorder	1	[P31645]	DRUG	0.144529733
A03BA01	atropine	C0009806	constipation	1	[P46098]	DRUG	0.037128649
M01AE09	flurbiprofen	C0016059	fibrosis	2	[P10145, P35354]	DRUG_AND_METABOLITE	0.073960049
C01EB03	indomethacin	C0015672	fatigue	1	[P35354]	DRUG_AND_METABOLITE	0.063064427
N02AA03	hydromorphone	C0009806	constipation	1	[P31645]	METABOLITE	0.042974428
C09AA02	enalapril	C0038454	cerebrovascular accident	1	[P12821]	DRUG_AND_METABOLITE	0.107647419
N05AX12	aripiprazole	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG_AND_METABOLITE	5.82409E-05
M01AE09	flurbiprofen	C0023518	leukocytosis	1	[P10145]	DRUG	0.027818585
M01AH02	rofecoxib	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.056501401
C08DA01	verapamil	C0041912	upper respiratory tract infection	1	[Q13936]	DRUG_AND_METABOLITE	0.495263554
N05CF02	zolpidem	C0041912	upper respiratory tract infection	1	[P23219]	DRUG	0.418974535
M01AC01	piroxicam	C0042109	urticaria	1	[P09917]	DRUG	0.027706733
N03AG06	tiagabine	C0037763	spasm	3	[P18507, P14867, P28472]	DRUG	0.00011366
N06BA09	atomoxetine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000245734
M01AB15	ketorolac	C0243026	sepsis	1	[P10145]	DRUG	0.120421585
N02CC01	sumatriptan	C0021311	infection	2	[P07550, P03372]	METABOLITE	0.453079094
A05AA02	ursodeoxycholic acid	C1458155	breast neoplasm	7	[O75469, Q92887, P52895, P11473, Q96RI1, P46721, P05181]	DRUG_AND_METABOLITE	0.053108318
A04AA01	ondansetron	C0042109	urticaria	1	[P07550]	DRUG	0.112841395
C08DB01	diltiazem	C0027051	myocardial infarction	2	[P11712, P33261]	DRUG	0.185264519
J05AE04	nelfinavir	C0149931	migraine	1	[P08684]	DRUG_AND_METABOLITE	0.064840779
D01AC08	ketoconazole	C0015230	rash	1	[P09601]	DRUG	0.277558428
N05AH02	clozapine	C0038220	status epilepticus	3	[P18507, P28472, Q9UBS5]	DRUG	0.00316216
G03AC06	medroxyprogesterone	C0020550	hyperthyroidism	1	[P08183]	DRUG_AND_METABOLITE	0.049355201
J01AA08	minocycline	C0040034	thrombocytopenia	1	[P99999]	DRUG	0.064721996
B01AC05	ticlopidine	C0004093	asthenia	1	[P35354]	DRUG_AND_METABOLITE	0.040601904
C07AG01	labetalol	C0011570	mental depression	4	[P28223, P28335, P28222, P08908]	DRUG	4.50063E-06
L04AX04	lenalidomide	C0231528	myalgia	1	[Q08499]	DRUG	0.091808164
L04AX04	lenalidomide	C0021400	Influenza	1	[P01375]	DRUG	0.062319473
P01BC02	mefloquine	C0009951	convulsions	1	[P08183]	DRUG	0.108919575
N07BA01	nicotine	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.009521978
N05AE04	ziprasidone	C0019080	hemorrhage	1	[P21731]	DRUG	0.1456393
C07AA03	pindolol	C0013604	edema	1	[P08588]	DRUG	0.034147949
N02AA05	oxycodone	C0009806	constipation	1	[P31645]	DRUG	0.019239124
C09CA01	losartan	C0004238	atrial fibrillation	1	[P12821]	DRUG	0.099143217
N03AB04	mephenytoin	C0002871	anemia	1	[P02768]	DRUG	0.146640821
J05AE01	saquinavir	C0010709	cyst	5	[P08183, Q92887, P33527, Q9UNQ0, P20815]	DRUG	0.148192871
N06BA01	amphetamine	C0020538	hypertension	13	[P35348, P07550, P14780, P21728, P31645, P28223, P11712, P23975, P08913, P18089, P08588, P11086, P55055]	METABOLITE	0.000276701
M01AE09	flurbiprofen	C0011991	diarrhea	3	[P10145, O60656, P16662]	DRUG	0.00017857
A02BC02	pantoprazole	C0010709	cyst	5	[P05177, P08183, Q9UNQ0, Q16678, P04798]	METABOLITE	0.224520252
L01XX05	hydroxyurea	C0024141	lupus	1	[P14780]	METABOLITE	0.11212514
M01AE01	ibuprofen	C0021311	infection	6	[P10145, Q9BPW9, P35354, P23219, P27695, P09917]	DRUG	0.306627599
A02BC01	omeprazole	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.072104339
A04AD12	aprepitant	C0027051	myocardial infarction	3	[P11712, P33261, P05177]	DRUG_AND_METABOLITE	0.005446139
M01AH03	valdecoxib	C0029456	osteoporosis	2	[P08684, P34972]	DRUG_AND_METABOLITE	0.082956716
L04AX04	lenalidomide	C0038454	cerebrovascular accident	3	[Q08499, P01375, P35354]	DRUG	0.009092759
N06AA01	desipramine	C0014549	grand mal	2	[Q99250, P35498]	DRUG	0.029823411
C09AA03	lisinopril	C0023530	leukopenia	1	[P08183]	DRUG	0.023338897
M01AB02	sulindac	C0027726	nephrotic syndrome	4	[P15121, P37231, P35354, P02768]	DRUG	0.002642872
N02AA01	morphine	C0009806	constipation	1	[P31645]	METABOLITE	0.042974428
A10BB09	gliclazide	C0007097	carcinoma	1	[P15692]	DRUG	0.393933043
A02BC01	omeprazole	C0018524	hallucinations	2	[P08183, P50993]	DRUG_AND_METABOLITE	0.026968781
N06AA04	clomipramine	C0039070	syncope	1	[P29274]	METABOLITE	0.093425362
L04AA13	leflunomide	C0022408	arthrosis	1	[Q9UM07]	DRUG	0.094952502
N06AA12	doxepin	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.012957975
R03DA04	theophylline	C0242184	hypoxia	5	[P29275, P47989, Q14432, P00813, P01375]	METABOLITE	0.096593322
A02BC02	pantoprazole	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.111855571
M01AG01	mefenamic acid	C0009951	convulsions	1	[P35354]	DRUG	0.102909805
N04BC04	ropinirole	C0018799	heart disease	4	[P08588, P07550, Q13639, P41595]	DRUG	0.014022221
N04BC04	ropinirole	C0018790	cardiac arrest	2	[P18089, P07550]	DRUG	0.007572786
M01AH01	celecoxib	C0020517	hypersensitivity	4	[P41595, Q01959, P35367, P25021]	DRUG	0.001609914
N05AX08	risperidone	C0027947	neutropenia	1	[P08183]	DRUG	0.115784639
R06AD02	promethazine	C0015672	fatigue	1	[P28223]	DRUG_AND_METABOLITE	0.057302129
M01AH01	celecoxib	C0020538	hypertension	10	[P35348, P21728, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089, P18054]	DRUG	0.000256201
C03DB01	amiloride	C0085584	encephalopathy	2	[P14867, P35372]	DRUG	0.036361911
N05AA01	chlorpromazine	C0010200	cough	1	[Q8NER1]	DRUG	0.057987175
C07AB04	acebutolol	C0015230	rash	2	[P07550, P08908]	DRUG	0.015405718
N04BC04	ropinirole	C0018824	valvular heart disease	2	[P08588, P07550]	DRUG	0.083028863
G03CA03	estradiol	C0600327	toxic shock syndrome	1	[P03372]	DRUG_AND_METABOLITE	0.499995859
C07AB04	acebutolol	C0042109	urticaria	1	[P07550]	DRUG	0.027706733
L04AX01	azathioprine	C0026986	myelodysplastic syndrome	1	[P27361]	METABOLITE	0.323386507
L04AX02	thalidomide	C0002962	angina pectoris	1	[P01375]	DRUG	0.19833143
N04BC04	ropinirole	C0021311	infection	1	[P07550]	DRUG	0.451527115
B01AC04	clopidogrel	C0030920	peptic ulcer	1	[P33261]	DRUG	0.039426707
C01BA01	quinidine	C0011991	diarrhea	1	[Q92887]	DRUG	0.075243023
N06AB04	citalopram	C1527304	allergic reaction	2	[Q01959, P35367]	DRUG	0.012643911
N03AG06	tiagabine	C0020538	hypertension	1	[P35348]	DRUG	0.340654239
N04BC04	ropinirole	C0018801	heart failure	1	[P07550]	DRUG	0.123348216
L02AB01	megestrol	C0011849	diabetes mellitus	3	[P11712, P08684, P10632]	DRUG	0.005396749
N05BE01	buspirone	C0013384	dyskinesia	4	[P35498, P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.00216838
R03DC01	zafirlukast	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.095009391
N06AB03	fluoxetine	C0027813	neuritis	1	[P08183]	DRUG	0.117289663
G03CA03	estradiol	C1458155	breast neoplasm	30	[Q9UNQ0, P04798, Q16678, P08684, P03372, P21964, Q99527, P08183, Q92731, P04278, O75469, O15438, Q92887, P33527, P30536, P50225, P22309, O00591, P14061, P08842, P46721, P05181, P05177, Q9NPD5, P10275, P20813, P11474, P32238, P32239, P20815]	DRUG_AND_METABOLITE	0.037653032
L01XE01	imatinib	C0231528	myalgia	3	[Q09013, P17252, P24723]	DRUG	0.204501517
A02BC03	lansoprazole	C0020433	bilirubinemia	1	[Q9Y6L6]	METABOLITE	0.050945221
G04BE07	apomorphine	C0013604	edema	1	[P08588]	DRUG	0.049333365
J02AC03	voriconazole	C0020538	hypertension	3	[P20815, P11712, P31513]	DRUG	0.011557989
C01BD01	amiodarone	C0442874	neuropathy	1	[P08183]	DRUG	0.108816906
H02AA02	fludrocortisone	C0018802	congestive heart failure	1	[P08235]	DRUG_AND_METABOLITE	0.070407486
C07AG02	carvedilol	C0085610	sinus bradycardia	1	[Q14524]	DRUG	0.018096702
N05AH03	olanzapine	C0149931	migraine	4	[P28223, P21917, P31645, P28335]	DRUG_AND_METABOLITE	0.001106422
A16AA04	cysteamine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	2.61246E-06
C07AG02	carvedilol	C0085649	peripheral edema	2	[P15692, P08588]	DRUG_AND_METABOLITE	0.001365729
N06AA11	protriptyline	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.004408314
D07AC13	mometasone	C0043144	wheezing	1	[P04150]	METABOLITE	0.077274451
R03DC03	montelukast	C0019158	hepatitis	2	[P23219, P11509]	DRUG_AND_METABOLITE	0.005127252
N04BC05	pramipexole	C0021311	infection	1	[P07550]	DRUG	0.486989154
N07BB01	disulfiram	C0011615	atopic dermatitis	1	[P00352]	DRUG	0.171578823
N03AB04	mephenytoin	C0027720	nephrosis	1	[P02768]	DRUG	0.153656891
N02AD01	pentazocine	C0011991	diarrhea	1	[P46098]	DRUG	0.040283843
N02AA01	morphine	C0009951	convulsions	5	[P35498, P08183, Q99250, Q9NY46, P31645]	METABOLITE	0.001297825
N04BD01	selegiline	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.00486818
N06AA11	protriptyline	C0018681	headache	1	[P05362]	DRUG	0.09082074
N05AX08	risperidone	C0032000	pituitary adenomas	2	[P08183, P14416]	DRUG_AND_METABOLITE	0.095416353
C10AA05	atorvastatin	C0022346	jaundice	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.020490582
N06AX16	venlafaxine	C0497327	dementia	3	[P08908, P21397, P31645]	DRUG_AND_METABOLITE	0.151656571
N05AH03	olanzapine	C0149779	somatization	2	[P35462, P28223]	DRUG_AND_METABOLITE	0.027162705
H02AA02	fludrocortisone	C0026848	myopathy	1	[P10275]	DRUG_AND_METABOLITE	0.087842605
C07AA06	timolol	C0018801	heart failure	1	[P07550]	DRUG	0.070407486
N05AX08	risperidone	C0085649	peripheral edema	1	[P08588]	DRUG_AND_METABOLITE	0.062610213
C07AA06	timolol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.070407486
N04BD01	selegiline	C0497327	dementia	3	[P08908, P21397, P31645]	METABOLITE	0.054135291
C07AG02	carvedilol	C0031099	periodontitis	1	[P04798]	DRUG	0.068584098
M01AE09	flurbiprofen	C0009951	convulsions	1	[P35354]	DRUG_AND_METABOLITE	0.209262313
N06BA07	modafinil	C0020538	hypertension	5	[P20815, P35348, P11712, P23975, P21964]	DRUG	0.000221093
C09CA06	candesartan	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.039903358
M01AB05	diclofenac	C0021400	Influenza	1	[P10145]	DRUG_AND_METABOLITE	0.129936284
N06BA07	modafinil	C0020517	hypersensitivity	1	[Q01959]	DRUG	0.05886078
G03DA04	progesterone	C0006145	breast disorders	1	[P03372]	DRUG_AND_METABOLITE	0.094013826
N06AX21	duloxetine	C0002871	anemia	1	[P02768]	DRUG	0.266243108
N06AB03	fluoxetine	C0836924	thrombocythemia	1	[P10275]	METABOLITE	0.096973815
C01BC03	propafenone	C0178428	sinus arrest	1	[Q14524]	DRUG	0.021600815
N05CA06	secobarbital	C0018524	hallucinations	4	[P36544, P35498, Q99250, Q9NY46]	DRUG	6.35658E-05
M01AE02	naproxen	C0030305	pancreatitis	2	[P07858, P35354]	DRUG	0.106657016
R03DA04	theophylline	C0036572	seizures	3	[Q99250, P35498, P48029]	DRUG	0.004054035
L02BB03	bicalutamide	C0020538	hypertension	2	[P03372, P04150]	DRUG	0.018841569
N06AX06	nefazodone	C0011991	diarrhea	2	[P46098, A5X5Y0]	METABOLITE	0.008464182
C09AA02	enalapril	C0085580	essential hypertension	3	[Q9BYF1, P00797, P12821]	DRUG_AND_METABOLITE	0.010917197
N05CD02	nitrazepam	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000329338
N06AB06	sertraline	C0042024	urinary incontinence	2	[P08172, P28223]	DRUG_AND_METABOLITE	0.005393105
A05AA02	ursodeoxycholic acid	C0023530	leukopenia	1	[Q92887]	DRUG_AND_METABOLITE	0.053194386
M01AB05	diclofenac	C0037287	skin nodule	3	[P21554, P35354, P34972]	DRUG	0.012596519
C09CA06	candesartan	C0019159	hepatitis infectious	1	[P23219]	DRUG_AND_METABOLITE	0.056501401
C09CA06	candesartan	C0019158	hepatitis	1	[P23219]	DRUG_AND_METABOLITE	0.056501401
M01AB05	diclofenac	C0021311	infection	3	[P10145, P35354, P23219]	DRUG_AND_METABOLITE	0.429168109
N06AA21	maprotiline	C0015230	rash	2	[P28223, P31645]	DRUG_AND_METABOLITE	0.049355201
N05AH03	olanzapine	C0034065	pulmonary embolism	1	[P02768]	DRUG	0.071262911
C01EB03	indomethacin	C0023530	leukopenia	4	[Q92887, O60656, P22309, P08183]	DRUG	0.000356248
J05AB09	famciclovir	C0149931	migraine	1	[P08684]	DRUG	0.037810863
C04AD03	pentoxifylline	C0023418	leukemia	5	[P01375, Q08499, Q07343, P27815, P21589]	DRUG	0.003584806
N06AB03	fluoxetine	C0035078	renal failure	1	[P08183]	DRUG	0.171121365
A02BC03	lansoprazole	C0020517	hypersensitivity	1	[P25021]	DRUG_AND_METABOLITE	0.096195732
N05AB02	fluphenazine	C0004096	asthma	1	[P11229]	DRUG	0.394694013
L01XE03	erlotinib	C0021311	infection	25	[P42336, P00533, P23458, P00519, Q13546, P19525, P08631, Q02156, P43405, P78362, Q96SB4, P04049, P16234, Q13153, P04629, P49771, P31749, Q14164, P28482, O43353, Q16539, P27361, Q04759, P36897, P37173]	DRUG_AND_METABOLITE	0.128073342
N03AG04	vigabatrin	C0038220	status epilepticus	1	[Q9UBS5]	DRUG	0.010569187
C02AC01	clonidine	C0038454	cerebrovascular accident	1	[P28223]	DRUG	0.207011871
A02BC03	lansoprazole	C0020538	hypertension	4	[P05026, P05023, Q02928, P11712]	DRUG_AND_METABOLITE	0.018230975
N06AA02	imipramine	C0040822	tremor	1	[Q14643]	METABOLITE	0.073814713
L04AX04	lenalidomide	C0029456	osteoporosis	3	[O14788, P01375, P04798]	DRUG	0.003333335
C08CA05	nifedipine	C0004134	ataxia	3	[O00555, Q09470, P35498]	DRUG	0.005743402
M01AE01	ibuprofen	C0020456	hyperglycemia	3	[P35354, P10145, P07148]	DRUG	0.021310773
N06AA02	imipramine	C0009951	convulsions	11	[P35498, Q9UBS5, P08183, P36544, Q99250, P04156, Q9NY46, P30874, P08908, P31645, P29475]	METABOLITE	0.000107249
L01BB02	mercaptopurine	C0243026	sepsis	2	[P47989, P11217]	METABOLITE	0.017396684
G04BE08	tadalafil	C0007859	neck pain	1	[Q08499]	DRUG	0.022436068
J05AF04	stavudine	C0019158	hepatitis	2	[P11509, P02768]	METABOLITE	0.024907442
J05AF04	stavudine	C0019163	hepatitis B	1	[P11509]	METABOLITE	0.173378029
N07BB04	naltrexone	C0149931	migraine	1	[P31645]	DRUG	0.054940301
J05AE01	saquinavir	C0018524	hallucinations	2	[P08183, P33527]	DRUG	0.017354004
N06DA03	rivastigmine	C0009319	colitis	1	[P31645]	DRUG	0.09004742
L01BA01	methotrexate	C0011849	diabetes mellitus	2	[P42898, P02768]	DRUG	0.17865788
N06AX21	duloxetine	C0040822	tremor	1	[Q14643]	DRUG	0.064097201
N03AB02	phenytoin	C0002871	anemia	1	[P02768]	DRUG	0.146640821
N01BA02	procaine	C0001122	acidosis	1	[Q16790]	METABOLITE	0.085892844
N05AX08	risperidone	C0036337	schizoaffective disorder	23	[P35462, P28223, P36544, P32238, P11229, P08912, P21917, P14416, P28335, P21728, P28222, P08908, P20815, P31645, Q01959, P25103, P50406, P35367, P35372, P21554, P17787, P08173, P08183]	DRUG	0
C03DB01	amiloride	C0035078	renal failure	2	[Q16853, P29274]	DRUG	0.040175542
J01MA01	ofloxacin	C0004096	asthma	1	[P33527]	DRUG	0.257146572
M01AH03	valdecoxib	C0149931	migraine	4	[P28223, P31645, P08684, P28335]	DRUG_AND_METABOLITE	0.000723628
P02CA03	albendazole	C0027947	neutropenia	1	[P08183]	DRUG	0.037092814
C02CA04	doxazosin	C0009951	convulsions	2	[P08183, P08908]	METABOLITE	0.045203907
N06AA06	trimipramine	C0012833	dizziness	1	[P29274]	METABOLITE	0.053008495
N06AA11	protriptyline	C0023530	leukopenia	1	[P08183]	DRUG	0.149189442
C07AG02	carvedilol	C0151744	myocardial ischemia	4	[P07550, P08588, P16860, Q12809]	DRUG	7.29447E-05
N06AB04	citalopram	C0015230	rash	3	[P28223, P08908, P31645]	DRUG	0.019839873
N06AB06	sertraline	C0003123	anorexia	6	[P28223, P28335, P21397, P31645, P23975, P14416]	DRUG_AND_METABOLITE	4.52444E-07
R03AC12	salmeterol	C0152029	sinus congestion	1	[P08588]	DRUG	0.054359067
A04AA02	granisetron	C0015230	rash	2	[P28223, P08908]	DRUG_AND_METABOLITE	0.054555669
D01AC08	ketoconazole	C0042109	urticaria	1	[P09917]	DRUG	0.07797371
N04AC01	benztropine	C1527304	allergic reaction	2	[Q01959, P35367]	DRUG_AND_METABOLITE	0.011432473
J01DC04	cefaclor	C0008031	chest pain	1	[P02768]	DRUG	0.010207101
N05AE04	ziprasidone	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.170818616
C08CA05	nifedipine	C0004093	asthenia	1	[P28223]	DRUG	0.061564341
A02BC01	omeprazole	C0041912	upper respiratory tract infection	1	[P08575]	DRUG_AND_METABOLITE	0.451518059
J05AE07	fosamprenavir	C0011849	diabetes mellitus	3	[P11712, P08684, P10632]	METABOLITE	0.013399503
C08CA04	nicardipine	C0012833	dizziness	1	[P29274]	DRUG	0.023338897
N06AB06	sertraline	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.056653613
C07AG01	labetalol	C0015672	fatigue	1	[P28223]	DRUG	0.023218364
C01BB02	mexiletine	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.02477419
N05AX08	risperidone	C0021311	infection	1	[P07550]	DRUG_AND_METABOLITE	0.499995859
M01AH02	rofecoxib	C0027051	myocardial infarction	9	[P35354, P21554, P43116, P11712, P31645, P23219, P05177, P18089, P15502]	DRUG_AND_METABOLITE	0.000861554
J01FA09	clarithromycin	C0027651	tumor	10	[P08684, P08183, P33527, P46721, P05177, P20815, P25025, Q12809, P27635, P33261]	DRUG_AND_METABOLITE	0.04898487
A05AA02	ursodeoxycholic acid	C0024115	lung disorder	2	[P11473, P05181]	DRUG_AND_METABOLITE	0.054555669
N03AX16	pregabalin	C0575090	Balance disorder	2	[P80404, O00555]	DRUG	0.002227497
C04AD03	pentoxifylline	C0019158	hepatitis	1	[P01375]	DRUG_AND_METABOLITE	0.071478293
N04BC02	pergolide	C0033975	psychosis	6	[P35462, P28223, P21917, Q13639, P28222, P08908]	DRUG_AND_METABOLITE	1.16771E-06
A07EA06	budesonide	C0021311	infection	6	[P35228, P05113, P35354, P23219, P09917, P04150]	DRUG_AND_METABOLITE	0.049485821
C08CA05	nifedipine	C0004238	atrial fibrillation	1	[P22460]	DRUG	0.159190934
N06AX11	mirtazapine	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.003713939
N06AX11	mirtazapine	C0004096	asthma	1	[P11229]	DRUG	0.369658864
N05AX08	risperidone	C0036202	sarcoidosis	1	[P25103]	DRUG_AND_METABOLITE	0.200077734
N04BC05	pramipexole	C0497327	dementia	2	[P08908, P31645]	DRUG	0.136165481
A07EC01	sulfasalazine	C0015230	rash	2	[P37231, P09211]	DRUG	0.077843187
N06AB05	paroxetine	C0018944	hematoma	1	[P11712]	DRUG	0.090729349
N05AA01	chlorpromazine	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.249014435
C01BA02	procainamide	C0018790	cardiac arrest	2	[Q14524, Q12809]	DRUG_AND_METABOLITE	0.003335579
N06AA01	desipramine	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.011041651
N07AX01	pilocarpine	C0019158	hepatitis	2	[P05181, P11509]	DRUG	0.004222847
C07AB07	bisoprolol	C0041912	upper respiratory tract infection	1	[P07550]	DRUG_AND_METABOLITE	0.168674498
R03DC03	montelukast	C0015230	rash	1	[Q9Y271]	DRUG_AND_METABOLITE	0.100741343
N06AB06	sertraline	C0039231	tachycardia	1	[P08588]	DRUG	0.039009407
L01BB02	mercaptopurine	C0740394	hyperuricemia	1	[P00492]	DRUG_AND_METABOLITE	0.024082184
N06AA09	amitriptyline	C0003123	anorexia	9	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416, Q16620]	DRUG	1.48976E-07
N03AB04	mephenytoin	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.021138685
J05AF03	zalcitabine	C0011603	dermatitis	2	[P26358, P81605]	METABOLITE	0.119032795
N03AX16	pregabalin	C0040136	thyroid neoplasia	1	[Q01650]	DRUG	0.409252223
J02AC03	voriconazole	C0029456	osteoporosis	1	[P08684]	DRUG	0.081233454
C02KX01	bosentan	C0027051	myocardial infarction	1	[P11712]	DRUG_AND_METABOLITE	0.117247144
C10AB05	fenofibrate	C0013595	eczema	4	[P37231, Q9Y5Y4, Q13258, Q07869]	DRUG_AND_METABOLITE	0.000230554
L04AX02	thalidomide	C0007642	cellulitis	2	[Q07343, P01375]	DRUG	0.187544957
N02CC06	eletriptan	C0018524	hallucinations	1	[P08183]	DRUG	0.073232497
N04BD01	selegiline	C0031212	personality disorder	2	[P21397, P31645]	METABOLITE	0.001090957
J05AG01	nevirapine	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.089912296
N04BD01	selegiline	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.067909151
N05AX08	risperidone	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	7.96128E-05
A02BC04	rabeprazole	C0162316	iron deficiency anemia	1	[P02768]	DRUG_AND_METABOLITE	0.153216013
M01AX01	nabumetone	C0030920	peptic ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.001725208
C09CA04	irbesartan	C0018801	heart failure	3	[P25101, P30556, P50052]	DRUG_AND_METABOLITE	0.000516726
G03DA04	progesterone	C0020517	hypersensitivity	1	[P35367]	METABOLITE	0.238543872
M01AH03	valdecoxib	C0032227	pleural effusion	1	[Q16790]	DRUG_AND_METABOLITE	0.080872353
N02AA03	hydromorphone	C0152128	drug withdrawal	1	[P14416]	DRUG_AND_METABOLITE	0.018505915
G03DA04	progesterone	C0020565	breast enlargement	3	[P11511, P03372, P08235]	DRUG_AND_METABOLITE	0.029823411
C04AD03	pentoxifylline	C0012833	dizziness	1	[P29274]	DRUG_AND_METABOLITE	0.012309865
M01AB02	sulindac	C0030920	peptic ulcer	3	[P35354, P37231, P23219]	DRUG_AND_METABOLITE	0.000588768
N06AA04	clomipramine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.012781928
R03DC01	zafirlukast	C0021311	infection	3	[P07550, P23219, P37231]	METABOLITE	0.40816802
G03DA04	progesterone	C0020538	hypertension	17	[P05026, P20815, P35348, P03372, P21728, P05023, O15244, Q02928, P08235, P28223, P11511, P11712, P08913, P08588, Q92731, P04150, P19793]	DRUG_AND_METABOLITE	1.19504E-06
B01AC04	clopidogrel	C0023418	leukemia	1	[P20815]	DRUG	0.233518101
M01AB15	ketorolac	C0025289	meningitis	1	[P10145]	DRUG	0.040601904
G03AC06	medroxyprogesterone	C0032584	polyps	5	[P08183, P06401, P03372, P08235, P10275]	METABOLITE	0.019239124
M04AA01	allopurinol	C0231218	malaise	1	[Q08499]	METABOLITE	0.041156839
C10AA05	atorvastatin	C0232726	tenesmus	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.08498899
N06AX06	nefazodone	C0004096	asthma	1	[P07550]	METABOLITE	0.402200693
J01MA06	norfloxacin	C0027051	myocardial infarction	2	[P04798, P05177]	DRUG	0.085289777
N06AX06	nefazodone	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.005013788
M01AH03	valdecoxib	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.194818503
M01AC06	meloxicam	C0015672	fatigue	1	[P35354]	DRUG_AND_METABOLITE	0.020490582
N05AX12	aripiprazole	C0022408	arthrosis	1	[Q9H3N8]	DRUG_AND_METABOLITE	0.27335841
A10BB02	chlorpropamide	C0023530	leukopenia	1	[P08183]	DRUG	0.091808164
C09CA04	irbesartan	C0018834	heartburn	1	[P23219]	DRUG_AND_METABOLITE	0.019687894
N06DX01	memantine	C0027051	myocardial infarction	2	[P06276, P33261]	DRUG	0.11032208
D05BB02	acitretin	C0037287	skin nodule	1	[P35354]	METABOLITE	0.099143217
G02CB01	bromocriptine	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.007907224
N03AG01	valproic acid	C0027651	tumor	18	[P08684, P13726, O00591, P05177, P20813, Q13547, Q9UBN7, P56524, P20815, P10632, P23219, Q92769, O15379, P11509, Q8WUI4, P53985, P14550, P33261]	DRUG	0.26135891
H02AB02	dexamethasone	C0520474	osteonecrosis	1	[P08183]	DRUG_AND_METABOLITE	0.075667737
L02BG03	anastrozole	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.042475697
M01AB15	ketorolac	C0025290	aseptic meningitis	1	[P10145]	DRUG	0.031878908
C01BA01	quinidine	C0042510	ventricular fibrillation	1	[Q14524]	DRUG	0.022243733
L04AX02	thalidomide	C0003123	anorexia	2	[P14416, P01375]	DRUG	0.079052183
N06AX16	venlafaxine	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.056083759
L04AX02	thalidomide	C0033860	psoriasis	4	[P01375, P19838, P04798, Q05586]	METABOLITE	0.082956716
M01AB05	diclofenac	C0003850	arteriosclerosis	8	[P08684, P35354, P10145, P02768, P21554, P04798, P11712, P33261]	DRUG_AND_METABOLITE	0.010478454
C02CA04	doxazosin	C0149931	migraine	1	[P28223]	METABOLITE	0.075236175
L02BB03	bicalutamide	C0007097	carcinoma	4	[P03372, P06401, P10275, P08684]	DRUG	0.023352592
J01FA09	clarithromycin	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.048334546
M01AB05	diclofenac	C0003864	arthritis	1	[P25024]	DRUG	0.264492863
J02AC01	fluconazole	C0020443	hypercholesterolemia	1	[P09601]	DRUG	0.047831182
N06AB05	paroxetine	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.028123725
G03BA03	testosterone	C0020443	hypercholesterolemia	1	[Q9Y6L6]	METABOLITE	0.191956862
B02AA02	tranexamic acid	C0011991	diarrhea	1	[O60656]	METABOLITE	0.078956694
A07EC04	balsalazide	C0021311	infection	7	[P47989, P35354, P23219, O15111, P37231, P09917, Q07820]	METABOLITE	0.000112498
M01AH03	valdecoxib	C0018824	valvular heart disease	4	[P23219, P31645, P35354, P11712]	DRUG_AND_METABOLITE	0.031289625
C01EB03	indomethacin	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.071241753
J01AA07	tetracycline	C0024141	lupus	1	[Q9H244]	DRUG_AND_METABOLITE	0.226009783
N06AB03	fluoxetine	C0152128	drug withdrawal	1	[P14416]	DRUG_AND_METABOLITE	0.022963468
C09CA01	losartan	C0004093	asthenia	1	[P12821]	DRUG	0.039806384
G03BA03	testosterone	C0020473	hyperlipidemia	1	[P12104]	METABOLITE	0.275495733
M03BX08	cyclobenzaprine	C0009951	convulsions	10	[P35498, Q9UBS5, P08183, P36544, Q99250, P04156, Q9NY46, P30874, P08908, P31645]	DRUG_AND_METABOLITE	6.22083E-05
N04BD01	selegiline	C0011849	diabetes mellitus	4	[P11712, P08684, P18089, P10632]	DRUG	0.052669112
L02BG06	exemestane	C0030193	pain	1	[P11511]	DRUG	0.012792437
J05AE03	ritonavir	C0020538	hypertension	2	[P20815, P11712]	DRUG	0.099373048
C01BA03	disopyramide	C0178428	sinus arrest	1	[Q14524]	DRUG	0.020619485
C09AA04	perindopril	C0013404	dyspnea	1	[P12821]	DRUG_AND_METABOLITE	0.017596968
P01AX06	atovaquone	C1527304	allergic reaction	6	[P42898, Q01959, P50135, P35367, P25021, Q9H3N8]	METABOLITE	0.000176961
S01AA14	penicillin G	C0039231	tachycardia	1	[Q14524]	DRUG	0.050504261
N02AX02	tramadol	C0003123	anorexia	4	[P28335, P41143, P31645, P23975]	DRUG_AND_METABOLITE	8.36282E-06
M01AH01	celecoxib	C0017152	gastritis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.038001816
N07XX02	riluzole	C0006384	bundle branch block	1	[Q14524]	DRUG	0.006405429
M01AE09	flurbiprofen	C0022408	arthrosis	3	[P25025, P25024, P07858]	DRUG	0.009279632
N06AF03	phenelzine	C0009951	convulsions	1	[P31645]	DRUG	0.168674498
N05AB06	trifluoperazine	C0004096	asthma	12	[P07550, P09917, P05362, P47989, P35354, P23219, P43115, P29475, P11229, P29274, P20309, Q14643]	DRUG	0.01266617
M01AH02	rofecoxib	C0006826	cancer	11	[P35354, P33527, P16050, P10632, Q9Y5N1, P08684, P43116, P23219, P05177, P23975, P09917]	DRUG_AND_METABOLITE	0.319129711
C08CA05	nifedipine	C0043144	wheezing	1	[P29274]	DRUG	0.426935507
N02CC01	sumatriptan	C0040046	thrombophlebitis	2	[P03372, Q92731]	METABOLITE	0.04063245
N05AH03	olanzapine	C0085584	encephalopathy	3	[P14867, P18505, P18507]	DRUG_AND_METABOLITE	0.013699578
N05BE01	buspirone	C0004134	ataxia	1	[P35498]	DRUG	0.17352585
N04BC04	ropinirole	C0013595	eczema	3	[P07550, P28223, P08908]	DRUG	0.018896001
N02AA01	morphine	C0023530	leukopenia	2	[O60656, P08183]	DRUG_AND_METABOLITE	0.016499221
N02CC01	sumatriptan	C0003860	arteritis	1	[Q92731]	METABOLITE	0.093864358
J05AF03	zalcitabine	C0011849	diabetes mellitus	2	[P11712, P08684]	DRUG	0.16144089
G03BA03	testosterone	C0020538	hypertension	8	[P20815, P03372, O15244, P11511, P11712, Q12791, Q92731, P19793]	METABOLITE	0.020490582
N06AB05	paroxetine	C0038454	cerebrovascular accident	1	[P28223]	DRUG	0.242871133
G04BE03	sildenafil	C0231528	myalgia	1	[Q08499]	DRUG	0.133343956
L04AX02	thalidomide	C0033975	psychosis	1	[Q99259]	METABOLITE	0.298520953
L04AA06	mycophenolic acid	C0042373	Vascular Disorders	1	[P37231]	DRUG_AND_METABOLITE	0.044620172
G03BA03	testosterone	C0020565	breast enlargement	2	[P11511, P03372]	METABOLITE	0.082415968
M01AH03	valdecoxib	C0024299	lymphoma	1	[P35354]	DRUG_AND_METABOLITE	0.426935507
N03AG01	valproic acid	C0023530	leukopenia	1	[O60656]	DRUG	0.11155512
N03AG01	valproic acid	C0011991	diarrhea	1	[O60656]	DRUG	0.072104339
N05AH03	olanzapine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.061456377
J04AC01	isoniazid	C0031117	peripheral neuropathy	1	[P14780]	METABOLITE	0.037934867
S01ED02	betaxolol	C0015230	rash	2	[P07550, P08908]	METABOLITE	0.038822848
N07BB04	naltrexone	C0086769	panic attacks	2	[P31645, P23975]	DRUG	0.002408295
R06AX17	ketotifen	C0015230	rash	2	[P28223, P08908]	METABOLITE	0.077843187
H02AB07	prednisone	C0009951	convulsions	1	[P08183]	DRUG_AND_METABOLITE	0.19472871
N07BC02	methadone	C0011991	diarrhea	1	[P46098]	METABOLITE	0.089636267
N04BC04	ropinirole	C0013604	edema	1	[P08588]	DRUG	0.037128649
C01CA24	epinephrine	C0018799	heart disease	3	[P08588, P11712, P07550]	DRUG_AND_METABOLITE	0.050504261
C09AA10	trandolapril	C0035078	renal failure	1	[P12821]	DRUG_AND_METABOLITE	0.032885129
C01BA01	quinidine	C0027947	neutropenia	2	[Q92887, P08183]	DRUG	0.017207121
N05AH04	quetiapine	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.168431086
B01AC07	dipyridamole	C0038454	cerebrovascular accident	1	[Q08499]	DRUG	0.161491924
N07XX02	riluzole	C0030305	pancreatitis	2	[Q99895, P04798]	DRUG	0.020730341
A02BC02	pantoprazole	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.110330226
N02CC01	sumatriptan	C0008031	chest pain	1	[P02768]	METABOLITE	0.028717627
A16AA04	cysteamine	C0015230	rash	5	[P07550, P28223, P08908, P31645, P09211]	DRUG	0.023991569
N06AA21	maprotiline	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.039009407
M04AA01	allopurinol	C0041948	uremia	1	[P00813]	METABOLITE	0.364398253
R01AD01	beclomethasone	C0041912	upper respiratory tract infection	4	[P35228, P35354, P23219, P09917]	DRUG_AND_METABOLITE	0.133832308
C07AB07	bisoprolol	C0027051	myocardial infarction	3	[P13945, P07550, P08588]	DRUG_AND_METABOLITE	0.00225078
C09CA01	losartan	C0442874	neuropathy	2	[P12821, P08183]	DRUG	0.021299045
M01AH03	valdecoxib	C0018802	congestive heart failure	1	[Q9Y2I1]	DRUG_AND_METABOLITE	0.194818503
B01AC05	ticlopidine	C0151798	hepatic necrosis	1	[P08684]	DRUG_AND_METABOLITE	0.161461453
N05AH03	olanzapine	C0013595	eczema	5	[P07550, P21731, P28223, P08908, P31645]	DRUG	0.009521978
M01AH03	valdecoxib	C0024312	lymphopenia	1	[O60656]	DRUG_AND_METABOLITE	0.07311681
C01BB02	mexiletine	C0013604	edema	1	[P08588]	METABOLITE	0.06589552
C01BA02	procainamide	C0018524	hallucinations	3	[P35498, Q99250, Q9NY46]	DRUG	0.000930987
M01AX01	nabumetone	C0030305	pancreatitis	2	[P07858, P35354]	DRUG_AND_METABOLITE	0.006723816
P01AX06	atovaquone	C0015230	rash	8	[P07550, P01024, P26358, P28223, P08908, P31645, P50135, P09211]	METABOLITE	0.008079398
L01XE01	imatinib	C0006826	cancer	102	[P04626, Q04912, P42336, P08183, P29317, P00533, Q9UIK4, P31749, Q9UK32, P17252, Q15375, Q02763, P37173, P36897, P10721, P53350, P51955, P45983, Q16539, P21802, P22607, P45985, Q9P289, P07333, P52799, P09619, P16234, Q08345, Q16790, P43405, O75582, Q13153, P08581, P15056, Q92918, Q15831, P07949, O14965, P43403, P12931, P53355, Q9UNQ0, P50613, P08069, Q96GD4, Q13873, P20815, Q05397, O43293, Q13882, P08684, Q16832, P04629, P35916, P17948, O14757, P23219, P05177, P45984, P35968, P54762, P54760, P49841, Q13547, O60674, P07332, P28482, P11362, Q9UM73, P52333, Q02156, Q05655, P27361, P06213, P24941, O43570, P06748, P00519, P29597, P29323, P19525, P22455, P06239, P68400, P53667, Q13164, P24723, P36894, P07948, Q00526, P06241, O95835, P21709, Q02750, P31751, P36507, Q14289, Q9Y243, Q9UBN7, P49840, Q9NRM7, P23458]	DRUG	0.000156554
M01AB05	diclofenac	C0019158	hepatitis	4	[P05181, P23219, P35354, P02768]	DRUG	0.00316216
J05AE01	saquinavir	C0018944	hematoma	1	[P11712]	DRUG	0.064439777
G02CB03	cabergoline	C0018824	valvular heart disease	2	[P08588, P07550]	DRUG	0.062960049
J04AC01	isoniazid	C0024141	lupus	3	[P14780, P11245, P18440]	DRUG	0.022175251
N03AE01	clonazepam	C0260653	Behavior Problems	1	[P21397]	DRUG_AND_METABOLITE	0.022963468
A02BC03	lansoprazole	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.062641595
G02CB03	cabergoline	C0018801	heart failure	1	[P07550]	DRUG	0.105662609
C07AB04	acebutolol	C0011570	mental depression	2	[P28222, P08908]	DRUG	0.002548336
N05AE04	ziprasidone	C0014394	enuresis	2	[P28223, P21917]	DRUG	0.012286028
N02AX02	tramadol	C0032584	polyps	1	[P23975]	DRUG_AND_METABOLITE	0.461170573
C09AA08	cilazapril	C0027051	myocardial infarction	1	[P12821]	DRUG	0.101781344
G03HA01	cyproterone	C0027051	myocardial infarction	1	[P10275]	DRUG	0.085527439
G03XC01	raloxifene	C0149871	deep vein thrombosis	2	[P03372, Q92731]	DRUG	0.010647008
G03CA03	estradiol	C0009443	common cold	1	[P03372]	DRUG_AND_METABOLITE	0.499995859
S01EA02	dipivefrin	C0039231	tachycardia	2	[P07550, P08588]	METABOLITE	0.001248928
N05AX08	risperidone	C0018524	hallucinations	2	[P08183, P36544]	DRUG_AND_METABOLITE	0.063596471
N04BX01	tolcapone	C0021311	infection	1	[P27487]	METABOLITE	0.325990764
C09AA05	ramipril	C0015672	fatigue	1	[P12821]	DRUG	0.010207101
N03AG01	valproic acid	C0017152	gastritis	1	[P23219]	DRUG	0.126771139
C07AG01	labetalol	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.002812013
G03XC01	raloxifene	C0149931	migraine	2	[P03372, P08684]	DRUG	0.007508225
N07BB04	naltrexone	C0004093	asthenia	1	[P31645]	DRUG	0.025953097
N06AB06	sertraline	C1527304	allergic reaction	2	[Q01959, P35367]	DRUG_AND_METABOLITE	0.017421156
J01AA08	minocycline	C0022660	acute renal failure	1	[P15692]	DRUG	0.048595777
C03DA04	eplerenone	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.156888602
L01BA01	methotrexate	C0010823	CMV infection	1	[P04818]	DRUG_AND_METABOLITE	0.090151367
A05AA02	ursodeoxycholic acid	C0011849	diabetes mellitus	1	[P11473]	METABOLITE	0.220108265
R06AE07	cetirizine	C1527304	allergic reaction	2	[P35367, Q9H3N8]	DRUG	0.000604572
C01EB03	indomethacin	C0242422	Parkinson	5	[P08183, P10145, P21554, P35354, Q9UQD0]	DRUG	0.010312486
C03DA04	eplerenone	C0011860	type 2 diabetes	1	[P08684]	DRUG	0.134968191
A02BC04	rabeprazole	C0032285	pneumonia	1	[P35354]	DRUG	0.178569817
S01EE03	bimatoprost	C0017601	glaucoma	1	[P43088]	DRUG_AND_METABOLITE	0.042475697
N05CD02	nitrazepam	C0018524	hallucinations	3	[P08183, P35498, P33527]	DRUG	0.019115398
D01AC03	econazole	C0015230	rash	1	[P09601]	DRUG	0.100741343
N02AX02	tramadol	C0678222	breast cancer	2	[P08684, P20813]	DRUG	0.446250816
C07AA03	pindolol	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	3.15166E-05
G02CB03	cabergoline	C0018799	heart disease	3	[P08588, P07550, P41595]	DRUG	0.029674925
N01BB09	ropivacaine	C0428977	bradycardia	1	[Q14524]	METABOLITE	0.020983013
C01EB03	indomethacin	C0011991	diarrhea	3	[P10145, Q92887, O60656]	DRUG	0.000773789
N04BD01	selegiline	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG_AND_METABOLITE	2.56983E-06
N04BD01	selegiline	C0684249	lung cancer	8	[P11509, P05181, P08183, P11712, P33261, P05177, P08684, P10632]	DRUG	0.033221489
M01AH01	celecoxib	C0021311	infection	4	[P35354, P23219, Q16539, P09917]	DRUG	0.340884981
N06AA09	amitriptyline	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.119299289
G04CA02	tamsulosin	C0021311	infection	3	[Q9BPW9, P35354, P23219]	METABOLITE	0.15703101
N07BA01	nicotine	C0020517	hypersensitivity	1	[O75762]	DRUG	0.145989685
N06AB04	citalopram	C0010054	coronary artery disease	1	[P08684]	DRUG	0.268026518
C07AG02	carvedilol	C0022660	acute renal failure	1	[P15692]	DRUG	0.048595777
N07BA01	nicotine	C0020538	hypertension	2	[O15244, P11712]	DRUG	0.264657152
N07XX02	riluzole	C0042133	uterine fibroids	1	[P04798]	DRUG	0.111668845
N05AX08	risperidone	C0221765	chronic schizophrenic	23	[P35462, P28223, P36544, P32238, P11229, P08912, P21917, P14416, P28335, P21728, P28222, P08908, P20815, P31645, Q01959, P25103, P50406, P35367, P35372, P21554, P17787, P08173, P08183]	DRUG	0
C01BC04	flecainide	C0428977	bradycardia	1	[Q14524]	DRUG	0.010207101
N06DA03	rivastigmine	C0009806	constipation	1	[P31645]	DRUG	0.015405718
M01AB05	diclofenac	C0243026	sepsis	1	[P10145]	DRUG_AND_METABOLITE	0.27636645
C08CA05	nifedipine	C0027051	myocardial infarction	4	[P04798, P11712, P05177, P18089]	DRUG	0.100666416
B01AA03	warfarin	C0027651	tumor	6	[P04798, P08684, P05177, P10632, Q9BQB6, P33261]	DRUG	0.14737653
L02BA01	tamoxifen	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.100741343
N06AA01	desipramine	C0015230	rash	5	[P07550, P28223, P08908, P31645, P17405]	DRUG	0.018613941
M01AB08	etodolac	C0011991	diarrhea	2	[O60656, P16662]	DRUG	0.001282425
N06AB05	paroxetine	C0018524	hallucinations	1	[P08183]	DRUG	0.135763824
C07AB03	atenolol	C0001824	agranulocytosis	1	[P08183]	DRUG	0.039009407
L04AA13	leflunomide	C0042109	urticaria	1	[P09917]	DRUG	0.037354197
S01AA14	penicillin G	C0027947	neutropenia	1	[P08183]	METABOLITE	0.101130087
C01EB03	indomethacin	C0002878	hemolytic anemia	1	[P22309]	DRUG	0.113170518
C01EB03	indomethacin	C0002871	anemia	2	[P10145, P02768]	DRUG	0.044396476
G04CB02	dutasteride	C0001430	adenomas	1	[P26439]	DRUG_AND_METABOLITE	0.111784073
N05AH03	olanzapine	C0002871	anemia	1	[P02768]	DRUG	0.187538464
D01AE22	naftifine	C0015230	rash	2	[P37231, P08908]	DRUG	0.030728948
M01AC01	piroxicam	C0004096	asthma	3	[P09917, P35354, P23219]	DRUG_AND_METABOLITE	0.005396749
M01AC01	piroxicam	C0004093	asthenia	1	[P35354]	DRUG_AND_METABOLITE	0.019239124
N04BD01	selegiline	C1527304	allergic reaction	2	[P41595, Q01959]	METABOLITE	0.021747559
N05AH03	olanzapine	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG	0.010731647
G02CB01	bromocriptine	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG	0.027818585
B01AC04	clopidogrel	C0019080	hemorrhage	1	[P11712]	DRUG	0.037128649
N05AH03	olanzapine	C0019158	hepatitis	1	[P02768]	DRUG	0.206878508
J05AE01	saquinavir	C1261473	sarcoma	1	[P08183]	DRUG	0.16513393
G03BA03	testosterone	C0152032	urinary hesitancy	2	[P02768, P00918]	METABOLITE	0.136736071
N02CA01	dihydroergotamine	C0011991	diarrhea	1	[P46098]	DRUG	0.085261294
N03AD01	ethosuximide	C1527304	allergic reaction	1	[P35367]	DRUG	0.040601904
M01AB05	diclofenac	C0013595	eczema	2	[P28223, P08908]	DRUG	0.157523633
N05AX08	risperidone	C0014130	Endocrine Disorders	2	[Q12809, P32239]	DRUG_AND_METABOLITE	0.261851938
N02CA01	dihydroergotamine	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.004601015
R03DC03	montelukast	C0043144	wheezing	5	[P09917, Q9Y271, P23219, Q9NS75, O94956]	DRUG_AND_METABOLITE	5.96446E-05
M01AE09	flurbiprofen	C0024115	lung disorder	5	[P25024, P10145, P22309, P08246, P35354]	DRUG_AND_METABOLITE	0.003110213
N04BD01	selegiline	C0027813	neuritis	1	[P08183]	DRUG	0.103034195
N05CD01	flurazepam	C0023530	leukopenia	1	[P08183]	DRUG	0.067909151
C01BA01	quinidine	C0039231	tachycardia	1	[Q14524]	DRUG	0.0483478
A02BC04	rabeprazole	C0010709	cyst	6	[P05177, P08183, P35354, Q9UNQ0, Q16678, P04798]	DRUG_AND_METABOLITE	0.414190699
N06AX16	venlafaxine	C0026764	multiple myeloma	2	[P08183, P33261]	DRUG	0.29926214
A02BB01	misoprostol	C0011603	dermatitis	4	[P21731, Q9Y5Y4, Q13258, Q07869]	METABOLITE	0.000903387
G03AC06	medroxyprogesterone	C0027726	nephrotic syndrome	1	[P04150]	DRUG_AND_METABOLITE	0.11842652
N06DA03	rivastigmine	C0009951	convulsions	1	[P31645]	DRUG	0.082841128
N02CA01	dihydroergotamine	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.497068996
N07BC02	methadone	C1510472	drug dependence	1	[P41595]	METABOLITE	0.040557986
C09AA02	enalapril	C0033687	proteinuria	2	[P12821, Q9BYF1]	DRUG_AND_METABOLITE	0.00185428
A02BC02	pantoprazole	C0030305	pancreatitis	2	[Q99895, P04798]	METABOLITE	0.039009407
A07EC01	sulfasalazine	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.128451012
R03AC13	formoterol	C0684249	lung cancer	3	[P11509, P11712, P33261]	DRUG	0.023690342
J01EC02	sulfadiazine	C0030305	pancreatitis	2	[Q99895, P05181]	DRUG	0.013083066
A02BC04	rabeprazole	C0036572	seizures	1	[P50993]	METABOLITE	0.092835044
L02BB01	flutamide	C1458155	breast neoplasm	10	[P04798, Q16678, P08684, P06401, P35869, P05177, P10275, P20813, Q12809, P20815]	DRUG	0.357244507
N06AA01	desipramine	C0038454	cerebrovascular accident	3	[P05362, P28223, P07550]	DRUG	0.089763822
N05CD02	nitrazepam	C0001824	agranulocytosis	1	[P08183]	DRUG	0.118055255
N07XX02	riluzole	C0010709	cyst	4	[P05177, O15554, Q9UNQ0, P04798]	DRUG	0.139099062
A02BC02	pantoprazole	C0018524	hallucinations	2	[P08183, P50993]	DRUG_AND_METABOLITE	0.021793623
L04AX02	thalidomide	C0011053	deafness	1	[Q14831]	METABOLITE	0.236166005
N03AG01	valproic acid	C0023895	liver disease	1	[P08684]	DRUG	0.236442909
N03AG01	valproic acid	C0023890	cirrhosis	2	[P08684, P13726]	DRUG	0.111308303
C08CA05	nifedipine	C1527304	allergic reaction	1	[O75762]	DRUG	0.124559086
J05AE01	saquinavir	C0018799	heart disease	3	[P11712, Q92887, P33527]	DRUG	0.027450638
N02CC01	sumatriptan	C0020615	hypoglycemia	1	[P07550]	DRUG	0.113256525
N05AA01	chlorpromazine	C0026266	mitral insufficiency	11	[P05362, Q12809, P48544, P23219, P31645, P35354, P08588, P11712, P07550, P20813, P23975]	DRUG_AND_METABOLITE	0.001103208
N05AD01	haloperidol	C0037763	spasm	1	[P21918]	DRUG	0.090619814
M01AH01	celecoxib	C0029927	ovarian cyst	1	[P35354]	DRUG_AND_METABOLITE	0.11576137
D05BB02	acitretin	C0021311	infection	3	[P35354, P23219, P05067]	METABOLITE	0.166541931
G04BE08	tadalafil	C0027051	myocardial infarction	1	[Q08499]	DRUG	0.335953544
C07AA07	sotalol	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.28077306
A07DA03	loperamide	C0020517	hypersensitivity	2	[P35367, P25021]	METABOLITE	0.016226908
M01AE03	ketoprofen	C0025290	aseptic meningitis	1	[P10145]	DRUG	0.031878908
N03AX16	pregabalin	C0151514	skin atrophy	1	[O00555]	DRUG	0.100398034
N06AA02	imipramine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.001536633
N07XX02	riluzole	C0042510	ventricular fibrillation	1	[Q14524]	DRUG	0.010569187
N07BC02	methadone	C0004093	asthenia	2	[P31645, P28223]	METABOLITE	0.00910175
M01AE12	oxaprozin	C0013395	Dyspepsia	1	[P23219]	DRUG	0.012792437
C07AG02	carvedilol	C0007820	cerebrovascular disorder	3	[P16860, P19320, P07550]	DRUG_AND_METABOLITE	0.019028106
G03BA03	testosterone	C0032584	polyps	17	[P05177, P08183, P06401, P03372, Q92731, P08842, Q9UNQ0, P31213, P11511, P20815, Q16678, P50225, P22309, P18405, P04798, P10275, P11474]	METABOLITE	0.157091582
L01BA01	methotrexate	C0035078	renal failure	2	[P08183, P42898]	DRUG	0.02752174
N06AB08	fluvoxamine	C0033975	psychosis	3	[P28223, P31645, P08908]	DRUG_AND_METABOLITE	0.002217487
N06AB06	sertraline	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG_AND_METABOLITE	1.30886E-06
N05AH03	olanzapine	C0019080	hemorrhage	1	[P21731]	DRUG	0.141091994
N02CA01	dihydroergotamine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.008079398
R03AC02	salbutamol	C0039239	sinus tachycardia	2	[P07550, P08588]	DRUG	6.31065E-05
N07XX02	riluzole	C0042514	ventricular tachycardia	1	[Q14524]	DRUG	0.023338897
R03AC02	salbutamol	C0039231	tachycardia	2	[P07550, P08588]	DRUG	6.31065E-05
N06AX21	duloxetine	C0026821	muscle cramps	1	[Q8NER1]	DRUG	0.056135953
G03AC06	medroxyprogesterone	C0027813	neuritis	1	[P08183]	DRUG_AND_METABOLITE	0.040601904
C09AA05	ramipril	C0442874	neuropathy	1	[P12821]	DRUG	0.028343005
N06AX06	nefazodone	C0023530	leukopenia	1	[P08183]	DRUG	0.106607126
G04CB02	dutasteride	C0600139	prostate cancer	6	[P20815, P18405, P08684, P26439, P14060, P31213]	DRUG_AND_METABOLITE	0.002077385
N05AE04	ziprasidone	C0031212	personality disorder	1	[P31645]	DRUG_AND_METABOLITE	0.041143563
N03AF01	carbamazepine	C0033975	psychosis	2	[P28223, P08908]	DRUG	0.026625335
C09AA07	benazepril	C0020517	hypersensitivity	1	[P42898]	DRUG	0.030094767
L04AX02	thalidomide	C0007859	neck pain	1	[Q08499]	DRUG	0.058400414
C07AA05	propranolol	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.004167423
J01AA08	minocycline	C0034152	anaphylactoid purpura	2	[P01584, P14780]	DRUG	0.004013279
J01MA06	norfloxacin	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.108434198
M01AB05	diclofenac	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.054935903
G03CA03	estradiol	C0149741	nipple discharge	1	[P03372]	DRUG_AND_METABOLITE	0.085892844
J05AE01	saquinavir	C0018824	valvular heart disease	1	[P11712]	DRUG	0.199461871
M01AH03	valdecoxib	C0017168	gastroesophageal reflux	1	[P33261]	DRUG_AND_METABOLITE	0.087781953
G04CA03	terazosin	C0011991	diarrhea	1	[P46098]	DRUG	0.070199651
G03AC06	medroxyprogesterone	C0027651	tumor	9	[P08684, P03372, P08183, P06401, P08235, P10275, P04150, P10632, P26439]	DRUG_AND_METABOLITE	0.002834549
M01AH03	valdecoxib	C0017152	gastritis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.034691983
N06AB05	paroxetine	C0018799	heart disease	5	[P31645, P08588, P11712, P20813, P41595]	DRUG	0.007455605
N06AX16	venlafaxine	C0026848	myopathy	2	[P17252, P29475]	DRUG	0.137533792
C07AB03	atenolol	C0013604	edema	1	[P08588]	DRUG	0.021299045
A16AA04	cysteamine	C0042109	urticaria	1	[P07550]	METABOLITE	0.12340561
M01AH01	celecoxib	C0017601	glaucoma	1	[O43570]	DRUG	0.134991257
N05CD02	nitrazepam	C0001957	delirium tremens	1	[P21554]	DRUG	0.047800851
S01ED02	betaxolol	C0027051	myocardial infarction	5	[P13945, P07550, P33261, P05177, P08588]	DRUG_AND_METABOLITE	0.00158723
M04AA01	allopurinol	C0231528	myalgia	1	[Q08499]	METABOLITE	0.250410781
M01AB05	diclofenac	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.136554131
L01BA01	methotrexate	C0011991	diarrhea	1	[Q92887]	DRUG	0.057691049
M01AE01	ibuprofen	C0020538	hypertension	9	[P35348, P21728, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089]	DRUG	0.006002348
M01AE02	naproxen	C0678222	breast cancer	19	[P35354, P42330, P33527, P22309, Q99720, P63000, P18031, P46721, P05177, P07858, P60953, P49810, P09917, Q9Y618, Q01959, Q9H3N8, P10632, Q9Y5N1, P23219]	DRUG	0.114588485
L01XX11	estramustine	C0002871	anemia	1	[P02768]	METABOLITE	0.142309143
N05CF03	zaleplon	C0012833	dizziness	1	[P29274]	DRUG	0.010207101
N04BD01	selegiline	C0027651	tumor	16	[P08684, P08183, Q99720, P05181, P05177, P20813, Q01959, P10632, P11509, Q05940, P23975, P07477, O75751, P33261, P35348, O60341]	METABOLITE	0.292950503
N01BB09	ropivacaine	C0042510	ventricular fibrillation	1	[Q14524]	METABOLITE	0.016580154
L04AA13	leflunomide	C0030305	pancreatitis	1	[Q99895]	DRUG	0.094952502
N01BB09	ropivacaine	C0042514	ventricular tachycardia	1	[Q14524]	METABOLITE	0.035695087
N05AX08	risperidone	C0018944	hematoma	1	[P21731]	DRUG_AND_METABOLITE	0.133599847
C09AA08	cilazapril	C0006266	bronchospasm	1	[P12821]	DRUG	0.092356341
M01AB02	sulindac	C0030305	pancreatitis	2	[P04798, P35354]	DRUG_AND_METABOLITE	0.028957228
N05CF03	zaleplon	C0004096	asthma	2	[P03956, P29274]	DRUG	0.04394482
L02AB01	megestrol	C1261473	sarcoma	1	[P08183]	DRUG	0.085527439
A05AA02	ursodeoxycholic acid	C0011991	diarrhea	1	[Q92887]	DRUG_AND_METABOLITE	0.035047926
N06AB08	fluvoxamine	C0033860	psoriasis	1	[P04798]	DRUG_AND_METABOLITE	0.178422089
G04BD04	oxybutynin	C0004096	asthma	2	[P11229, P20309]	DRUG	0.038869302
N05AH04	quetiapine	C0021311	infection	1	[P07550]	DRUG	0.499995859
L04AX02	thalidomide	C1527304	allergic reaction	1	[P01375]	DRUG	0.217576661
J01MA14	moxifloxacin	C0027651	tumor	2	[P11388, Q12809]	DRUG	0.095256162
L04AX02	thalidomide	C0019348	herpes simplex	1	[P19838]	DRUG	0.287888091
N02AA03	hydromorphone	C0041948	uremia	1	[P35348]	METABOLITE	0.214159974
J02AC01	fluconazole	C0027947	neutropenia	1	[P08183]	DRUG	0.037092814
C07AB02	metoprolol	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.024401265
C08CA05	nifedipine	C0039070	syncope	1	[P29274]	DRUG	0.053677028
J05AF03	zalcitabine	C0009951	convulsions	2	[P33527, P54098]	METABOLITE	0.071241753
C08DA01	verapamil	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.00739731
R03AC13	formoterol	C0013604	edema	1	[P08588]	DRUG	0.015405718
G03DA04	progesterone	C0476089	endometrial cancer	16	[Q04828, P06401, P03372, P31213, P08183, P11511, P05108, Q16678, P04798, P14061, P05093, P10275, P08684, P04278, O75469, Q92731]	DRUG_AND_METABOLITE	9.85161E-08
N06AX16	venlafaxine	C0003811	arrhythmia	1	[Q14524]	METABOLITE	0.09505443
N06AX16	venlafaxine	C0686347	tardive dyskinesia	2	[P35498, Q12791]	DRUG	0.012792437
N04BB01	amantadine	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.082202439
N06AX05	trazodone	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.005292839
C09AA03	lisinopril	C0031117	peripheral neuropathy	2	[P12821, P08183]	DRUG	0.000147486
G03DA04	progesterone	C0678222	breast cancer	33	[Q9UNQ0, P04798, Q16678, P11511, P08684, P03372, Q15788, P08183, P06401, P19793, Q92731, P04278, O75469, P15531, P33527, Q99720, P52895, Q04828, P08235, O00591, P14061, Q96RI1, P05093, P46721, P05108, P05181, P05177, P10275, P20813, P04150, P20815, P10632, P18405]	DRUG_AND_METABOLITE	0.028848805
C01EB03	indomethacin	C0004096	asthma	9	[P09917, Q13258, P10145, P35354, P23219, Q9Y5Y4, P43115, P37231, P33527]	DRUG	0.000434556
N06AB04	citalopram	C0022116	ischemia	1	[P05181]	DRUG	0.1248945
N06AB05	paroxetine	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.03976834
L04AA13	leflunomide	C0014130	Endocrine Disorders	1	[P03956]	DRUG	0.161084657
N06AA10	nortriptyline	C0019158	hepatitis	4	[P05181, P23219, P11509, P02768]	DRUG	0.004962197
L01BA01	methotrexate	C0041912	upper respiratory tract infection	2	[P42898, P47989]	DRUG	0.342977802
N02AX02	tramadol	C0020538	hypertension	3	[P35348, P31645, P23975]	DRUG_AND_METABOLITE	0.018473648
A07EC01	sulfasalazine	C0151798	hepatic necrosis	4	[P09211, Q92887, P37231, P08684]	METABOLITE	0.001834856
V03AH01	diazoxide	C0001339	acute pancreatitis	1	[P00918]	DRUG	0.094952502
N06AX16	venlafaxine	C0003873	rheumatoid arthritis	4	[P34972, P25103, P21554, P07550]	DRUG	0.337113972
N07AA02	pyridostigmine	C0042024	urinary incontinence	1	[P08172]	DRUG	0.022436068
N06AB04	citalopram	C0027651	tumor	10	[P08684, P08183, P05181, P05177, P20813, Q01959, Q12809, P23975, P33261, P35348]	DRUG	0.313729683
C01EB03	indomethacin	C0041582	ulcer	2	[P10145, P37231]	DRUG	0.008998461
L01XE03	erlotinib	C0015230	rash	1	[P04629]	DRUG_AND_METABOLITE	0.499995859
A10BG02	rosiglitazone	C0019158	hepatitis	2	[P23219, P11509]	DRUG	0.014022221
N06AA06	trimipramine	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.051022002
M01AE02	naproxen	C0027651	tumor	24	[P35354, P42330, P33527, P22309, Q99720, P63000, P18031, P46721, P05177, P07858, P60953, P49810, P09917, Q9Y618, Q01959, Q9H3N8, P10632, Q9Y5N1, P23219, P23975, P41222, P34972, P21554, P35348]	DRUG	0.286457673
B01AA03	warfarin	C0008031	chest pain	1	[P02768]	DRUG	0.011557989
C10AA06	cerivastatin	C0013295	duodenal ulcer	1	[P33261]	DRUG_AND_METABOLITE	0.040283843
C09AA03	lisinopril	C0042109	urticaria	1	[P12821]	DRUG	0.018096702
N03AX11	topiramate	C0013384	dyskinesia	1	[P35498]	DRUG	0.078146652
C09AA09	fosinopril	C0004096	asthma	1	[P12821]	DRUG	0.077274451
N04BC04	ropinirole	C0001418	adenocarcinoma	3	[P07550, P08684, P05177]	DRUG	0.439918533
C08CA05	nifedipine	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.025031074
G03DA04	progesterone	C0231528	myalgia	1	[Q9Y6L6]	METABOLITE	0.266983099
R03AC13	formoterol	C0003873	rheumatoid arthritis	2	[P13945, P07550]	DRUG	0.04687583
G03BA03	testosterone	C0497481	Penile Pain	1	[P11511]	DRUG_AND_METABOLITE	0.041899613
C10AA03	pravastatin	C0022346	jaundice	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.022511552
R03AC13	formoterol	C0003850	arteriosclerosis	3	[P13945, P11712, P33261]	DRUG	0.006501258
A02BC02	pantoprazole	C0027651	tumor	8	[Q9UNQ0, P04798, Q16678, P08684, P08183, P05177, P10632, P33261]	DRUG_AND_METABOLITE	0.422042983
M01AE12	oxaprozin	C0020456	hyperglycemia	1	[P35354]	DRUG	0.039691524
L02BB01	flutamide	C0020538	hypertension	4	[P20815, P35348, O15244, P11712]	METABOLITE	0.054069386
N06AX16	venlafaxine	C0027051	myocardial infarction	8	[P21554, P07550, P11712, P33261, P31645, P08588, P18089, Q12791]	DRUG	0.026016377
C01EB03	indomethacin	C0728731	prematurity	1	[P37231]	DRUG	0.104314558
J05AF01	zidovudine	C0085662	macrocytosis	1	[P02768]	DRUG	0.089912296
B01AA03	warfarin	C0019158	hepatitis	1	[P02768]	DRUG	0.067564802
N06BA09	atomoxetine	C0011603	dermatitis	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.059770251
G04BE03	sildenafil	C0149931	migraine	1	[P08684]	DRUG	0.105026994
H02AB06	prednisolone	C0040046	thrombophlebitis	2	[P03372, Q92731]	DRUG_AND_METABOLITE	0.018613941
N02AE01	buprenorphine	C0021311	infection	1	[P01189]	METABOLITE	0.421491371
J05AF04	stavudine	C0085662	macrocytosis	1	[P02768]	METABOLITE	0.105876857
N02AX02	tramadol	C0012813	diverticulitis	1	[P31645]	DRUG_AND_METABOLITE	0.036486436
N06BA09	atomoxetine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.007907224
R06AB04	chlorpheniramine	C0043144	wheezing	2	[P11229, P20309]	DRUG	0.16144089
M01AB15	ketorolac	C0030920	peptic ulcer	3	[P35354, P10145, P23219]	DRUG	0.000405161
N02CC02	naratriptan	C0009951	convulsions	1	[P08908]	DRUG	0.06589552
M01AH03	valdecoxib	C0699791	gastric carcinoma	4	[P35354, P33527, P23219, P33261]	DRUG_AND_METABOLITE	0.285000297
N05CF02	zolpidem	C0027051	myocardial infarction	4	[P11712, P33261, P23219, P05177]	DRUG	0.022484145
D05BB02	acitretin	C0232726	tenesmus	1	[P11511]	METABOLITE	0.105895855
C01BB02	mexiletine	C0018524	hallucinations	3	[P36544, P35498, Q99250]	DRUG	0.020705536
M01AB15	ketorolac	C0001339	acute pancreatitis	1	[P35354]	DRUG	0.116501515
R06AB04	chlorpheniramine	C0009951	convulsions	4	[P35498, Q99250, Q9NY46, P31645]	DRUG	0.004408314
L02BG03	anastrozole	C0030794	pelvic pain	1	[P11511]	DRUG	0.016169699
S01AA14	penicillin G	C0015230	rash	1	[P12319]	DRUG	0.32312495
G02CB01	bromocriptine	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG	4.2511E-05
N05AB02	fluphenazine	C0037763	spasm	2	[P21918, P28472]	DRUG	0.005418641
N04BC05	pramipexole	C0007784	cerebral hemorrhage	2	[P28223, P07550]	DRUG	0.102102193
C07AA15	carteolol	C0020615	hypoglycemia	1	[P07550]	DRUG	0.038275109
A02BC04	rabeprazole	C0699893	skin carcinoma	4	[P35354, Q9UNQ0, P23219, P04798]	DRUG_AND_METABOLITE	0.280349021
G04BE08	tadalafil	C0030193	pain	1	[Q08499]	DRUG	0.03201379
G04BE08	tadalafil	C0030196	Pain in limb	1	[Q08499]	DRUG	0.019028106
N02AA03	hydromorphone	C0020538	hypertension	7	[P20815, P35348, P21728, P31645, P11712, P23975, P21964]	DRUG_AND_METABOLITE	0.000948536
C10AA06	cerivastatin	C0151798	hepatic necrosis	2	[Q92887, P08684]	DRUG_AND_METABOLITE	0.019381901
M01AH01	celecoxib	C1458155	breast neoplasm	11	[P08684, P35354, Q16539, P33527, Q16790, Q99720, P18054, P09917, Q01959, O43570, P23975]	DRUG	0.473363452
N02AA05	oxycodone	C0004093	asthenia	1	[P31645]	DRUG	0.021841092
H03BB02	methimazole	C0019158	hepatitis	2	[P05181, P11509]	DRUG	0.01008194
M01AH01	celecoxib	C0009319	colitis	5	[P00918, P31645, P35354, P46098, P41595]	DRUG	0.011740874
G03AC06	medroxyprogesterone	C0728731	prematurity	1	[P04150]	DRUG_AND_METABOLITE	0.036033671
G04CA01	alfuzosin	C0023895	liver disease	1	[P08684]	DRUG	0.047322811
N04BD01	selegiline	C0004998	skin benign neoplasm	7	[P05177, P11509, P08183, P05181, Q05940, P23975, P07477]	METABOLITE	0.287629776
C01BB01	lidocaine	C0020538	hypertension	4	[P20815, P22460, P11712, P18054]	METABOLITE	0.034547486
M01AE12	oxaprozin	C0020538	hypertension	1	[P11712]	DRUG	0.119954952
C01BB01	lidocaine	C0020517	hypersensitivity	1	[P00533]	DRUG	0.116131818
C08CA05	nifedipine	C0011603	dermatitis	1	[P28223]	DRUG	0.385039541
A04AA02	granisetron	C0011603	dermatitis	2	[P28223, P08908]	DRUG_AND_METABOLITE	0.086024123
C10AA02	lovastatin	C0013404	dyspnea	1	[P80365]	METABOLITE	0.239861996
N03AX16	pregabalin	C0033578	prostate neoplasia	1	[Q01650]	DRUG	0.460940143
M01AB15	ketorolac	C0017152	gastritis	3	[P10145, P23219, P35354]	DRUG	0.00047115
C01BD01	amiodarone	C0549473	thyroid cancer	2	[P10827, P10828]	DRUG_AND_METABOLITE	0.097523567
N05BA01	diazepam	C0021311	infection	2	[P08575, P23219]	DRUG	0.449998568
L02BA01	tamoxifen	C1458155	breast neoplasm	20	[Q9UNQ0, P04798, Q16678, P11511, P08684, P03372, P35354, Q99527, P08183, P17252, Q92731, Q99720, P05181, P05177, P10275, P20813, Q13393, P11509, P05771, P20815]	DRUG	0.002913903
B01AA03	warfarin	C0019080	hemorrhage	2	[P11712, Q9BQB6]	DRUG	0.003433538
N03AB02	phenytoin	C0019158	hepatitis	2	[P05181, P02768]	DRUG	0.042804682
L01XE03	erlotinib	C0003123	anorexia	1	[Q16620]	DRUG_AND_METABOLITE	0.382742428
N06AA02	imipramine	C0033975	psychosis	8	[P35462, P28223, P21917, Q13639, P21397, P28222, P31645, P08908]	DRUG_AND_METABOLITE	4.55542E-05
G03DA04	progesterone	C0149931	migraine	4	[P03372, P28223, P50993, P08684]	DRUG_AND_METABOLITE	0.003826662
M01AE01	ibuprofen	C0025290	aseptic meningitis	1	[P10145]	DRUG	0.08493061
L01XE02	gefitinib	C0030305	pancreatitis	1	[P15056]	DRUG_AND_METABOLITE	0.486866165
N05AG02	pimozide	C0023530	leukopenia	2	[O60656, P08183]	DRUG	0.044555324
C08DB01	diltiazem	C0015672	fatigue	1	[P28223]	DRUG	0.043339606
G02CB01	bromocriptine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	3.59294E-07
N05BE01	buspirone	C0037763	spasm	2	[P14867, P21918]	DRUG_AND_METABOLITE	0.011866315
M01AH03	valdecoxib	C0020456	hyperglycemia	1	[P35354]	DRUG_AND_METABOLITE	0.167395635
N03AX09	lamotrigine	C0035078	renal failure	1	[P08183]	DRUG	0.074465973
C09AA01	captopril	C0030305	pancreatitis	1	[P09211]	METABOLITE	0.128824251
L02BA01	tamoxifen	C0030794	pelvic pain	1	[P11511]	DRUG	0.038585711
C10AB02	bezafibrate	C0149931	migraine	1	[P08684]	DRUG	0.06259756
S01EE01	latanoprost	C0004096	asthma	3	[Q13258, P43115, O94956]	DRUG	0.009279632
C08DB01	diltiazem	C0004093	asthenia	1	[P28223]	DRUG	0.043339606
J01XD02	tinidazole	C0020517	hypersensitivity	1	[P41595]	DRUG	0.019575297
N05BC01	meprobamate	C0015230	rash	8	[P07550, P01024, P26358, P28223, P08908, P31645, P50135, P09211]	METABOLITE	0.010218075
L02BB03	bicalutamide	C0021311	infection	2	[P03372, P04150]	DRUG	0.046132498
M01AH03	valdecoxib	C0020473	hyperlipidemia	1	[P23219]	DRUG_AND_METABOLITE	0.199911749
A02BC02	pantoprazole	C0027813	neuritis	1	[P08183]	DRUG_AND_METABOLITE	0.07627984
C09AA05	ramipril	C0003811	arrhythmia	1	[P12821]	DRUG	0.011557989
C01BD01	amiodarone	C0085610	sinus bradycardia	1	[Q14524]	DRUG	0.019028106
N02CC03	zolmitriptan	C0013595	eczema	1	[P08908]	DRUG	0.115394253
N06AA06	trimipramine	C0003123	anorexia	9	[P28223, P21917, P28335, P21397, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	3.39333E-07
C07AG02	carvedilol	C0003123	anorexia	1	[P31645]	DRUG_AND_METABOLITE	0.080482871
N05AB02	fluphenazine	C0009806	constipation	2	[P46098, P41595]	DRUG	0.003300583
L01XX05	hydroxyurea	C0009951	convulsions	1	[P14780]	METABOLITE	0.082841128
M01AH01	celecoxib	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.054359067
M01AB05	diclofenac	C0025290	aseptic meningitis	1	[P10145]	DRUG_AND_METABOLITE	0.069161939
P01AX06	atovaquone	C0019158	hepatitis	1	[P05181]	METABOLITE	0.331807079
G03HA01	cyproterone	C0023890	cirrhosis	1	[P08684]	DRUG	0.047186097
M01AB05	diclofenac	C0025289	meningitis	1	[P10145]	DRUG_AND_METABOLITE	0.089912296
L01BB02	mercaptopurine	C0032584	polyps	2	[P47989, O15440]	DRUG	0.324367411
L01BC06	capecitabine	C0015695	liver fatty	1	[P02768]	METABOLITE	0.09470362
N04BC04	ropinirole	C0037763	spasm	1	[P21918]	DRUG_AND_METABOLITE	0.045012311
D07AC04	fluocinolone acetonide	C0017601	glaucoma	1	[P04150]	DRUG	0.020153847
C03AA03	hydrochlorothiazide	C0009319	colitis	1	[P00918]	DRUG	0.153914336
N07XX02	riluzole	C0001339	acute pancreatitis	2	[Q99895, P04798]	DRUG	0.020730341
N03AB02	phenytoin	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.110888784
L04AX04	lenalidomide	C0012813	diverticulitis	1	[P01375]	DRUG	0.045033357
C10AA02	lovastatin	C0021311	infection	8	[P49327, P05362, P11413, P47989, P09601, Q13363, P09874, P07864]	METABOLITE	0.499995859
G03CA03	estradiol	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.114766442
N06AA06	trimipramine	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.169036837
N06AA09	amitriptyline	C0019158	hepatitis	4	[P05181, P23219, P11509, P02768]	DRUG_AND_METABOLITE	0.018143936
S01EE01	latanoprost	C0015230	rash	2	[P21731, Q13258]	DRUG_AND_METABOLITE	0.020237105
A05AA02	ursodeoxycholic acid	C0020538	hypertension	2	[Q13133, P11473]	METABOLITE	0.072023427
N06DA02	donepezil	C0013395	Dyspepsia	1	[P23219]	DRUG	0.019687894
M01AB05	diclofenac	C0003123	anorexia	5	[P28223, P21917, P28335, P28221, P14416]	DRUG	8.65131E-05
L01CB01	etoposide	C0006266	bronchospasm	1	[P33527]	DRUG_AND_METABOLITE	0.273043581
C10AB05	fenofibrate	C0020538	hypertension	3	[P37231, P11712, Q07869]	DRUG_AND_METABOLITE	0.013755114
N05AD01	haloperidol	C0018524	hallucinations	6	[P08183, P36544, P35498, Q99250, P04156, Q9NY46]	DRUG	0.000179486
C09CA01	losartan	C0011603	dermatitis	1	[Q07343]	DRUG	0.264470058
M01AH03	valdecoxib	C0020538	hypertension	8	[P35348, P21728, P31645, Q9Y2I1, P28223, P11712, P08913, P18089]	DRUG_AND_METABOLITE	0.002194013
L01XX05	hydroxyurea	C0013604	edema	1	[P14780]	METABOLITE	0.015405718
C09AA03	lisinopril	C0003811	arrhythmia	1	[P12821]	DRUG	0.013961737
M01AH03	valdecoxib	C0020517	hypersensitivity	4	[P41595, Q01959, P35367, P25021]	DRUG_AND_METABOLITE	0.001260561
A10BG03	pioglitazone	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.096910793
M01AE03	ketoprofen	C0013395	Dyspepsia	1	[P23219]	DRUG	0.025394378
C09AA08	cilazapril	C0033687	proteinuria	1	[P12821]	DRUG	0.019687894
N06AX21	duloxetine	C0014130	Endocrine Disorders	5	[Q12809, P32239, Q13639, P35354, P23219]	METABOLITE	0.093228225
C09CA01	losartan	C0031117	peripheral neuropathy	2	[P12821, P08183]	DRUG	0.002924243
M01AE09	flurbiprofen	C0042373	Vascular Disorders	1	[P10145]	DRUG	0.136554131
A07EC01	sulfasalazine	C0085605	hepatic failure	1	[O15111]	DRUG_AND_METABOLITE	0.046902683
N02AA03	hydromorphone	C0027051	myocardial infarction	4	[P21554, P11712, P31645, P23219]	DRUG	0.050945221
M01AE02	naproxen	C0027726	nephrotic syndrome	2	[P35354, P02768]	DRUG	0.210102959
N01AH01	fentanyl	C0018524	hallucinations	1	[P08183]	DRUG	0.082956716
N02AA03	hydromorphone	C0575081	abnormal gait	1	[P35498]	DRUG_AND_METABOLITE	0.049355201
L01XX35	anagrelide	C0004093	asthenia	1	[P28223]	METABOLITE	0.025953097
N03AX16	pregabalin	C0684249	lung cancer	2	[Q9NY47, Q01650]	DRUG	0.112311758
N06AB06	sertraline	C0030193	pain	1	[P11511]	METABOLITE	0.039009407
N01BB09	ropivacaine	C0242184	hypoxia	3	[P22460, Q14524, Q12809]	METABOLITE	0.072104339
L04AX02	thalidomide	C0011570	mental depression	5	[P33261, P42263, Q16099, Q16478, Q13003]	METABOLITE	0.001282425
N05AH04	quetiapine	C0085649	peripheral edema	1	[P08588]	DRUG	0.062610213
A03FA02	cisapride	C0019158	hepatitis	1	[P11509]	DRUG	0.14501301
N03AX14	levetiracetam	C0011991	diarrhea	1	[Q92887]	DRUG	0.021600815
R06AE07	cetirizine	C0020517	hypersensitivity	2	[P35367, Q9H3N8]	DRUG	0.000963004
C08DA01	verapamil	C0178428	sinus arrest	2	[Q14524, Q9Y3Q4]	DRUG	0.004163713
N06AX06	nefazodone	C0009319	colitis	5	[P08183, P31645, A5X5Y0, P46098, P41595]	METABOLITE	0.004120055
N04BC04	ropinirole	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.00183769
A02BC04	rabeprazole	C0025202	melanoma	3	[P08183, Q9UNQ0, P35354]	DRUG	0.364017733
M01AE02	naproxen	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.000963004
N06AX06	nefazodone	C0009324	ulcerative colitis	2	[P08183, P31645]	DRUG_AND_METABOLITE	0.115546177
N06DA02	donepezil	C0043144	wheezing	2	[P49682, P23219]	DRUG	0.054232974
L01BA01	methotrexate	C0008031	chest pain	1	[P02768]	DRUG	0.02223226
C05AA06	fluorometholone	C0017601	glaucoma	1	[P04150]	DRUG	0.020153847
G03DA04	progesterone	C0149741	nipple discharge	1	[P03372]	DRUG_AND_METABOLITE	0.094013826
A10BB09	gliclazide	C0018799	heart disease	2	[P15692, P11712]	DRUG	0.014025764
N06AB05	paroxetine	C0033975	psychosis	4	[P28223, P28222, P31645, P08908]	DRUG	0.000627876
N05CF02	zolpidem	C0021311	infection	1	[P23219]	DRUG	0.433263123
N06AB08	fluvoxamine	C0878544	cardiomyopathy	1	[P08588]	DRUG_AND_METABOLITE	0.127783868
L01XE02	gefitinib	C0042109	urticaria	1	[P43405]	DRUG_AND_METABOLITE	0.279072505
M01AB02	sulindac	C0015230	rash	4	[P37231, Q9Y5Y4, Q13258, Q07869]	METABOLITE	0.001735786
M01AB08	etodolac	C0023530	leukopenia	2	[P16662, O60656]	DRUG	0.003682386
C03BA08	metolazone	C0030305	pancreatitis	1	[P00918]	DRUG	0.120791799
C08DA01	verapamil	C0015230	rash	2	[P28223, P31645]	DRUG	0.15591646
L01XX11	estramustine	C0038454	cerebrovascular accident	1	[P03372]	DRUG_AND_METABOLITE	0.270466697
L04AX04	lenalidomide	C0878544	cardiomyopathy	1	[P01375]	DRUG	0.11345679
G03HA01	cyproterone	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.077274451
C08DB01	diltiazem	C0009319	colitis	2	[P08183, P46098]	DRUG	0.080458605
N06AA04	clomipramine	C0149931	migraine	7	[P29475, P28223, P21917, P31645, P35498, P08684, P28335]	DRUG_AND_METABOLITE	2.24958E-05
N06BA04	methylphenidate	C0020517	hypersensitivity	2	[P41595, Q01959]	DRUG_AND_METABOLITE	0.028343005
A04AA02	granisetron	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.003087195
A07EA06	budesonide	C0033975	psychosis	1	[P04150]	DRUG_AND_METABOLITE	0.140357948
C07AA06	timolol	C0006266	bronchospasm	1	[P07550]	DRUG	0.190102925
M01AG01	mefenamic acid	C0017152	gastritis	2	[P23219, P35354]	DRUG	0.003300583
M01AH01	celecoxib	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000256201
J05AE03	ritonavir	C0442874	neuropathy	1	[P08183]	DRUG	0.092835044
N03AF01	carbamazepine	C0428977	bradycardia	1	[Q14524]	DRUG	0.020983013
N03AG01	valproic acid	C0009088	cluster headache	1	[P08684]	DRUG	0.116487562
C03DB01	amiloride	C0009806	constipation	2	[P46098, P31645]	DRUG	0.003749697
A02BC03	lansoprazole	C0009324	ulcerative colitis	1	[P08183]	DRUG_AND_METABOLITE	0.203641648
C09AA09	fosinopril	C0013404	dyspnea	1	[P12821]	DRUG	0.014460868
N06BA04	methylphenidate	C0020538	hypertension	7	[P35348, P21728, P31645, P28223, P23975, P08913, P18089]	DRUG_AND_METABOLITE	0.001411627
L04AX02	thalidomide	C0243026	sepsis	1	[P01375]	DRUG	0.387887624
A10BB09	gliclazide	C0002871	anemia	2	[P15692, P02768]	DRUG	0.001595185
N06AA04	clomipramine	C0009319	colitis	5	[P08183, P31645, Q9H015, P46098, P41595]	DRUG_AND_METABOLITE	0.065368111
A02BC03	lansoprazole	C0009319	colitis	1	[P08183]	DRUG_AND_METABOLITE	0.212730719
N06AB08	fluvoxamine	C0002874	aplastic anemia	1	[P04798]	DRUG_AND_METABOLITE	0.121673094
B01AC07	dipyridamole	C0030193	pain	1	[Q08499]	DRUG	0.027162705
J01MA02	ciprofloxacin	C0037763	spasm	1	[P14867]	DRUG	0.030183251
N03AF01	carbamazepine	C0021311	infection	3	[P04156, P35354, P23219]	METABOLITE	0.213203897
H02AB07	prednisone	C0017601	glaucoma	1	[P04150]	DRUG_AND_METABOLITE	0.077866045
C02CA04	doxazosin	C0038454	cerebrovascular accident	1	[P28223]	METABOLITE	0.166969633
N05AA01	chlorpromazine	C0023895	liver disease	1	[P08684]	DRUG_AND_METABOLITE	0.433819359
A02BC04	rabeprazole	C0002871	anemia	1	[P02768]	DRUG_AND_METABOLITE	0.155477655
N05AA01	chlorpromazine	C0023890	cirrhosis	5	[P08684, P05181, P21554, P20701, P05362]	METABOLITE	0.076200799
N06AF03	phenelzine	C0009806	constipation	1	[P31645]	DRUG	0.030408848
L04AA06	mycophenolic acid	C0024299	lymphoma	1	[P37231]	DRUG_AND_METABOLITE	0.100990451
N03AX16	pregabalin	C0149931	migraine	1	[O00555]	DRUG	0.043989678
M05BA03	pamidronate	C0022660	acute renal failure	1	[P00492]	DRUG	0.016169699
N05CD02	nitrazepam	C0033975	psychosis	6	[P35462, P28223, P21917, P28222, P31645, P08908]	DRUG	7.83504E-05
N03AX09	lamotrigine	C0575081	abnormal gait	1	[P35498]	DRUG	0.028343005
A02BB01	misoprostol	C0015230	rash	4	[P21731, Q9Y5Y4, Q13258, Q07869]	METABOLITE	0.000286831
M04AB01	probenecid	C0011603	dermatitis	1	[O95255]	DRUG	0.281500942
J05AG01	nevirapine	C0019163	hepatitis B	1	[P11509]	DRUG	0.091830722
M01AE09	flurbiprofen	C0030305	pancreatitis	2	[P07858, P35354]	DRUG_AND_METABOLITE	0.042381513
A08AB01	orlistat	C0041912	upper respiratory tract infection	1	[P49327]	DRUG	0.295414647
R01AD01	beclomethasone	C1260880	rhinorrhea	1	[P35228]	DRUG_AND_METABOLITE	0.096593322
J05AG01	nevirapine	C0019158	hepatitis	1	[P11509]	DRUG	0.063596471
J05AG01	nevirapine	C0019159	hepatitis infectious	1	[P11509]	DRUG	0.063596471
M01AE01	ibuprofen	C0032285	pneumonia	2	[P10145, P35354]	DRUG	0.093228225
C07AB07	bisoprolol	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	9.09152E-05
M04AA01	allopurinol	C0002878	hemolytic anemia	1	[P00568]	METABOLITE	0.16044594
N06AA10	nortriptyline	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.086327305
A07EC01	sulfasalazine	C0085786	fibrosing alveolitis	2	[P05230, P37231]	DRUG_AND_METABOLITE	0.027162705
A07EA06	budesonide	C0221247	avascular necrosis	1	[P08183]	METABOLITE	0.073076437
A02BC04	rabeprazole	C0010054	coronary artery disease	4	[P08684, P35354, P02768, P04798]	DRUG_AND_METABOLITE	0.037092814
D05BB02	acitretin	C0013395	Dyspepsia	1	[P23219]	METABOLITE	0.03201379
C01DA02	nitroglycerin	C0042373	Vascular Disorders	1	[P37173]	METABOLITE	0.103621946
C09AA05	ramipril	C0042109	urticaria	1	[P12821]	DRUG	0.015087595
M01AE02	naproxen	C0010054	coronary artery disease	4	[P35354, P02768, P21554, Q8WW43]	DRUG	0.063186267
N06BA01	amphetamine	C0013395	Dyspepsia	1	[P14174]	METABOLITE	0.076374275
N06DA02	donepezil	C0013595	eczema	1	[P28223]	DRUG	0.115394253
N04BC04	ropinirole	C0007097	carcinoma	3	[P07550, P08684, P05177]	DRUG	0.497666338
N06BA01	amphetamine	C0013384	dyskinesia	3	[P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.023730722
C09AA08	cilazapril	C0027947	neutropenia	1	[P08183]	DRUG	0.019687894
N02AA03	hydromorphone	C0027651	tumor	12	[P08684, P21964, P08183, Q99720, P20815, P10632, P23219, P01189, Q12809, P23975, P21554, P35348]	METABOLITE	0.38361373
R03AC12	salmeterol	C0699744	ear infection	1	[P07550]	DRUG	0.212730719
M01AE02	naproxen	C0042109	urticaria	1	[P09917]	DRUG	0.103034195
A08AB01	orlistat	C0006266	bronchospasm	1	[Q13093]	DRUG	0.190102925
M01AE02	naproxen	C0027051	myocardial infarction	10	[P35354, P02768, P21554, Q8WW43, P08246, P11712, P31645, P23219, P05177, P18089]	DRUG	0.000963004
N06AA17	amoxapine	C0042109	urticaria	1	[P07550]	METABOLITE	0.090245404
L02BA01	tamoxifen	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.147941146
N06BA09	atomoxetine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.007907224
M01AH01	celecoxib	C0037287	skin nodule	4	[P21554, P35354, P34972, Q16539]	DRUG	0.001855509
N06AA04	clomipramine	C0011849	diabetes mellitus	9	[P06276, P11712, P09211, O15245, P08684, P02768, P18089, P13945, P07550]	DRUG_AND_METABOLITE	0.029637746
N06AB04	citalopram	C0027051	myocardial infarction	4	[P33261, P31645, P05177, P08588]	DRUG	0.02890613
M01AG01	mefenamic acid	C0033687	proteinuria	1	[P08235]	METABOLITE	0.035047926
L01XE03	erlotinib	C0038454	cerebrovascular accident	2	[P24723, O60674]	DRUG_AND_METABOLITE	0.481001398
N06BA01	amphetamine	C0013404	dyspnea	1	[P14174]	METABOLITE	0.133758529
N04BD01	selegiline	C0027051	myocardial infarction	6	[P11712, P33261, P31645, P05177, P08588, P18089]	METABOLITE	0.013399503
C09AA03	lisinopril	C0039231	tachycardia	1	[P12821]	DRUG	0.00976001
N06AX06	nefazodone	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.002877124
L01BA01	methotrexate	C0030305	pancreatitis	1	[P42898]	DRUG	0.179324562
D04AA32	diphenhydramine	C0009951	convulsions	3	[P35498, Q99250, Q9NY46]	DRUG	0.016701405
D01AC08	ketoconazole	C0030193	pain	1	[P11511]	DRUG	0.042804682
R03AC02	salbutamol	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.14501301
N02AA03	hydromorphone	C0004134	ataxia	1	[P35498]	DRUG_AND_METABOLITE	0.10852861
J01FA10	azithromycin	C0019158	hepatitis	1	[P11509]	DRUG_AND_METABOLITE	0.091184812
L01XX35	anagrelide	C0015230	rash	2	[P28223, P08908]	METABOLITE	0.028123725
M01AE01	ibuprofen	C0025309	meningoencephalitis	1	[P10145]	DRUG	0.140089359
N01AH01	fentanyl	C0018790	cardiac arrest	1	[Q12809]	DRUG	0.046871884
N01AH01	fentanyl	C0018799	heart disease	2	[Q12809, P41595]	DRUG	0.06351216
H02AB06	prednisolone	C0021311	infection	2	[P03372, P04150]	DRUG_AND_METABOLITE	0.29910529
N02CC01	sumatriptan	C0699744	ear infection	2	[P07550, P03372]	METABOLITE	0.439089979
J05AF02	didanosine	C0020565	breast enlargement	1	[P54098]	METABOLITE	0.100645764
N05BE01	buspirone	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.02477419
C10AB04	gemfibrozil	C0008325	cholecystitis	1	[P37231]	DRUG	0.029637746
G03BA02	methyltestosterone	C0022346	jaundice	3	[Q9Y6L6, P22309, P11413]	DRUG_AND_METABOLITE	0.000178986
C09CA01	losartan	C0011991	diarrhea	1	[P16662]	DRUG	0.048951084
M01AB15	ketorolac	C0013395	Dyspepsia	1	[P23219]	DRUG	0.025394378
L02AB01	megestrol	C0023530	leukopenia	1	[P08183]	DRUG	0.036486436
L01XX35	anagrelide	C0027051	myocardial infarction	2	[Q9H244, P05177]	DRUG	0.072027513
B01AC07	dipyridamole	C0151827	eye pain	1	[Q08499]	DRUG	0.037934867
N04BX01	tolcapone	C0033975	psychosis	1	[P21964]	DRUG	0.070518569
L01XE02	gefitinib	C0042373	Vascular Disorders	3	[P37023, P36897, P37173]	DRUG_AND_METABOLITE	0.249802504
C09AA01	captopril	C0042109	urticaria	1	[P12821]	DRUG	0.05003687
N05AX12	aripiprazole	C0231528	myalgia	1	[P17252]	DRUG_AND_METABOLITE	0.199608332
A02BA02	ranitidine	C0018524	hallucinations	1	[P08183]	DRUG	0.085892844
R06AB04	chlorpheniramine	C0009806	constipation	2	[P41595, P31645]	DRUG	0.002043067
C09XA02	aliskiren	C0006826	cancer	2	[P08684, P07339]	DRUG_AND_METABOLITE	0.214653855
C03BA08	metolazone	C0030552	weakness	1	[P55017]	DRUG	0.023643559
L01XE02	gefitinib	C0021311	infection	25	[P42336, P00533, P23458, P00519, Q13546, P19525, P08631, Q02156, P43405, P78362, Q96SB4, P04049, P16234, Q13153, P04629, P49771, P31749, Q14164, P28482, O43353, Q16539, P27361, Q04759, P36897, P37173]	DRUG_AND_METABOLITE	0.128073342
G03XA01	danazol	C0007286	carpal tunnel syndrome	2	[P06401, P03372]	DRUG_AND_METABOLITE	0.000590875
N04BD01	selegiline	C0039231	tachycardia	1	[P08588]	METABOLITE	0.044087091
J05AE07	fosamprenavir	C0027947	neutropenia	1	[P08183]	METABOLITE	0.039009407
L04AX02	thalidomide	C0011849	diabetes mellitus	5	[P01375, P11712, P19838, P35354, P21980]	METABOLITE	0.204160347
N06AX11	mirtazapine	C0011849	diabetes mellitus	4	[P11712, P08684, P18089, P10632]	DRUG	0.03763883
C01BA02	procainamide	C0018801	heart failure	2	[Q14524, Q12809]	DRUG_AND_METABOLITE	0.014006139
G04BE03	sildenafil	C0231218	malaise	1	[Q08499]	DRUG	0.022963468
N06AA04	clomipramine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.133669143
N06AB03	fluoxetine	C0011991	diarrhea	1	[P46098]	DRUG	0.07797371
C09AA03	lisinopril	C0027947	neutropenia	1	[P08183]	DRUG	0.019687894
J01MA01	ofloxacin	C0020538	hypertension	1	[O15244]	DRUG	0.258878236
M01AX01	nabumetone	C0038358	gastric ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.000772249
N04BC05	pramipexole	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG	0
L01XE03	erlotinib	C0030305	pancreatitis	1	[P15056]	DRUG_AND_METABOLITE	0.486866165
S01AA14	penicillin G	C0442874	neuropathy	2	[Q9UQD0, P08183]	METABOLITE	0.05126256
N02AA03	hydromorphone	C0004096	asthma	1	[P23219]	DRUG	0.369658864
N02AA03	hydromorphone	C0004093	asthenia	1	[P31645]	METABOLITE	0.049355201
R03AC12	salmeterol	C0020538	hypertension	4	[P20815, P13945, P07550, P08588]	DRUG	0.000301591
C08CA05	nifedipine	C0011991	diarrhea	2	[P46098, Q92887]	DRUG	0.010512491
A05AA02	ursodeoxycholic acid	C0032584	polyps	2	[Q92887, P05181]	DRUG_AND_METABOLITE	0.362617296
A02BA03	famotidine	C0020517	hypersensitivity	2	[P25021, Q9H3N8]	DRUG	0.001434055
R06AD02	promethazine	C0023530	leukopenia	1	[P08183]	DRUG	0.109863158
N02CC05	almotriptan	C0010054	coronary artery disease	1	[P08684]	DRUG	0.087023603
L01XE01	imatinib	C0033860	psoriasis	6	[P28482, P31749, P27361, P00918, O75582, P35916]	DRUG	0.204402915
C09AA03	lisinopril	C0042373	Vascular Disorders	1	[P12821]	DRUG	0.039025321
G03AC06	medroxyprogesterone	C0242422	Parkinson	1	[P08183]	DRUG_AND_METABOLITE	0.117843433
N06AB03	fluoxetine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.006542074
N06AB03	fluoxetine	C0004096	asthma	3	[P11229, P20309, Q08499]	METABOLITE	0.15591646
M01AG01	mefenamic acid	C0021311	infection	2	[P35354, P23219]	DRUG	0.106277208
H02AB02	dexamethasone	C0878544	cardiomyopathy	1	[P03956]	METABOLITE	0.180739032
N03AX09	lamotrigine	C0014549	grand mal	2	[Q99250, P35498]	DRUG	0.003200919
C09AA08	cilazapril	C0015672	fatigue	1	[P12821]	DRUG	0.012425662
C09AA03	lisinopril	C0007859	neck pain	1	[P12821]	DRUG	0.006405429
S01ED04	metipranolol	C0015230	rash	2	[P07550, P08908]	METABOLITE	0.003201423
L01XE01	imatinib	C0022658	nephropathy	6	[P00533, P02768, P00915, P00918, Q05397, P23219]	DRUG	0.066908513
C09AA10	trandolapril	C0015672	fatigue	1	[P12821]	DRUG_AND_METABOLITE	0.012425662
N06AA02	imipramine	C0038454	cerebrovascular accident	3	[P05362, P28223, P07550]	DRUG_AND_METABOLITE	0.204160347
C09AA01	captopril	C0262398	bullous pemphigus	1	[P14780]	DRUG	0.040753047
N06AX11	mirtazapine	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.006247349
N06DA03	rivastigmine	C0149931	migraine	2	[P31645, P08684]	DRUG	0.001881731
C03DA01	spironolactone	C0018418	gynecomastia	1	[P11511]	METABOLITE	0.011557989
C01BC03	propafenone	C0009806	constipation	1	[Q14524]	DRUG	0.023338897
N06AB06	sertraline	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.030522168
N06AX16	venlafaxine	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.218869626
N03AG06	tiagabine	C0018524	hallucinations	1	[Q99259]	DRUG	0.120607843
C10AB05	fenofibrate	C0013295	duodenal ulcer	1	[P37231]	DRUG_AND_METABOLITE	0.036928011
D05BB02	acitretin	C0013595	eczema	2	[P21731, Q13258]	METABOLITE	0.057974285
C01BD01	amiodarone	C0024115	lung disorder	3	[P08183, P04798, P05177]	DRUG	0.036120827
G04BE03	sildenafil	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.064721996
L04AA06	mycophenolic acid	C0024115	lung disorder	1	[P22309]	DRUG_AND_METABOLITE	0.092356341
N06AX16	venlafaxine	C0242184	hypoxia	4	[P08172, P11229, Q12791, Q14524]	METABOLITE	0.195610485
A07EA06	budesonide	C0004093	asthenia	4	[P08185, P35354, P04150, P35228]	METABOLITE	3.83447E-06
M01AE02	naproxen	C0149931	migraine	4	[P28223, P21917, P31645, P28335]	DRUG	0.001106422
R03AC13	formoterol	C0019080	hemorrhage	1	[P11712]	DRUG	0.034424934
N06AB03	fluoxetine	C0011849	diabetes mellitus	4	[P15121, P11712, P08684, P18089]	DRUG	0.07880264
N05CF03	zaleplon	C0029456	osteoporosis	1	[P08684]	DRUG	0.076416917
J01AA08	minocycline	C0004096	asthma	5	[P09917, P14780, P15692, P08253, P01584]	DRUG	0.003335247
D01AE15	terbinafine	C0023895	liver disease	1	[P08684]	DRUG	0.113271913
J05AE03	ritonavir	C0024115	lung disorder	3	[P08183, P05181, P05177]	DRUG	0.022963468
M03BX08	cyclobenzaprine	C0575081	abnormal gait	1	[P35498]	DRUG_AND_METABOLITE	0.094536423
S01AA14	penicillin G	C0003811	arrhythmia	1	[Q14524]	DRUG	0.071241753
N05CF02	zolpidem	C0006266	bronchospasm	1	[P23219]	DRUG	0.301578738
G03BA02	methyltestosterone	C0019080	hemorrhage	1	[P11712]	METABOLITE	0.179584572
N05AH04	quetiapine	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG_AND_METABOLITE	0.001041147
L04AX04	lenalidomide	C0017152	gastritis	4	[P01375, P23219, P35354, P19838]	DRUG	2.86494E-05
L04AX04	lenalidomide	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.045033357
N06AX05	trazodone	C0027051	myocardial infarction	6	[P21554, P07550, P03956, P31645, P08588, P18089]	DRUG_AND_METABOLITE	0.046584723
N06AB06	sertraline	C0027051	myocardial infarction	7	[P10275, P11712, P33261, P31645, P05177, P08588, P18089]	DRUG	0.00165768
L04AX04	lenalidomide	C0041912	upper respiratory tract infection	4	[P01375, P19838, P35354, P23219]	DRUG	0.040753047
N06AA11	protriptyline	C0042109	urticaria	1	[P07550]	DRUG	0.110876596
N02AA03	hydromorphone	C0015672	fatigue	1	[P31645]	METABOLITE	0.049355201
L04AX01	azathioprine	C0025202	melanoma	6	[P16220, Q16539, Q02750, P17252, Q13126, P27361]	METABOLITE	0.198594618
L04AA13	leflunomide	C0041912	upper respiratory tract infection	1	[P09917]	DRUG	0.30867782
A10BG02	rosiglitazone	C0041912	upper respiratory tract infection	3	[P23219, P37231, Q07869]	DRUG	0.082841128
N05AC02	thioridazine	C0242422	Parkinson	10	[P21917, P05181, Q01959, P21554, P50406, P08908, P31645, Q9UQD0, P14416, P35462]	DRUG_AND_METABOLITE	1.54047E-05
M03BX08	cyclobenzaprine	C0018524	hallucinations	6	[P08183, P36544, P35498, Q99250, P04156, Q9NY46]	DRUG_AND_METABOLITE	0.000374019
N05AC02	thioridazine	C0686347	tardive dyskinesia	1	[P35498]	DRUG	0.073573636
C10AB05	fenofibrate	C0010709	cyst	3	[Q07869, P37231, Q03181]	METABOLITE	0.165683013
J01MA02	ciprofloxacin	C0018524	hallucinations	1	[P08183]	DRUG	0.076656655
N04BD01	selegiline	C1458155	breast neoplasm	11	[P08684, P08183, Q99720, P05181, P05177, P20813, Q01959, P11509, Q05940, P23975, P07477]	METABOLITE	0.293285351
N06DA02	donepezil	C0007784	cerebral hemorrhage	2	[P05067, P28223]	DRUG	0.022470221
M01AH02	rofecoxib	C0018944	hematoma	1	[P11712]	DRUG_AND_METABOLITE	0.113271913
N02AA01	morphine	C0162297	respiratory arrest	1	[Q9UQD0]	DRUG_AND_METABOLITE	0.069031215
G04BE03	sildenafil	C0037011	shoulder pain	1	[Q08499]	DRUG	0.022963468
C01BA01	quinidine	C0428977	bradycardia	1	[Q14524]	DRUG	0.028717627
N06AX16	venlafaxine	C0004238	atrial fibrillation	1	[Q14524]	METABOLITE	0.221561666
L01BA01	methotrexate	C0042384	vasculitis	1	[Q96J66]	DRUG	0.07026785
M01AE02	naproxen	C1458155	breast neoplasm	17	[P35354, P42330, P33527, P22309, Q99720, P63000, P18031, P46721, P05177, P07858, P60953, P49810, P09917, Q9Y618, Q01959, P23975, P41222]	DRUG	0.260548066
L02BA01	tamoxifen	C0006826	cancer	19	[P35354, P08183, P17252, P03372, Q92731, Q13393, Q9UNQ0, P20815, P05181, P10632, P04798, P08684, P10275, P11511, P23219, P05177, P05771, P11509, Q16678]	DRUG	0.001536633
C07AB03	atenolol	C0018801	heart failure	1	[P07550]	DRUG	0.070407486
C07AB03	atenolol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.070407486
C09AA04	perindopril	C0267406	mesenteric infarction	1	[P12821]	DRUG_AND_METABOLITE	0.063596471
N03AB02	phenytoin	C0243026	sepsis	1	[O00408]	METABOLITE	0.226047336
C09AA02	enalapril	C0035078	renal failure	3	[P12821, P08183, P00797]	METABOLITE	0.000299598
L04AA13	leflunomide	C0004096	asthma	2	[P09917, P03956]	DRUG	0.059662382
N02CC01	sumatriptan	C0013146	abuse	1	[P41595]	DRUG	0.034547486
N06AB03	fluoxetine	C0024236	lymphedema	1	[P08684]	DRUG	0.05003687
M01AB15	ketorolac	C0041582	ulcer	1	[P10145]	DRUG	0.035667691
C07AB02	metoprolol	C0011570	mental depression	3	[P33261, P28222, P08908]	DRUG_AND_METABOLITE	0.000345126
N06AA01	desipramine	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.062776404
A02BC02	pantoprazole	C0041912	upper respiratory tract infection	1	[P08575]	METABOLITE	0.429857961
N05AB06	trifluoperazine	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.249014435
C07AG02	carvedilol	C0018681	headache	1	[P19320]	DRUG	0.044396476
L02BA01	tamoxifen	C0038454	cerebrovascular accident	2	[P03372, P35354]	DRUG	0.095256162
D01AE15	terbinafine	C0041912	upper respiratory tract infection	1	[P23219]	DRUG	0.344371637
R06AD02	promethazine	C0039231	tachycardia	1	[P08588]	DRUG	0.045864418
D05BB02	acitretin	C0019348	herpes simplex	2	[P35408, P43116]	METABOLITE	0.019839873
N06AA12	doxepin	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.060491189
N06AX05	trazodone	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.03490134
C07AG02	carvedilol	C0149931	migraine	3	[P19320, P31645, P08684]	DRUG	0.000905071
A03FA02	cisapride	C0149931	migraine	3	[P28223, P08684, P28335]	DRUG	0.002795416
J01EC02	sulfadiazine	C0011570	mental depression	1	[P08684]	DRUG	0.051348531
L04AX04	lenalidomide	C0018802	congestive heart failure	1	[P01375]	DRUG	0.096973815
L04AX04	lenalidomide	C0018801	heart failure	1	[P01375]	DRUG	0.096973815
N05AX12	aripiprazole	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.008738741
C09AA10	trandolapril	C0009782	connective tissue disorders	1	[P12821]	DRUG_AND_METABOLITE	0.010569187
C01BC04	flecainide	C0018802	congestive heart failure	2	[Q14524, Q12809]	DRUG	0.006542074
L04AX04	lenalidomide	C0018944	hematoma	1	[P11712]	DRUG	0.060772541
N02AA01	morphine	C0035078	renal failure	1	[P08183]	DRUG_AND_METABOLITE	0.132070031
C09AA01	captopril	C0002871	anemia	1	[P02768]	DRUG	0.088488982
N06AX11	mirtazapine	C0009806	constipation	3	[A5X5Y0, P46098, P31645]	DRUG	7.87958E-05
C09CA01	losartan	C0021311	infection	2	[P50052, P12821]	DRUG	0.29910529
J01MA06	norfloxacin	C0030305	pancreatitis	1	[P04798]	DRUG	0.103777387
N05AB06	trifluoperazine	C0010200	cough	1	[Q8NER1]	DRUG	0.057987175
A02BC01	omeprazole	C0020517	hypersensitivity	2	[Q8NER1, P25021]	DRUG_AND_METABOLITE	0.021588518
G03AC06	medroxyprogesterone	C1458155	breast neoplasm	7	[P08684, P03372, P08183, P06401, P08235, P10275, P04150]	DRUG_AND_METABOLITE	0.009016772
C04AD03	pentoxifylline	C0231218	malaise	1	[Q08499]	DRUG	0.012309865
N06AX21	duloxetine	C0018802	congestive heart failure	4	[Q9Y2I1, Q12809, P07550, O43306]	DRUG	0.01690995
N06AX21	duloxetine	C0018801	heart failure	4	[Q9Y2I1, Q12809, P07550, O43306]	DRUG	0.01690995
N06AB03	fluoxetine	C0009319	colitis	4	[P08183, P31645, P46098, P41595]	DRUG_AND_METABOLITE	0.024208166
L04AX04	lenalidomide	C0018995	hemochromatosis	1	[P01375]	DRUG	0.060772541
M01AH02	rofecoxib	C0018802	congestive heart failure	1	[Q9Y2I1]	DRUG_AND_METABOLITE	0.185493577
L01XX05	hydroxyurea	C0015230	rash	1	[P14780]	METABOLITE	0.086440059
G03DA04	progesterone	C0030193	pain	1	[P11511]	DRUG_AND_METABOLITE	0.075413212
M01AE09	flurbiprofen	C0034065	pulmonary embolism	1	[P02768]	DRUG	0.042475697
L04AX02	thalidomide	C0085576	microcytic anemia	1	[P01375]	DRUG	0.266015619
A10BB09	gliclazide	C0022658	nephropathy	1	[P02768]	DRUG	0.047374915
N06AX16	venlafaxine	C0004134	ataxia	2	[P35498, Q14643]	DRUG	0.0576214
A10BB02	chlorpropamide	C0020615	hypoglycemia	2	[P09467, Q09428]	DRUG	0.014572723
N07BB04	naltrexone	C0018524	hallucinations	2	[P08183, P36544]	DRUG	0.008593584
M01AH02	rofecoxib	C0018834	heartburn	1	[P23219]	DRUG_AND_METABOLITE	0.049477114
C01BC04	flecainide	C0018790	cardiac arrest	2	[Q14524, Q12809]	DRUG	0.001465281
N06AX21	duloxetine	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.010925599
V03AF03	leucovorin	C0011991	diarrhea	1	[Q92887]	DRUG_AND_METABOLITE	0.028748417
A10BB09	gliclazide	C0006277	bronchitis	1	[P15692]	DRUG	0.011339904
N02CC01	sumatriptan	C0149741	nipple discharge	1	[P03372]	METABOLITE	0.060203322
J05AE01	saquinavir	C0030354	papilloma	5	[P08183, Q92887, P33527, Q9UNQ0, P20815]	DRUG	0.146298288
N05BA12	alprazolam	C0001969	drunk	1	[P47869]	DRUG	0.073960049
N06AA21	maprotiline	C0020538	hypertension	5	[P35348, P21728, P31645, P28223, P23975]	DRUG_AND_METABOLITE	0.002159593
N05AH02	clozapine	C0011603	dermatitis	5	[P07550, P21731, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.064448325
A10BB09	gliclazide	C0022660	acute renal failure	1	[P15692]	DRUG	0.018638775
M01AH02	rofecoxib	C0014544	epilepsy	1	[P33527]	DRUG_AND_METABOLITE	0.20366535
A02BC04	rabeprazole	C0024115	lung disorder	4	[P08183, P35354, P04798, P05177]	DRUG_AND_METABOLITE	0.044087091
A07DA03	loperamide	C1527304	allergic reaction	2	[P35367, P25021]	METABOLITE	0.010731647
N02CC06	eletriptan	C0015230	rash	1	[P08908]	DRUG	0.134281172
N05AX12	aripiprazole	C0009319	colitis	4	[P31645, A5X5Y0, P46098, P41595]	DRUG_AND_METABOLITE	0.035837799
G03BA03	testosterone	C0042755	Masculinization	1	[P37058]	DRUG_AND_METABOLITE	0.021169216
C03DA01	spironolactone	C0678222	breast cancer	13	[P11511, P03372, P08183, P06401, Q92887, P08235, P14060, P05093, P46721, P10275, P04150, P10632, P18405]	METABOLITE	0.000145253
C01AA05	digoxin	C0018524	hallucinations	2	[P08183, P50993]	DRUG_AND_METABOLITE	0.019161185
N05AX12	aripiprazole	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
M01AE01	ibuprofen	C0004238	atrial fibrillation	1	[P10145]	DRUG	0.219824681
N06AX21	duloxetine	C0023530	leukopenia	1	[P08183]	DRUG	0.199065581
J01MA01	ofloxacin	C0085584	encephalopathy	2	[P14867, P08183]	DRUG	0.012233731
G03CA03	estradiol	C1378703	kidney carcinoma	16	[P32239, P08183, P33527, P21964, P03372, Q92731, P11474, O15438, Q9UNQ0, P20815, P05181, P10632, P04798, P08684, P10275, P05177]	DRUG_AND_METABOLITE	0.105349
N04BC05	pramipexole	C0010709	cyst	1	[P23975]	DRUG	0.499995859
L01XE01	imatinib	C0085605	hepatic failure	1	[P17948]	DRUG	0.21810323
N05AX08	risperidone	C0007820	cerebrovascular disorder	3	[P21731, P28223, P07550]	DRUG_AND_METABOLITE	0.100012956
N02CA01	dihydroergotamine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.008079398
A02BC01	omeprazole	C0020538	hypertension	3	[P05026, P05023, P11712]	DRUG_AND_METABOLITE	0.072738991
G03DA04	progesterone	C0001339	acute pancreatitis	2	[P05181, P04798]	DRUG_AND_METABOLITE	0.174370945
N05AH02	clozapine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.008050452
N06AX21	duloxetine	C0006325	bruxism	1	[P31645]	DRUG_AND_METABOLITE	0.036871472
M01AH01	celecoxib	C0007820	cerebrovascular disorder	2	[P28223, P35354]	DRUG_AND_METABOLITE	0.192432613
N02AE01	buprenorphine	C0018524	hallucinations	1	[P08183]	DRUG	0.099690737
N04BX01	tolcapone	C0003850	arteriosclerosis	1	[P11712]	DRUG	0.235785139
J01AA02	doxycycline	C0031090	periodontal disease	1	[P45452]	DRUG	0.057987175
N06AX21	duloxetine	C0018799	heart disease	8	[Q12809, P23219, P31645, P35354, P08588, P07550, Q13639, P41595]	DRUG_AND_METABOLITE	0.017783546
N04BX01	tolcapone	C0003864	arthritis	1	[P27487]	METABOLITE	0.093555819
N03AX12	gabapentin	C0010709	cyst	1	[Q01650]	DRUG_AND_METABOLITE	0.41943705
N05AX12	aripiprazole	C0011206	delirium	1	[P21554]	DRUG_AND_METABOLITE	0.070518569
M01AE12	oxaprozin	C0032285	pneumonia	1	[P35354]	DRUG	0.045375219
A02BC04	rabeprazole	C0003873	rheumatoid arthritis	7	[P35354, P23219, P05177, P05023, P47712, Q16647, P04798]	DRUG_AND_METABOLITE	0.020105789
A11CC04	calcitriol	C0020538	hypertension	1	[P11473]	DRUG_AND_METABOLITE	0.092998912
N05BA01	diazepam	C0013395	Dyspepsia	1	[P23219]	DRUG	0.047761265
L01XE01	imatinib	C0019348	herpes simplex	2	[P19525, P04626]	DRUG	0.324188139
C10AB02	bezafibrate	C0027051	myocardial infarction	3	[P37231, P04798, Q07869]	DRUG	0.029660789
C01BA01	quinidine	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.169250637
M01AB02	sulindac	C0018802	congestive heart failure	1	[P37231]	DRUG_AND_METABOLITE	0.100095257
J05AE03	ritonavir	C0025202	melanoma	2	[P08183, Q9UNQ0]	DRUG	0.232525982
L02AB01	megestrol	C0004093	asthenia	1	[P04150]	DRUG	0.019239124
M01AB05	diclofenac	C0038454	cerebrovascular accident	2	[P28223, P35354]	DRUG_AND_METABOLITE	0.154590561
C04AD03	pentoxifylline	C0231528	myalgia	1	[Q08499]	DRUG	0.069711729
A02BC03	lansoprazole	C0007097	carcinoma	7	[P08183, Q9UNQ0, Q16678, P10632, P04798, P08684, P05177]	DRUG_AND_METABOLITE	0.257746653
G03BA03	testosterone	C0151950	deep thrombophlebitis	2	[P03372, Q92731]	METABOLITE	0.080458605
N05AE04	ziprasidone	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.009457734
C10AA04	fluvastatin	C0019158	hepatitis	1	[O14684]	METABOLITE	0.078558694
H02AB02	dexamethasone	C0152459	striae	1	[P35354]	DRUG_AND_METABOLITE	0.141393007
C07AB02	metoprolol	C0011849	diabetes mellitus	2	[P13945, P07550]	DRUG_AND_METABOLITE	0.070920127
N03AX16	pregabalin	C0018524	hallucinations	1	[O00555]	DRUG	0.054931462
N04BD01	selegiline	C0009951	convulsions	3	[P08183, P08908, P31645]	METABOLITE	0.037700893
L04AX04	lenalidomide	C0020676	hypothyroidism	1	[P01375]	DRUG	0.063596471
R03BA08	ciclesonide	C0015672	fatigue	2	[P08185, P04150]	DRUG	0.000161903
A10BX02	repaglinide	C0027051	myocardial infarction	1	[P37231]	DRUG	0.147275497
C08DB01	diltiazem	C0023530	leukopenia	1	[P08183]	DRUG	0.083416405
D07AC13	mometasone	C0015672	fatigue	1	[P04150]	METABOLITE	0.010207101
M01AB05	diclofenac	C0009324	ulcerative colitis	4	[P10145, P08183, P00918, P35354]	DRUG_AND_METABOLITE	0.029203738
N07XX02	riluzole	C0027651	tumor	5	[Q9UNQ0, P04798, P05177, Q14524, O15554]	DRUG	0.386758185
N02CC01	sumatriptan	C0013390	dysmenorrhea	1	[P04798]	METABOLITE	0.028717627
N06DA02	donepezil	C0019158	hepatitis	1	[P23219]	DRUG	0.067564802
C08DB01	diltiazem	C1527304	allergic reaction	1	[P35367]	DRUG	0.086884165
N06AX21	duloxetine	C0011991	diarrhea	1	[P46098]	DRUG	0.124383228
M01AB05	diclofenac	C0009319	colitis	6	[P10145, P08183, P00918, P35354, P46098, P41595]	DRUG	0.003293293
D05BB02	acitretin	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG_AND_METABOLITE	0.002782021
C07AG02	carvedilol	C0020456	hyperglycemia	1	[Q9Y210]	DRUG	0.094459097
J05AE03	ritonavir	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.091808164
N06AB05	paroxetine	C0007097	carcinoma	4	[P08183, P10632, Q9UBN4, P23975]	DRUG_AND_METABOLITE	0.499499939
N06AB03	fluoxetine	C0031212	personality disorder	1	[P31645]	DRUG_AND_METABOLITE	0.035667691
R06AX26	fexofenadine	C0020517	hypersensitivity	2	[P35367, Q9H3N8]	DRUG	0.003087195
B01AC05	ticlopidine	C0003123	anorexia	1	[P14416]	METABOLITE	0.086416771
D07AB10	alclometasone	C0011603	dermatitis	1	[P47712]	METABOLITE	0.100298142
N03AX14	levetiracetam	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.001398188
D10AX03	azelaic acid	C0162835	hypopigmentation	1	[P14679]	DRUG	0.021299045
N07XX02	riluzole	C0039231	tachycardia	1	[Q14524]	DRUG	0.023338897
L01BC06	capecitabine	C0016059	fibrosis	2	[Q15077, P19971]	DRUG_AND_METABOLITE	0.070729524
N04BC05	pramipexole	C0018802	congestive heart failure	2	[Q9Y2I1, P07550]	DRUG	0.043470156
N04BC05	pramipexole	C0018801	heart failure	2	[Q9Y2I1, P07550]	DRUG	0.043470156
R06AD02	promethazine	C0011603	dermatitis	2	[P28223, P08908]	DRUG	0.190264287
N03AG06	tiagabine	C0033975	psychosis	1	[Q99259]	DRUG	0.122499116
N05AB06	trifluoperazine	C0014553	petit mal	4	[Q9UBS5, O43526, Q99250, P35498]	DRUG_AND_METABOLITE	0.013399503
N05AB06	trifluoperazine	C0014549	grand mal	3	[O43526, Q99250, P35498]	DRUG_AND_METABOLITE	0.019239124
C08CA05	nifedipine	C0015230	rash	1	[P28223]	DRUG	0.3164754
C01BA02	procainamide	C0024141	lupus	1	[P26358]	DRUG	0.203641648
C07AB03	atenolol	C0018790	cardiac arrest	1	[P07550]	DRUG	0.037934867
L04AX02	thalidomide	C0015230	rash	1	[P01375]	DRUG	0.448409981
M01AE02	naproxen	C0022658	nephropathy	2	[P02768, P23219]	DRUG	0.091635769
M03BX08	cyclobenzaprine	C0018681	headache	1	[P05362]	METABOLITE	0.111497832
B01AC07	dipyridamole	C0003864	arthritis	1	[P07900]	DRUG	0.12313969
L02BB01	flutamide	C0019158	hepatitis	1	[P23219]	METABOLITE	0.157523633
L04AX04	lenalidomide	C0020542	pulmonary hypertension	1	[P35354]	DRUG	0.078146652
L02BB03	bicalutamide	C0019360	herpes zoster	1	[P03372]	DRUG	0.010207101
L04AX04	lenalidomide	C0020538	hypertension	4	[P20815, Q08499, P11712, P01375]	DRUG	0.009652814
C01BB01	lidocaine	C0039231	tachycardia	1	[Q14524]	DRUG	0.038508848
L04AA13	leflunomide	C0011849	diabetes mellitus	2	[P11712, P10632]	DRUG	0.059662382
A10BB09	gliclazide	C0022408	arthrosis	1	[P15692]	DRUG	0.051696381
M01AB02	sulindac	C0002871	anemia	1	[P02768]	DRUG	0.088488982
M01AE09	flurbiprofen	C0041582	ulcer	1	[P10145]	DRUG	0.047592614
M01AB02	sulindac	C0002874	aplastic anemia	1	[P04798]	DRUG	0.11159148
L04AX04	lenalidomide	C0020517	hypersensitivity	1	[P01375]	DRUG	0.082281156
A07EA06	budesonide	C0013395	Dyspepsia	1	[P23219]	METABOLITE	0.040283843
N04BD01	selegiline	C0009806	constipation	3	[P46098, P41595, P31645]	METABOLITE	0.00011366
R03DA04	theophylline	C0035410	rhabdomyolysis	1	[P21817]	METABOLITE	0.038001816
J05AF05	lamivudine	C0043144	wheezing	1	[P33527]	DRUG	0.24849921
N05CF03	zaleplon	C0149931	migraine	1	[P08684]	DRUG	0.046871884
N03AE01	clonazepam	C0033975	psychosis	1	[P21397]	DRUG_AND_METABOLITE	0.111855571
M01AC06	meloxicam	C0006266	bronchospasm	3	[P09917, P35354, P23219]	DRUG_AND_METABOLITE	0.007256171
N04BC05	pramipexole	C0018799	heart disease	4	[P31645, P08588, P07550, P41595]	DRUG	0.034839743
N04BC05	pramipexole	C0018790	cardiac arrest	2	[P18089, P07550]	DRUG	0.01337726
C09CA01	losartan	C0019559	hip pain	1	[Q08499]	DRUG	0.019028106
J02AC01	fluconazole	C0151798	hepatic necrosis	2	[P09601, P08684]	DRUG	0.014253709
D05BB02	acitretin	C0019080	hemorrhage	1	[P21731]	METABOLITE	0.077866045
N06AA09	amitriptyline	C0036572	seizures	3	[O43526, Q99250, P35498]	DRUG_AND_METABOLITE	0.010302995
G02CB03	cabergoline	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.014025764
M01AH01	celecoxib	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG	3.59294E-07
C07AB03	atenolol	C0006266	bronchospasm	1	[P07550]	DRUG	0.190102925
C01AA05	digoxin	C0018799	heart disease	1	[P40763]	DRUG_AND_METABOLITE	0.258879834
C09AA02	enalapril	C0027051	myocardial infarction	2	[P12821, P00797]	METABOLITE	0.05875587
A02BB01	misoprostol	C0006266	bronchospasm	3	[Q13258, Q9Y5Y4, P43115]	DRUG_AND_METABOLITE	0.013399503
N02CC06	eletriptan	C0003873	rheumatoid arthritis	1	[P23219]	DRUG	0.278336671
A01AC01	triamcinolone	C0027051	myocardial infarction	1	[P04150]	DRUG	0.085527439
M01AE01	ibuprofen	C0004093	asthenia	3	[P31645, P28223, P35354]	DRUG	0.000921663
M01AE01	ibuprofen	C0004096	asthma	6	[P09917, P10145, P35354, P23219, O94956, P33527]	DRUG	0.05696568
L01XE03	erlotinib	C0027051	myocardial infarction	1	[Q02763]	DRUG_AND_METABOLITE	0.499995859
J01FA10	azithromycin	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.061653521
N06BA04	methylphenidate	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
N06AA04	clomipramine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.001257442
C09AA05	ramipril	C0033687	proteinuria	1	[P12821]	DRUG	0.016701405
N05CD01	flurazepam	C0018524	hallucinations	1	[P08183]	DRUG	0.096910793
N07XX02	riluzole	C0027813	neuritis	1	[O00555]	DRUG	0.054232974
A02BC01	omeprazole	C0032584	polyps	8	[P05177, P08183, Q9UNQ0, Q16678, P32247, Q07820, P04798, O15438]	DRUG_AND_METABOLITE	0.081682023
N05AD01	haloperidol	C0020538	hypertension	11	[P20815, P35348, P07550, P21728, P31645, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG	0.000739632
N01AH01	fentanyl	C0010709	cyst	3	[P08183, Q12809, P20815]	DRUG	0.270660425
C09CA02	eprosartan	C0011849	diabetes mellitus	2	[P11712, P30556]	DRUG	0.023202726
A02BC02	pantoprazole	C0021311	infection	1	[P08575]	METABOLITE	0.443039998
A07EA06	budesonide	C0018681	headache	1	[P35228]	METABOLITE	0.058976887
C10AA04	fluvastatin	C0002994	angioedema	1	[P27487]	DRUG_AND_METABOLITE	0.006114053
L04AX02	thalidomide	C0151950	deep thrombophlebitis	1	[P00488]	METABOLITE	0.273660949
S01AA14	penicillin G	C0006266	bronchospasm	3	[P12319, P16050, O94956]	DRUG	0.160248208
L02BA01	tamoxifen	C0030193	pain	1	[P11511]	DRUG	0.042381513
N05AX12	aripiprazole	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG_AND_METABOLITE	9.55426E-06
N03AX16	pregabalin	C0027651	tumor	1	[Q01650]	DRUG	0.496694827
L01BA01	methotrexate	C0149871	deep vein thrombosis	1	[P42898]	DRUG	0.119381023
S01ED02	betaxolol	C0001824	agranulocytosis	1	[P08183]	METABOLITE	0.048334546
N06DA02	donepezil	C0021311	infection	3	[P49682, P23219, P05067]	DRUG	0.049265362
L01AA01	cyclophosphamide	C0011849	diabetes mellitus	4	[P11712, O15245, P08684, P10632]	DRUG	0.003209136
L02BG03	anastrozole	C0027051	myocardial infarction	2	[P11712, P05177]	DRUG_AND_METABOLITE	0.052378179
C09AA13	moexipril	C0038454	cerebrovascular accident	1	[P12821]	DRUG_AND_METABOLITE	0.065144151
N02AA03	hydromorphone	C0015230	rash	1	[P31645]	METABOLITE	0.25753957
N06AX05	trazodone	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.009279632
J05AF03	zalcitabine	C0033975	psychosis	1	[P54098]	METABOLITE	0.122499116
J05AF04	stavudine	C0002871	anemia	1	[P02768]	METABOLITE	0.107484566
M03BX08	cyclobenzaprine	C0020565	breast enlargement	1	[P05362]	METABOLITE	0.251318077
M01AB05	diclofenac	C0042373	Vascular Disorders	1	[P10145]	DRUG_AND_METABOLITE	0.230280487
M03BX08	cyclobenzaprine	C0020538	hypertension	13	[P20815, P35348, P13945, P07550, P21728, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	0.000256201
A04AD12	aprepitant	C0011849	diabetes mellitus	2	[P11712, P08684]	DRUG_AND_METABOLITE	0.028343005
M03BX08	cyclobenzaprine	C0020517	hypersensitivity	7	[P05362, P41595, Q8NER1, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	2.23553E-05
J01DB04	cefazolin	C0009319	colitis	1	[P27169]	DRUG	0.119180074
J05AE01	saquinavir	C0023530	leukopenia	2	[Q92887, P08183]	DRUG	0.008236987
C01BD01	amiodarone	C0004238	atrial fibrillation	1	[Q14524]	DRUG	0.099143217
N06AA11	protriptyline	C0013604	edema	1	[P08588]	DRUG	0.06589552
N05AE04	ziprasidone	C0011206	delirium	2	[P32238, P21554]	DRUG	0.009457734
M01AE02	naproxen	C0022408	arthrosis	3	[Q9H3N8, P07858, P49768]	DRUG	0.038904919
C07AB02	metoprolol	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.053194386
R03AC02	salbutamol	C0013537	eclampsia	2	[P07550, P13945]	DRUG	0.005150097
L04AA06	mycophenolic acid	C0010709	cyst	2	[P22309, P37231]	DRUG_AND_METABOLITE	0.114588485
N06DX01	memantine	C0019158	hepatitis	1	[P11509]	DRUG	0.091184812
C08CA01	amlodipine	C0030305	pancreatitis	1	[P04798]	DRUG	0.141496851
N05CF01	zopiclone	C0149931	migraine	1	[P08684]	DRUG	0.077572058
N06AA04	clomipramine	C0009951	convulsions	11	[P35498, Q9UBS5, P08183, P36544, Q99250, P04156, Q9NY46, P30874, P08908, P31645, P29475]	METABOLITE	5.82409E-05
C01BD01	amiodarone	C0027947	neutropenia	1	[P08183]	DRUG	0.062641595
C09CA01	losartan	C0035078	renal failure	3	[P30556, P12821, P08183]	DRUG	0.002300762
N03AX09	lamotrigine	C0026650	movement disorders	1	[P35498]	DRUG	0.049831833
L02BB01	flutamide	C0015230	rash	1	[P50135]	METABOLITE	0.284913815
N05AX12	aripiprazole	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.031834971
J05AE01	saquinavir	C0027947	neutropenia	2	[Q92887, P08183]	DRUG	0.005338165
N05AH02	clozapine	C0023530	leukopenia	1	[P08183]	DRUG	0.170463016
A07EC04	balsalazide	C0032285	pneumonia	1	[P35354]	DRUG_AND_METABOLITE	0.074349356
A04AD12	aprepitant	C0018944	hematoma	1	[P11712]	DRUG_AND_METABOLITE	0.03201379
R06AE07	cetirizine	C0003864	arthritis	1	[Q9H3N8]	DRUG	0.044434339
C09AA06	quinapril	C0042109	urticaria	1	[P12821]	DRUG_AND_METABOLITE	0.015087595
N05AH02	clozapine	C0011206	delirium	1	[P21554]	DRUG	0.087023603
G04BE07	apomorphine	C0042029	urinary tract infection	1	[P03973]	DRUG	0.059946991
H02AB02	dexamethasone	C0021311	infection	5	[P35228, P35354, P23219, P09917, P04150]	DRUG_AND_METABOLITE	0.104118046
N05AH04	quetiapine	C0242422	Parkinson	10	[P21917, Q01959, P32238, P08183, P21554, P50406, P08908, P31645, P14416, P35462]	DRUG_AND_METABOLITE	1.45615E-05
M04AA01	allopurinol	C0026848	myopathy	1	[P23109]	METABOLITE	0.32312495
N06AB08	fluvoxamine	C0038454	cerebrovascular accident	1	[P28223]	DRUG_AND_METABOLITE	0.182244971
J05AF03	zalcitabine	C0019080	hemorrhage	1	[P11712]	DRUG	0.086839232
D10AA02	methylprednisolone	C0006266	bronchospasm	1	[P04150]	DRUG_AND_METABOLITE	0.13182434
L04AA06	mycophenolic acid	C0022346	jaundice	1	[P22309]	DRUG_AND_METABOLITE	0.009048263
L04AX02	thalidomide	C0151908	dry skin	2	[Q07343, P01375]	DRUG	0.18458557
G03AC06	medroxyprogesterone	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.042475697
N06AA21	maprotiline	C0001824	agranulocytosis	1	[P08183]	DRUG	0.05490586
N06DA03	rivastigmine	C0013595	eczema	1	[P31645]	DRUG	0.082841128
J05AE04	nelfinavir	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.057691049
N06AA17	amoxapine	C0020538	hypertension	10	[P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	METABOLITE	8.65131E-05
H02AB02	dexamethasone	C0021390	inflammatory bowel disease	5	[P09917, P03956, P08183, P08684, P20815]	DRUG_AND_METABOLITE	0.001143986
N06AB06	sertraline	C0023530	leukopenia	1	[P08183]	DRUG	0.093159412
C10AA07	rosuvastatin	C0020538	hypertension	3	[P20815, P27487, P11712]	DRUG	0.007455605
N05AD01	haloperidol	C0020615	hypoglycemia	2	[P07550, P30874]	DRUG	0.042804682
C04AD03	pentoxifylline	C0015230	rash	1	[P01375]	DRUG_AND_METABOLITE	0.127783868
L02BA01	tamoxifen	C0030305	pancreatitis	3	[P05181, P04798, P35354]	DRUG	0.017783546
J05AE01	saquinavir	C0023467	AML	3	[Q9UNQ0, P08183, P33527]	DRUG	0.035047926
M01AE03	ketoprofen	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.001184871
C01BB02	mexiletine	C0018802	congestive heart failure	3	[Q9Y2I1, Q14524, P07550]	METABOLITE	0.024401265
N06AB08	fluvoxamine	C0010709	cyst	6	[P05177, P08183, P20815, P05181, P04798, P23975]	DRUG_AND_METABOLITE	0.10492878
L02BG04	letrozole	C0022658	nephropathy	1	[P00918]	DRUG	0.041143563
C09CA01	losartan	C0015672	fatigue	1	[P12821]	DRUG	0.039806384
N05CF01	zopiclone	C0017152	gastritis	1	[P23219]	DRUG	0.077572058
A02BC04	rabeprazole	C0242184	hypoxia	1	[P35354]	DRUG	0.424559988
C08CA05	nifedipine	C0003811	arrhythmia	1	[P22460]	DRUG	0.069639772
N04BC05	pramipexole	C0001418	adenocarcinoma	3	[P07550, Q9H3N8, Q9Y5N1]	DRUG	0.494495624
J01MA02	ciprofloxacin	C0027813	neuritis	1	[P08183]	DRUG	0.052057421
R03AC02	salbutamol	C0013604	edema	1	[P08588]	DRUG	0.010569187
L01XE03	erlotinib	C0027651	tumor	124	[P31749, P42336, Q9UNQ0, P07333, P08684, P00533, P04626, P21802, P11309, P08183, P46734, Q9UK32, P35968, Q14289, P37173, P36897, P10721, Q14164, Q15746, Q9Y243, O60674, Q15303, P22455, P68400, P28482, P22607, P27361, P45985, P41240, Q16539, P29317, Q08345, P43405, P08069, P49137, Q13153, P08581, P51813, P07949, O14965, P12931, P42685, P50750, P24941, P16234, Q13177, Q96GD4, Q13873, P07948, Q05397, Q15831, P07947, Q07912, Q13882, P17948, P60953, P31751, P00519, P68366, P45984, Q15418, Q15349, Q9UKI8, P17612, P06239, Q02156, Q05655, P53667, P11362, P45983, Q13164, Q04759, P48730, P49674, P49841, P51812, Q9UIK4, Q15375, Q02763, P53350, P51955, Q9P289, P09619, O75582, P15056, Q92918, P43403, P53355, P50613, O43293, Q16832, P04629, P35916, O14757, P54762, P54760, P07332, Q9UM73, P52333, P24723, P06213, P29597, P29323, P19525, P36894, Q00526, P06241, O95835, P21709, Q02750, P36507, P49840, Q9NRM7, P23458, Q16620, P22694, Q9NQU5, P16591, Q15139, P27037, P04049, Q00535, Q9P1W9, Q13546]	DRUG_AND_METABOLITE	0.029637746
R03AC12	salmeterol	C0042109	urticaria	1	[P07550]	DRUG	0.025394378
N03AX16	pregabalin	C0027813	neuritis	1	[O00555]	DRUG	0.038275109
D10AA02	methylprednisolone	C0027051	myocardial infarction	2	[P10275, P04150]	DRUG_AND_METABOLITE	0.034440795
R03DA04	theophylline	C0020456	hyperglycemia	1	[P01375]	METABOLITE	0.209627809
C09AA03	lisinopril	C0009443	common cold	1	[Q9BYF1]	DRUG	0.146814213
N04BC04	ropinirole	C0020615	hypoglycemia	1	[P07550]	DRUG	0.07985866
N06AB04	citalopram	C0027932	neurosis	4	[P23975, P31645, P28223, P14416]	DRUG	5.17627E-07
B01AC05	ticlopidine	C0015230	rash	1	[P08908]	METABOLITE	0.209546795
L01XE02	gefitinib	C0206061	interstitial pneumonitis	2	[P43405, P20783]	DRUG_AND_METABOLITE	0.258243924
L01XE02	gefitinib	C0206062	interstitial lung disease	1	[P20783]	DRUG_AND_METABOLITE	0.135133707
M01AB08	etodolac	C0019158	hepatitis	3	[P23219, P35354, P02768]	DRUG	0.00054791
L01XE01	imatinib	C0042373	Vascular Disorders	3	[P37023, P36897, P37173]	DRUG	0.280790869
L04AX02	thalidomide	C1261473	sarcoma	1	[P35354]	DRUG_AND_METABOLITE	0.428572625
J01MA02	ciprofloxacin	C1456784	paranoia	1	[P05177]	DRUG	0.016169699
N05CD08	midazolam	C0009951	convulsions	4	[P18507, P08183, P28472, P47870]	DRUG_AND_METABOLITE	0.003300583
L01XB01	procarbazine	C0020538	hypertension	1	[P47989]	DRUG	0.059662382
N05AC02	thioridazine	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG_AND_METABOLITE	1.12325E-05
R06AX17	ketotifen	C0151827	eye pain	1	[Q08499]	DRUG	0.049485821
N06AA04	clomipramine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.093425362
J01MA02	ciprofloxacin	C0018799	heart disease	1	[Q12809]	DRUG	0.190312528
J01MA02	ciprofloxacin	C0018790	cardiac arrest	1	[Q12809]	DRUG	0.043339606
M01AB05	diclofenac	C0009806	constipation	2	[P46098, P41595]	DRUG	0.005809415
N03AX09	lamotrigine	C0009319	colitis	2	[P08183, Q14524]	DRUG	0.035866818
M01AE02	naproxen	C0022346	jaundice	1	[P22309]	DRUG	0.046003348
N06AA04	clomipramine	C0005747	blepharospasm	2	[P21918, P14416]	DRUG_AND_METABOLITE	0.054232974
N05CF01	zopiclone	C1458155	breast neoplasm	4	[P08684, P30536, O00591, P05181]	DRUG	0.429296964
B01AC07	dipyridamole	C0019080	hemorrhage	1	[P00813]	DRUG	0.06495498
C07AG02	carvedilol	C0013395	Dyspepsia	1	[P23219]	DRUG	0.030408848
M01AB08	etodolac	C0027051	myocardial infarction	4	[P35354, P02768, P11712, P23219]	DRUG_AND_METABOLITE	0.003958486
A02BC01	omeprazole	C0020453	hyperesthesia	1	[Q8NER1]	DRUG	0.036486436
C01BD01	amiodarone	C0016059	fibrosis	1	[P04798]	DRUG	0.207795844
L04AX02	thalidomide	C0151827	eye pain	1	[Q08499]	DRUG	0.117247144
L04AX02	thalidomide	C0151825	bone pain	1	[Q08499]	DRUG	0.04898487
P01AX06	atovaquone	C0030305	pancreatitis	3	[P05181, P09211, P42898]	METABOLITE	0.126978483
N04BC02	pergolide	C0029456	osteoporosis	1	[P08684]	DRUG	0.151656571
L01XE01	imatinib	C0034150	purpura	1	[P08581]	DRUG	0.276586801
L02BG06	exemestane	C0010054	coronary artery disease	2	[P08684, P10275]	METABOLITE	0.016169699
N04BC02	pergolide	C0029463	bone sarcomas	1	[P08684]	DRUG	0.227288826
J05AE01	saquinavir	C0027651	tumor	11	[Q9UNQ0, P08684, P08183, Q92887, P33527, Q99720, P46721, P05108, P20815, P10632, P33261]	DRUG	0.094765172
M01AC01	piroxicam	C0009951	convulsions	1	[P35354]	DRUG_AND_METABOLITE	0.089912296
L04AX02	thalidomide	C0015672	fatigue	1	[P35354]	DRUG_AND_METABOLITE	0.104607438
M01AH01	celecoxib	C0014544	epilepsy	1	[P33527]	DRUG	0.225248202
D06BB10	imiquimod	C0010709	cyst	1	[P05177]	DRUG	0.266243108
L01AX03	temozolomide	C0041912	upper respiratory tract infection	1	[P00519]	DRUG	0.248968302
R03AC02	salbutamol	C0013595	eczema	1	[P07550]	DRUG	0.057620471
N02CC02	naratriptan	C0011603	dermatitis	1	[P08908]	DRUG	0.089912296
M01AB08	etodolac	C0019080	hemorrhage	1	[P11712]	DRUG	0.05003026
N05AX12	aripiprazole	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	6.82807E-05
N06AA04	clomipramine	C0013595	eczema	5	[P07550, P28223, P08908, P31645, P09211]	DRUG	0.048802215
M01AH03	valdecoxib	C0007117	basal cell carcinoma	1	[P35354]	DRUG_AND_METABOLITE	0.192426082
N03AX16	pregabalin	C0042376	vascular headache	1	[O00555]	DRUG	0.022963468
S01GX09	olopatadine	C0020517	hypersensitivity	1	[P35367]	DRUG_AND_METABOLITE	0.045777432
N03AG01	valproic acid	C0004134	ataxia	1	[P80404]	DRUG	0.128765153
J02AC03	voriconazole	C0019080	hemorrhage	2	[P24557, P11712]	DRUG	0.003004332
R06AA04	clemastine	C0043144	wheezing	1	[P11229]	DRUG	0.190102925
N05BA02	chlordiazepoxide	C0001824	agranulocytosis	4	[Q92887, Q9NPD5, P22309, P08183]	DRUG_AND_METABOLITE	0.000591467
N05AB03	perphenazine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG	0
N05AH02	clozapine	C0027947	neutropenia	1	[P08183]	DRUG	0.140012694
M01AB05	diclofenac	C0009951	convulsions	4	[P08183, P33527, P08908, P35354]	DRUG_AND_METABOLITE	0.025451129
N05AX12	aripiprazole	C0003864	arthritis	1	[Q9H3N8]	DRUG_AND_METABOLITE	0.269233542
N05AX12	aripiprazole	C0003873	rheumatoid arthritis	3	[P21554, Q9H3N8, P07550]	DRUG_AND_METABOLITE	0.336645164
A01AC01	triamcinolone	C0015672	fatigue	2	[P08185, P04150]	DRUG	6.65688E-05
N01BB09	ropivacaine	C0004238	atrial fibrillation	2	[P22460, Q14524]	METABOLITE	0.021961143
N02AX02	tramadol	C0013595	eczema	1	[P31645]	DRUG_AND_METABOLITE	0.127783868
D05BB02	acitretin	C0003123	anorexia	1	[P21397]	METABOLITE	0.084655509
J05AE04	nelfinavir	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.048334546
C10AA06	cerivastatin	C0011991	diarrhea	1	[Q92887]	DRUG_AND_METABOLITE	0.033737522
C07AA15	carteolol	C0006266	bronchospasm	1	[P07550]	DRUG	0.156888602
N05AX12	aripiprazole	C0009951	convulsions	4	[Q9UBS5, P36544, P08908, P31645]	DRUG_AND_METABOLITE	0.027175081
C09CA02	eprosartan	C0011991	diarrhea	1	[Q92887]	DRUG	0.019687894
G03DA04	progesterone	C0001969	drunk	7	[P47869, P28223, P21728, P08908, P05181, P14416, P21397]	METABOLITE	8.92708E-07
M01AH03	valdecoxib	C0007097	carcinoma	8	[P35354, P33527, Q16790, P23219, P08842, Q9Y5N1, P08684, O43570]	DRUG_AND_METABOLITE	0.49704527
A10BB09	gliclazide	C0006444	bursitis	1	[P15692]	DRUG	0.014253709
A04AA02	granisetron	C1527304	allergic reaction	1	[P41595]	DRUG	0.073492304
C02CA01	prazosin	C0011991	diarrhea	1	[P46098]	DRUG	0.070199651
C03BA11	indapamide	C0030305	pancreatitis	1	[P00918]	DRUG_AND_METABOLITE	0.12507432
C08CA05	nifedipine	C0015672	fatigue	1	[P28223]	DRUG	0.061564341
N05AC02	thioridazine	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.005396749
J05AF03	zalcitabine	C0021311	infection	2	[P61073, P81605]	METABOLITE	0.344347567
N06AX21	duloxetine	C0039070	syncope	1	[P29274]	DRUG	0.087386772
N07XX02	riluzole	C0600139	prostate cancer	3	[Q9UNQ0, P04798, P05177]	DRUG	0.355607328
R03DC03	montelukast	C0018799	heart disease	2	[P23219, P11712]	DRUG_AND_METABOLITE	0.030158216
N01BB01	bupivacaine	C0009951	convulsions	4	[P35498, P08183, Q99250, Q9NY46]	DRUG_AND_METABOLITE	0.007907224
N05BC01	meprobamate	C0042109	urticaria	1	[P07550]	METABOLITE	0.180289965
C09CA01	losartan	C0003811	arrhythmia	1	[P12821]	DRUG	0.044396476
L01XE01	imatinib	C0034069	pulmonary fibrosis	3	[P04626, P20783, Q05655]	DRUG	0.238420693
N02AE01	buprenorphine	C0003123	anorexia	3	[P41143, P31645, P23975]	DRUG	0.000776114
R03AC13	formoterol	C0024115	lung disorder	1	[P07550]	DRUG	0.113598475
N06AA01	desipramine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG	1.38058E-06
N06AA09	amitriptyline	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.174370945
C09AA08	cilazapril	C0024141	lupus	1	[P12821]	DRUG	0.079339377
G02CB03	cabergoline	C0015672	fatigue	1	[P28223]	DRUG	0.037086334
N06AX06	nefazodone	C0149931	migraine	4	[P28223, P31645, P08684, P28335]	DRUG_AND_METABOLITE	0.000354122
J01DD04	ceftriaxone	C0002871	anemia	1	[P02768]	DRUG	0.040204533
N06DA02	donepezil	C0015230	rash	1	[P28223]	DRUG	0.121293293
C09AA10	trandolapril	C0038454	cerebrovascular accident	1	[P12821]	DRUG_AND_METABOLITE	0.05696568
J02AC03	voriconazole	C0019158	hepatitis	1	[P23219]	DRUG	0.063596471
J05AF01	zidovudine	C0003123	anorexia	1	[P28223]	METABOLITE	0.076067973
N06DA03	rivastigmine	C0001418	adenocarcinoma	2	[P06276, P08684]	DRUG	0.178569817
L01XX05	hydroxyurea	C0031117	peripheral neuropathy	1	[P14780]	METABOLITE	0.019687894
N06AA04	clomipramine	C0013384	dyskinesia	6	[Q14643, P35498, Q12791, P14416, P21917, P35462]	DRUG_AND_METABOLITE	0.000286882
M01AH02	rofecoxib	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.03537307
L01XE01	imatinib	C0026986	myelodysplastic syndrome	17	[P06748, O60674, P28482, Q06187, P08183, P08069, P36888, P17948, P10721, P31749, P27361, P16234, Q13237, P52333, P09619, P11274, P11362]	DRUG	2.99685E-05
P01AX06	atovaquone	C0042109	urticaria	1	[P07550]	METABOLITE	0.173919458
M01AH02	rofecoxib	C0038358	gastric ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.015848121
M01AH02	rofecoxib	C0010692	cystitis	1	[P03973]	DRUG	0.098925104
N05AA01	chlorpromazine	C0014553	petit mal	4	[Q9UBS5, O43526, Q99250, P35498]	DRUG_AND_METABOLITE	0.013399503
M04AB01	probenecid	C0002871	anemia	1	[P02768]	DRUG	0.107484566
N05AA01	chlorpromazine	C0014549	grand mal	3	[O43526, Q99250, P35498]	DRUG_AND_METABOLITE	0.019239124
N03AB04	mephenytoin	C0024299	lymphoma	1	[P08183]	DRUG	0.393925702
L01AX03	temozolomide	C0002874	aplastic anemia	1	[P04798]	METABOLITE	0.064790585
N05CD02	nitrazepam	C0018834	heartburn	1	[P23219]	DRUG	0.05875587
C07AG02	carvedilol	C0013604	edema	2	[P15692, P08588]	DRUG_AND_METABOLITE	0.001365729
L01BA01	methotrexate	C0021311	infection	2	[P42898, P47989]	DRUG	0.368739093
C09CA01	losartan	C0007642	cellulitis	1	[Q07343]	DRUG	0.138903961
N03AF01	carbamazepine	C0156312	testicular atrophy	1	[P35354]	METABOLITE	0.120607843
N02AA01	morphine	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG_AND_METABOLITE	0.000590875
N06AB08	fluvoxamine	C0020604	hypochondriasis	1	[P31645]	DRUG_AND_METABOLITE	0.008782102
M01AG01	mefenamic acid	C0013395	Dyspepsia	1	[P23219]	DRUG	0.017783546
M01AH02	rofecoxib	C0002103	allergic rhinitis	1	[P11712]	DRUG_AND_METABOLITE	0.20790867
N04BD01	selegiline	C0009319	colitis	4	[P08183, P31645, P46098, P41595]	METABOLITE	0.015801023
L01XE01	imatinib	C0014457	eosinophilia	2	[P16234, P00519]	DRUG_AND_METABOLITE	0.076424254
R06AB04	chlorpheniramine	C0003123	anorexia	4	[P28223, P28335, P31645, P23975]	DRUG	0.000103516
S01ED02	betaxolol	C0011570	mental depression	4	[P33261, P28335, P28222, P08908]	METABOLITE	2.08794E-05
C09AA08	cilazapril	C0004238	atrial fibrillation	1	[P12821]	DRUG	0.030969403
L01AB01	busulfan	C0027651	tumor	5	[P08684, P08263, P00325, P00326, P40394]	METABOLITE	0.164896017
C10AA04	fluvastatin	C0021311	infection	3	[P27487, P37231, Q07869]	METABOLITE	0.071408613
C01BB02	mexiletine	C0020538	hypertension	10	[P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	METABOLITE	0.000815317
N05BA06	lorazepam	C0033975	psychosis	1	[P21397]	DRUG_AND_METABOLITE	0.100870409
N04BC05	pramipexole	C0026640	oral neoplasm	1	[P23975]	DRUG	0.499995859
A03FA03	domperidone	C0015230	rash	1	[P28223]	DRUG	0.188454274
C01BB02	mexiletine	C0020517	hypersensitivity	4	[P41595, Q01959, P35367, P25021]	METABOLITE	0.002697338
C01BC03	propafenone	C0037052	sick sinus syndrome	1	[Q14524]	DRUG	0.005809415
N06BC01	caffeine	C0243026	sepsis	3	[P47989, O00408, P11217]	DRUG	0.030399173
N03AX11	topiramate	C0017168	gastroesophageal reflux	1	[P33261]	DRUG	0.045033357
C10AA02	lovastatin	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.19053119
L04AX02	thalidomide	C0003864	arthritis	2	[P19838, P01375]	DRUG	0.204267744
J05AE03	ritonavir	C0004096	asthma	1	[P33527]	DRUG	0.265101728
N06AA10	nortriptyline	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.306764942
M01AH02	rofecoxib	C0010709	cyst	6	[P05177, P16050, P35354, P33527, P23975, P09917]	DRUG_AND_METABOLITE	0.434291704
N05AD01	haloperidol	C0001824	agranulocytosis	2	[O60656, P08183]	DRUG	0.032040111
N04BD01	selegiline	C0013595	eczema	3	[P28223, P08908, P31645]	METABOLITE	0.037700893
C09AA08	cilazapril	C0004093	asthenia	1	[P12821]	DRUG	0.012425662
G03BA03	testosterone	C0035078	renal failure	1	[P08183]	METABOLITE	0.247417559
G02CB01	bromocriptine	C0038220	status epilepticus	1	[Q9UBS5]	DRUG	0.091683405
D07AC08	fluocinonide	C0020456	hyperglycemia	1	[Q99835]	DRUG	0.025896476
N04BC04	ropinirole	C0086769	panic attacks	3	[P08908, P28223, P46098]	DRUG	0.000471016
N03AX11	topiramate	C0005586	bipolar disorder	1	[P39086]	DRUG	0.124059223
C08CA05	nifedipine	C0151744	myocardial ischemia	1	[Q12809]	DRUG	0.146225677
A07EA06	budesonide	C0235761	nasal septum perforation	4	[P35354, P04083, P07148, P35228]	METABOLITE	0.006002348
C09AA02	enalapril	C0023530	leukopenia	1	[P08183]	DRUG	0.044087091
N06AB08	fluvoxamine	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.103777387
N03AX09	lamotrigine	C0030920	peptic ulcer	1	[P33261]	DRUG	0.057987175
N03AA03	primidone	C0004134	ataxia	1	[P35498]	METABOLITE	0.12745769
N06AB03	fluoxetine	C0242184	hypoxia	4	[P08172, P11229, P10275, Q12809]	DRUG	0.08498899
R01AD01	beclomethasone	C0002792	anaphylaxis	1	[P35228]	DRUG_AND_METABOLITE	0.084103037
N03AB04	mephenytoin	C0024141	lupus	1	[Q92887]	DRUG	0.364854773
N03AX11	topiramate	C0001122	acidosis	1	[Q16790]	DRUG	0.045033357
C10AB04	gemfibrozil	C0085096	peripheral vascular disorder	1	[P37231]	DRUG	0.064996834
H02AB07	prednisone	C0027651	tumor	19	[Q9UNQ0, P11511, P08684, P03372, P08183, P06401, Q92731, P04278, P08235, P46721, P10275, P04083, P04150, P20815, P10632, P11509, P15104, Q09470, P33261]	METABOLITE	0.000810085
N01BB09	ropivacaine	C0162297	respiratory arrest	1	[Q9UQD0]	METABOLITE	0.061350686
M01AH03	valdecoxib	C0023798	lipoma	5	[O43570, P35354, P33527, Q16790, P08842]	DRUG_AND_METABOLITE	0.481655992
P01AX06	atovaquone	C0011991	diarrhea	1	[P46098]	METABOLITE	0.146688111
N02AX02	tramadol	C0018799	heart disease	2	[P31645, P20813]	DRUG	0.050716315
N04BC04	ropinirole	C0020550	hyperthyroidism	1	[P07550]	DRUG	0.096593322
G04BE07	apomorphine	C0018802	congestive heart failure	2	[P07550, O43306]	METABOLITE	0.045657764
N04BC04	ropinirole	C0020538	hypertension	7	[P35348, P07550, P21728, P28223, P08913, P18089, P08588]	DRUG	0.000274851
A04AA01	ondansetron	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.016860895
C09CA01	losartan	C0042109	urticaria	1	[P12821]	DRUG	0.057088716
N06AB08	fluvoxamine	C0020517	hypersensitivity	2	[Q01959, P35367]	DRUG_AND_METABOLITE	0.015405718
A03FA02	cisapride	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.040754414
L04AX04	lenalidomide	C0026821	muscle cramps	1	[Q08499]	DRUG	0.019239124
N06AB08	fluvoxamine	C0020538	hypertension	9	[P20815, P35348, P21728, P31645, P28223, P11712, P23975, P08913, P08588]	DRUG_AND_METABOLITE	1.38058E-06
M01AE02	naproxen	C0017152	gastritis	2	[P23219, P35354]	DRUG	0.040601904
N02CC06	eletriptan	C0020538	hypertension	1	[P11712]	DRUG	0.212234884
L01AX03	temozolomide	C0023470	myelogenous leukemia	1	[P00519]	DRUG	0.089636267
G03XA01	danazol	C0027651	tumor	13	[P11511, P08684, P03372, P06401, P04278, P13500, P05093, P10275, P30968, P20815, P18405, P31213, P35348]	METABOLITE	0.041492744
M01AH03	valdecoxib	C0015672	fatigue	3	[P31645, P28223, P35354]	DRUG_AND_METABOLITE	0.000366068
S01ED02	betaxolol	C0011603	dermatitis	2	[P07550, P08908]	METABOLITE	0.060216553
N04BC04	ropinirole	C0020517	hypersensitivity	2	[P41595, P35367]	DRUG	0.01936412
M03BX02	tizanidine	C0027051	myocardial infarction	2	[P05177, P18089]	DRUG	0.028174898
N06AA10	nortriptyline	C0011991	diarrhea	1	[P46098]	DRUG	0.094719012
N02AA03	hydromorphone	C0024299	lymphoma	1	[P08183]	DRUG_AND_METABOLITE	0.357067766
C07AB02	metoprolol	C0043144	wheezing	1	[P07550]	DRUG_AND_METABOLITE	0.220108265
G04BE08	tadalafil	C0151827	eye pain	1	[Q08499]	DRUG	0.044396476
R06AD02	promethazine	C0009951	convulsions	6	[P35498, P08183, Q99250, P04156, Q9NY46, P08908]	DRUG	0.000556696
J05AF05	lamivudine	C0009951	convulsions	1	[P33527]	DRUG	0.152175558
L02BA02	toremifene	C0027051	myocardial infarction	12	[P07203, P35354, P09488, P03372, P30711, P04798, P10275, Q92731, P11712, P33261, P23219, P05177]	DRUG_AND_METABOLITE	0.000374019
N03AG04	vigabatrin	C0004134	ataxia	1	[P80404]	DRUG	0.017783546
N05AC02	thioridazine	C0013604	edema	1	[P08588]	DRUG	0.063186267
G03DA04	progesterone	C0018799	heart disease	10	[P08588, P04278, P03372, P12104, Q92731, P11712, P19793, P20813, P04150, P33527]	DRUG_AND_METABOLITE	0.001513452
N07XX02	riluzole	C0036572	seizures	1	[Q99250]	DRUG	0.045033357
N04BD01	selegiline	C0013604	edema	1	[P08588]	METABOLITE	0.047831182
N04BC04	ropinirole	C1527304	allergic reaction	2	[P41595, P35367]	DRUG	0.013203379
C10AA06	cerivastatin	C0023890	cirrhosis	1	[P08684]	DRUG_AND_METABOLITE	0.12507432
L01XE01	imatinib	C0042769	viral infection	1	[P00533]	DRUG_AND_METABOLITE	0.372290424
G03AC06	medroxyprogesterone	C0021311	infection	2	[P03372, P04150]	DRUG_AND_METABOLITE	0.106277208
N02AA01	morphine	C0018790	cardiac arrest	1	[Q12809]	DRUG_AND_METABOLITE	0.07705633
N06AB03	fluoxetine	C0024902	breast pain	1	[Q08499]	METABOLITE	0.029823411
G03XA01	danazol	C0030794	pelvic pain	1	[P11511]	DRUG_AND_METABOLITE	0.027034852
C09AA05	ramipril	C0033860	psoriasis	1	[P12821]	DRUG	0.046661539
C10AA01	simvastatin	C0021311	infection	1	[P05107]	DRUG_AND_METABOLITE	0.338647638
A08AB01	orlistat	C0020517	hypersensitivity	1	[Q13093]	DRUG	0.05886078
N05AH03	olanzapine	C0037763	spasm	4	[P18507, P14867, P21918, P28472]	DRUG_AND_METABOLITE	2.99685E-05
R03AC12	salmeterol	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.014088111
C01BD01	amiodarone	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.044396476
C01AA05	digoxin	C0022116	ischemia	1	[P40763]	DRUG_AND_METABOLITE	0.112841395
P01BA01	chloroquine	C0878544	cardiomyopathy	2	[Q12809, P01375]	DRUG	0.024148754
N03AX09	lamotrigine	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	3.52831E-05
M01AB05	diclofenac	C0022346	jaundice	1	[P22309]	DRUG	0.044620172
N02CC01	sumatriptan	C0020517	hypersensitivity	1	[P41595]	DRUG	0.150166937
M01AB15	ketorolac	C0011991	diarrhea	1	[P10145]	DRUG	0.039009407
N06AA01	desipramine	C0011991	diarrhea	1	[P46098]	DRUG	0.097806013
N02CC01	sumatriptan	C0020538	hypertension	13	[P20815, P35348, P13945, P03372, P07550, P21728, Q02928, P28223, P11712, P08913, P18089, P08588, Q92731]	METABOLITE	3.59294E-07
G03CA03	estradiol	C0011991	diarrhea	1	[Q92887]	DRUG	0.105539171
C09AA03	lisinopril	C0024121	lung neoplasms	2	[P08183, P12821]	DRUG	0.039009407
G03BA02	methyltestosterone	C0042755	Masculinization	1	[P37058]	DRUG_AND_METABOLITE	0.021169216
N05AH02	clozapine	C0242422	Parkinson	10	[P21917, P05181, Q01959, P08183, P21554, P50406, P08908, P31645, P14416, P35462]	DRUG_AND_METABOLITE	9.70269E-05
N03AB04	mephenytoin	C0001824	agranulocytosis	2	[Q92887, P08183]	DRUG	0.015024931
N06AB04	citalopram	C1458155	breast neoplasm	8	[P08684, P08183, P05181, P05177, P20813, Q01959, Q12809, P23975]	DRUG_AND_METABOLITE	0.21961716
R03DA04	theophylline	C0003811	arrhythmia	1	[P21817]	METABOLITE	0.090729349
N01AH01	fentanyl	C1458155	breast neoplasm	5	[P08684, P08183, Q99720, Q12809, P20815]	DRUG	0.233319018
N05BE01	buspirone	C0018524	hallucinations	5	[P08183, P36544, P35498, Q99250, Q9NY46]	DRUG	0.000687259
C10AA05	atorvastatin	C0013295	duodenal ulcer	1	[P33261]	DRUG_AND_METABOLITE	0.047005538
N03AF02	oxcarbazepine	C0699744	ear infection	1	[Q16548]	DRUG	0.250793192
N03AX16	pregabalin	C0023055	laryngeal neoplasia	1	[Q01650]	DRUG	0.402364023
C08DB01	diltiazem	C0011991	diarrhea	1	[P46098]	DRUG	0.053194386
M01AE09	flurbiprofen	C0004096	asthma	4	[P10145, P08246, P35354, P23219]	DRUG_AND_METABOLITE	0.022331635
L04AA06	mycophenolic acid	C0008311	cholangitis	2	[P37231, P22309]	DRUG_AND_METABOLITE	0.000216216
M01AE09	flurbiprofen	C0004093	asthenia	1	[P35354]	DRUG_AND_METABOLITE	0.042475697
N06BA04	methylphenidate	C0018790	cardiac arrest	1	[P18089]	DRUG_AND_METABOLITE	0.080965538
G03AC06	medroxyprogesterone	C0014544	epilepsy	1	[P08183]	DRUG_AND_METABOLITE	0.068277531
N06BA04	methylphenidate	C0018799	heart disease	3	[P31645, Q13639, P41595]	DRUG_AND_METABOLITE	0.072104339
G02CB01	bromocriptine	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG	0.148905615
A08AA10	sibutramine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.001592396
M01AH03	valdecoxib	C0023530	leukopenia	1	[O60656]	DRUG_AND_METABOLITE	0.1248945
G03AC06	medroxyprogesterone	C0007784	cerebral hemorrhage	1	[P03372]	DRUG_AND_METABOLITE	0.101078094
G03AC06	medroxyprogesterone	C0007785	cerebral infarction	1	[P04150]	DRUG_AND_METABOLITE	0.045033357
N06AA12	doxepin	C0004096	asthma	7	[P07550, P05362, Q07817, P23219, P43115, P11229, P20309]	DRUG_AND_METABOLITE	0.091721007
M01AH02	rofecoxib	C0038454	cerebrovascular accident	3	[Q15722, P28223, P35354]	DRUG_AND_METABOLITE	0.04914709
N03AF01	carbamazepine	C0019158	hepatitis	2	[P23219, P35354]	METABOLITE	0.027162705
C01BD01	amiodarone	C0004134	ataxia	1	[Q9NY47]	DRUG	0.087579011
A02BC04	rabeprazole	C0015230	rash	1	[P47712]	METABOLITE	0.306667139
R01AD01	beclomethasone	C0027424	nasal congestion	1	[P35228]	DRUG_AND_METABOLITE	0.096593322
M01AE12	oxaprozin	C0009951	convulsions	1	[P35354]	DRUG	0.074982655
N06AX16	venlafaxine	C0020473	hyperlipidemia	1	[P07550]	DRUG	0.263056428
N06DA03	rivastigmine	C0018799	heart disease	1	[P31645]	DRUG	0.114032233
N06AX16	venlafaxine	C0020569	salivary gland enlargement	2	[Q14643, P20309]	DRUG_AND_METABOLITE	0.083263711
L01BC06	capecitabine	C0008031	chest pain	1	[P02768]	METABOLITE	0.019687894
N05AA01	chlorpromazine	C0018790	cardiac arrest	4	[Q12809, Q13936, P18089, P07550]	DRUG_AND_METABOLITE	0.002840837
N05BB01	hydroxyzine	C0018524	hallucinations	3	[P35498, Q99250, Q9NY46]	DRUG	0.000706253
M01AB05	diclofenac	C0022408	arthrosis	1	[P25024]	DRUG	0.268213578
N05AX12	aripiprazole	C0039520	tenosynovitis	1	[P35408]	DRUG_AND_METABOLITE	0.051004164
N06AX16	venlafaxine	C0020550	hyperthyroidism	2	[P07550, P08183]	DRUG	0.061166635
C09CA07	telmisartan	C0004096	asthma	1	[P37231]	DRUG	0.20086833
M01AE09	flurbiprofen	C0008325	cholecystitis	1	[P22309]	DRUG	0.056830903
N06AX16	venlafaxine	C0020538	hypertension	12	[P35348, P07550, P21728, P31645, P28223, P11712, P23975, P08913, P18089, P08588, Q12791, P29475]	DRUG	0.000221093
N06AB04	citalopram	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.002473457
N06AB04	citalopram	C0004096	asthma	1	[P11229]	DRUG	0.321076283
G03AC06	medroxyprogesterone	C0022665	renal tumor	5	[P08183, P06401, P03372, P08235, P10275]	METABOLITE	0.019381901
N04BC05	pramipexole	C0022104	irritable bowel syndrome	3	[P46098, P41595, P31645]	DRUG	0.001215327
C09CA01	losartan	C0042373	Vascular Disorders	1	[P12821]	DRUG	0.127160406
H03BB02	methimazole	C0040034	thrombocytopenia	1	[P07202]	DRUG	0.046530938
V03AH01	diazoxide	C0030552	weakness	1	[P55017]	DRUG	0.019028106
V03AF03	leucovorin	C0027947	neutropenia	1	[Q92887]	DRUG_AND_METABOLITE	0.037092814
A04AD12	aprepitant	C0018799	heart disease	1	[P11712]	DRUG_AND_METABOLITE	0.114032233
N02BA11	diflunisal	C0006266	bronchospasm	2	[P35354, P23219]	DRUG	0.070920127
N06AX21	duloxetine	C0027051	myocardial infarction	11	[P35354, P02768, P21554, P06276, P07550, P31645, P23219, P05177, P08588, P18089, Q12791]	DRUG	0.009694299
N06BA04	methylphenidate	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.036444908
C09AA03	lisinopril	C0024031	low back pain	1	[P12821]	DRUG	0.002297402
M01CB03	auranofin	C0015230	rash	1	[P07711]	DRUG	0.039368484
C01BA01	quinidine	C0001824	agranulocytosis	2	[Q92887, P08183]	DRUG	0.017207121
M03BX08	cyclobenzaprine	C0013395	Dyspepsia	1	[P23219]	METABOLITE	0.075916041
N02AA05	oxycodone	C0031212	personality disorder	1	[P31645]	DRUG	0.012425662
N06AB05	paroxetine	C0028077	night blindness	1	[O60840]	DRUG	0.036308188
M01AB05	diclofenac	C0030305	pancreatitis	4	[P05181, P04798, P00918, P35354]	DRUG_AND_METABOLITE	0.010732167
J05AF01	zidovudine	C0026848	myopathy	1	[O00142]	METABOLITE	0.128451012
N06AA11	protriptyline	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.086327305
C07AG02	carvedilol	C0032285	pneumonia	1	[P15692]	DRUG	0.108620866
M01AE02	naproxen	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG	7.23468E-05
C08DA01	verapamil	C0038454	cerebrovascular accident	1	[P28223]	DRUG	0.316364721
G03XA01	danazol	C0015672	fatigue	1	[P28223]	METABOLITE	0.037086334
N03AX09	lamotrigine	C0242422	Parkinson	2	[P08183, Q9UQD0]	DRUG	0.039105489
G03AC06	medroxyprogesterone	C0848558	hypospadias	3	[P03372, P26439, P10275]	METABOLITE	2.59302E-05
C08DA01	verapamil	C0878544	cardiomyopathy	2	[O76082, Q12809]	DRUG_AND_METABOLITE	0.079473486
N05AX12	aripiprazole	C0039503	tendinitis	1	[P35408]	DRUG_AND_METABOLITE	0.01715553
A03FA02	cisapride	C0042109	urticaria	1	[P07550]	DRUG	0.074342707
N07XX02	riluzole	C0027051	myocardial infarction	2	[P04798, P05177]	DRUG	0.091683405
C10AB04	gemfibrozil	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.058723442
D10AA02	methylprednisolone	C0018799	heart disease	1	[P04150]	DRUG_AND_METABOLITE	0.114032233
N03AX11	topiramate	C0017601	glaucoma	1	[O43570]	DRUG	0.06495498
N05AA01	chlorpromazine	C0014130	Endocrine Disorders	6	[Q12809, P32239, Q13639, P35354, P23219, Q9Y5S8]	DRUG	0.114263281
N05BE01	buspirone	C0018802	congestive heart failure	3	[Q9Y2I1, Q12809, P07550]	DRUG_AND_METABOLITE	0.024401265
N05AX12	aripiprazole	C0011849	diabetes mellitus	3	[P08684, P18089, P07550]	DRUG_AND_METABOLITE	0.202985567
N06AX11	mirtazapine	C0149931	migraine	5	[P28223, P21917, P31645, P08684, P28335]	DRUG	1.35032E-05
N06AA04	clomipramine	C0017168	gastroesophageal reflux	2	[P09211, P33261]	DRUG_AND_METABOLITE	0.035742143
N02AA03	hydromorphone	C0242184	hypoxia	1	[Q12809]	DRUG_AND_METABOLITE	0.376648154
C09CA07	telmisartan	C0011991	diarrhea	1	[Q92887]	DRUG	0.03201379
N04BX01	tolcapone	C0027651	tumor	4	[P21964, P06493, P27487, P48147]	METABOLITE	0.390269483
M01AE09	flurbiprofen	C0022116	ischemia	2	[P15121, P35354]	DRUG_AND_METABOLITE	0.028561234
L04AX04	lenalidomide	C0014130	Endocrine Disorders	3	[P35354, P23219, P04798]	DRUG	0.019460121
A02BC04	rabeprazole	C0020456	hyperglycemia	1	[P35354]	DRUG	0.153216013
N05AB03	perphenazine	C0242422	Parkinson	7	[P21917, Q01959, P50406, P08908, P31645, P14416, P35462]	DRUG_AND_METABOLITE	7.44127E-05
N04BC04	ropinirole	C0028754	obesity	1	[P07550]	DRUG	0.118450023
L01XE01	imatinib	C0038358	gastric ulcer	1	[P23219]	DRUG	0.304880892
N07BB04	naltrexone	C0018799	heart disease	2	[P31645, P20813]	DRUG	0.046584723
C07AA15	carteolol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.058400414
C02AC01	clonidine	C0003123	anorexia	6	[P28223, P21917, P21397, P28221, P23975, P14416]	DRUG	1.48976E-07
C01BB01	lidocaine	C0442874	neuropathy	2	[Q9UQD0, P08183]	DRUG	0.030617776
L04AX02	thalidomide	C0032285	pneumonia	3	[P19838, P01375, P35354]	DRUG_AND_METABOLITE	0.053989355
N06AA04	clomipramine	C0021311	infection	5	[P09211, P07550, P04156, Q13936, P17252]	METABOLITE	0.482230875
N06AB03	fluoxetine	C0242422	Parkinson	10	[P21917, P05181, Q01959, P08183, P22303, P50406, P08908, P31645, P14416, P35462]	DRUG	2.33763E-06
C09AA07	benazepril	C0030305	pancreatitis	1	[P42898]	DRUG	0.045119841
N02CC06	eletriptan	C0003123	anorexia	1	[P28221]	DRUG	0.056653613
L02BB03	bicalutamide	C0151950	deep thrombophlebitis	1	[P03372]	DRUG	0.035667691
N05AX08	risperidone	C0037763	spasm	2	[P14867, P21918]	DRUG_AND_METABOLITE	0.010512491
C01EB03	indomethacin	C0022346	jaundice	1	[P22309]	DRUG	0.041008297
C07AG02	carvedilol	C0020625	hyponatremia	1	[P16860]	DRUG	0.013961737
C07AG02	carvedilol	C0020615	hypoglycemia	2	[P15692, P07550]	DRUG_AND_METABOLITE	0.008887027
N04BC05	pramipexole	C0022665	renal tumor	1	[P23975]	DRUG	0.499995859
A02BC04	rabeprazole	C0020473	hyperlipidemia	1	[P23219]	DRUG	0.182729316
M04AA01	allopurinol	C0041582	ulcer	1	[P00813]	METABOLITE	0.098574245
N06DA02	donepezil	C0027051	myocardial infarction	3	[P06276, P11712, P23219]	DRUG	0.017785397
D01AC02	miconazole	C0018681	headache	3	[P29474, P29475, P35228]	DRUG_AND_METABOLITE	0.000570397
S01ED02	betaxolol	C0006266	bronchospasm	1	[P07550]	DRUG_AND_METABOLITE	0.239166635
N06AX16	venlafaxine	C0020615	hypoglycemia	1	[P07550]	DRUG	0.1628433
A02BA01	cimetidine	C0003864	arthritis	1	[Q9H3N8]	DRUG	0.20341662
N04BC04	ropinirole	C0024236	lymphedema	1	[P08684]	DRUG	0.034424934
A02BA02	ranitidine	C0020517	hypersensitivity	3	[P35367, P25021, Q9H3N8]	DRUG	0.000723628
N02CC03	zolmitriptan	C0033975	psychosis	3	[P21397, P28222, P08908]	DRUG	0.000425881
N03AG06	tiagabine	C0014544	epilepsy	1	[Q99259]	DRUG	0.141505689
N06AB08	fluvoxamine	C0010054	coronary artery disease	2	[P08684, P04798]	DRUG_AND_METABOLITE	0.085527439
C10AB02	bezafibrate	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.079937482
M01AE01	ibuprofen	C0011991	diarrhea	4	[P10145, P46098, O60656, P16662]	DRUG	0.000152477
M03BX08	cyclobenzaprine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.082706918
L01BA01	methotrexate	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.128103215
A02BC04	rabeprazole	C0684249	lung cancer	13	[P02768, P35354, Q16678, Q9UNQ0, P08183, P23219, Q16647, P11712, P04798, P33261, P05177, P08684, P10632]	DRUG_AND_METABOLITE	0.000832892
L01BC06	capecitabine	C0020538	hypertension	1	[P11712]	DRUG_AND_METABOLITE	0.323154592
L02BA02	toremifene	C0038454	cerebrovascular accident	4	[P03372, P78417, Q16873, P35354]	METABOLITE	0.040754414
H05BX01	cinacalcet	C0004093	asthenia	1	[P31645]	DRUG	0.020490582
A03FA02	cisapride	C0042024	urinary incontinence	1	[P28223]	DRUG	0.059970595
N05CF03	zaleplon	C0020538	hypertension	2	[P20815, P29275]	DRUG	0.044396476
M01AE09	flurbiprofen	C0017152	gastritis	3	[P10145, P23219, P35354]	DRUG_AND_METABOLITE	0.001421597
J01MA01	ofloxacin	C0007097	carcinoma	7	[P08183, Q92887, P33527, P08684, P05177, P11388, Q12809]	DRUG_AND_METABOLITE	0.112088562
G04CA03	terazosin	C0004093	asthenia	1	[P28223]	DRUG_AND_METABOLITE	0.056501401
N02AA03	hydromorphone	C0008325	cholecystitis	1	[P21439]	DRUG_AND_METABOLITE	0.06589552
N05AB02	fluphenazine	C0013384	dyskinesia	4	[P35498, P14416, P21917, P35462]	DRUG	0.00043088
M01AB08	etodolac	C0027947	neutropenia	2	[P16662, O60656]	DRUG	0.002408295
N02AA03	hydromorphone	C0008311	cholangitis	1	[P21439]	DRUG_AND_METABOLITE	0.055136576
N06AB08	fluvoxamine	C0018524	hallucinations	1	[P08183]	DRUG_AND_METABOLITE	0.102405075
A02BC04	rabeprazole	C0020550	hyperthyroidism	1	[P08183]	METABOLITE	0.13763063
C01EB03	indomethacin	C0014544	epilepsy	5	[P08183, P35498, Q99250, P33527, Q9NY46]	DRUG	0.000553581
A02BC04	rabeprazole	C0020538	hypertension	5	[P05026, Q16647, P05023, Q02928, P11712]	DRUG_AND_METABOLITE	0.031705255
N02CA01	dihydroergotamine	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG	0.028717627
M01AE01	ibuprofen	C0022346	jaundice	1	[P22309]	DRUG	0.054232974
G04CA02	tamsulosin	C0152029	sinus congestion	1	[P35367]	DRUG	0.122499116
N02CC04	rizatriptan	C0003123	anorexia	4	[P28223, P28335, P21397, P28221]	DRUG_AND_METABOLITE	8.36282E-06
L04AX04	lenalidomide	C0151744	myocardial ischemia	1	[P01375]	DRUG	0.078146652
M01AH03	valdecoxib	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.063071299
L01XE02	gefitinib	C0011603	dermatitis	2	[P04629, Q9UKE5]	DRUG_AND_METABOLITE	0.499995859
G03BA03	testosterone	C0005001	benign prostatic hyperplasia	5	[P31213, P05093, P18405, P10275, Q9HB55]	DRUG_AND_METABOLITE	0.001385915
N02CC01	sumatriptan	C0002871	anemia	1	[P02768]	METABOLITE	0.157523633
A03BA01	atropine	C0004134	ataxia	1	[P35498]	DRUG_AND_METABOLITE	0.093529817
A10BA02	metformin	C0041912	upper respiratory tract infection	1	[P27487]	DRUG	0.168674498
D06BB10	imiquimod	C0027051	myocardial infarction	1	[P05177]	DRUG	0.101781344
H02AA02	fludrocortisone	C0017601	glaucoma	1	[P04150]	DRUG_AND_METABOLITE	0.047592614
N05AX12	aripiprazole	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG_AND_METABOLITE	0.013789483
L01AA01	cyclophosphamide	C0019080	hemorrhage	1	[P11712]	DRUG	0.052118018
N06AA01	desipramine	C0042109	urticaria	1	[P07550]	DRUG	0.114588485
M01AB05	diclofenac	C0022658	nephropathy	5	[P02768, P00915, P10145, P00918, P23219]	DRUG_AND_METABOLITE	0.001324082
C07AB03	atenolol	C0018524	hallucinations	1	[P08183]	DRUG	0.065566042
L01BA01	methotrexate	C0243026	sepsis	1	[P47989]	DRUG	0.185392756
N06DA04	galantamine	C0018524	hallucinations	1	[P36544]	DRUG	0.091808164
C08CA05	nifedipine	C0019158	hepatitis	2	[P05181, P11509]	DRUG	0.050365655
A07EA06	budesonide	C0013595	eczema	1	[P05113]	DRUG	0.249802504
N04BX02	entacapone	C0023530	leukopenia	1	[O60656]	DRUG_AND_METABOLITE	0.019687894
N02CA01	dihydroergotamine	C0027051	myocardial infarction	6	[P21554, P07550, P31645, P05177, P08588, P18089]	DRUG	0.036754506
A04AA01	ondansetron	C0242184	hypoxia	3	[P08172, P11229, Q12809]	DRUG	0.261851938
A02BC02	pantoprazole	C0007097	carcinoma	7	[P08183, Q9UNQ0, Q16678, P10632, P04798, P08684, P05177]	DRUG_AND_METABOLITE	0.27830035
M01AB02	sulindac	C0026272	mixed connective tissue disease	1	[P04798]	DRUG	0.233518101
J01MA01	ofloxacin	C0002871	anemia	1	[P02768]	METABOLITE	0.083180344
N06AX21	duloxetine	C0018681	headache	1	[P29475]	DRUG	0.118181872
N04BC02	pergolide	C0020538	hypertension	7	[P35348, P07550, P21728, P28223, P08913, P18089, P08588]	DRUG	0.000274851
N04BB01	amantadine	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.082202439
S01EC01	acetazolamide	C0009951	convulsions	1	[P29972]	DRUG	0.163392504
G03CA03	estradiol	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.030629856
G03AC06	medroxyprogesterone	C0027051	myocardial infarction	4	[P03372, P10275, P04150, P11712]	DRUG_AND_METABOLITE	0.00171444
L02BG04	letrozole	C0027651	tumor	3	[P11511, P08684, P11509]	DRUG	0.098793285
C01BB01	lidocaine	C0018790	cardiac arrest	3	[Q14524, Q12809, Q13936]	DRUG	0.000641197
M01AE09	flurbiprofen	C0022346	jaundice	1	[P22309]	DRUG	0.027818585
P01BC02	mefloquine	C0085584	encephalopathy	1	[P08183]	DRUG	0.05753837
N06AB04	citalopram	C0085649	peripheral edema	1	[P08588]	DRUG	0.036486436
G03CA03	estradiol	C0011570	mental depression	4	[P33261, P08684, P21964, P03372]	DRUG_AND_METABOLITE	0.003004332
C09AA07	benazepril	C0003864	arthritis	1	[P42898]	DRUG	0.044434339
C08DB01	diltiazem	C0011603	dermatitis	2	[P28223, P08908]	DRUG	0.114661067
L01XE03	erlotinib	C0034069	pulmonary fibrosis	3	[P04626, P20783, Q05655]	DRUG_AND_METABOLITE	0.208831113
N05AX12	aripiprazole	C0039239	sinus tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.004954116
C01DA02	nitroglycerin	C0011603	dermatitis	1	[P09211]	METABOLITE	0.215579914
C08CA05	nifedipine	C0019080	hemorrhage	2	[P24557, P11712]	DRUG	0.026275405
N06AA01	desipramine	C0011570	mental depression	11	[P33261, P08684, P28223, P28335, P28222, P50406, P23975, P47898, P08908, P18825, P31645]	DRUG	0
N04BC04	ropinirole	C0032371	poliomyelitis	1	[P07550]	DRUG	0.439129337
M01AH03	valdecoxib	C0018944	hematoma	1	[P11712]	DRUG_AND_METABOLITE	0.11863738
L02BG03	anastrozole	C0027651	tumor	4	[P11511, P08684, P05177, P35348]	METABOLITE	0.280349021
M01AB05	diclofenac	C0151798	hepatic necrosis	1	[P08684]	DRUG	0.280029391
J02AC03	voriconazole	C0917798	cerebral ischemia	1	[P24557]	METABOLITE	0.050504261
G03XA01	danazol	C0030305	pancreatitis	1	[P13500]	DRUG	0.137301926
N04BX02	entacapone	C0011991	diarrhea	1	[O60656]	DRUG_AND_METABOLITE	0.012792437
J05AE03	ritonavir	C0020443	hypercholesterolemia	1	[Q9Y6L6]	DRUG	0.069863749
J01MA07	lomefloxacin	C0027051	myocardial infarction	1	[P05177]	DRUG	0.200077734
H02AB06	prednisolone	C0026848	myopathy	2	[P10275, P04083]	DRUG_AND_METABOLITE	0.03537307
C07AG01	labetalol	C0018802	congestive heart failure	1	[P07550]	DRUG	0.065962289
L01AB01	busulfan	C0030305	pancreatitis	1	[P00325]	METABOLITE	0.081034147
A02BC04	rabeprazole	C1458155	breast neoplasm	7	[Q9UNQ0, P04798, Q16678, P08684, P35354, P08183, P05177]	DRUG_AND_METABOLITE	0.495361915
M01AH01	celecoxib	C0019158	hepatitis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.060200131
N05AH02	clozapine	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG_AND_METABOLITE	0.020271331
N05AX12	aripiprazole	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.004954116
N06AX16	venlafaxine	C0004096	asthma	6	[P07550, P29475, P11229, P29274, P20309, Q14643]	DRUG	0.058537729
C08CA04	nicardipine	C0917798	cerebral ischemia	1	[P62158]	DRUG	0.10852861
N06AX16	venlafaxine	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.012792437
M01AH03	valdecoxib	C0007820	cerebrovascular disorder	2	[P28223, P35354]	DRUG_AND_METABOLITE	0.175756756
C10AB04	gemfibrozil	C0013595	eczema	2	[P37231, Q07869]	DRUG	0.01884128
A02BC04	rabeprazole	C0015695	liver fatty	1	[P02768]	DRUG_AND_METABOLITE	0.13763063
N05AB02	fluphenazine	C0013595	eczema	2	[P28223, P08908]	DRUG	0.102405075
G02CB01	bromocriptine	C0013537	eclampsia	2	[P07550, P36544]	DRUG	0.160679998
N06AX21	duloxetine	C0018524	hallucinations	6	[P08183, P36544, P35498, Q99250, P04156, Q9NY46]	DRUG	0.000556622
N05AH02	clozapine	C0027051	myocardial infarction	10	[P21554, P13945, P04798, P07550, P11712, P33261, P31645, P05177, P08588, P18089]	DRUG_AND_METABOLITE	0.006342878
C10AA06	cerivastatin	C0023530	leukopenia	2	[Q92887, P08183]	DRUG_AND_METABOLITE	0.004137789
N05AH02	clozapine	C0027059	myocarditis	2	[Q12809, P08588]	DRUG_AND_METABOLITE	0.128052648
N05AX12	aripiprazole	C0242422	Parkinson	8	[P21917, Q01959, P21554, P50406, P08908, P31645, P14416, P35462]	DRUG_AND_METABOLITE	0.000276076
N04BC02	pergolide	C0020615	hypoglycemia	1	[P07550]	DRUG	0.07985866
M01AB15	ketorolac	C0004093	asthenia	1	[P35354]	DRUG	0.031878908
M01AB15	ketorolac	C0004096	asthma	3	[P10145, P35354, P23219]	DRUG	0.027964493
N04BD01	selegiline	C0013384	dyskinesia	2	[P14416, P35462]	METABOLITE	0.028957228
P01BC02	mefloquine	C0012833	dizziness	1	[P29274]	DRUG	0.010781267
C10AA02	lovastatin	C0026848	myopathy	3	[Q9Y6L6, P16219, P29475]	METABOLITE	0.250410781
L01XE01	imatinib	C0003123	anorexia	1	[Q16620]	DRUG	0.399419516
A02BA01	cimetidine	C0011991	diarrhea	1	[P46098]	DRUG	0.065563767
N05AB03	perphenazine	C0037763	spasm	1	[P21918]	DRUG	0.052191974
B01AC05	ticlopidine	C0009319	colitis	1	[P35354]	DRUG_AND_METABOLITE	0.218238202
N06DA03	rivastigmine	C0029456	osteoporosis	1	[P08684]	DRUG	0.060318772
L04AA13	leflunomide	C0023895	liver disease	1	[P03956]	DRUG	0.099257725
G03DA04	progesterone	C0021311	infection	4	[P03372, P11413, Q96RI1, P04150]	DRUG_AND_METABOLITE	0.476743942
S01ED02	betaxolol	C0011849	diabetes mellitus	2	[P13945, P07550]	DRUG_AND_METABOLITE	0.082415968
C08CA04	nicardipine	C1527304	allergic reaction	1	[O75762]	DRUG	0.098727853
N05AH02	clozapine	C0011849	diabetes mellitus	6	[P11712, P08684, P18089, P13945, P07550, P10632]	DRUG	0.063596471
N06AB06	sertraline	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.00358369
N06AX16	venlafaxine	C0009319	colitis	5	[P08183, P31645, Q14524, P46098, P41595]	DRUG	0.028123725
L04AX04	lenalidomide	C0151908	dry skin	2	[Q07343, P01375]	DRUG	0.023434064
L01XX05	hydroxyurea	C0019080	hemorrhage	1	[P14780]	METABOLITE	0.034424934
C02CA01	prazosin	C0030305	pancreatitis	2	[Q99895, P04798]	DRUG	0.071951191
C10AA03	pravastatin	C0151798	hepatic necrosis	2	[Q92887, P08684]	DRUG_AND_METABOLITE	0.031745841
N06AX21	duloxetine	C0035305	retinal detachment	1	[P25929]	DRUG	0.064097201
N05AH04	quetiapine	C0004096	asthma	5	[P07550, Q9Y271, P43115, P11229, P20309]	DRUG	0.062228737
N05AH04	quetiapine	C0004093	asthenia	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.009279632
D10AA02	methylprednisolone	C0018802	congestive heart failure	1	[P08235]	DRUG_AND_METABOLITE	0.05003687
N06BA04	methylphenidate	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.004167423
C09CA07	telmisartan	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.029015714
C10AA02	lovastatin	C0019158	hepatitis	1	[P05181]	METABOLITE	0.422107082
N07XX02	riluzole	C0032584	polyps	4	[P05177, O15554, Q9UNQ0, P04798]	DRUG	0.137481759
A02BA01	cimetidine	C0016059	fibrosis	1	[P05181]	DRUG	0.281249735
G02CB01	bromocriptine	C0013604	edema	1	[P08588]	DRUG	0.05856492
C01BB01	lidocaine	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.009869111
A02BC01	omeprazole	C0029456	osteoporosis	2	[P08684, P04798]	DRUG_AND_METABOLITE	0.042607245
N05BE01	buspirone	C0014394	enuresis	2	[P28223, P21917]	DRUG_AND_METABOLITE	0.013338373
L04AX01	azathioprine	C0021311	infection	8	[P06730, P78362, P47989, P17252, Q16539, P27361, P16220, P24666]	METABOLITE	0.08284802
C01BD01	amiodarone	C0009806	constipation	1	[Q14524]	DRUG	0.03490134
M01AB15	ketorolac	C0035078	renal failure	1	[P41222]	DRUG	0.083870425
L01XE01	imatinib	C0878544	cardiomyopathy	2	[P52564, Q16539]	DRUG	0.417871609
M01AB05	diclofenac	C0151827	eye pain	1	[P10145]	DRUG_AND_METABOLITE	0.07797371
N06BA07	modafinil	C0149931	migraine	1	[P08684]	DRUG	0.052242123
N03AX09	lamotrigine	C0030305	pancreatitis	1	[Q99895]	DRUG	0.103777387
D10AA02	methylprednisolone	C0085660	Aseptic necrosis	1	[P08183]	DRUG_AND_METABOLITE	0.025394378
S01AA14	penicillin G	C0231528	myalgia	1	[Q9Y6L6]	DRUG	0.178422089
C02CA04	doxazosin	C0007820	cerebrovascular disorder	1	[P28223]	METABOLITE	0.193013165
C01BB01	lidocaine	C0019080	hemorrhage	1	[P11712]	DRUG	0.093529817
N06AB05	paroxetine	C0678222	breast cancer	4	[P08183, P20813, Q01959, P10632]	DRUG	0.49704527
A04AA01	ondansetron	C0015672	fatigue	1	[P28223]	DRUG	0.078232634
N05AH02	clozapine	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG_AND_METABOLITE	2.47627E-05
N05CF03	zaleplon	C0009319	colitis	1	[P03956]	METABOLITE	0.112133252
M01AC06	meloxicam	C0021311	infection	3	[P35354, P23219, P09917]	DRUG	0.029823411
R06AD02	promethazine	C0004134	ataxia	1	[P35498]	DRUG	0.12745769
M01AE02	naproxen	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG	0.14162194
C01BC03	propafenone	C0020538	hypertension	2	[P22460, P11712]	DRUG	0.06570642
N02CA01	dihydroergotamine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	3.59294E-07
D05BB02	acitretin	C0030305	pancreatitis	1	[P35354]	METABOLITE	0.149633234
N04BD01	selegiline	C0005747	blepharospasm	1	[P14416]	DRUG_AND_METABOLITE	0.093424978
N06AB04	citalopram	C0007820	cerebrovascular disorder	1	[P28223]	DRUG	0.233286432
A04AA01	ondansetron	C0020517	hypersensitivity	2	[P41595, P35367]	DRUG	0.059078532
N02AA03	hydromorphone	C0003123	anorexia	6	[P21964, P21917, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	4.90821E-07
N06AA10	nortriptyline	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.010316539
N04BC04	ropinirole	C0029456	osteoporosis	1	[P08684]	DRUG	0.151656571
C01BC04	flecainide	C0003123	anorexia	1	[P14416]	METABOLITE	0.0459356
L01XE02	gefitinib	C0242184	hypoxia	24	[P31749, Q16539, Q02763, P37173, P36897, O60674, P54646, P06239, P43405, P12931, P17948, Q02750, P36507, P23458, P35968, Q9H4B4, P04626, Q13131, P17612, P68400, P28482, O14965, P27361, Q05655]	DRUG_AND_METABOLITE	0.000420364
R01AC03	azelastine	C0003873	rheumatoid arthritis	2	[P05177, P04798]	DRUG	0.097597963
N06AB03	fluoxetine	C0042514	ventricular tachycardia	1	[P08588]	DRUG	0.05003687
C09AA04	perindopril	C0004604	back pain	1	[P12821]	DRUG_AND_METABOLITE	0.002297402
B01AC04	clopidogrel	C0034065	pulmonary embolism	1	[Q9H244]	DRUG	0.019239124
J01FA09	clarithromycin	C0018524	hallucinations	2	[P08183, P33527]	DRUG	0.012425662
N06AA11	protriptyline	C0001824	agranulocytosis	1	[P08183]	DRUG	0.122744
L04AA06	mycophenolic acid	C0027651	tumor	2	[P37231, P22309]	DRUG_AND_METABOLITE	0.31590567
N04BC02	pergolide	C0003123	anorexia	5	[P28223, P21917, P28335, P28221, P14416]	DRUG_AND_METABOLITE	4.24904E-06
J05AF01	zidovudine	C0015672	fatigue	1	[P28223]	METABOLITE	0.036033671
R03AC12	salmeterol	C0009443	common cold	1	[P07550]	DRUG	0.213625993
L04AA06	mycophenolic acid	C0015230	rash	1	[P37231]	DRUG_AND_METABOLITE	0.069716619
N05AB06	trifluoperazine	C0031511	pheochromocytoma	24	[P05177, P11509, P32238, P08183, P04156, P05771, Q12809, Q09470, P35354, P30874, P32239, P20815, P05181, P04629, P23975, P10275, P17252, P29475, P09917, P36544, P26447, Q9Y5S8, P17405, P47989]	DRUG	0.303471269
N02AA03	hydromorphone	C0011206	delirium	1	[P21554]	METABOLITE	0.049355201
R06AD02	promethazine	C0004093	asthenia	1	[P28223]	DRUG_AND_METABOLITE	0.057302129
R06AD02	promethazine	C0004096	asthma	3	[P05362, P11229, P20309]	DRUG	0.126621507
C07AB07	bisoprolol	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.012425662
G03CA03	estradiol	C0699744	ear infection	1	[P03372]	DRUG_AND_METABOLITE	0.499995859
L01XE01	imatinib	C0002874	aplastic anemia	4	[P06748, O14757, P60953, P19525]	DRUG	0.177569412
L01XE01	imatinib	C0002871	anemia	1	[P02768]	DRUG	0.441292771
N06AB05	paroxetine	C1458140	bleeding diathesis	1	[P11712]	DRUG	0.100741343
C03DB02	triamterene	C0011991	diarrhea	1	[P37088]	DRUG	0.028748417
N05CF01	zopiclone	C0020473	hyperlipidemia	1	[P23219]	DRUG	0.105436928
N06AB05	paroxetine	C1458155	breast neoplasm	4	[P08183, P20813, Q01959, P23975]	DRUG_AND_METABOLITE	0.499643303
N05AB06	trifluoperazine	C0026266	mitral insufficiency	11	[P05362, Q12809, P48544, P23219, P31645, P35354, P08588, P11712, P07550, P20813, P23975]	DRUG_AND_METABOLITE	0.001103208
M05BA04	alendronate	C0023418	leukemia	2	[P48736, P00492]	DRUG	0.132400054
L04AX04	lenalidomide	C0003864	arthritis	3	[O14788, P19838, P01375]	DRUG	0.003826662
N04BC05	pramipexole	C0027051	myocardial infarction	4	[P07550, P31645, P08588, P18089]	DRUG	0.071696172
N06AX05	trazodone	C1527304	allergic reaction	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG	7.96128E-05
R03DC01	zafirlukast	C1458140	bleeding diathesis	1	[P11712]	DRUG_AND_METABOLITE	0.134991257
C09AA03	lisinopril	C0004238	atrial fibrillation	1	[P12821]	DRUG	0.030969403
D05BB02	acitretin	C0010709	cyst	6	[P35354, P10826, P11511, P34995, P05067, P29373]	METABOLITE	0.127783868
N05AX08	risperidone	C0037315	sleep apnea	1	[P31645]	DRUG_AND_METABOLITE	0.040753047
C09CA07	telmisartan	C0011603	dermatitis	2	[P37231, Q07869]	DRUG	0.044131635
N03AX16	pregabalin	C0010709	cyst	1	[Q01650]	DRUG	0.403116106
C07AB02	metoprolol	C0020615	hypoglycemia	1	[P07550]	DRUG_AND_METABOLITE	0.052057421
N06AX06	nefazodone	C1527304	allergic reaction	3	[P41595, Q01959, P35367]	DRUG_AND_METABOLITE	0.002877124
N06AA04	clomipramine	C0022104	irritable bowel syndrome	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.011731805
P01AX06	atovaquone	C0003123	anorexia	9	[P28223, P21964, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	METABOLITE	4.03358E-07
A02BA01	cimetidine	C0015230	rash	1	[P28223]	DRUG	0.277558428
C07AA05	propranolol	C0003123	anorexia	5	[P28223, P28335, P28221, P31645, P14416]	DRUG	1.54047E-05
N06AA04	clomipramine	C0022116	ischemia	3	[P05181, P29475, P29274]	METABOLITE	0.062319473
N03AX12	gabapentin	C0027651	tumor	2	[Q01650, P54687]	DRUG_AND_METABOLITE	0.471662227
L01XE01	imatinib	C0030305	pancreatitis	2	[P15056, P00918]	DRUG	0.445462641
G03CA03	estradiol	C0008031	chest pain	1	[P02768]	DRUG_AND_METABOLITE	0.040229277
J05AF01	zidovudine	C0027121	myositis	1	[P61073]	DRUG	0.085892844
N06AA09	amitriptyline	C0018681	headache	1	[P05362]	METABOLITE	0.126061203
H02AB06	prednisolone	C0027051	myocardial infarction	6	[P03372, P10275, P04278, P04150, Q92731, P33261]	METABOLITE	0.001665104
M01AH01	celecoxib	C0018524	hallucinations	1	[P33527]	DRUG	0.193131417
N01BB09	ropivacaine	C0013384	dyskinesia	1	[P35498]	METABOLITE	0.102516927
N03AF01	carbamazepine	C0020538	hypertension	4	[P20815, P21728, P28223, P11712]	DRUG	0.026701362
N05AH04	quetiapine	C0003864	arthritis	1	[Q9H3N8]	DRUG_AND_METABOLITE	0.276586801
N03AX14	levetiracetam	C0027947	neutropenia	2	[Q92887, P08183]	DRUG	0.000885227
J02AC03	voriconazole	C0023895	liver disease	1	[P08684]	DRUG	0.089912296
N03AX11	topiramate	C0029456	osteoporosis	1	[P08684]	DRUG	0.117444075
N03AF01	carbamazepine	C0020517	hypersensitivity	1	[P35367]	DRUG	0.107357655
N03AB04	mephenytoin	C0036572	seizures	2	[Q99250, P35498]	DRUG_AND_METABOLITE	0.014025764
N05AX08	risperidone	C0003864	arthritis	1	[Q9H3N8]	DRUG_AND_METABOLITE	0.276586801
G03AC06	medroxyprogesterone	C0038454	cerebrovascular accident	1	[P03372]	DRUG_AND_METABOLITE	0.101778723
N05AX12	aripiprazole	C0242184	hypoxia	3	[P08172, P11229, Q12809]	DRUG_AND_METABOLITE	0.213698998
C10AB05	fenofibrate	C0027051	myocardial infarction	4	[P37231, Q07869, P08246, P11712]	DRUG	0.003094049
B01AC07	dipyridamole	C0231218	malaise	1	[Q08499]	DRUG	0.016169699
N04BD01	selegiline	C0032285	pneumonia	1	[Q16853]	DRUG_AND_METABOLITE	0.163862268
N05AH04	quetiapine	C0020473	hyperlipidemia	1	[P07550]	DRUG	0.223959193
A04AD12	aprepitant	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.034424934
G03AC06	medroxyprogesterone	C0033687	proteinuria	1	[P08235]	METABOLITE	0.035047926
R03AC12	salmeterol	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.210928081
L01XE01	imatinib	C0030354	papilloma	77	[P05177, P31749, Q04912, P42336, P06213, P08183, P24941, P29317, P00533, O43570, P04626, P06748, P10721, P00519, P08581, P29597, P29323, Q02763, P37173, P36897, P53350, O60674, P49841, Q05397, P19525, P22455, Q16539, P21802, P06239, P68400, P28482, P53667, P45983, P22607, P27361, Q13164, Q9UM73, P45985, P07333, P24723, O14757, P16234, Q16790, P43405, P08069, P15056, P36894, Q15831, P07949, O14965, P12931, P53355, P07948, Q9UNQ0, Q00526, Q13873, P06241, O95835, P20815, Q13882, P04629, P35916, P21709, Q02750, P35968, P31751, P36507, Q13547, Q14289, P17252, Q9Y243, Q9UBN7, P49840, P11362, P52333, Q9NRM7, P23458]	DRUG	0.000289157
J05AF03	zalcitabine	C0026848	myopathy	1	[O00142]	METABOLITE	0.16306186
C10AA03	pravastatin	C0011991	diarrhea	1	[Q92887]	DRUG_AND_METABOLITE	0.042804682
L01BA01	methotrexate	C0001824	agranulocytosis	3	[Q92887, Q9NPD5, P08183]	DRUG	0.000673189
N06AA02	imipramine	C0004134	ataxia	2	[P35498, Q14643]	METABOLITE	0.096910793
N04BD01	selegiline	C0149931	migraine	4	[P28223, P31645, P08684, P28335]	DRUG_AND_METABOLITE	0.000327066
C02AC01	clonidine	C0004093	asthenia	1	[P28223]	DRUG	0.042475697
C04AD03	pentoxifylline	C0006266	bronchospasm	3	[P01375, P29274, Q08499]	DRUG	0.015717272
A02BC04	rabeprazole	C0037287	skin nodule	1	[P35354]	DRUG	0.153216013
P02CA01	mebendazole	C0001824	agranulocytosis	1	[P08183]	DRUG	0.032885129
L01XE01	imatinib	C0015230	rash	1	[P04629]	DRUG	0.499995859
A02BC04	rabeprazole	C0011849	diabetes mellitus	6	[P11712, P47712, P08684, P35354, P02768, P10632]	DRUG_AND_METABOLITE	0.012425662
N06AA09	amitriptyline	C0020538	hypertension	14	[P20815, P35348, P13945, P07550, P21728, O15244, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	0.000384154
J05AF01	zidovudine	C0002871	anemia	1	[P02768]	DRUG	0.091184812
N06AA09	amitriptyline	C0020565	breast enlargement	2	[P05362, Q9Y210]	DRUG	0.110876596
J05AE03	ritonavir	C0232726	tenesmus	1	[Q9Y6L6]	DRUG	0.090670562
N04BC05	pramipexole	C0043144	wheezing	3	[P07550, P11229, P20309]	DRUG	0.114580337
M01AE02	naproxen	C0011860	type 2 diabetes	7	[P11712, P18031, P35354, P02768, P18089, Q05469, P10632]	DRUG	0.005245041
C09AA02	enalapril	C0039231	tachycardia	1	[P12821]	DRUG_AND_METABOLITE	0.018943768
L02AB01	megestrol	C0024115	lung disorder	2	[P08183, P04150]	DRUG	0.025816147
A03FA02	cisapride	C0020615	hypoglycemia	1	[P07550]	DRUG	0.09539256
A08AA10	sibutramine	C0027051	myocardial infarction	1	[P31645]	DRUG_AND_METABOLITE	0.29926214
N03AF01	carbamazepine	C0020456	hyperglycemia	1	[P35354]	METABOLITE	0.110876596
N04AC01	benztropine	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.017771337
N06AA04	clomipramine	C0442874	neuropathy	2	[Q9UQD0, P08183]	DRUG_AND_METABOLITE	0.129936284
L04AA06	mycophenolic acid	C0027947	neutropenia	2	[O60656, P22309]	DRUG_AND_METABOLITE	0.000516726
N03AF01	carbamazepine	C0004093	asthenia	2	[P28223, P35354]	METABOLITE	0.002877124
N01AH01	fentanyl	C0042024	urinary incontinence	1	[P28223]	DRUG	0.036145855
C01BD01	amiodarone	C0030591	paroxysmal ventricular tachycardia	2	[Q14524, P08588]	DRUG	0.001248928
N06AX05	trazodone	C0033975	psychosis	7	[P35462, P28223, P21917, Q13639, P28222, P31645, P08908]	DRUG_AND_METABOLITE	7.62017E-06
N05CD08	midazolam	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.046530938
B01AC07	dipyridamole	C0008033	pleuritic pain	1	[Q08499]	DRUG	0.031878908
N04BX01	tolcapone	C0019080	hemorrhage	1	[P11712]	DRUG	0.05003026
G03DA04	progesterone	C0041912	upper respiratory tract infection	3	[P03372, P11413, Q96RI1]	DRUG	0.488202011
N05AH04	quetiapine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.009279632
N06DX01	memantine	C0011991	diarrhea	1	[P46098]	DRUG	0.040283843
N03AF02	oxcarbazepine	C0013595	eczema	1	[Q16548]	DRUG	0.096195732
N05CF03	zaleplon	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.168492591
N06BA01	amphetamine	C0086769	panic attacks	6	[P08908, P28223, P21397, P46098, P31645, P23975]	DRUG_AND_METABOLITE	7.95802E-06
N05AA01	chlorpromazine	C0002871	anemia	2	[P05362, P02768]	DRUG_AND_METABOLITE	0.146825865
N04BC04	ropinirole	C0152029	sinus congestion	2	[P35367, P08588]	DRUG	0.031705255
N04BC04	ropinirole	C0152018	esophageal cancer	2	[P08684, P05177]	DRUG	0.466233759
R03AC13	formoterol	C0041912	upper respiratory tract infection	1	[P07550]	DRUG	0.210928081
N02CC03	zolmitriptan	C0020538	hypertension	3	[P21728, P08913, P18089]	DRUG	0.013755114
C07AB03	atenolol	C0035078	renal failure	1	[P08183]	DRUG	0.063874646
N06AX21	duloxetine	C0003123	anorexia	9	[P28223, P21917, P28335, P21397, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	9.85161E-08
D05BB02	acitretin	C0038454	cerebrovascular accident	2	[P05067, P35354]	METABOLITE	0.056872592
G03BA03	testosterone	C0023530	leukopenia	2	[P22309, P08183]	METABOLITE	0.048802215
D06AA01	demeclocycline	C0038325	Stevens - Johnson syndrome	1	[P08253]	DRUG	0.021841092
N06DA03	rivastigmine	C0024115	lung disorder	1	[P31645]	DRUG	0.113598475
N06DA03	rivastigmine	C0024117	COPD	1	[P31645]	DRUG	0.093159412
N05AH04	quetiapine	C0020538	hypertension	11	[P20815, P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG	0.00012305
N05AE04	ziprasidone	C0015230	rash	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG	0.003689443
J01MA01	ofloxacin	C0001824	agranulocytosis	2	[Q92887, P08183]	DRUG	0.004222847
N05AH04	quetiapine	C0020517	hypersensitivity	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	0.000260019
M03BX01	baclofen	C0018524	hallucinations	3	[P35498, Q99250, Q9NY46]	DRUG	0.002121582
C08CA05	nifedipine	C0042024	urinary incontinence	1	[P28223]	DRUG	0.07347151
M01AE09	flurbiprofen	C0021311	infection	5	[P10145, P35354, P23219, P05067, P24666]	DRUG	0.050504261
C10AA04	fluvastatin	C0013595	eczema	3	[P37231, P21731, Q07869]	METABOLITE	0.004927408
D10AA02	methylprednisolone	C0026848	myopathy	1	[P10275]	DRUG_AND_METABOLITE	0.06174012
N05AH04	quetiapine	C0020550	hyperthyroidism	2	[P07550, P08183]	DRUG	0.0464334
C10AA05	atorvastatin	C0231528	myalgia	1	[Q9Y6L6]	DRUG_AND_METABOLITE	0.085892844
A02BC03	lansoprazole	C0032584	polyps	5	[P05177, P08183, Q9UNQ0, Q16678, P04798]	DRUG	0.206884445
N06DX01	memantine	C0011849	diabetes mellitus	2	[P06276, O15245]	DRUG	0.092998912
N05CF01	zopiclone	C0020538	hypertension	1	[P11712]	DRUG	0.282129303
N07BA03	varenicline	C0018524	hallucinations	1	[P36544]	DRUG	0.058723442
N03AG01	valproic acid	C0020538	hypertension	3	[P20815, P13726, P11712]	DRUG	0.132875318
M01AE12	oxaprozin	C0018834	heartburn	1	[P23219]	DRUG	0.012792437
G04BE08	tadalafil	C0038454	cerebrovascular accident	1	[Q08499]	DRUG	0.192432613
N06AB05	paroxetine	C0085649	peripheral edema	1	[P08588]	DRUG	0.042974428
N04BX01	tolcapone	C0027051	myocardial infarction	1	[P11712]	DRUG	0.222747961
N06AA06	trimipramine	C0020565	breast enlargement	1	[P05362]	METABOLITE	0.29910529
L01BA01	methotrexate	C0029456	osteoporosis	2	[P42898, Q9NSA0]	DRUG	0.045540675
N02BA11	diflunisal	C0030920	peptic ulcer	2	[P35354, P23219]	DRUG	0.005601404
N05AE04	ziprasidone	C0009806	constipation	4	[A5X5Y0, P46098, P41595, P31645]	DRUG_AND_METABOLITE	1.12325E-05
M03BX08	cyclobenzaprine	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.153888589
N07BB04	naltrexone	C0003123	anorexia	3	[P41143, P31645, P23975]	DRUG	0.000200103
M01AH03	valdecoxib	C0011991	diarrhea	2	[P46098, O60656]	DRUG_AND_METABOLITE	0.01165386
N01AH01	fentanyl	C0242184	hypoxia	1	[Q12809]	DRUG	0.245723481
N06BC01	caffeine	C0007784	cerebral hemorrhage	1	[Q08499]	METABOLITE	0.302797933
J01AA08	minocycline	C0003864	arthritis	4	[P01584, P08254, P15692, Q9UM07]	DRUG	0.000627876
N06AA06	trimipramine	C0020538	hypertension	16	[P20815, P35348, P13945, P07550, P21728, O15244, P31645, Q9Y2I1, P28223, P11712, P23975, P08913, P18089, P08588, Q12791, P29475]	METABOLITE	0.000116341
C09CA07	telmisartan	C0011849	diabetes mellitus	3	[P37231, Q07869, P30556]	DRUG	0.015717272
N02CC01	sumatriptan	C0032019	pituitary tumors	3	[P03372, P08183, P14416]	DRUG	0.020237105
G03CA03	estradiol	C0016977	gallbladder disease	1	[P22309]	DRUG	0.133313088
N03AF01	carbamazepine	C0004134	ataxia	1	[P35498]	DRUG	0.097296676
N05AA01	chlorpromazine	C0019159	hepatitis infectious	5	[P05181, P23219, P35354, P11509, P02768]	DRUG_AND_METABOLITE	0.010525886
N06AA10	nortriptyline	C0015230	rash	5	[P07550, P28223, P08908, P31645, P17405]	DRUG	0.016169699
R03DC01	zafirlukast	C0004093	asthenia	1	[P28223]	DRUG_AND_METABOLITE	0.064996834
C01BD01	amiodarone	C0023895	liver disease	1	[P08684]	DRUG	0.157350877
C01BD01	amiodarone	C0023890	cirrhosis	1	[P08684]	DRUG	0.190102925
N06AB04	citalopram	C0152029	sinus congestion	2	[P35367, P08588]	DRUG	0.030334419
N05AH04	quetiapine	C0020615	hypoglycemia	1	[P07550]	DRUG	0.137002057
M01AH03	valdecoxib	C0027051	myocardial infarction	8	[P35354, P21554, P11712, P33261, P31645, P07451, P23219, P18089]	DRUG_AND_METABOLITE	0.004408314
N03AX16	pregabalin	C0007097	carcinoma	1	[Q01650]	DRUG	0.470490328
S01AA14	penicillin G	C0009951	convulsions	4	[P35498, P08183, Q99250, Q9NY46]	DRUG	0.019239124
N05BE01	buspirone	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	9.85161E-08
C08DA01	verapamil	C0004093	asthenia	2	[P31645, P28223]	DRUG	0.00739731
H02AB06	prednisolone	C0085660	Aseptic necrosis	1	[P08183]	DRUG_AND_METABOLITE	0.057088716
C09AA03	lisinopril	C0004096	asthma	1	[P12821]	DRUG	0.092356341
C09AA03	lisinopril	C0004093	asthenia	1	[P12821]	DRUG	0.012425662
C08CA02	felodipine	C0012833	dizziness	1	[P29274]	DRUG_AND_METABOLITE	0.022963468
N05AA01	chlorpromazine	C0686347	tardive dyskinesia	2	[P35498, Q12791]	DRUG	0.026665834
M01AE09	flurbiprofen	C0021400	Influenza	1	[P10145]	DRUG	0.07985866
B05BC01	mannitol	C0027720	nephrosis	1	[P29460]	METABOLITE	0.276967286
N06AB05	paroxetine	C0151827	eye pain	1	[O60840]	DRUG	0.055136576
N04BC05	pramipexole	C0027430	nasal polyps	1	[P23975]	DRUG	0.499995859
S01AA14	penicillin G	C0018524	hallucinations	4	[P08183, P35498, Q99250, Q9NY46]	DRUG	0.001923348
M01AH02	rofecoxib	C0022661	chronic renal failure	2	[P35348, P35368]	DRUG_AND_METABOLITE	0.081233454
C09AA04	perindopril	C0009782	connective tissue disorders	1	[P12821]	DRUG_AND_METABOLITE	0.010569187
N02CC06	eletriptan	C0019080	hemorrhage	1	[P11712]	DRUG	0.052118018
M01AH01	celecoxib	C0018801	heart failure	2	[Q9Y2I1, Q16539]	DRUG	0.06389105
M01AH01	celecoxib	C0018802	congestive heart failure	2	[Q9Y2I1, Q16539]	DRUG	0.06389105
L04AX04	lenalidomide	C0032300	lobar pneumonia	3	[P19838, P01375, P35354]	DRUG	0.000732099
A01AC01	triamcinolone	C0043144	wheezing	1	[P04150]	DRUG	0.077274451
H02AB06	prednisolone	C0027651	tumor	19	[Q9UNQ0, P11511, P08684, P03372, P08183, P06401, Q92731, P04278, P08235, P46721, P10275, P04083, P04150, P20815, P10632, P11509, P15104, Q09470, P33261]	METABOLITE	0.000810085
C10AB04	gemfibrozil	C0007784	cerebral hemorrhage	1	[P37231]	DRUG	0.101078094
J05AF02	didanosine	C0442874	neuropathy	1	[P54098]	METABOLITE	0.108816906
L04AA06	mycophenolic acid	C0004096	asthma	1	[P37231]	DRUG_AND_METABOLITE	0.105539171
H02AB07	prednisone	C0026848	myopathy	2	[P10275, P04083]	DRUG_AND_METABOLITE	0.03537307
N06AB05	paroxetine	C0085762	alcohol abuse	7	[P28223, P31645, P21728, P08908, P14416, P08172, P35372]	METABOLITE	0
N03AE01	clonazepam	C0003123	anorexia	1	[P21397]	DRUG_AND_METABOLITE	0.086416771
C08DB01	diltiazem	C0003123	anorexia	1	[P28223]	DRUG	0.092356341
A02BC03	lansoprazole	C0022346	jaundice	1	[Q9Y6L6]	METABOLITE	0.025953097
N05AX08	risperidone	C0020615	hypoglycemia	1	[P07550]	DRUG_AND_METABOLITE	0.137002057
L04AX04	lenalidomide	C0032285	pneumonia	3	[P19838, P01375, P35354]	DRUG	0.001727159
C04AD03	pentoxifylline	C0036974	shock	1	[P01375]	DRUG_AND_METABOLITE	0.039806384
G03CA03	estradiol	C0032776	postmenopausal bleeding	1	[P11712]	DRUG_AND_METABOLITE	0.163956105
G03BA03	testosterone	C0031212	personality disorder	1	[P21397]	DRUG_AND_METABOLITE	0.05003687
L02BB03	bicalutamide	C0010709	cyst	3	[P06401, P03372, P10275]	DRUG_AND_METABOLITE	0.035667691
N03AA03	primidone	C0015672	fatigue	1	[P35354]	METABOLITE	0.057302129
C09AA07	benazepril	C0004604	back pain	1	[P12821]	DRUG_AND_METABOLITE	0.002297402
C02CA04	doxazosin	C1458155	breast neoplasm	3	[P04818, P08183, Q12809]	DRUG	0.470803739
N06BA04	methylphenidate	C0010709	cyst	1	[P23975]	DRUG_AND_METABOLITE	0.499995859
M01AH03	valdecoxib	C0011849	diabetes mellitus	4	[P11712, P08684, P35354, P18089]	DRUG_AND_METABOLITE	0.086884165
G03DA04	progesterone	C0013390	dysmenorrhea	1	[P04798]	DRUG_AND_METABOLITE	0.044087091
C01CA24	epinephrine	C0010054	coronary artery disease	3	[P08684, P13945, P10275]	METABOLITE	0.043503908
N02AX02	tramadol	C0029456	osteoporosis	1	[P08684]	DRUG	0.094016143
J01MA07	lomefloxacin	C0001824	agranulocytosis	1	[Q92887]	DRUG	0.037092814
N06BA01	amphetamine	C0021311	infection	3	[P14780, P07550, P14174]	METABOLITE	0.496050595
L01CB01	etoposide	C0243026	sepsis	1	[P42574]	DRUG_AND_METABOLITE	0.13345508
S01AA14	penicillin G	C0018621	seasonal allergic rhinitis	1	[Q01959]	DRUG	0.163392504
J01AA02	doxycycline	C0009443	common cold	4	[P04156, P08254, P08253, O14746]	DRUG	0.042475697
N06DA04	galantamine	C0009951	convulsions	1	[P36544]	DRUG	0.163392504
N06AB05	paroxetine	C0151744	myocardial ischemia	1	[P08588]	DRUG	0.114588485
N06AA09	amitriptyline	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.092611701
C09CA06	candesartan	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.032885129
N05AD01	haloperidol	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.030267383
C09AA01	captopril	C0035078	renal failure	3	[P12821, P08183, P00797]	DRUG	0.001408701
L04AX04	lenalidomide	C0007097	carcinoma	11	[P05181, P35354, O14788, P19838, P01375, P23219, P21802, P27815, P20815, P04798, P05177]	DRUG	0.009289734
A02BC04	rabeprazole	C0007784	cerebral hemorrhage	1	[P35354]	DRUG	0.289609293
C09CA04	irbesartan	C0699744	ear infection	1	[P23219]	DRUG_AND_METABOLITE	0.297472422
N05AB03	perphenazine	C0020517	hypersensitivity	3	[P41595, Q01959, P35367]	DRUG	0.003694405
C01CA24	epinephrine	C0007784	cerebral hemorrhage	2	[P28223, P07550]	DRUG_AND_METABOLITE	0.071781449
M01AE02	naproxen	C0038454	cerebrovascular accident	2	[P28223, P35354]	DRUG	0.162947188
N05AB02	fluphenazine	C0242422	Parkinson	8	[P21917, P05181, P08183, P50406, P08908, Q9UQD0, P14416, P35462]	DRUG	2.54371E-05
G04BE07	apomorphine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.070199651
N05AH02	clozapine	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.013399503
N02CC01	sumatriptan	C0002103	allergic rhinitis	1	[P11712]	METABOLITE	0.202920474
N07AX01	pilocarpine	C0149931	migraine	1	[P08684]	DRUG	0.040753047
N05AB06	trifluoperazine	C0003123	anorexia	10	[P28223, P21917, P28335, P21397, P28221, P41143, P31645, P23975, P14416, Q16620]	DRUG	9.85161E-08
N05AB03	perphenazine	C0020538	hypertension	8	[P35348, P21728, P31645, P28223, P11712, P23975, P08913, P18089]	DRUG	0.000195869
M01AE02	naproxen	C0011991	diarrhea	2	[P46098, P16662]	DRUG	0.014022221
N02BA11	diflunisal	C0017152	gastritis	2	[P23219, P35354]	DRUG	0.006123104
J05AF05	lamivudine	C0024299	lymphoma	1	[P27707]	DRUG	0.236653606
J01FA10	azithromycin	C0151798	hepatic necrosis	2	[P21439, P08684]	DRUG_AND_METABOLITE	0.028105805
J05AF03	zalcitabine	C0003864	arthritis	1	[P61073]	DRUG	0.165962026
N06AA01	desipramine	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.089551563
M01AH03	valdecoxib	C0027651	tumor	15	[P08684, P35354, P33527, Q16790, P49137, Q99720, P08842, Q01959, Q9Y5N1, P23219, O43570, P33261, P34972, P21554, P35348]	DRUG_AND_METABOLITE	0.485655263
N06AB04	citalopram	C0023530	leukopenia	1	[P08183]	DRUG	0.079913137
L02BB03	bicalutamide	C0006145	breast disorders	1	[P03372]	DRUG	0.014253709
M01AE09	flurbiprofen	C0025289	meningitis	1	[P10145]	DRUG	0.054359067
C10AA06	cerivastatin	C0024141	lupus	1	[Q92887]	DRUG_AND_METABOLITE	0.178744541
G02CB03	cabergoline	C0003123	anorexia	5	[P28223, P21917, P28335, P28221, P14416]	DRUG	1.48682E-06
M01AE01	ibuprofen	C0038454	cerebrovascular accident	3	[P28223, P35354, P27695]	METABOLITE	0.102854888
M01AE09	flurbiprofen	C0025290	aseptic meningitis	1	[P10145]	DRUG	0.042475697
L02BA01	tamoxifen	C0001418	adenocarcinoma	20	[P11509, P05181, P03372, P35354, P08183, P62508, Q92731, Q9UNQ0, P23219, P10275, Q16678, P17252, Q13393, P20815, P10632, P04798, P08684, P11511, P05177, P05771]	METABOLITE	1.54047E-05
C07AA03	pindolol	C0043144	wheezing	1	[P07550]	DRUG	0.301578738
N03AB02	phenytoin	C0001824	agranulocytosis	2	[Q92887, P08183]	DRUG	0.015024931
G04BE08	tadalafil	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.308196906
N06DA02	donepezil	C0003123	anorexia	2	[P28223, P21917]	DRUG	0.004163713
N05AB02	fluphenazine	C0001824	agranulocytosis	1	[P08183]	DRUG	0.087048961
N07BC02	methadone	C0042514	ventricular tachycardia	1	[P08588]	METABOLITE	0.057300091
N05BA12	alprazolam	C0002103	allergic rhinitis	1	[P11712]	DRUG	0.13798749
N07BC02	methadone	C0042109	urticaria	1	[P07550]	METABOLITE	0.104095707
N02AE01	buprenorphine	C0015672	fatigue	1	[P31645]	DRUG	0.037086334
S01AA14	penicillin G	C0018790	cardiac arrest	1	[Q14524]	DRUG	0.098169818
N05AX08	risperidone	C0020473	hyperlipidemia	1	[P07550]	DRUG_AND_METABOLITE	0.223959193
N06AX05	trazodone	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
M01AH03	valdecoxib	C0496899	benign brain neoplasm	2	[Q16790, P08842]	DRUG_AND_METABOLITE	0.097431078
G03AC06	medroxyprogesterone	C0010709	cyst	5	[P08183, P06401, P03372, P08235, P10275]	METABOLITE	0.019460121
N06AA09	amitriptyline	C0231218	malaise	1	[Q8NER1]	DRUG	0.049740783
L04AX02	thalidomide	C0024115	lung disorder	9	[P48506, P01375, P35354, P06239, Q08499, P27815, P05181, P04798, P05177]	DRUG	0.010413439
D01AE15	terbinafine	C0013395	Dyspepsia	1	[P23219]	DRUG	0.023338897
L04AX04	lenalidomide	C0036983	septic shock	1	[P01375]	DRUG	0.128824251
N06BA09	atomoxetine	C1269683	major depressive disorder	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.002528544
C07AG02	carvedilol	C0006384	bundle branch block	1	[Q14524]	DRUG	0.008782102
N06DX01	memantine	C0242422	Parkinson	1	[P22303]	DRUG	0.181991976
J01AA08	minocycline	C0011609	drug eruption	1	[P01584]	DRUG	0.030408848
L04AX04	lenalidomide	C0036974	shock	1	[P01375]	DRUG	0.051680751
N03AX09	lamotrigine	C0149931	migraine	1	[P35498]	DRUG	0.060203322
M01AE02	naproxen	C0038363	ulcerative stomatitis	1	[P31645]	DRUG	0.040204533
C01BD01	amiodarone	C0035078	renal failure	1	[P08183]	DRUG	0.10500023
N06AB03	fluoxetine	C0231218	malaise	1	[Q08499]	METABOLITE	0.029823411
L01BA01	methotrexate	C0038454	cerebrovascular accident	1	[P42898]	DRUG	0.229543829
A10BG02	rosiglitazone	C0020538	hypertension	4	[P37231, P11712, Q07869, P19793]	DRUG	0.007176695
N06AX06	nefazodone	C0003123	anorexia	6	[P28223, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.33344E-06
R03BA08	ciclesonide	C0019693	HIV infection	1	[P08684]	DRUG	0.063596471
N05AX08	risperidone	C0015672	fatigue	2	[P31645, P28223]	DRUG_AND_METABOLITE	0.009279632
N05AH02	clozapine	C0003123	anorexia	7	[P28223, P21917, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	3.16053E-06
M01AE02	naproxen	C0038358	gastric ulcer	2	[P35354, P23219]	DRUG	0.020334532
N06AX16	venlafaxine	C0021311	infection	3	[P07550, Q13936, P17252]	DRUG	0.482994146
N04BC05	pramipexole	C0031212	personality disorder	1	[P31645]	DRUG	0.031415297
N05AH02	clozapine	C0009951	convulsions	8	[P18507, Q9UBS5, P08183, P36544, P28472, P47870, P08908, P31645]	DRUG_AND_METABOLITE	0.000524472
N06AB05	paroxetine	C0011991	diarrhea	1	[P46098]	DRUG	0.060656663
A04AA01	ondansetron	C0151744	myocardial ischemia	3	[P07550, P08588, Q12809]	DRUG	0.014025764
N06AB05	paroxetine	C0023530	leukopenia	1	[P08183]	DRUG	0.09470362
H02AB02	dexamethasone	C0009951	convulsions	2	[P08183, P35354]	DRUG_AND_METABOLITE	0.094719012
C09AA04	perindopril	C0004096	asthma	1	[P12821]	DRUG_AND_METABOLITE	0.092356341
C09AA04	perindopril	C0004093	asthenia	1	[P12821]	DRUG_AND_METABOLITE	0.012425662
L01AA02	chlorambucil	C0015230	rash	1	[P14091]	DRUG	0.078558694
A10BG02	rosiglitazone	C0020456	hyperglycemia	1	[P37231]	DRUG_AND_METABOLITE	0.079263834
G03BA03	testosterone	C0023903	Hepatic neoplasms	15	[P08183, P02768, P04278, P03372, Q9UNQ0, Q06520, P31213, Q04828, Q14994, P20813, P28472, P10275, P08684, P05177, P05093]	DRUG_AND_METABOLITE	0.007486393
S01ED04	metipranolol	C0011603	dermatitis	2	[P07550, P08908]	METABOLITE	0.005743402
L01XX35	anagrelide	C0020538	hypertension	1	[P28223]	METABOLITE	0.202670332
G03AC06	medroxyprogesterone	C0243026	sepsis	1	[P04150]	DRUG_AND_METABOLITE	0.083525511
N06AA12	doxepin	C0003123	anorexia	9	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416, Q16620]	DRUG	1.48976E-07
C08CA05	nifedipine	C0242184	hypoxia	2	[P22460, Q12809]	DRUG	0.29064901
M01AH03	valdecoxib	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.113921026
C09AA01	captopril	C0039231	tachycardia	1	[P12821]	DRUG	0.028105805
N03AF01	carbamazepine	C1527304	allergic reaction	1	[P35367]	DRUG	0.088917357
G03CA03	estradiol	C0043144	wheezing	2	[O94956, P33527]	DRUG	0.407134574
M01AH01	celecoxib	C0010054	coronary artery disease	3	[P08684, P35354, P21554]	DRUG	0.119834131
N05AE04	ziprasidone	C0027059	myocarditis	2	[Q12809, P08588]	DRUG	0.095426205
L04AX02	thalidomide	C0004998	skin benign neoplasm	14	[P05177, P19838, P15104, P01375, P21802, P06239, P35354, P21980, P24298, P20815, P05181, P04798, P53985, P21554]	METABOLITE	0.46587329
L02BB03	bicalutamide	C0038454	cerebrovascular accident	1	[P03372]	DRUG	0.065144151
A07EA06	budesonide	C0020456	hyperglycemia	2	[P35354, P07148]	METABOLITE	0.028230054
C03CA04	torasemide	C0019080	hemorrhage	1	[P11712]	DRUG	0.031230552
M03BX08	cyclobenzaprine	C1456784	paranoia	1	[P05177]	DRUG_AND_METABOLITE	0.052795649
A02BC01	omeprazole	C0013390	dysmenorrhea	1	[P04798]	DRUG_AND_METABOLITE	0.021299045
C07AA07	sotalol	C0011570	mental depression	1	[P28222]	DRUG	0.051348531
L01BC06	capecitabine	C0011849	diabetes mellitus	3	[P11712, P02768, P10632]	METABOLITE	0.057524345
A07EC01	sulfasalazine	C0011991	diarrhea	1	[Q92887]	DRUG	0.054359067
N05BE01	buspirone	C0038454	cerebrovascular accident	2	[P28223, P07550]	DRUG_AND_METABOLITE	0.184452088
C10AA03	pravastatin	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.039009407
M01AE09	flurbiprofen	C0009319	colitis	3	[P10145, P35354, P12104]	DRUG	0.023270062
N05BA12	alprazolam	C0018799	heart disease	1	[P11712]	DRUG	0.289212683
J05AF01	zidovudine	C0015230	rash	1	[P28223]	METABOLITE	0.182806058
A10BG02	rosiglitazone	C0020433	bilirubinemia	1	[Q9Y6L6]	DRUG	0.040601904
C07AG02	carvedilol	C0021311	infection	5	[P07550, P15692, P19320, P47989, P23219]	DRUG	0.03201379
G03DA04	progesterone	C0013604	edema	1	[P08588]	METABOLITE	0.082202439
C03DA01	spironolactone	C0011991	diarrhea	1	[Q92887]	DRUG	0.039009407
N06AA02	imipramine	C0039070	syncope	1	[P29274]	METABOLITE	0.098727853
N06DA03	rivastigmine	C0031212	personality disorder	2	[P21397, P31645]	DRUG	6.31065E-05
M01AE01	ibuprofen	C0015230	rash	3	[P28223, P08908, P31645]	DRUG	0.117093195
N06AA06	trimipramine	C0013604	edema	1	[P08588]	DRUG_AND_METABOLITE	0.098727853
N06AA04	clomipramine	C0038363	ulcerative stomatitis	1	[P31645]	DRUG_AND_METABOLITE	0.059946991
L01AB01	busulfan	C0039730	thalassemia	1	[P08684]	DRUG	0.027162705
N06AB04	citalopram	C0149931	migraine	4	[P28223, P31645, P08684, P28335]	DRUG	8.41518E-05
P01BA01	chloroquine	C0023646	lichen planus	1	[P01375]	DRUG	0.028105805
N06AA04	clomipramine	C0038353	gastric dilatation	1	[P29475]	METABOLITE	0.039106452
N06AB03	fluoxetine	C0029445	bone necrosis	1	[P08183]	DRUG	0.091392995
N05AB04	prochlorperazine	C0026266	mitral insufficiency	2	[P31645, P23975]	DRUG_AND_METABOLITE	0.07602377
N06AB08	fluvoxamine	C0019158	hepatitis	1	[P05181]	DRUG_AND_METABOLITE	0.105026994
N06AB04	citalopram	C0023798	lipoma	5	[P05177, P08183, Q12809, P05181, P23975]	DRUG_AND_METABOLITE	0.23652563
N04BC05	pramipexole	C0006826	cancer	3	[Q9H3N8, Q9Y5N1, P23975]	DRUG	0.499995859
J01FA10	azithromycin	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.051619168
J01MA01	ofloxacin	C0019158	hepatitis	1	[P02768]	METABOLITE	0.091184812
N05AX12	aripiprazole	C0027051	myocardial infarction	5	[P21554, P07550, P31645, P08588, P18089]	DRUG_AND_METABOLITE	0.080521902
L01BA01	methotrexate	C0034065	pulmonary embolism	1	[P02768]	DRUG	0.046871884
G04BE09	vardenafil	C0027051	myocardial infarction	1	[Q08499]	DRUG	0.335953544
G03CA03	estradiol	C0004093	asthenia	1	[P08185]	DRUG_AND_METABOLITE	0.085892844
G03CA03	estradiol	C0004096	asthma	2	[O94956, P33527]	DRUG	0.407134574
N05AX08	risperidone	C0020517	hypersensitivity	5	[P41595, Q01959, P35367, P25021, Q9H3N8]	DRUG_AND_METABOLITE	0.000260019
N06AX21	duloxetine	C0019158	hepatitis	5	[P05181, P23219, P35354, P11509, P02768]	DRUG	0.003476378
L04AX01	azathioprine	C0001824	agranulocytosis	1	[P22309]	METABOLITE	0.115784639
N05AX08	risperidone	C0020538	hypertension	11	[P20815, P35348, P07550, P21728, P31645, Q9Y2I1, P28223, P23975, P08913, P18089, P08588]	DRUG_AND_METABOLITE	0.00012305
C02CA04	doxazosin	C0018801	heart failure	1	[Q12809]	DRUG	0.100095257
N06AB03	fluoxetine	C0029456	osteoporosis	2	[P08684, P10275]	METABOLITE	0.07797371
J01AA08	minocycline	C0021400	Influenza	2	[P42574, P29466]	DRUG	0.008887027
N06BA09	atomoxetine	C0152029	sinus congestion	3	[P25021, P35367, P08588]	DRUG	0.022311932
J02AC02	itraconazole	C0035078	renal failure	1	[P08183]	DRUG_AND_METABOLITE	0.060643265
S01AA14	penicillin G	C0018802	congestive heart failure	2	[Q16539, Q14524]	DRUG	0.056140305
N06DA03	rivastigmine	C0699790	colon cancer	1	[P22303]	DRUG_AND_METABOLITE	0.213042784
M01AH01	celecoxib	C0018799	heart disease	6	[P23219, P31645, P35354, P11712, P33527, P41595]	DRUG	0.012489538
N05AC02	thioridazine	C0018790	cardiac arrest	3	[Q12809, P18089, P07550]	DRUG	0.002948045
L04AX04	lenalidomide	C0007642	cellulitis	2	[Q07343, P01375]	DRUG	0.023929476
H02AB02	dexamethasone	C0020456	hyperglycemia	2	[P35354, P07148]	DRUG_AND_METABOLITE	0.030094767
M01AB02	sulindac	C0006266	bronchospasm	7	[P09917, Q13258, P35354, P23219, Q9Y5Y4, P37231, P27361]	DRUG	4.43967E-05
A10BX03	nateglinide	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.021600815
M01AB08	etodolac	C0038358	gastric ulcer	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.002078211
N04BC02	pergolide	C0013604	edema	1	[P08588]	DRUG	0.037128649
N05AB02	fluphenazine	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.012933575
N06AB04	citalopram	C0011603	dermatitis	3	[P28223, P08908, P31645]	DRUG	0.038042635
L02BG04	letrozole	C0155773	portal vein thrombosis	1	[P08684]	DRUG	0.059662382
N06AA10	nortriptyline	C0003123	anorexia	6	[P28223, P28335, P28221, P31645, P23975, P14416]	DRUG_AND_METABOLITE	1.54047E-05
A03FA01	metoclopramide	C0006266	bronchospasm	1	[P11229]	DRUG	0.33290977
M01AE03	ketoprofen	C0151827	eye pain	1	[P10145]	DRUG	0.035667691
L02BA01	tamoxifen	C0042133	uterine fibroids	6	[P03372, P11511, P04798, Q16678, P10275, Q92731]	DRUG_AND_METABOLITE	7.2241E-05
N05AB02	fluphenazine	C0686347	tardive dyskinesia	1	[P35498]	DRUG	0.054232974
N06BA09	atomoxetine	C0012833	dizziness	1	[P29274]	DRUG	0.032210774
J01AA02	doxycycline	C0699744	ear infection	4	[P04156, P08254, P08253, O14746]	DRUG	0.041952526
G04BE03	sildenafil	C0018790	cardiac arrest	1	[Q12809]	DRUG	0.075667737
G04BE03	sildenafil	C0018799	heart disease	2	[Q12809, P11712]	DRUG	0.149209487
C10AA05	atorvastatin	C0031117	peripheral neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.035667691
R06AE07	cetirizine	C0027430	nasal polyps	1	[Q12809]	DRUG	0.267761238
G04BE09	vardenafil	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.308196906
C09AA01	captopril	C0006266	bronchospasm	5	[P09211, P14780, P08253, P12821, P09960]	DRUG	0.002075365
L01XE03	erlotinib	C0009319	colitis	3	[P08183, Q9Y616, P20783]	DRUG_AND_METABOLITE	0.462497539
A02BA04	nizatidine	C0011991	diarrhea	1	[P46098]	DRUG	0.039009407
N02AA05	oxycodone	C0015230	rash	1	[P31645]	DRUG	0.107484566
G04BE03	sildenafil	C0014130	Endocrine Disorders	3	[Q12809, P04798, Q9HCR9]	DRUG	0.051449397
B05BC01	mannitol	C0042109	urticaria	1	[P12319]	METABOLITE	0.147384681
A07EA06	budesonide	C0020538	hypertension	8	[P20815, P35228, Q02928, P08235, P11511, P11712, P51843, P04150]	DRUG_AND_METABOLITE	0.000228904
R03AC02	salbutamol	C0024115	lung disorder	1	[P07550]	DRUG	0.080482871
C03CA01	furosemide	C0011849	diabetes mellitus	3	[O15245, P28845, P02768]	DRUG	0.057524345
L01BA01	methotrexate	C0009951	convulsions	3	[P08183, P42898, P33527]	DRUG	0.024401265
N04BC02	pergolide	C0013595	eczema	3	[P07550, P28223, P08908]	DRUG_AND_METABOLITE	0.018896001
N03AX09	lamotrigine	C0039231	tachycardia	1	[Q14524]	DRUG	0.022511552
N07XX02	riluzole	C0018524	hallucinations	2	[Q99250, O00555]	DRUG	0.011432473
A10BB09	gliclazide	C0001339	acute pancreatitis	1	[P15692]	DRUG	0.051696381
N02AA01	morphine	C0006266	bronchospasm	1	[P23219]	DRUG	0.369658864
C10AA04	fluvastatin	C0003123	anorexia	1	[P27487]	DRUG_AND_METABOLITE	0.059045073
C07AB07	bisoprolol	C0006266	bronchospasm	1	[P07550]	DRUG_AND_METABOLITE	0.105539171
C10AA03	pravastatin	C0023890	cirrhosis	1	[P08684]	DRUG_AND_METABOLITE	0.165002898
M01AG01	mefenamic acid	C0020538	hypertension	2	[P08235, P11712]	DRUG	0.044396476
G04BE03	sildenafil	C0018801	heart failure	1	[Q12809]	DRUG	0.14275329
V03AF03	leucovorin	C0023530	leukopenia	1	[Q92887]	DRUG_AND_METABOLITE	0.044087091
C08CA02	felodipine	C0041912	upper respiratory tract infection	3	[P03372, Q13936, Q16548]	METABOLITE	0.228923227
C07AG02	carvedilol	C0152029	sinus congestion	1	[P08588]	DRUG_AND_METABOLITE	0.119015812
M01AE02	naproxen	C0009951	convulsions	5	[P33527, P08908, P31645, P35354, P49768]	DRUG	0.009521978
L01XE02	gefitinib	C1527304	allergic reaction	1	[O60674]	DRUG_AND_METABOLITE	0.366836091
N05AD01	haloperidol	C0242422	Parkinson	10	[P21917, P05181, Q01959, P08183, P50406, P08908, P31645, Q9UQD0, P14416, P35462]	DRUG_AND_METABOLITE	7.89828E-05
N02AA01	morphine	C0011206	delirium	1	[P21554]	METABOLITE	0.049355201
N07XX02	riluzole	C0014130	Endocrine Disorders	1	[P04798]	DRUG	0.184948224
M01AH02	rofecoxib	C0019348	herpes simplex	2	[P03973, P43116]	DRUG_AND_METABOLITE	0.045839725
M01AG01	mefenamic acid	C0020456	hyperglycemia	1	[P35354]	DRUG	0.054232974
R06AB04	chlorpheniramine	C0015672	fatigue	2	[P31645, P28223]	DRUG	0.002877124
R03AC02	salbutamol	C0149931	migraine	1	[P08684]	DRUG	0.026766868
N02AA05	oxycodone	C0027651	tumor	4	[P08684, Q99720, P20815, P23975]	DRUG	0.280349021
C10AA06	cerivastatin	C0020538	hypertension	2	[P20815, P11712]	DRUG_AND_METABOLITE	0.06570642
N05AE04	ziprasidone	C0011615	atopic dermatitis	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG	0.003689443
A08AB01	orlistat	C1527304	allergic reaction	1	[Q13093]	DRUG	0.048595777
J05AB04	ribavirin	C0019196	Hepatitis C	1	[P22413]	DRUG	0.102909805
M01AB08	etodolac	C0002871	anemia	1	[P02768]	DRUG	0.064439777
M01AC01	piroxicam	C0017152	gastritis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.00233581
N03AF01	carbamazepine	C0032285	pneumonia	1	[P35354]	METABOLITE	0.128451012
C02CA01	prazosin	C0004093	asthenia	1	[P28223]	DRUG_AND_METABOLITE	0.056501401
C01BD01	amiodarone	C0023211	left bundle branch block	1	[Q14524]	DRUG	0.009287022
L04AX02	thalidomide	C0014549	grand mal	1	[P43003]	METABOLITE	0.17722786
C07AB07	bisoprolol	C0018802	congestive heart failure	1	[P07550]	DRUG_AND_METABOLITE	0.040601904
C07AB07	bisoprolol	C0018801	heart failure	1	[P07550]	DRUG_AND_METABOLITE	0.040601904
N05CF02	zolpidem	C0020538	hypertension	2	[P20815, P11712]	DRUG	0.127687099
N03AF02	oxcarbazepine	C0149931	migraine	2	[P35498, P08684]	DRUG	0.002812013
N05AX08	risperidone	C0015230	rash	6	[P07550, P21731, P28223, P08908, P31645, Q9Y271]	DRUG_AND_METABOLITE	0.00348143
J01DC04	cefaclor	C0019158	hepatitis	1	[P02768]	DRUG	0.060203322
A08AA10	sibutramine	C0009951	convulsions	2	[P08908, P31645]	DRUG_AND_METABOLITE	0.045203907
D06BB10	imiquimod	C0007097	carcinoma	2	[P08684, P05177]	DRUG	0.156192971
A16AA04	cysteamine	C0085584	encephalopathy	2	[P14867, P35372]	DRUG_AND_METABOLITE	0.073427972
N02BA11	diflunisal	C0027726	nephrotic syndrome	2	[P35354, P02768]	DRUG	0.039477339
G03CA03	estradiol	C0027813	neuritis	1	[P08183]	DRUG_AND_METABOLITE	0.163956105
N06AB05	paroxetine	C0011849	diabetes mellitus	3	[P11712, P18089, P10632]	DRUG	0.089551563
C07AB07	bisoprolol	C0018790	cardiac arrest	1	[P07550]	DRUG_AND_METABOLITE	0.021841092
C07AA12	nadolol	C0001824	agranulocytosis	1	[P08183]	DRUG	0.022511552
N05AH02	clozapine	C0015230	rash	5	[P07550, P21731, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.026413764
N07BA03	varenicline	C0010709	cyst	2	[P11230, P36544]	DRUG	0.257746653
C03CA01	furosemide	C0011991	diarrhea	1	[Q92887]	DRUG	0.051010927
N07AX01	pilocarpine	C0030305	pancreatitis	1	[P05181]	DRUG	0.069985391
C07AG02	carvedilol	C0006266	bronchospasm	5	[P07550, P15692, P47989, P19320, P23219]	DRUG	0.003335247
A10BB03	tolbutamide	C0162566	porphyria cutanea tarda	1	[P05177]	DRUG	0.023643559
C07AG02	carvedilol	C0006277	bronchitis	1	[P15692]	DRUG	0.030408848
M01AE02	naproxen	C0004096	asthma	5	[P09917, P08246, P35354, P23219, P33527]	DRUG	0.058255985
M01AE02	naproxen	C0004093	asthenia	3	[P31645, P28223, P35354]	DRUG	0.000516726
C09CA07	telmisartan	C0020443	hypercholesterolemia	1	[P30556]	DRUG	0.052994355
N07XX02	riluzole	C0018681	headache	1	[O00555]	DRUG	0.03490134
N05AE04	ziprasidone	C0039231	tachycardia	2	[P07550, P08588]	DRUG	0.005396749
N06AA02	imipramine	C0039231	tachycardia	2	[P07550, P08588]	DRUG_AND_METABOLITE	0.014245386
G03XC01	raloxifene	C0029925	ovarian cancer	5	[P11511, P08684, P03372, Q92731, P10632]	DRUG	0.006002348
L04AX04	lenalidomide	C0085669	acute leukemia	5	[P19838, P20815, P04798, P01375, P05177]	DRUG	0.014765162
M01AB05	diclofenac	C0041582	ulcer	1	[P10145]	DRUG_AND_METABOLITE	0.07797371
C07AG02	carvedilol	C0428977	bradycardia	1	[Q14524]	DRUG	0.018096702
N03AX09	lamotrigine	C0009951	convulsions	4	[P35498, P08183, Q99250, Q9NY46]	DRUG	0.000488431
J01FA10	azithromycin	C0004096	asthma	2	[P00813, P33527]	DRUG_AND_METABOLITE	0.092998912
N06AA04	clomipramine	C0040822	tremor	1	[Q14643]	METABOLITE	0.069361242
C08CA04	nicardipine	C0039070	syncope	1	[P29274]	DRUG	0.042974428
N04BC05	pramipexole	C0006325	bruxism	1	[P31645]	DRUG	0.020240076
J01AA02	doxycycline	C0020538	hypertension	2	[P08254, P08253]	DRUG	0.099373048
N01BA02	procaine	C0428977	bradycardia	1	[Q14524]	DRUG	0.030205472
G04CA03	terazosin	C0022408	arthrosis	1	[Q9H3N8]	METABOLITE	0.219123965
M01AG01	mefenamic acid	C0018802	congestive heart failure	1	[P08235]	METABOLITE	0.062319473
A03FA01	metoclopramide	C0013604	edema	1	[P08588]	DRUG	0.037934867
J05AF03	zalcitabine	C0015230	rash	2	[P26358, P81605]	METABOLITE	0.077843187
N06DA02	donepezil	C0014394	enuresis	2	[P28223, P21917]	DRUG	0.000875659
A02BC02	pantoprazole	C0152029	sinus congestion	1	[P25021]	METABOLITE	0.128454628
N06AB04	citalopram	C0039231	tachycardia	1	[P08588]	DRUG	0.033737522
N06AB04	citalopram	C0011849	diabetes mellitus	2	[O15245, P08684]	DRUG	0.143731103
C09CA01	losartan	C0034063	pulmonary edema	1	[P12821]	DRUG	0.025953097
M01AG01	mefenamic acid	C0018834	heartburn	1	[P23219]	DRUG	0.017783546
J05AE01	saquinavir	C0022346	jaundice	1	[Q9Y6L6]	DRUG	0.023218364
N05CF02	zolpidem	C0020473	hyperlipidemia	1	[P23219]	DRUG	0.114516617
J02AC01	fluconazole	C0015230	rash	1	[P09601]	DRUG	0.114580337
G04CA02	tamsulosin	C0020517	hypersensitivity	2	[P19801, P35367]	DRUG	0.016226908
R03DC03	montelukast	C0021311	infection	2	[P23219, P09917]	DRUG_AND_METABOLITE	0.09470362
M01AE09	flurbiprofen	C0013395	Dyspepsia	1	[P23219]	DRUG_AND_METABOLITE	0.034424934
J01FA09	clarithromycin	C0010709	cyst	6	[P25025, P05177, P08183, Q12809, P33527, P20815]	DRUG_AND_METABOLITE	0.040353299
M01AH03	valdecoxib	C0019158	hepatitis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.054555669
L01XE01	imatinib	C0007784	cerebral hemorrhage	2	[P24723, O60674]	DRUG	0.488021852
C08DB01	diltiazem	C0035078	renal failure	1	[P08183]	DRUG	0.11475139
N06AB05	paroxetine	C0011579	depressive reaction	4	[P28223, P28335, P28222, P23975]	DRUG_AND_METABOLITE	4.44203E-05
C03CA02	bumetanide	C0740394	hyperuricemia	1	[Q9NSA0]	DRUG	0.034852775
C09AA02	enalapril	C0027947	neutropenia	1	[P08183]	DRUG	0.037092814
N02AA03	hydromorphone	C0011991	diarrhea	1	[O60656]	DRUG	0.060656663
J02AC02	itraconazole	C0023895	liver disease	2	[P21439, P08684]	DRUG_AND_METABOLITE	0.014253709
J05AF01	zidovudine	C0019158	hepatitis	2	[P11509, P02768]	DRUG	0.018096702
N04BC05	pramipexole	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG	0.013731895
J02AC02	itraconazole	C0023890	cirrhosis	3	[P21439, P08684, P05181]	DRUG_AND_METABOLITE	0.002232681
N06AB06	sertraline	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.054232974
C10AB05	fenofibrate	C0030920	peptic ulcer	1	[P37231]	DRUG_AND_METABOLITE	0.050501715
N06AX21	duloxetine	C0030196	Pain in limb	1	[Q8NER1]	DRUG	0.04687583
L04AX02	thalidomide	C0020757	ichthyosis	4	[P22735, O43548, Q07343, P01375]	DRUG	0.041156839
C09AA07	benazepril	C0004096	asthma	2	[P12821, P42898]	DRUG	0.013492314
C09AA07	benazepril	C0004093	asthenia	1	[P12821]	DRUG_AND_METABOLITE	0.012425662
C07AA07	sotalol	C0015230	rash	1	[P07550]	DRUG	0.114580337
M03BX08	cyclobenzaprine	C0019158	hepatitis	3	[P05181, P23219, P02768]	DRUG_AND_METABOLITE	0.038508848
S01EA05	brimonidine	C0020538	hypertension	3	[P35348, P08913, P18089]	DRUG_AND_METABOLITE	0.0055472
N03AX09	lamotrigine	C0009806	constipation	1	[Q14524]	DRUG	0.024401265
G03DA04	progesterone	C0039231	tachycardia	1	[P08588]	METABOLITE	0.075413212
A01AC01	triamcinolone	C0004093	asthenia	2	[P08185, P04150]	DRUG	6.65688E-05
N07XX02	riluzole	C0018790	cardiac arrest	1	[Q14524]	DRUG	0.045033357
N07XX02	riluzole	C0018799	heart disease	1	[Q14524]	DRUG	0.199197698
N02AE01	buprenorphine	C0015230	rash	1	[P31645]	DRUG	0.188454274
L02BB02	nilutamide	C0020538	hypertension	1	[P11712]	DRUG	0.106277208
C09CA01	losartan	C0026821	muscle cramps	1	[Q08499]	DRUG	0.022436068
C08DB01	diltiazem	C0152029	sinus congestion	1	[P35367]	DRUG	0.138184403
N05AH03	olanzapine	C0026650	movement disorders	3	[P14416, P21917, P35462]	DRUG	0.004393943
N06AB08	fluvoxamine	C0001818	agoraphobia	2	[P23975, P31645]	DRUG_AND_METABOLITE	0.000111104
N06AX21	duloxetine	C0015695	liver fatty	2	[P02768, P05181]	DRUG	0.083292037
M01AH03	valdecoxib	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.12771719
H02AB02	dexamethasone	C0020538	hypertension	8	[P20815, P35228, Q02928, P08235, P11511, P11712, P51843, P04150]	DRUG_AND_METABOLITE	0.0003046
C09CA04	irbesartan	C0007787	transient ischemic attack	1	[P30556]	DRUG_AND_METABOLITE	0.049485821
A02BC01	omeprazole	C0442874	neuropathy	1	[P08183]	DRUG_AND_METABOLITE	0.12507432
N07XX02	riluzole	C0002874	aplastic anemia	1	[P04798]	DRUG	0.09412399
N06AB08	fluvoxamine	C0001824	agranulocytosis	1	[P08183]	DRUG_AND_METABOLITE	0.059748572
L01XX11	estramustine	C0027051	myocardial infarction	10	[P02768, P03372, P04798, P10275, P04278, Q92731, P11712, P33261, P05177, Q12791]	METABOLITE	6.31065E-05
N06BA04	methylphenidate	C0031212	personality disorder	1	[P31645]	DRUG_AND_METABOLITE	0.029637746
N04BX01	tolcapone	C0003123	anorexia	2	[P21964, P27487]	METABOLITE	0.004738942
M04AA01	allopurinol	C0006266	bronchospasm	7	[P00533, P16220, P00813, P47989, P29274, Q08499, P12931]	METABOLITE	0.036564399
C01CA24	epinephrine	C0019080	hemorrhage	1	[P11712]	DRUG	0.088782147
M01AH02	rofecoxib	C0019158	hepatitis	2	[P23219, P35354]	DRUG_AND_METABOLITE	0.050365655
N07XX02	riluzole	C0018801	heart failure	1	[Q14524]	DRUG	0.08498899
N07XX02	riluzole	C0018802	congestive heart failure	1	[Q14524]	DRUG	0.08498899
J05AE01	saquinavir	C0019080	hemorrhage	1	[P11712]	DRUG	0.069716619
A02BC02	pantoprazole	C0019080	hemorrhage	1	[P11712]	DRUG_AND_METABOLITE	0.07985866
N02AA01	morphine	C0575081	abnormal gait	1	[P35498]	DRUG_AND_METABOLITE	0.049355201
N06AX06	nefazodone	C0038454	cerebrovascular accident	2	[P28223, P07550]	METABOLITE	0.105539171
N03AX09	lamotrigine	C0027051	myocardial infarction	2	[P11712, P33261]	DRUG	0.085289777
R06AX17	ketotifen	C0021311	infection	2	[P78527, P09917]	DRUG	0.344347567
P01BC02	mefloquine	C0020538	hypertension	1	[P11511]	DRUG	0.18054561
M01AE12	oxaprozin	C0030305	pancreatitis	1	[P35354]	DRUG	0.057999431
A03BA01	atropine	C0020456	hyperglycemia	1	[Q9Y210]	DRUG_AND_METABOLITE	0.105876857
G04CA03	terazosin	C0038454	cerebrovascular accident	1	[P28223]	DRUG_AND_METABOLITE	0.277558428
N06AX16	venlafaxine	C0037763	spasm	1	[P14867]	DRUG	0.090619814
A10BB09	gliclazide	C0010054	coronary artery disease	2	[P02768, P15692]	DRUG	0.012489538
A07EC01	sulfasalazine	C0009951	convulsions	1	[P35354]	DRUG_AND_METABOLITE	0.218571686
L04AX04	lenalidomide	C0003123	anorexia	1	[P01375]	DRUG	0.071241753
N06AX06	nefazodone	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.014374872
C08DA01	verapamil	C0022346	jaundice	1	[Q9Y6L6]	DRUG	0.042510997
C10AA07	rosuvastatin	C0002994	angioedema	1	[P27487]	DRUG	0.004163713
C10AA02	lovastatin	C0006826	cancer	34	[P08183, P04818, P49327, P42330, Q12882, P05362, Q96EB6, P05093, P20815, P05181, P10632, P15428, P08684, P09601, P07858, Q92769, Q13363, P09874, P00338, P00352, P00325, P04406, P37059, P80365, P53985, P05091, P29475, P00390, O95169, P40394, P00326, P14550, P03923, P47989]	METABOLITE	0.499995859
A07EC01	sulfasalazine	C0011570	mental depression	1	[P08684]	METABOLITE	0.099106167
M01AE02	naproxen	C0162566	porphyria cutanea tarda	1	[P05177]	DRUG	0.051415029
C09AA03	lisinopril	C0013404	dyspnea	1	[P12821]	DRUG	0.017596968
N06AA02	imipramine	C0027051	myocardial infarction	14	[P02768, P21554, P13945, P05362, P06276, P07550, P11712, P33261, P31645, P23219, P05177, P08588, P18089, Q12791]	METABOLITE	0.002889839
C09AA10	trandolapril	C0041912	upper respiratory tract infection	1	[Q9BYF1]	DRUG	0.14501301
M04AA01	allopurinol	C0019080	hemorrhage	1	[P00813]	METABOLITE	0.177307674
H02AB07	prednisone	C0030920	peptic ulcer	1	[P33261]	METABOLITE	0.082956716
L01AB01	busulfan	C0006826	cancer	5	[P08684, P08263, P00325, P40394, P00326]	METABOLITE	0.04589144
N06AB05	paroxetine	C0007820	cerebrovascular disorder	1	[P28223]	DRUG	0.277558428
N02CC06	eletriptan	C0497327	dementia	1	[P08908]	DRUG	0.150445774
N05CA01	pentobarbital	C0004134	ataxia	1	[P35498]	DRUG	0.12372407
M01AE02	naproxen	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG	0.000289461
C10AA03	pravastatin	C0023530	leukopenia	2	[Q92887, P08183]	DRUG_AND_METABOLITE	0.007713391
N06AX16	venlafaxine	C0000768	malformations	1	[P17252]	DRUG	0.186069792
M01AX01	nabumetone	C0015230	rash	1	[P07711]	METABOLITE	0.086440059
G04BE03	sildenafil	C0010054	coronary artery disease	3	[P08684, Q08499, P04798]	DRUG	0.05226618
J05AE01	saquinavir	C0019158	hepatitis	1	[P02768]	DRUG	0.099373048
A07DA03	loperamide	C0009806	constipation	1	[P31645]	METABOLITE	0.034147949
A04AA01	ondansetron	C1527304	allergic reaction	2	[P41595, P35367]	DRUG	0.041305035
N06AB03	fluoxetine	C0042024	urinary incontinence	3	[P08172, P28223, P21917]	DRUG	0.000622281
B01AC04	clopidogrel	C0018944	hematoma	1	[P11712]	DRUG	0.03490134
J05AE03	ritonavir	C0009324	ulcerative colitis	1	[P08183]	DRUG	0.170666191
J05AE03	ritonavir	C0009319	colitis	1	[P08183]	DRUG	0.178859906
N05BE01	buspirone	C0878544	cardiomyopathy	2	[Q12809, P08588]	DRUG_AND_METABOLITE	0.10311102
C09CA01	losartan	C0030319	panic disorder	3	[P33261, P08684, P05177]	DRUG	0.00054791
N03AF01	carbamazepine	C0011991	diarrhea	1	[P46098]	DRUG	0.054359067
R03AC13	formoterol	C0020538	hypertension	4	[P13945, P07550, P11712, P08588]	DRUG	0.000301591
R06AX02	cyproheptadine	C0013604	edema	1	[P08588]	DRUG	0.063596471
N01BB01	bupivacaine	C0442874	neuropathy	2	[Q9UQD0, P08183]	METABOLITE	0.0339924
L01CB01	etoposide	C0021311	infection	2	[P11387, P42574]	DRUG_AND_METABOLITE	0.245556276
M01AX01	nabumetone	C0027051	myocardial infarction	2	[P35354, P23219]	DRUG_AND_METABOLITE	0.034440795
D07AC18	prednicarbate	C0021311	infection	2	[P03372, P04150]	DRUG_AND_METABOLITE	0.288907873
N06DA02	donepezil	C0019080	hemorrhage	1	[P11712]	DRUG	0.047592614
N05AE04	ziprasidone	C0039520	tenosynovitis	1	[P35408]	DRUG	0.052883334
N06BA07	modafinil	C0018621	seasonal allergic rhinitis	1	[Q01959]	DRUG	0.060597648
M01AB05	diclofenac	C0018524	hallucinations	2	[P08183, P33527]	DRUG	0.058500766
A03BA01	atropine	C0020517	hypersensitivity	1	[P35367]	DRUG_AND_METABOLITE	0.103034195
M01AE03	ketoprofen	C0021311	infection	3	[P10145, P35354, P23219]	DRUG	0.09498999
C01BD01	amiodarone	C0030305	pancreatitis	1	[P04798]	DRUG	0.149633234
L04AA13	leflunomide	C0010709	cyst	6	[P05177, P03956, P10275, Q14289, P35869, P09917]	DRUG	0.016701405
B01AC05	ticlopidine	C0042384	vasculitis	1	[P05164]	DRUG_AND_METABOLITE	0.060396293
N03AX16	pregabalin	C0018681	headache	1	[O00555]	DRUG	0.024082184
L01XE01	imatinib	C0520474	osteonecrosis	1	[P08183]	DRUG	0.295862803
N02AX02	tramadol	C0037315	sleep apnea	1	[P31645]	DRUG_AND_METABOLITE	0.015405718
C07AA05	propranolol	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG	0.010781267
J01MA02	ciprofloxacin	C0027051	myocardial infarction	1	[P05177]	DRUG	0.244972902
A04AA01	ondansetron	C0015230	rash	3	[P07550, P28223, P08908]	DRUG	0.097925036
N05AH03	olanzapine	C0018524	hallucinations	1	[P36544]	DRUG	0.201694851
N03AB02	phenytoin	C0034065	pulmonary embolism	1	[P02768]	DRUG	0.056501401
L04AX02	thalidomide	C0020538	hypertension	8	[P20815, Q08499, P35348, P21728, P48506, P11712, P01375, Q07075]	METABOLITE	0.04766001
C07AA06	timolol	C0011570	mental depression	3	[P33261, P28223, P08908]	DRUG	0.000200874
H02AB06	prednisolone	C0034063	pulmonary edema	1	[P19099]	DRUG_AND_METABOLITE	0.025953097
N03AB02	phenytoin	C0013384	dyskinesia	1	[P35498]	DRUG_AND_METABOLITE	0.132566149
L04AA13	leflunomide	C0009319	colitis	2	[P03956, Q9UM07]	DRUG	0.030238297
N06BA01	amphetamine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000810085
J01AA08	minocycline	C0015230	rash	6	[P14780, P08254, P08253, P01584, P42574, P15692]	DRUG	3.57657E-05
N05AE04	ziprasidone	C0085649	peripheral edema	1	[P08588]	DRUG	0.063186267
N02CC01	sumatriptan	C0013604	edema	1	[P08588]	DRUG	0.05226618
C10AA02	lovastatin	C0022346	jaundice	2	[Q9Y6L6, P11413]	METABOLITE	0.018639754
R03BA08	ciclesonide	C0011849	diabetes mellitus	1	[P08684]	DRUG	0.105539171
N06AA11	protriptyline	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.02477419
N02AA05	oxycodone	C0015672	fatigue	1	[P31645]	DRUG	0.021841092
C07AA03	pindolol	C0006266	bronchospasm	1	[P07550]	DRUG	0.301578738
N06AB03	fluoxetine	C0042133	uterine fibroids	2	[P10275, Q12809]	DRUG	0.091184812
C08CA06	nimodipine	C0043144	wheezing	1	[P29274]	DRUG	0.229748353
N01AH01	fentanyl	C0242422	Parkinson	3	[P08183, P27338, P14416]	DRUG	0.010207101
A03FA01	metoclopramide	C0013384	dyskinesia	2	[P14416, P35462]	DRUG	0.018565461
N06AB05	paroxetine	C0039231	tachycardia	1	[P08588]	DRUG	0.03976834
G04CA02	tamsulosin	C0013395	Dyspepsia	1	[P23219]	METABOLITE	0.031289625
G03DA04	progesterone	C0034065	pulmonary embolism	1	[P02768]	METABOLITE	0.094013826
N06AX05	trazodone	C0011991	diarrhea	2	[P46098, A5X5Y0]	METABOLITE	0.014515887
N04BC02	pergolide	C0085649	peripheral edema	1	[P08588]	DRUG	0.037128649
R03AC13	formoterol	C0020473	hyperlipidemia	1	[P07550]	DRUG	0.051022002
N06AX11	mirtazapine	C0009319	colitis	3	[P31645, A5X5Y0, P46098]	DRUG_AND_METABOLITE	0.035459478
J02AC02	itraconazole	C0027947	neutropenia	1	[P08183]	DRUG_AND_METABOLITE	0.037092814
C09AA10	trandolapril	C0004604	back pain	1	[P12821]	DRUG_AND_METABOLITE	0.002297402
S01JA01	fluorescein	C0009951	convulsions	1	[P33527]	DRUG	0.108919575
A10BB09	gliclazide	C0010692	cystitis	1	[P15692]	DRUG	0.022511552
L01XE01	imatinib	C0019080	hemorrhage	1	[P11712]	DRUG	0.378216014
C01EB03	indomethacin	C0042384	vasculitis	1	[Q96J66]	DRUG	0.09505443
N03AF02	oxcarbazepine	C0428977	bradycardia	1	[Q14524]	DRUG	0.009521978
M01AH01	celecoxib	C0010709	cyst	8	[O43570, Q16539, P35354, P33527, Q16790, P23975, P18054, P09917]	DRUG	0.392397671
M01AE02	naproxen	C0011168	dysphagia	1	[P49768]	DRUG	0.080521902
A07EC04	balsalazide	C0151798	hepatic necrosis	1	[P37231]	DRUG_AND_METABOLITE	0.099257725
L01XE01	imatinib	C0021311	infection	29	[P42336, P00533, P23458, P00519, Q9UBN7, Q13546, P19525, P08631, Q02156, P43405, P78362, Q96SB4, P04049, P52799, P16234, Q13153, P23219, P04629, P49771, P31749, P17252, Q14164, P28482, O43353, Q16539, P27361, Q04759, P36897, P37173]	DRUG	0.089658424
R01AD01	beclomethasone	C0030193	pain	1	[P11511]	DRUG_AND_METABOLITE	0.03976834
N06AB04	citalopram	C0011991	diarrhea	1	[P46098]	DRUG	0.051010927
N04BX01	tolcapone	C0007097	carcinoma	3	[P27487, P21964, P06493]	METABOLITE	0.345517289
L04AA06	mycophenolic acid	C0004998	skin benign neoplasm	2	[P22309, P37231]	DRUG_AND_METABOLITE	0.116012523
N02CC01	sumatriptan	C0013595	eczema	3	[P07550, P28223, P08908]	DRUG	0.047522675
A02BC01	omeprazole	C0699744	ear infection	1	[P08575]	DRUG_AND_METABOLITE	0.452861437
N03AX16	pregabalin	C0018790	cardiac arrest	1	[P54289]	DRUG	0.031878908
C01BB02	mexiletine	C0019158	hepatitis	1	[P05181]	DRUG	0.222747961
L04AX02	thalidomide	C0020676	hypothyroidism	1	[P01375]	DRUG	0.207982133
C09AA08	cilazapril	C0036421	scleroderma	1	[P12821]	DRUG	0.045839725
H02AB07	prednisone	C0018802	congestive heart failure	1	[P08235]	DRUG_AND_METABOLITE	0.114588485
N06AB03	fluoxetine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.000182901
G04BE03	sildenafil	C0878544	cardiomyopathy	3	[O76074, O15440, Q12809]	DRUG	0.010538298
C09AA03	lisinopril	C0004604	back pain	1	[P12821]	DRUG	0.002297402
C09CA06	candesartan	C0027121	myositis	1	[P23219]	DRUG_AND_METABOLITE	0.048595777
N02CC01	sumatriptan	C1458155	breast neoplasm	14	[Q9UNQ0, P04798, Q16678, P08684, P03372, P08183, Q92731, P14061, P46721, P05181, P05177, P10275, P20813, P20815]	METABOLITE	0.214992619
L04AX02	thalidomide	C0020615	hypoglycemia	2	[P48506, P53985]	METABOLITE	0.06217145
N02AA03	hydromorphone	C0011849	diabetes mellitus	4	[P11712, O15245, P08684, P10632]	DRUG_AND_METABOLITE	0.03763883
C09AA08	cilazapril	C0023530	leukopenia	1	[P08183]	DRUG	0.023338897
L01XE01	imatinib	C0019158	hepatitis	2	[P23219, P02768]	DRUG	0.344712038
M01AE12	oxaprozin	C0030920	peptic ulcer	2	[P35354, P23219]	DRUG	0.00133157
C10AA02	lovastatin	C0231528	myalgia	4	[Q9Y6L6, P16219, P29475, P05362]	DRUG	0.065109615
C03DB01	amiloride	C0032285	pneumonia	3	[Q16853, P00750, P00749]	DRUG	0.011039506
G03CA03	estradiol	C0020565	breast enlargement	1	[P03372]	DRUG_AND_METABOLITE	0.226344843
N05BE01	buspirone	C0042109	urticaria	1	[P07550]	DRUG_AND_METABOLITE	0.110876596
J01FA09	clarithromycin	C0018799	heart disease	2	[Q12809, P33527]	DRUG	0.06351216
M03BX01	baclofen	C0036572	seizures	2	[Q99250, P35498]	DRUG	0.005625009
M01AB05	diclofenac	C0018799	heart disease	7	[P10145, P23219, P35354, P11712, P20813, P33527, P41595]	DRUG	0.004163713
A08AA10	sibutramine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	2.12129E-05
C10AA05	atorvastatin	C0009319	colitis	1	[P08183]	DRUG_AND_METABOLITE	0.166846606
H02AB02	dexamethasone	C0033975	psychosis	2	[P47712, P04150]	DRUG_AND_METABOLITE	0.035833772
N05AE04	ziprasidone	C0011991	diarrhea	2	[P46098, A5X5Y0]	DRUG	0.014891624
L04AX02	thalidomide	C0010709	cyst	13	[P05177, P19838, P15104, P01375, P21802, P06239, P35354, P21980, P24298, P20815, P05181, P04798, P53985]	METABOLITE	0.48000269
N06AA17	amoxapine	C0011991	diarrhea	1	[P46098]	DRUG_AND_METABOLITE	0.077261871
J05AE01	saquinavir	C0019360	herpes zoster	1	[P05108]	DRUG	0.026275405
N04BB01	amantadine	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.097706703
L04AX02	thalidomide	C0004134	ataxia	3	[P80404, P43003, Q99259]	METABOLITE	0.026969664
N06AA09	amitriptyline	C0686347	tardive dyskinesia	1	[P35498]	DRUG_AND_METABOLITE	0.105805072
C09CA07	telmisartan	C0023895	liver disease	4	[Q92887, P37231, Q96RI1, Q03181]	DRUG	0.000115895
N06AB03	fluoxetine	C0151825	bone pain	1	[Q08499]	METABOLITE	0.029823411
N06AB03	fluoxetine	C0151827	eye pain	1	[Q08499]	METABOLITE	0.070407486
C09XA02	aliskiren	C0013604	edema	1	[P00797]	DRUG_AND_METABOLITE	0.013961737
L04AX04	lenalidomide	C0007859	neck pain	1	[Q08499]	DRUG	0.019239124
C10AB05	fenofibrate	C0010054	coronary artery disease	3	[P37231, P08684, Q07869]	DRUG_AND_METABOLITE	0.007278392
L01XE01	imatinib	C0021400	Influenza	1	[P60953]	DRUG	0.366172041
L04AX04	lenalidomide	C0018799	heart disease	5	[O14788, P23219, P35354, P01375, P11712]	DRUG	0.000786393
C07AG02	carvedilol	C0038454	cerebrovascular accident	3	[P16860, P19320, P07550]	DRUG_AND_METABOLITE	0.012947467
R03AC02	salbutamol	C0151744	myocardial ischemia	2	[P07550, P08588]	DRUG	0.000856501
J05AF04	stavudine	C0015695	liver fatty	1	[P02768]	METABOLITE	0.096593322
L02BA01	tamoxifen	C0013395	Dyspepsia	1	[P23219]	DRUG	0.042381513
N06BA07	modafinil	C0018799	heart disease	2	[P11712, P20813]	DRUG	0.042475697
C09CA01	losartan	C0030193	pain	1	[Q08499]	DRUG	0.03201379
N05AH03	olanzapine	C0018790	cardiac arrest	3	[Q12809, P18089, P07550]	DRUG_AND_METABOLITE	0.002697338
N06AB03	fluoxetine	C0009951	convulsions	3	[P08183, P08908, P31645]	DRUG_AND_METABOLITE	0.051696381
M01AG01	mefenamic acid	C0032285	pneumonia	1	[P35354]	DRUG	0.062319473
L04AX02	thalidomide	C0036572	seizures	1	[P43003]	METABOLITE	0.166282449
N05AH03	olanzapine	C0349231	phobia	1	[P31645]	DRUG	0.017306495
N07BB04	naltrexone	C0009319	colitis	2	[P08183, P31645]	DRUG	0.030238297
C01BB01	lidocaine	C0021311	infection	3	[P00533, Q13936, P02792]	METABOLITE	0.250682353
N04BX02	entacapone	C0003123	anorexia	1	[P21964]	DRUG_AND_METABOLITE	0.021793623
R01AD01	beclomethasone	C0042109	urticaria	1	[P09917]	DRUG_AND_METABOLITE	0.071706674
M01AE12	oxaprozin	C0021311	infection	2	[P35354, P23219]	DRUG	0.057974285
N02CC01	sumatriptan	C0151744	myocardial ischemia	2	[P07550, P08588]	DRUG	0.034703329
M01AH01	celecoxib	C0038454	cerebrovascular accident	2	[P28223, P35354]	DRUG_AND_METABOLITE	0.15191224
G04BE03	sildenafil	C0456909	blindness	1	[P35913]	DRUG	0.073076437
L02BB03	bicalutamide	C0010054	coronary artery disease	4	[P08684, P03372, P10275, P04150]	DRUG	2.77266E-05
L04AX04	lenalidomide	C0007785	cerebral infarction	2	[P01375, Q08499]	DRUG	0.008758372
J05AF03	zalcitabine	C0040822	tremor	1	[P54098]	METABOLITE	0.02890613
L04AX02	thalidomide	C0004093	asthenia	1	[P35354]	DRUG_AND_METABOLITE	0.104607438
C10AA05	atorvastatin	C0149931	migraine	1	[P08684]	DRUG_AND_METABOLITE	0.067555547
N02AA01	morphine	C0006826	cancer	8	[P08183, P21964, P20815, P10632, P08684, P23219, Q12809, P23975]	METABOLITE	0.296659308
N04BC02	pergolide	C0007784	cerebral hemorrhage	2	[P28223, P07550]	DRUG	0.063596471
N06AA04	clomipramine	C0026848	myopathy	2	[P17252, P29475]	METABOLITE	0.207447029
A08AA10	sibutramine	C0015230	rash	3	[P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.011918531
M01AE02	naproxen	C0009324	ulcerative colitis	2	[P31645, P35354]	DRUG	0.178422089
M01AE02	naproxen	C0009319	colitis	4	[P31645, P35354, P46098, P41595]	DRUG	0.037086334
N06AX21	duloxetine	C0015230	rash	4	[P07550, P28223, P08908, P31645]	DRUG_AND_METABOLITE	0.091827046
N02CC04	rizatriptan	C0015230	rash	2	[P28223, P08908]	DRUG_AND_METABOLITE	0.030728948
N04BD01	selegiline	C0678222	breast cancer	8	[P08684, P08183, Q99720, P05181, P05177, P20813, Q01959, P10632]	DRUG	0.428923765
L04AX02	thalidomide	C0020473	hyperlipidemia	1	[P23219]	DRUG_AND_METABOLITE	0.317679739
B01AC05	ticlopidine	C0030920	peptic ulcer	4	[P35354, P05164, P33261, P23219]	DRUG_AND_METABOLITE	6.31065E-05
A03BA01	atropine	C0013384	dyskinesia	2	[P35498, P14416]	METABOLITE	0.017783546
N05AE04	ziprasidone	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG	0
C10AB04	gemfibrozil	C0002871	anemia	1	[P07148]	DRUG	0.054879508
C09AA08	cilazapril	C0041948	uremia	1	[P12821]	DRUG	0.050504261
A02BA01	cimetidine	C1527304	allergic reaction	3	[P35367, P25021, Q9H3N8]	DRUG	0.002473457
M01AB05	diclofenac	C0018834	heartburn	1	[P23219]	DRUG_AND_METABOLITE	0.054935903
N06AA21	maprotiline	C0018524	hallucinations	1	[P08183]	DRUG	0.094288684
A10BG03	pioglitazone	C0020538	hypertension	4	[P37231, P11712, Q07869, P19793]	DRUG	0.01241697
M01AB02	sulindac	C0041582	ulcer	1	[P37231]	DRUG_AND_METABOLITE	0.039009407
M01AB05	diclofenac	C0018801	heart failure	1	[Q9Y2I1]	DRUG	0.208120547
M01AB05	diclofenac	C0018802	congestive heart failure	1	[Q9Y2I1]	DRUG	0.208120547
N03AF02	oxcarbazepine	C0013295	duodenal ulcer	1	[P33261]	DRUG	0.030786213
M01AB08	etodolac	C0038454	cerebrovascular accident	1	[P35354]	DRUG_AND_METABOLITE	0.120356457
N06AA09	amitriptyline	C0018524	hallucinations	7	[P08183, P36544, O43526, P35498, Q99250, P04156, Q9NY46]	DRUG_AND_METABOLITE	0.000141387
N06AA01	desipramine	C0019158	hepatitis	4	[P05181, P23219, P11509, P02768]	DRUG	0.005743402
L04AX04	lenalidomide	C0018681	headache	1	[P01375]	DRUG	0.039806384
N05AX08	risperidone	C0003123	anorexia	8	[P28223, P21917, P28335, P28221, P41143, P31645, P23975, P14416]	DRUG_AND_METABOLITE	0
C10AB05	fenofibrate	C0002871	anemia	1	[P07148]	DRUG_AND_METABOLITE	0.061427537
C01BA02	procainamide	C0428977	bradycardia	1	[Q14524]	DRUG	0.014460868
L04AX02	thalidomide	C0020456	hyperglycemia	3	[P19838, P35354, P01375]	DRUG	0.037810863
C07AA06	timolol	C0003123	anorexia	1	[P28223]	DRUG	0.051348531
J01MA02	ciprofloxacin	C0031117	peripheral neuropathy	1	[P08183]	DRUG	0.031878908
C07AB07	bisoprolol	C0013595	eczema	1	[P07550]	DRUG_AND_METABOLITE	0.06589552
N06AA17	amoxapine	C0009806	constipation	3	[P46098, P41595, P31645]	DRUG_AND_METABOLITE	0.00017745
L02BG03	anastrozole	C1458155	breast neoplasm	3	[P11511, P08684, P05177]	DRUG_AND_METABOLITE	0.257761716
J02AC02	itraconazole	C0023530	leukopenia	1	[P08183]	DRUG_AND_METABOLITE	0.044087091
N06BA01	amphetamine	C0009951	convulsions	6	[P14780, Q9UBS5, P36544, Q13255, P08908, P31645]	DRUG_AND_METABOLITE	0.012883405
N04BX01	tolcapone	C0085584	encephalopathy	1	[P14867]	METABOLITE	0.063596471
C09AA13	moexipril	C0013404	dyspnea	1	[P12821]	DRUG_AND_METABOLITE	0.019839873
S01EA02	dipivefrin	C0020538	hypertension	11	[P35348, P13945, P07550, P21728, O15244, P28223, P11712, P23975, P08913, P18089, P08588]	METABOLITE	0
D05BB02	acitretin	C0022116	ischemia	1	[P35354]	METABOLITE	0.11863738
B01AC07	dipyridamole	C0231528	myalgia	1	[Q08499]	DRUG	0.091808164
N06AX16	venlafaxine	C0037315	sleep apnea	1	[P31645]	DRUG_AND_METABOLITE	0.047698503
R03AC13	formoterol	C0020615	hypoglycemia	1	[P07550]	DRUG	0.032885129
A10BB07	glipizide	C0015230	rash	1	[P37231]	DRUG	0.093872815