@article{10.1371/journal.pcbi.1002381, doi = {10.1371/journal.pcbi.1002381}, author = {Elemans, Marjet AND Seich al Basatena, Nafisa-Katrin AND Asquith, Becca}, journal = {PLOS Computational Biology}, publisher = {Public Library of Science}, title = {The Efficiency of the Human CD8+ T Cell Response: How Should We Quantify It, What Determines It, and Does It Matter?}, year = {2012}, month = {02}, volume = {8}, url = {https://doi.org/10.1371/journal.pcbi.1002381}, pages = {1-7}, abstract = {Multidisciplinary techniques, in particular the combination of theoretical and experimental immunology, can address questions about human immunity that cannot be answered by other means. From the turnover of virus-infected cells in vivo, to rates of thymic production and HLA class I epitope prediction, theoretical techniques provide a unique insight to supplement experimental approaches. Here we present our opinion, with examples, of some of the ways in which mathematics has contributed in our field of interest: the efficiency of the human CD8+ T cell response to persistent viruses.}, number = {2}, }