TY - JOUR T1 - Transformation of Context-dependent Sensory Dynamics into Motor Behavior A1 - Latorre, Roberto A1 - Levi, Rafael A1 - Varona, Pablo Y1 - 2013/02/14 N2 - Author Summary How sensory information is transformed into effective motor action is one of the most fundamental questions in neuroscience. As this question is difficult to assess experimentally, biophysical models of sensory, central and motor systems contribute to understand the information processing mechanisms involved in this transformation. Biophysical models can be informed by electrophysiological data in those situations where it is possible to record neural activity at all stages of sensory-motor processing. In this paper we use this approach to describe the dual dynamics of a multifunctional sensory organ in the mollusk Clione limacina and its transformation into two different motor programs. Our experimental and modeling results indicate that the sensory signals are modified to fit the changing behavioral context, and they are readily interpreted by the rest of the nervous system to produce the correct motor output. JF - PLOS Computational Biology JA - PLOS Computational Biology VL - 9 IS - 2 UR - https://doi.org/10.1371/journal.pcbi.1002908 SP - e1002908 EP - PB - Public Library of Science M3 - doi:10.1371/journal.pcbi.1002908 ER -