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Issue Image

PLoS Computational Biology Issue Image | Vol. 3(8) August 2007

DNA damage sensing proteins In contrast to biophysical predictions, this image illustrates that "DNA damage sensing proteins" (green signal) form foci along primary cosmic rays in a regular self-excluding manner (see Costes et al, e155). Upper panel: the white dashed arrow indicates the traversal of one Fe particle in a human cell (DNA shown in blue). Middle panel: the relative position of foci (green spheres) is shown with respect to the DNA dye intensity profile visualized by a three-dimensional topographic surface. Lower panel: foci preferentially locate within low DNA nuclear density regions, or at the interface between high and low nuclear DNA densities.Image Credit: Image by Sylvain Costes.

DNA damage sensing proteins  Top

In contrast to biophysical predictions, this image illustrates that "DNA damage sensing proteins" (green signal) form foci along primary cosmic rays in a regular self-excluding manner (see Costes et al, e155). Upper panel: the white dashed arrow indicates the traversal of one Fe particle in a human cell (DNA shown in blue). Middle panel: the relative position of foci (green spheres) is shown with respect to the DNA dye intensity profile visualized by a three-dimensional topographic surface. Lower panel: foci preferentially locate within low DNA nuclear density regions, or at the interface between high and low nuclear DNA densities.

Image Credit: Image by Sylvain Costes.

Citation: (2007) PLoS Computational Biology Issue Image | Vol. 3(8) August 2007. PLoS Comput Biol 3(8): ev03.i08. doi:10.1371/image.pcbi.v03.i08

Published: August 31, 2007

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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DNA damage sensing proteins

In contrast to biophysical predictions, this image illustrates that "DNA damage sensing proteins" (green signal) form foci along primary cosmic rays in a regular self-excluding manner (see Costes et al, e155). Upper panel: the white dashed arrow indicates the traversal of one Fe particle in a human cell (DNA shown in blue). Middle panel: the relative position of foci (green spheres) is shown with respect to the DNA dye intensity profile visualized by a three-dimensional topographic surface. Lower panel: foci preferentially locate within low DNA nuclear density regions, or at the interface between high and low nuclear DNA densities.

Image Credit: Image by Sylvain Costes.

doi:10.1371/image.pcbi.v03.i08.g001
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