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Both Ligand- and Cell-Specific Parameters Control Ligand Agonism in a Kinetic Model of G Protein–Coupled Receptor Signaling

  • Tamara L Kinzer-Ursem,

    ¤ Current address: Division of Biology, California Institute of Technology, Pasadena, California, United States of America

    Affiliation Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

  • Jennifer J Linderman

    To whom correspondence should be addressed. E-mail: linderma@umich.edu

    Affiliations Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America , Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

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