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A Logical Model Provides Insights into T Cell Receptor Signaling

  • Julio Saez-Rodriguez,

    Affiliation Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany

  • Luca Simeoni,

    Affiliation Institute of Immunology, Otto-von-Guericke University, Magdeburg, Germany

  • Jonathan A Lindquist,

    Affiliation Institute of Immunology, Otto-von-Guericke University, Magdeburg, Germany

  • Rebecca Hemenway,

    Affiliation Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany

  • Ursula Bommhardt,

    Affiliation Institute of Immunology, Otto-von-Guericke University, Magdeburg, Germany

  • Boerge Arndt,

    Affiliation Institute of Immunology, Otto-von-Guericke University, Magdeburg, Germany

  • Utz-Uwe Haus,

    Affiliation Institute for Mathematical Optimization, Otto-von-Guericke University, Magdeburg, Germany

  • Robert Weismantel,

    Affiliation Institute for Mathematical Optimization, Otto-von-Guericke University, Magdeburg, Germany

  • Ernst D Gilles,

    Affiliation Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany

  • Steffen Klamt ,

    To whom correspondence should be addressed. E-mail: inquiries regarding the mathematical methodology should be addressed to Steffen Klamt, klamt@mpi-magdeburg.mpg.de, and regarding the biological and experimental data to Burkhart Schraven, Burkhart.Schraven@med.ovgu.de

    Affiliation Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany

  • Burkhart Schraven

    To whom correspondence should be addressed. E-mail: inquiries regarding the mathematical methodology should be addressed to Steffen Klamt, klamt@mpi-magdeburg.mpg.de, and regarding the biological and experimental data to Burkhart Schraven, Burkhart.Schraven@med.ovgu.de

    Affiliation Institute of Immunology, Otto-von-Guericke University, Magdeburg, Germany

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