Diminished Self-Chaperoning Activity of the ΔF508 Mutant of CFTR Results in Protein Misfolding

• Adrian W. R. Serohijos ,

  Contributed equally to this work with: Adrian W. R. Serohijos, Tamás Hegedűs

  Affiliation Department of Physics and Astronomy, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Tamás Hegedűs ,

  Contributed equally to this work with: Adrian W. R. Serohijos, Tamás Hegedűs

  Affiliations Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America, Cystic Fibrosis Research Center, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

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• John R. Riordan,

  Affiliations Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America, Cystic Fibrosis Research Center, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Nikolay V. Dokholyan

  * E-mail: dokh@med.unc.edu

  Affiliation Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

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