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Increasing the Power to Detect Causal Associations by Combining Genotypic and Expression Data in Segregating Populations

  • Jun Zhu ,

    Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America

  • Matthew C Wiener ,

    Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

  • Chunsheng Zhang ,

    Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America

  • Arthur Fridman ,

    Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

  • Eric Minch,

    Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

  • Pek Y Lum,

    Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America

  • Jeffrey R Sachs,

    Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

  • Eric E Schadt

    To whom correspondence should be addressed. E-mail: Eric_Schadt@merck.com

    Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America

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