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Research Article

Transcriptional Profiling of the Dose Response: A More Powerful Approach for Characterizing Drug Activities

  • Rui-Ru Ji mail,

    ruiruji@gmail.com

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Heshani de Silva,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Yisheng Jin,

    Affiliation: Johnson Graduate School of Management, Cornell University, Ithaca, New York, United States of America

    X
  • Robert E. Bruccoleri,

    Affiliation: Congenomics, Glastonbury, Connecticut, United States of America

    X
  • Jian Cao,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Aiqing He,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Wenjun Huang,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Paul S. Kayne,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Isaac M. Neuhaus,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Karl-Heinz Ott,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Becky Penhallow,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Mark I. Cockett,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Michael G. Neubauer,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Nathan O. Siemers,

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Petra Ross-Macdonald

    Affiliation: Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America

    X
  • Published: September 18, 2009
  • DOI: 10.1371/journal.pcbi.1000512

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