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Research Article

Predicting Protein Ligand Binding Sites by Combining Evolutionary Sequence Conservation and 3D Structure

  • John A. Capra,

    Affiliations: Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

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  • Roman A. Laskowski,

    Affiliation: European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Janet M. Thornton,

    Affiliation: European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Mona Singh mail,

    mona@cs.princeton.edu (MS); funk@cs.princeton.edu (TAF)

    Affiliations: Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

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  • Thomas A. Funkhouser mail

    mona@cs.princeton.edu (MS); funk@cs.princeton.edu (TAF)

    Affiliation: Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America

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  • Published: December 04, 2009
  • DOI: 10.1371/journal.pcbi.1000585

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