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Symmetric Allosteric Mechanism of Hexameric Escherichia coli Arginine Repressor Exploits Competition between L-Arginine Ligands and Resident Arginine Residues

  • Rebecca Strawn ,

    Contributed equally to this work with: Rebecca Strawn, Milan Melichercik

    Affiliation Chemistry Department, Princeton University, Princeton, New Jersey, United States of America

  • Milan Melichercik ,

    Contributed equally to this work with: Rebecca Strawn, Milan Melichercik

    Affiliation Department of Structure and Function of Proteins, Institute of Systems Biology and Ecology, Academy of Sciences of the Czech Republic, and Institute of Physical Biology, University of South Bohemia, Nove Hrady, Czech Republic

  • Michael Green,

    Current address: Mount Sinai School of Medicine, New York, New York, United States of America

    Affiliation Biology Department, The College of New Jersey, Ewing, New Jersey, United States of America

  • Thomas Stockner,

    Affiliation Department of Medical Chemistry, Medical University of Vienna, Vienna, Austria

  • Jannette Carey ,

    jcarey@princeton.edu (JC); ettrich@nh.usbe.cas.cz (RE)

    Affiliation Chemistry Department, Princeton University, Princeton, New Jersey, United States of America

  • Rüdiger Ettrich

    jcarey@princeton.edu (JC); ettrich@nh.usbe.cas.cz (RE)

    Affiliation Department of Structure and Function of Proteins, Institute of Systems Biology and Ecology, Academy of Sciences of the Czech Republic, and Institute of Physical Biology, University of South Bohemia, Nove Hrady, Czech Republic

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