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Research Article

Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling

  • Katarzyna A. Rejniak mail,

    Kasia.Rejniak@moffitt.org

    Affiliations: Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America, Department of Oncologic Sciences, University of South Florida College of Medicine, Tampa, Florida, United States of America

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  • Shizhen E. Wang,

    Affiliation: Division of Tumor Cell Biology, Beckman Research Institute of City of Hope, Duarte, California, United States of America

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  • Nicole S. Bryce,

    Affiliation: Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

    Current address: School of Chemistry, University of Sydney, Sydney, Australia

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  • Hang Chang,

    Affiliation: Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

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  • Bahram Parvin,

    Affiliation: Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

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  • Jerome Jourquin,

    Affiliation: Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Lourdes Estrada,

    Affiliation: Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Joe W. Gray,

    Affiliation: Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

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  • Carlos L. Arteaga,

    Affiliation: Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Alissa M. Weaver,

    Affiliation: Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Vito Quaranta equal contributor,

    equal contributor Contributed equally to this work with: Vito Quaranta, Alexander R. A. Anderson

    Affiliation: Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Alexander R. A. Anderson equal contributor

    equal contributor Contributed equally to this work with: Vito Quaranta, Alexander R. A. Anderson

    Affiliation: Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America

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  • Published: August 26, 2010
  • DOI: 10.1371/journal.pcbi.1000900

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