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Research Article

The Evolutionary Analysis of Emerging Low Frequency HIV-1 CXCR4 Using Variants through Time—An Ultra-Deep Approach

  • John Archer,

    Affiliation: Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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  • Andrew Rambaut,

    Affiliation: Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom

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  • Bruce E. Taillon,

    Affiliation: 454 Life Sciences, Branford, Connecticut, United States of America

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  • P. Richard Harrigan,

    Affiliations: British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

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  • Marilyn Lewis,

    Affiliation: Pfizer Global Research and Development, Sandwich, United Kingdom

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  • David L. Robertson mail

    david.robertson@manchester.ac.uk

    Affiliation: Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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  • Published: December 16, 2010
  • DOI: 10.1371/journal.pcbi.1001022

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