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Research Article

Reactive Oxygen Species Production by Forward and Reverse Electron Fluxes in the Mitochondrial Respiratory Chain

  • Vitaly A. Selivanov,

    Affiliations: Departament de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, and IBUB, Barcelona, Spain, A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia

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  • Tatyana V. Votyakova mail,

    tav2@pitt.edu (TVV); martacascante@ub.edu (MC)

    Affiliation: Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Diabetes Institute, Pittsburgh, Pennsylvania, United States of America

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  • Violetta N. Pivtoraiko,

    Affiliation: Neuropathology Division, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Jennifer Zeak,

    Affiliation: Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Diabetes Institute, Pittsburgh, Pennsylvania, United States of America

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  • Tatiana Sukhomlin,

    Affiliation: Institute of Theoretical and Experimental Biophysics, Pushchino, Russia

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  • Massimo Trucco,

    Affiliation: Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Diabetes Institute, Pittsburgh, Pennsylvania, United States of America

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  • Josep Roca,

    Affiliation: Hospital Clinic, IDIBAPS, CIBERES, Universitat de Barcelona, Barcelona, Catalunya, Spain

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  • Marta Cascante mail

    tav2@pitt.edu (TVV); martacascante@ub.edu (MC)

    Affiliation: Departament de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, and IBUB, Barcelona, Spain

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  • Published: March 31, 2011
  • DOI: 10.1371/journal.pcbi.1001115

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