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Research Article

An Acidic Loop and Cognate Phosphorylation Sites Define a Molecular Switch That Modulates Ubiquitin Charging Activity in Cdc34-Like Enzymes

  • Elena Papaleo mail,

    elena.papaleo@unimib.it (EP); paola.coccetti@unimib.it (PC)

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Valeria Ranzani,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Farida Tripodi,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Alessandro Vitriolo,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Claudia Cirulli,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Piercarlo Fantucci,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Lilia Alberghina,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Marco Vanoni,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Luca De Gioia,

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Paola Coccetti mail

    elena.papaleo@unimib.it (EP); paola.coccetti@unimib.it (PC)

    Affiliation: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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  • Published: May 26, 2011
  • DOI: 10.1371/journal.pcbi.1002056

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