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Research Article

Construction and Modelling of an Inducible Positive Feedback Loop Stably Integrated in a Mammalian Cell-Line

  • Velia Siciliano,

    Affiliation: Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

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  • Filippo Menolascina equal contributor,

    equal contributor Contributed equally to this work with: Filippo Menolascina, Lucia Marucci

    Affiliations: Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, Department of Computer and Systems Engineering, Federico II University, Naples, Italy

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  • Lucia Marucci equal contributor,

    equal contributor Contributed equally to this work with: Filippo Menolascina, Lucia Marucci

    Affiliations: Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, Department of Computer and Systems Engineering, Federico II University, Naples, Italy

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  • Chiara Fracassi,

    Affiliation: Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

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  • Immacolata Garzilli,

    Affiliation: Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

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  • Maria Nicoletta Moretti,

    Affiliation: Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

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  • Diego di Bernardo mail

    dibernardo@tigem.it

    Affiliations: Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, Department of Computer and Systems Engineering, Federico II University, Naples, Italy

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  • Published: June 30, 2011
  • DOI: 10.1371/journal.pcbi.1002074
  • Featured in PLOS Collections

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