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Research Article

Understanding the Origins of Bacterial Resistance to Aminoglycosides through Molecular Dynamics Mutational Study of the Ribosomal A-Site

  • Julia Romanowska mail,

    jrom@icm.edu.pl

    Affiliations: Department of Biophysics, Faculty of Physics, University of Warsaw, Warsaw Poland, Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw, Warsaw, Poland

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  • J. Andrew McCammon,

    Affiliations: Department of Chemistry and Biochemistry, University of California, San Diego, California, United States of America, Center for Theoretical Biological Physics, University of California, San Diego, California, United States of America, Department of Pharmacology, University of California, San Diego, California, United States of America, Howard Hughes Medical Institute, University of California, San Diego, California, United States of America

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  • Joanna Trylska

    Affiliation: Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw, Warsaw, Poland

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  • Published: July 21, 2011
  • DOI: 10.1371/journal.pcbi.1002099

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