Quantifying Intramolecular Binding in Multivalent Interactions: A Structure-Based Synergistic Study on Grb2-Sos1 Complex

Open Access

Peer-reviewed

Research Article

Anurag Sethi,

Affiliations Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America, Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Byron Goldstein,

Affiliation Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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S. Gnanakaran

* E-mail: gnana@lanl.gov

Affiliation Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Sequence motif analysis
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Molecular dynamics
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Polymers
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Stoichiometry
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Probability density
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SH2 domains
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Sequence alignment
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Protein interactions
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