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Research Article

Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia

  • Assieh Saadatpour,

    Affiliation: Department of Mathematics, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Rui-Sheng Wang,

    Affiliation: Department of Physics, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Aijun Liao,

    Affiliation: Penn State Hershey Cancer Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • Xin Liu,

    Affiliation: Penn State Hershey Cancer Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • Thomas P. Loughran,

    Affiliation: Penn State Hershey Cancer Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • István Albert,

    Affiliation: Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Réka Albert mail

    ralbert@phys.psu.edu

    Affiliation: Department of Physics, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Published: November 10, 2011
  • DOI: 10.1371/journal.pcbi.1002267

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