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Research Article

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

  • Feixiong Cheng equal contributor,

    equal contributor Contributed equally to this work with: Feixiong Cheng, Chuang Liu

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Chuang Liu equal contributor,

    equal contributor Contributed equally to this work with: Feixiong Cheng, Chuang Liu

    Affiliation: School of Business, East China University of Science and Technology, Shanghai, China

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  • Jing Jiang,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Weiqiang Lu,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Weihua Li,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Guixia Liu,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Weixing Zhou mail,

    wxzhou@ecust.edu.cn (WZ); huangjin@ecust.edu.cn (JH); ytang234@ecust.edu.cn (YT)

    Affiliation: School of Business, East China University of Science and Technology, Shanghai, China

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  • Jin Huang mail,

    wxzhou@ecust.edu.cn (WZ); huangjin@ecust.edu.cn (JH); ytang234@ecust.edu.cn (YT)

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Yun Tang mail

    wxzhou@ecust.edu.cn (WZ); huangjin@ecust.edu.cn (JH); ytang234@ecust.edu.cn (YT)

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Published: May 10, 2012
  • DOI: 10.1371/journal.pcbi.1002503

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